Testing CRAN and Bioconductor mirror speed by recording download time of src/base/COPYING (for CRAN) and packages/release/bioc/html/ggtree.html (for Bioconductor).

Package for combined miRNA- and mRNA-testing.

This package provides functions for detecting multicollinearity. This test gives statistical support to two of the most famous methods for detecting multicollinearity in applied work: Kleinâ s rule and Variance Inflation Factor (VIF). See the URL for the papers associated with this package, as for instance, Morales-Oñate and Morales-Oñate (2015) <doi:10.33333/rp.vol51n2.05>.

Based on the work of Curi, Converse, Hajewski, and Oliveira (2019) <doi:10.1109/IJCNN.2019.8852333>. This package provides easy-to-use functions which create a variational autoencoder (VAE) to be used for parameter estimation in Item Response Theory (IRT) - namely the Multidimensional Logistic 2-Parameter (ML2P) model. To use a neural network as such, nontrivial modifications to the architecture must be made, such as restricting the nonzero weights in the decoder according to some binary matrix Q. The functions in this package allow for straight-forward construction, training, and evaluation so that minimal knowledge of tensorflow or keras is required.

Provide a suite of functions for conducting and automating Latent Growth Modeling (LGM) in Mplus', including Growth Curve Model (GCM), Growth-Based Trajectory Model (GBTM) and Latent Class Growth Analysis (LCGA). The package builds upon the capabilities of the MplusAutomation package (Hallquist & Wiley, 2018) to streamline large-scale latent variable analyses. âMplusAutomation: An R Package for Facilitating Large-Scale Latent Variable Analyses in Mplus.â Structural Equation Modeling, 25(4), 621â 638. <doi:10.1080/10705511.2017.1402334> The workflow implemented in this package follows the recommendations outlined in Van Der Nest et al. (2020). â An Overview of Mixture Modeling for Latent Evolutions in Longitudinal Data: Modeling Approaches, Fit Statistics, and Software.â Advances in Life Course Research, 43, Article 100323. <doi:10.1016/j.alcr.2019.100323>.

This package provides functions to support data cleaning, evaluation, and description, developed for integration with Maelstrom Research software tools. madshapR provides functions primarily to evaluate and manipulate datasets and data dictionaries in preparation for data harmonization with the package Rmonize and to facilitate integration and transfer between RStudio servers and secure Opal environments. madshapR functions can be used independently but are optimized in conjunction with â Rmonizeâ functions for streamlined and coherent harmonization processing.

Algorithms for multivariate outlier detection when missing values occur. Algorithms are based on Mahalanobis distance or data depth. Imputation is based on the multivariate normal model or uses nearest neighbour donors. The algorithms take sample designs, in particular weighting, into account. The methods are described in Bill and Hulliger (2016) <doi:10.17713/ajs.v45i1.86>.

Package to carry out merged block randomization (Van der Pas (2019), <doi:10.1177/1740774519827957>), a restricted randomization method designed for small clinical trials (at most 100 subjects) or trials with small strata, for example in multicentre trials. It can be used for more than two groups or unequal randomization ratios.

Estimation equations are from a variety of sources and associated error estimation.

Multivariate functional principal component analysis via fast covariance estimation for multivariate sparse functional data or longitudinal data proposed by Li, Xiao, and Luo (2020) <doi: 10.1002/sta4.245>.

Predictive multivariate modelling for metabolomics. Types: Classification and regression. Methods: Partial Least Squares, Random Forest ans Elastic Net Data structures: Paired and unpaired Validation: repeated double cross-validation (Westerhuis et al. (2008)<doi:10.1007/s11306-007-0099-6>, Filzmoser et al. (2009)<doi:10.1002/cem.1225>) Variable selection: Performed internally, through tuning in the inner cross-validation loop.

This package provides a function for measuring the difference between two independent or non-independent empirical distributions and returning a significance level of the difference.

