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Computes probabilities of the bivariate normal distribution in a vectorized R function (Drezner & Wesolowsky, 1990, <doi:10.1080/00949659008811236>).
Set of functions that implement the PoDBAY method, described in the publication A method to estimate probability of disease and vaccine efficacy from clinical trial immunogenicity data by Julie Dudasova, Regina Laube, Chandni Valiathan, Matthew C. Wiener, Ferdous Gheyas, Pavel Fiser, Justina Ivanauskaite, Frank Liu and Jeffrey R. Sachs (NPJ Vaccines, 2021), <doi:10.1038/s41541-021-00377-6>.
Permutation (randomisation) test for single-case phase design data with two phases (e.g., pre- and post-treatment). Correction for dependency of observations is done through stepwise resampling the time series while varying the distance between observations. The required distance 0,1,2,3.. is determined based on repeated dependency testing while stepwise increasing the distance. In preparation: Vroegindeweij et al. "A Permutation distancing test for single-case observational AB phase design data: A Monte Carlo simulation study".
This package provides high-level API and a wide range of options to create stunning, publication-quality plots effortlessly. It is built upon ggplot2 and other plotting packages, and is designed to be easy to use and to work seamlessly with ggplot2 objects. It is particularly useful for creating complex plots with multiple layers, facets, and annotations. It also provides a set of functions to create plots for specific types of data, such as Venn diagrams, alluvial diagrams, and phylogenetic trees. The package is designed to be flexible and customizable, and to work well with the ggplot2 ecosystem. The API can be found at <https://pwwang.github.io/plotthis/reference/index.html>.
All PubChem compounds are downloaded to a local computer, but for each compound, only partial records are used. The data are organized into small files referenced by PubChem CID. This package also contains functions to parse the biologically relevant compounds from all PubChem compounds, using biological database sources, pathway presence, and taxonomic relationships. Taxonomy is used to generate a lowest common ancestor taxonomy ID (NCBI) for each biological metabolite, which then enables creation of taxonomically specific metabolome databases for any taxon.
Fast exponentiation when the exponent is an integer.
This package contains the core methods for the evaluation of principal surrogates in a single clinical trial. Provides a flexible interface for defining models for the risk given treatment and the surrogate, the models for integration over the missing counterfactual surrogate responses, and the estimation methods. Estimated maximum likelihood and pseudo-score can be used for estimation, and the bootstrap for inference. A variety of post-estimation summary methods are provided, including print, summary, plot, and testing.
Mixtures of Poisson Generalized Linear Models for high dimensional count data clustering. The (multivariate) responses can be partitioned into set of blocks. Three different parameterizations of the linear predictor are considered. The models are estimated according to the EM algorithm with an efficient initialization scheme <doi:10.1016/j.csda.2014.07.005>.
This package provides functions to estimate the kinship matrix of individuals from a large set of biallelic SNPs, and extract inbreeding coefficients and the generalized FST (Wright's fixation index). Method described in Ochoa and Storey (2021) <doi:10.1371/journal.pgen.1009241>.
This package provides a collection of easy-to-use tools for regression analysis of survival data with a cure fraction proposed in Su et al. (2022) <doi:10.1177/09622802221108579>. The modeling framework is based on the Cox proportional hazards mixture cure model and the bounded cumulative hazard (promotion time cure) model. The pseudo-observations approach is utilized to assess covariate effects and embedded in the variable selection procedure.
This package provides a shiny app that supports merging of PDF and/or image files with page selection, removal, or rotation options. It is a fast, free, and secure alternative to commercial software or various online websites which require users to sign-up, and it avoids any potential risks associated with uploading files elsewhere.
An R implementation of methods employed in the field of pedometrics, soil science discipline dedicated to studying the spatial, temporal, and spatio-temporal variation of soil using statistical and computational methods. The methods found here include the calibration of linear regression models using covariate selection strategies, computation of summary validation statistics for predictions, generation of summary plots, evaluation of the local quality of a geostatistical model of uncertainty, and so on. Other functions simply extend the functionalities of or facilitate the usage of functions from other packages that are commonly used for the analysis of soil data. Formerly available versions of suggested packages no longer available from CRAN can be obtained from the CRAN archive <https://cran.r-project.org/src/contrib/Archive/>.
