This package provides a set of functions to support experimentation in the utility of partially synthetic data sets. All functions compare an observed data set to one or a set of partially synthetic data sets derived from the observed data to (1) check that data sets have identical attributes, (2) calculate overall and specific variable perturbation rates, (3) check for potential logical inconsistencies, and (4) calculate confidence intervals and standard errors of desired variables in multiple imputed data sets. Confidence interval and standard error formulas have options for either synthetic data sets or multiple imputed data sets. For more information on the formulas and methods used, see Reiter & Raghunathan (2007) <doi:10.1198/016214507000000932>.

This package provides a covariance estimator for multivariate normal data that is sparse and positive definite. Implements the majorize-minimize algorithm described in Bien, J., and Tibshirani, R. (2011), "Sparse Estimation of a Covariance Matrix," Biometrika. 98(4). 807--820.

This package provides functions to manipulate PDF files: fill out PDF forms; merge multiple PDF files into one; remove selected pages from a file; rename multiple files in a directory; rotate entire pdf document; rotate selected pages of a pdf file; Select pages from a file; splits single input PDF document into individual pages; splits single input PDF document into parts from given points.

Sensitivity analysis in unmatched observational studies, with or without strata. The main functions are sen2sample() and senstrat(). See Rosenbaum, P. R. and Krieger, A. M. (1990), JASA, 85, 493-498, <doi:10.1080/01621459.1990.10476226> and Gastwirth, Krieger and Rosenbaum (2000), JRSS-B, 62, 545â 555 <doi:10.1111/1467-9868.00249> .

This package implements a segmentation algorithm for multiple change-point detection in high-dimensional GARCH processes. It simultaneously segments GARCH processes by identifying common change-points, each of which can be shared by a subset or all of the component time series as a change-point in their within-series and/or cross-sectional correlation structure.

Dictionary-like reference for computing scoring rules in a wide range of situations. Covers both parametric forecast distributions (such as mixtures of Gaussians) and distributions generated via simulation. Further details can be found in the package vignettes <doi:10.18637/jss.v090.i12>, <doi:10.18637/jss.v110.i08>.

This package provides methods focused in performing the OSGB36/ETRS89 transformation (Great Britain and the Isle of Man only) by using the Ordnance Survey's OSTN15/OSGM15 transformation model. Calculation of distances and areas from sets of points defined in any of the supported Coordinated Systems is also available.

Implementation of sequential trial emulation for the analysis of observational databases. The SEQTaRget software accommodates time-varying treatments and confounders, as well as binary and failure time outcomes. SEQTaRget allows to compare both static and dynamic strategies, can be used to estimate observational analogs of intention-to-treat and per-protocol effects, and can adjust for potential selection bias induced by losses-to-follow-up. (Paper to come).

This package provides a tool for survival analysis using a discrete time approach with ensemble binary classification. spect provides a simple interface consistent with commonly used R data analysis packages, such as caret', a variety of parameter options to help facilitate search automation, a high degree of transparency to the end-user - all intermediate data sets and parameters are made available for further analysis and useful, out-of-the-box visualizations of model performance. Methods for transforming survival data into discrete-time are adapted from the autosurv package by Suresh et al., (2022) <doi:10.1186/s12874-022-01679-6>.

Allows user to conduct a simulation based quantitative bias analysis using covariate structures generated with individual-level data to characterize the bias arising from unmeasured confounding. Users can specify their desired data generating mechanisms to simulate data and quantitatively summarize findings in an end-to-end application using this package.

Analysis of multivariate environmental high frequency data by Self-Organizing Map and k-means clustering algorithms. By means of the graphical user interface it provides a comfortable way to elaborate by self-organizing map algorithm rather big datasets (txt files up to 100 MB ) obtained by environmental high-frequency monitoring by sensors/instruments. The functions present in the package are based on kohonen and openair packages implemented by functions embedding Vesanto et al. (2001) <http://www.cis.hut.fi/projects/somtoolbox/package/papers/techrep.pdf> heuristic rules for map initialization parameters, k-means clustering algorithm and map features visualization. Cluster profiles visualization as well as graphs dedicated to the visualization of time-dependent variables Licen et al. (2020) <doi:10.4209/aaqr.2019.08.0414> are provided.

