High dimensional longitudinal data analysis with Markov Chain Monte Carlo(MCMC). Currently support mixed effect regression with or without missing observations by considering covariance structures. It provides estimates by missing at random and missing not at random assumptions. In this R package, we present Bayesian approaches that statisticians and clinical researchers can easily use. The functions methodology is based on the book "Bayesian Approaches in Oncology Using R and OpenBUGS" by Bhattacharjee A (2020) <doi:10.1201/9780429329449-14>.

This package provides tools for detecting and correcting sample mix-ups between two sets of measurements, such as between gene expression data on two tissues. Broman et al. (2015) <doi:10.1534/g3.115.019778>.

Persistent reproducible reporting by containerization of R Markdown documents.

Alternate font rendering is useful when rendering text to novel graphics outputs where modern font rendering is not available or where bespoke text positioning is required. Bitmap and vector fonts allow for custom layout and rendering using pixel coordinates and line drawing. Formatted text is created as a data.frame of pixel coordinates (for bitmap fonts) or stroke coordinates (for vector fonts). All text can be easily previewed as a matrix or raster image. A selection of fonts is included with this package.

Framework for adding authentication to shiny applications. Provides flexibility as compared to other options for where user credentials are saved, allows users to create their own accounts, and password reset functionality. Bryer (2024) <doi:10.5281/zenodo.10987876>.

Automatically install, update, and load CRAN', GitHub', and Bioconductor packages in a single function call. By accepting bare unquoted names for packages, it's easy to add or remove packages from the list.

This package provides methods for estimation and statistical inference on directional and fluctuating selection in age-structured populations.

Bootstrap routines for nested linear mixed effects models fit using either lme4 or nlme'. The provided bootstrap() function implements the parametric, residual, cases, random effect block (REB), and wild bootstrap procedures. An overview of these procedures can be found in Van der Leeden et al. (2008) <doi: 10.1007/978-0-387-73186-5_11>, Carpenter, Goldstein & Rasbash (2003) <doi: 10.1111/1467-9876.00415>, and Chambers & Chandra (2013) <doi: 10.1080/10618600.2012.681216>.

This computes Lipinski Rule of Five parameters and offers visualization for drug discovery. It analyzes molecular properties like molecular weight, hydrogen bond donors, acceptors, and ALogP, providing histograms and pass/fail status plots for efficient compound evaluation, aiding in drug development.

This package provides methods of developing linear time series modelling. Methods are given for loglikelihood computation, forecasting and simulation.

This package contains (1) event-related brain potential data recorded from 10 participants at electrodes Fz, Cz, Pz, and Oz (0--300 ms) in the context of Antoine Tremblay's PhD thesis (Tremblay, 2009); (2) ERP amplitudes at electrode Fz restricted to the 100 to 175 millisecond time window; and (3) plotting data generated from a linear mixed-effects model.

Runtime for serving containers that can execute R code on the AWS Lambda serverless compute service <https://aws.amazon.com/lambda/>. Provides the necessary functionality for handling the various endpoints required for accepting new input and sending responses.

Logic Forest is an ensemble machine learning method that identifies important and interpretable combinations of binary predictors using logic regression trees to model complex relationships with an outcome. Wolf, B.J., Slate, E.H., Hill, E.G. (2010) <doi:10.1093/bioinformatics/btq354>.

Calculates landscape metrics for categorical landscape patterns in a tidy workflow. landscapemetrics reimplements the most common metrics from FRAGSTATS (<https://www.fragstats.org/>) and new ones from the current literature on landscape metrics. This package supports terra SpatRaster objects as input arguments. It further provides utility functions to visualize patches, select metrics and building blocks to develop new metrics.

This package provides functions to estimate the intensity function and its derivative of a given order of a multiplicative counting process using the local polynomial method.

Classical tests of goodness-of-fit aim to validate the conformity of a postulated model to the data under study. In their standard formulation, however, they do not allow exploring how the hypothesized model deviates from the truth nor do they provide any insight into how the rejected model could be improved to better fit the data. To overcome these shortcomings, we establish a comprehensive framework for goodness-of-fit which naturally integrates modeling, estimation, inference and graphics. In this package, the deviance tests and comparison density plots are performed to conduct the LP smoothed inference, where the letter L denotes nonparametric methods based on quantiles and P stands for polynomials. Simulations methods are used to perform variance estimation, inference and post-selection adjustments. Algeri S. and Zhang X. (2020) <arXiv:2005.13011>.

Package shiny provides interactive web applications in R. Package loon is an interactive toolkit engaged in open-ended, creative and unscripted data exploration. The loon.shiny package can take loon widgets and display a selfsame shiny app.

An implementation of the Log Cumulative Probability Model (LCPM) and Proportional Probability Model (PPM) for which the Maximum Likelihood Estimates are determined using constrained optimization. This implementation accounts for the implicit constraints on the parameter space. Other features such as standard errors, z tests and p-values use standard methods adapted from the results based on constrained optimization.

Fit relationship-based and customized mixed-effects models with complex variance-covariance structures using the lme4 machinery. The core computational algorithms are implemented using the Eigen C++ library for numerical linear algebra and RcppEigen glue'.

Estimates two-dimensional local wavelet spectra.

Convenient aliases for common ways of misspelling the base R function length(). These include every permutation of the final three letters.

Estimate haplotypic or composite pairwise linkage disequilibrium (LD) in polyploids, using either genotypes or genotype likelihoods. Support is provided to estimate the popular measures of LD: the LD coefficient D, the standardized LD coefficient D', and the Pearson correlation coefficient r. All estimates are returned with corresponding standard errors. These estimates and standard errors can then be used for shrinkage estimation. The main functions are ldfast(), ldest(), mldest(), sldest(), plot.lddf(), format_lddf(), and ldshrink(). Details of the methods are available in Gerard (2021a) <doi:10.1111/1755-0998.13349> and Gerard (2021b) <doi:10.1038/s41437-021-00462-5>.

This package performs variety of viral quasispecies diversity analyses [see Pamornchainavakul et al. (2024) <doi:10.21203/rs.3.rs-4637890/v1>] based on long-read sequence alignment. Main functions include 1) sequencing error and other noise minimization and read sampling, 2) Single nucleotide variant (SNV) profiles comparison, and 3) viral quasispecies profiles comparison and visualization.

Palettes generated from limnology based field and laboratory photos. Palettes can be used to generate color values to be used in any functions that calls for a color (i.e. ggplot(), plot(), flextable(), etc.).