Test-based Image structural similarity measure and test of independence. This package implements the key functions of two tasks: (1) computing image structural similarity measure PSSIM of Wang, Maldonado and Silwal (2011) <DOI:10.1016/j.csda.2011.04.021>; and (2) test of independence between a response and a covariate in presence of heteroscedastic treatment effects proposed by Wang, Tolos, and Wang (2010) <DOI:10.1002/cjs.10068>.
This takes in a series of multi-layer raster files and returns a phenology projection raster, following methodologies described in John (2016) <https://etda.libraries.psu.edu/catalog/13521clj5135>.
Read, process, fit, and analyze photosynthetic gas exchange measurements. Documentation is provided by several vignettes; also see Lochocki, Salesse-Smith, & McGrath (2025) <doi:10.1111/pce.15501>.
Power logit regression models for bounded continuous data, in which the density generator may be normal, Student-t, power exponential, slash, hyperbolic, sinh-normal, or type II logistic. Diagnostic tools associated with the fitted model, such as the residuals, local influence measures, leverage measures, and goodness-of-fit statistics, are implemented. The estimation process follows the maximum likelihood approach and, currently, the package supports two types of estimators: the usual maximum likelihood estimator and the penalized maximum likelihood estimator. More details about power logit regression models are described in Queiroz and Ferrari (2022) <arXiv:2202.01697>.
This package provides a collection of functions for modelling mutations in pedigrees with marker data, as used e.g. in likelihood computations with microsatellite data. Implemented models include equal, proportional and stepwise models, as well as random models for experimental work, and custom models allowing the user to apply any valid mutation matrix. Allele lumping is done following the lumpability criteria of Kemeny and Snell (1976), ISBN:0387901922.
Price volatility refers to the degree of variation in series over a certain period of time. This volatility is especially noticeable in agricultural commodities, adding uncertainty for farmers, traders, and others in the agricultural supply chain. Commonly and popularly used four volatility models viz, GARCH, Glosten Jagannatan Runkle-GARCH (GJR-GARCH) model, exponentially weighted moving average (EWMA) model and Multiplicative Error Model (MEM) are selected and implemented. PWAVE, weighted ensemble model based on particle swarm optimization (PSO) is proposed to combine the forecast obtained from all the candidate models. This package has been developed using algorithm of Paul et al. <doi:10.1007/s40009-023-01218-x> and Yeasin and Paul (2024) <doi:10.1007/s11227-023-05542-3>.
Download economic and financial time series from public sources, including the St Louis Fed's FRED system, Yahoo Finance, the US Bureau of Labor Statistics, the US Energy Information Administration, the World Bank, Eurostat, the European Central Bank, the Bank of England, the UK's Office of National Statistics, Deutsche Bundesbank, and INSEE.
This package implements sparse regression with paired covariates (<doi:10.1007/s11634-019-00375-6>). The paired lasso is designed for settings where each covariate in one set forms a pair with a covariate in the other set (one-to-one correspondence). For the optional correlation shrinkage, install ashr (<https://github.com/stephens999/ashr>) and CorShrink (<https://github.com/kkdey/CorShrink>) from GitHub (see README).
Normalization of numerical matrices by minimizing the mean/median/mode difference between all column pairs.
This package provides functions for easily reading and processing binary data files created by Pamguard (<https://www.pamguard.org/>). All functions for directly reading the binary data files are based on MATLAB code written by Michael Oswald.
This package provides a fully legal chess move generator and game engine implemented in C++17 via Rcpp'. Provides FEN (Forsyth-Edwards Notation) parsing, PGN (Portable Game Notation) replay, position feature enrichment, and a multi-game registry backed by a bitboard representation.
Simulates pooled sequencing data under a variety of conditions. Also allows for the evaluation of the average absolute difference between allele frequencies computed from genotypes and those computed from pooled data. Carvalho et al., (2022) <doi:10.1101/2023.01.20.524733>.