Spatial model calculation for static and dynamic panel data models, weights matrix creation and Bayesian model comparison. Bayesian model comparison methods were described by LeSage (2014) <doi:10.1016/j.spasta.2014.02.002>. The Lee'-'Yu transformation approach is described in Yu', De Jong and Lee (2008) <doi:10.1016/j.jeconom.2008.08.002>, Lee and Yu (2010) <doi:10.1016/j.jeconom.2009.08.001> and Lee and Yu (2010) <doi:10.1017/S0266466609100099>.

This is an interface for the Python package StepMix'. It is a Python package following the scikit-learn API for model-based clustering and generalized mixture modeling (latent class/profile analysis) of continuous and categorical data. StepMix handles missing values through Full Information Maximum Likelihood (FIML) and provides multiple stepwise Expectation-Maximization (EM) estimation methods based on pseudolikelihood theory. Additional features include support for covariates and distal outcomes, various simulation utilities, and non-parametric bootstrapping, which allows inference in semi-supervised and unsupervised settings. Software paper available at <doi:10.18637/jss.v113.i08>.

This package provides tools for reading and writing biological sequences in multiple formats, including FASTA', PHYLIP', CLUSTAL', STOCKHOLM', MEGA and GenBank'. Supports interleaved and sequential layouts where applicable, converts between formats, and manipulates sequence sets (e.g., filtering by patterns and computing consensus sequences from alignments). Also includes functions to download nucleotide records from NCBI by accession.

Standard RGB spaces included are sRGB, Adobe RGB, ProPhoto RGB, BT.709, and others. User-defined RGB spaces are also possible. There is partial support for ACES Color workflows.

Calculates the power and sample size based on the difference in Restricted Mean Survival Time.

An exact method for computing the Poisson-Binomial Distribution (PBD). The package provides a function for generating a random sample from the PBD, as well as two distinct approaches for computing the density, distribution, and quantile functions of the PBD. The first method uses direct-convolution, or a dynamic-programming approach which is numerically stable but can be slow for a large input due to its quadratic complexity. The second method is much faster on large inputs thanks to its use of Fast Fourier Transform (FFT) based convolutions. Notably in this case the package uses an exponential shift to practically guarantee the relative accuracy of the computation of an arbitrarily small tail of the PBD -- something that FFT-based methods often struggle with. This ShiftConvolvePoiBin method is described in Peres, Lee and Keich (2020) <arXiv:2004.07429> where it is also shown to be competitive with the fastest implementations for exactly computing the entire Poisson-Binomial distribution.

Automates the creation of Dockerfiles for deploying Shiny applications. By integrating with renv for dependency management and leveraging Docker-based solutions, it simplifies the process of containerizing Shiny apps, ensuring reproducibility and consistency across different environments. Additionally, it facilitates the setup of CI/CD pipelines for building Docker images on both GitLab and GitHub.

Easily analyze and visualize the performance of symptom checkers. This package can be used to gain comprehensive insights into the performance of single symptom checkers or the performance of multiple symptom checkers. It can be used to easily compare these symptom checkers across several metrics to gain an understanding of their strengths and weaknesses. The metrics are developed in Kopka et al. (2023) <doi:10.1177/20552076231194929>.

This package provides functions that wrap HTML Bootstrap components code to enable the design and layout of informative landing home pages for Shiny applications. This can lead to a better user experience for the users and writing less HTML for the developer.

Collection of stepwise procedures to conduct multiple hypotheses testing. The details of the stepwise algorithm can be found in Romano and Wolf (2007) <DOI:10.1214/009053606000001622> and Hsu, Kuan, and Yen (2014) <DOI:10.1093/jjfinec/nbu014>.

Supports the calculation of meteorological characteristics in evapotranspiration research and reference crop evapotranspiration, and offers three models to simulate crop evapotranspiration and soil water balance in the field, including single crop coefficient and dual crop coefficient, as well as the Shuttleworth-Wallace model. These calculations main refer to Allen et al.(1998, ISBN:92-5-104219-5), Teh (2006, ISBN:1-58-112-998-X), and Liu et al.(2006) <doi:10.1016/j.agwat.2006.01.018>.

Streamlined workflow from deconvolution of bulk RNA-seq data to downstream differential expression and gene-set enrichment analysis. Provide various visualization functions.

Wrapper for the non-validating SQL parser Python module sqlparse <https://github.com/andialbrecht/sqlparse>. It allows parsing, splitting, and formatting SQL statements.