In clinical trials, endpoints are sometimes evaluated with uncertainty. Adjudication is commonly adopted to ensure the study integrity. We propose to use multiple imputation (MI) introduced by Robin (1987) <doi:10.1002/9780470316696> to incorporate these uncertainties if reasonable event probabilities were provided. The method has been applied to Cox Proportional Hazard (PH) model, Kaplan-Meier (KM) estimation and Log-rank test in this package. Moreover, weighted estimations discussed in Cook (2004) <doi:10.1016/S0197-2456(00)00053-2> were also implemented with weights calculated from event probabilities. In conclusion, this package can handle time-to-event analysis if events presented with uncertainty by different methods.

An implementation of split-population duration regression models. Unlike regular duration models, split-population duration models are mixture models that accommodate the presence of a sub-population that is not at risk for failure, e.g. cancer patients who have been cured by treatment. This package implements Weibull and Loglogistic forms for the duration component, and focuses on data with time-varying covariates. These models were originally formulated in Boag (1949) and Berkson and Gage (1952), and extended in Schmidt and Witte (1989).

Settings and functions to extend the knitr Stata engine.

Secure handling of API keys can be difficult. This package provides secure convenience functions for entering / handling API keys and opening connections via inversion of control on those keys. Works seamlessly between production and developer environments.

This package provides a comprehensive, modular framework for computing the Soil Quality Index (SQI) using six established methods: Linear Scoring (Doran and Parkin, 1994, <doi:10.2136/sssaspecpub35.c1>), Regression-based (Masto et al., 2008, <doi:10.1007/s10661-007-9697-z>), Principal Component Analysis-based (Andrews et al., 2004, <doi:10.2136/sssaj2004.1945>), Fuzzy Logic, Entropy Weighting (Shannon, 1948, <doi:10.1002/j.1538-7305.1948.tb01338.x>), and TOPSIS (Hwang and Yoon, 1981, <doi:10.1007/978-3-642-48318-9>). Implements four variable scoring functions: more-is-better, less-is-better, optimum-value, and trapezoidal, following Karlen and Stott (1994, <doi:10.2136/sssaspecpub35.c4>). Includes automated Minimum Data Set selection via Principal Component Analysis with Variance Inflation Factor filtering (Kaiser, 1960, <doi:10.1177/001316446002000116>), one-way ANOVA with Tukey HSD post-hoc tests, leave-one-out sensitivity analysis, and publication-quality visualization using ggplot2'.

We introduce improved methods for statistically assessing birth seasonality and intra-annual variation. The first method we propose is a new idea that uses a nonparametric clustering procedure to group individuals with similar time series data and estimate birth seasonality based on the clusters. One can use the function SCEM() to implement this method. The second method estimates input parameters for use with a previously-developed parametric approach (Tornero et al., 2013). The relevant code for this approach is makeFits_OLS(), while makeFits_initial() is the code to implement the same method but with given initial conditions for two parameters. The latter can be used to show the disadvantage of the existing approach. One can use the function makeFits() to generate parametric birth seasonality estimates using either initialization. Detailed description can be found here: Chazin Hannah, Soudeep Deb, Joshua Falk, and Arun Srinivasan (2019) <doi:10.1111/arcm.12432> "New Statistical Approaches to Intra-Individual Isotopic Analysis and Modeling Birth Seasonality in Studies of Herd Animals".

This package provides functions for reading and writing Gadget N-body snapshots. The Gadget code is popular in astronomy for running N-body / hydrodynamical cosmological and merger simulations. To find out more about Gadget see the main distribution page at www.mpa-garching.mpg.de/gadget/.

This package provides a simple package facilitating ML based analysis for physics education research (PER) purposes. The implemented machine learning technique is random forest optimized by item response theory (IRT) for feature selection and genetic algorithm (GA) for hyperparameter tuning. The data analyzed here has been made available in the CRAN repository through the spheredata package. The SPHERE stands for Students Performance in Physics Education Research (PER). The students are the eleventh graders learning physics at the high school curriculum. We follow the stream of multidimensional students assessment as probed by some research based assessments in PER. The goal is to predict the students performance at the end of the learning process. Three learning domains are measured including conceptual understanding, scientific ability, and scientific attitude. Furthermore, demographic backgrounds and potential variables predicting students performance on physics are also demonstrated.

This package provides functionalities for performing stability analysis of genotype by environment interaction (GEI) to identify superior and stable genotypes across diverse environments. It implements Eberhart and Russellâ s ANOVA method (1966)(<doi:10.2135/cropsci1966.0011183X000600010011x>), Finlay and Wilkinsonâ s Joint Linear Regression method (1963) (<doi:10.1071/AR9630742>), Wrickeâ s Ecovalence (1962, 1964), Shuklaâ s stability variance parameter (1972) (<doi:10.1038/hdy.1972.87>), Kangâ s simultaneous selection for high yield and stability (1991) (<doi:10.2134/agronj1991.00021962008300010037x>), Additive Main Effects and Multiplicative Interaction (AMMI) method and Genotype plus Genotypes by Environment (GGE) Interaction methods.