Generate maximum projection (MaxPro) designs for quantitative and/or qualitative factors. Details of the MaxPro criterion can be found in: (1) Joseph, Gul, and Ba. (2015) "Maximum Projection Designs for Computer Experiments", Biometrika, 102, 371-380, and (2) Joseph, Gul, and Ba. (2018) "Designing Computer Experiments with Multiple Types of Factors: The MaxPro Approach", Journal of Quality Technology, to appear.

This package provides tools for general-purpose continuous optimization and feed-forward artificial neural network training using metaheuristic and gradient-based optimization algorithms. The package supports benchmark function optimization, regression, binary classification, and multi-class classification with multilayer perceptrons. The package implements several optimization methods, including particle swarm optimization Kennedy and Eberhart (1995) <doi:10.1109/ICNN.1995.488968>, differential evolution Storn and Price (1997) <doi:10.1023/A:1008202821328>, grey wolf optimizer Mirjalili et al. (2014) <doi:10.1016/j.advengsoft.2013.12.007>, secretary bird optimization Fu et al. (2024) <doi:10.1007/s10462-024-10729-y>, and Adam Kingma and Ba (2015) <doi:10.48550/arXiv.1412.6980>.

Model evaluation based on a modified version of the recursive feature elimination algorithm. This package is designed to determine the optimal model(s) by leveraging all available features.

Clustering of data under a non-ignorable missingness mechanism. Clustering is achieved by a semi-parametric mixture model and missingness is managed by using the pattern-mixture approach. More details of the approach are available in Du Roy de Chaumaray et al. (2020) <arXiv:2009.07662>.

Evaluate whether a microbiome sample is a mixture of two samples, by fitting a model for the number of read counts as a function of single nucleotide polymorphism (SNP) allele and the genotypes of two potential source samples. Lobo et al. (2021) <doi:10.1093/g3journal/jkab308>.

Quantifies ecological memory in long time-series using Random Forest models ('Benito', Gil-Romera', and Birks 2019 <doi:10.1111/ecog.04772>) fitted with ranger (Wright and Ziegler 2017 <doi:10.18637/jss.v077.i01>). Ecological memory is assessed by modeling a response variable as a function of lagged predictors, distinguishing endogenous memory (lagged response) from exogenous memory (lagged environmental drivers). Designed for palaeoecological datasets and simulated pollen curves from virtualPollen', but applicable to any long time-series with environmental drivers and a biotic response.

Local adaptation and evaluation of maps of continuous attributes in raster format by use of point location data.

Utility functions for discovering and managing metadata associated with spatially unique "known locations". Applications include all fields of environmental monitoring (e.g. air and water quality) where data are collected at stationary sites.

Exports two functions implementing multi-way clustering using the method suggested by Cameron, Gelbach, & Miller (2011) and cluster (or block) bootstrapping for estimating variance-covariance matrices. Normal one and two-way clustering matches the results of other common statistical packages. Missing values are handled transparently and rudimentary parallelization support is provided.

This package implements differential methylation region (DMR) detection using a multistage Markov chain Monte Carlo (MCMC) algorithm based on the alpha-skew generalized normal (ASGN) distribution. Version 0.2.0 removes the Anderson-Darling test stage, improves computational efficiency of the core ASGN and multistage MCMC routines, and adds convenience functions for summarizing and visualizing detected DMRs. The methodology is based on Yang (2025) <https://www.proquest.com/docview/3218878972>.

This package provides functionality to generate compound optimal designs for targeting the multiple experimental objectives directly, ensuring that the full set of research questions is answered as economically as possible. Designs can be found using point or coordinate exchange algorithms combining estimation, inference and lack-of-fit criteria that account for model inadequacy. Details and examples are given by Koutra et al. (2024) <doi:10.48550/arXiv.2412.17158>.

Set of utility functions to interact with WeMo Switch', a smart plug that can be remotely controlled via wifi. The provided functions make it possible to turn one or more WeMo Switch plugs on and off in a scriptable fashion. More information about WeMo Switch can be found at <http://www.belkin.com/us/p/P-F7C027/>.