R language bindings for SolveBio's API. SolveBio is a biomedical knowledge hub that enables life science organizations to collect and harmonize the complex, disparate "multi-omic" data essential for today's R&D and BI needs.

Models high-dimensional data, such as RNA-seq or proteomic data using an item-by-item strategy. The package contains functions to wrap high-dimensional data and iterate over them using established R packages for regression modelling (e.g., glmmTMB or mgcv').

The Subsemble algorithm is a general subset ensemble prediction method, which can be used for small, moderate, or large datasets. Subsemble partitions the full dataset into subsets of observations, fits a specified underlying algorithm on each subset, and uses a unique form of k-fold cross-validation to output a prediction function that combines the subset-specific fits. An oracle result provides a theoretical performance guarantee for Subsemble. The paper, "Subsemble: An ensemble method for combining subset-specific algorithm fits" is authored by Stephanie Sapp, Mark J. van der Laan & John Canny (2014) <doi:10.1080/02664763.2013.864263>.

Conduct various tests for evaluating implicit biases in word embeddings: Word Embedding Association Test (Caliskan et al., 2017), <doi:10.1126/science.aal4230>, Relative Norm Distance (Garg et al., 2018), <doi:10.1073/pnas.1720347115>, Mean Average Cosine Similarity (Mazini et al., 2019) <arXiv:1904.04047>, SemAxis (An et al., 2018) <arXiv:1806.05521>, Relative Negative Sentiment Bias (Sweeney & Najafian, 2019) <doi:10.18653/v1/P19-1162>, and Embedding Coherence Test (Dev & Phillips, 2019) <arXiv:1901.07656>.

Fit additive mixed meta-analysis (AMMA) models, extending the mixmeta package <https://cran.r-project.org/package=mixmeta> to allow for spline-based meta-regression. Functions combine features of mgcv <https://cran.r-project.org/package=mgcv> for building spline components and mixmeta for estimating general mixed-effects meta-analysis models.

This package implements a segmentation algorithm for multiple change-point detection in high-dimensional GARCH processes. It simultaneously segments GARCH processes by identifying common change-points, each of which can be shared by a subset or all of the component time series as a change-point in their within-series and/or cross-sectional correlation structure.

This package provides a system contains easy-to-use tools as a support for time series analysis courses. In particular, it incorporates a technique called Generalized Method of Wavelet Moments (GMWM) as well as its robust implementation for fast and robust parameter estimation of time series models which is described, for example, in Guerrier et al. (2013) <doi: 10.1080/01621459.2013.799920>. More details can also be found in the paper linked to via the URL below.

An input controller for R Shiny: a matrix with radio buttons, where only one option per row can be selected.

Renders plots to a temporary image using the ragg graphics device and returns knitr::include_graphics() output. Optionally saves the image to a specified path. This helps ensure consistent appearance across interactive sessions, saved files, and knitted documents. For more details see Pedersen and Shemanarev (2025) <doi: 10.32614/CRAN.package.ragg>.

Computes the Akaike information criterion for the generalized linear models (logistic regression, Poisson regression, and Gaussian graphical models) estimated by the lasso.

Import classification results from the RDP Classifier (Ribosomal Database Project), USEARCH sintax, vsearch sintax and the QIIME2 (Quantitative Insights into Microbial Ecology) classifiers into phyloseq tax_table objects.

Visualizes sulcal morphometry data derived from BrainVisa <https://brainvisa.info/> including width, depth, surface area, and length. The package enables mapping of statistical group results or subject-level values onto cortical surface maps, with options to focus on all sulci or only selected regions of interest. Users can display all four measures simultaneously or restrict plots to chosen measures, creating composite, publication-quality brain visualizations in R to support the analysis and interpretation of sulcal morphology.

Create a hexagon tile map display from spatial polygons. Each polygon is represented by a hexagon tile, placed as close to it's original centroid as possible, with a focus on maintaining spatial relationship to a focal point. Developed to aid visualisation and analysis of spatial distributions across Australia, which can be challenging due to the concentration of the population on the coast and wide open interior.

Companion package to rOpenSci statistical software review project ('rOpenSci authors, 2021; <doi:10.5281/zenodo.5556756>), to facilitate documenting software compliance with statistical standards using Roxygen2 roclets'.

Implement K-nearest neighbor classifier, weighted nearest neighbor classifier, bagged nearest neighbor classifier, optimal weighted nearest neighbor classifier and stabilized nearest neighbor classifier, and perform model selection via 5 fold cross-validation for them. This package also provides functions for computing the classification error and classification instability of a classification procedure.