The Crunch.io service <https://crunch.io/> provides a cloud-based data store and analytic engine, as well as an intuitive web interface. Using this package, analysts can interact with and manipulate Crunch datasets from within R. Importantly, this allows technical researchers to collaborate naturally with team members, managers, and clients who prefer a point-and-click interface.

Package for the analysis of categorical functional data. The main purpose is to compute an encoding (real functional variable) for each state <doi:10.3390/math9233074>. It also provides functions to perform basic statistical analysis on categorical functional data.

Patients Mental Health (MH) status, Substance Use (SU) status, and concurrent MH/SU status in the American/Canadian Healthcare Administrative Databases can be identified. The detection is based on given parameters of interest by clinicians including the list of plausible ICD MH/SU codes (3/4/5 characters), the required number of visits of hospital for MH/SU , the required number of visits of service physicians for MH/SU, and the maximum time span within MH visits, within SU visits, and, between MH and SU visits. Methods are described in: Khan S <https://pubmed.ncbi.nlm.nih.gov/29044442/>, Keen C, et al. (2021) <doi:10.1111/add.15580>, Lavergne MR, et al. (2022) <doi:10.1186/s12913-022-07759-z>, Casillas, S M, et al. (2022) <doi:10.1016/j.abrep.2022.100464>, CIHI (2022) <https://www.cihi.ca/en>, CDC (2024) <https://www.cdc.gov>, WHO (2019) <https://icd.who.int/en>.

Resampling is a standard step in particle filtering and in sequential Monte Carlo. This package implements the chopthin resampler, which keeps a bound on the ratio between the largest and the smallest weights after resampling.

Implement various chromosomal instability metrics. CINmetrics (Chromosomal INstability metrics) provides functions to calculate various chromosomal instability metrics on masked Copy Number Variation(CNV) data at individual sample level. The chromosomal instability metrics have been implemented as described in the following studies: Baumbusch LO et al. 2013 <doi:10.1371/journal.pone.0054356>, Davidson JM et al. 2014 <doi:10.1371/journal.pone.0079079>, Chin SF et al. 2007 <doi:10.1186/gb-2007-8-10-r215>.

This package implements the Bayesian calibration model described in Pratola and Chkrebtii (2018) <DOI:10.5705/ss.202016.0403> for stochastic and deterministic simulators. Additive and multiplicative discrepancy models are currently supported. See <http://www.matthewpratola.com/software> for more information and examples.

Software which provides numerous functionalities for detecting and removing group-level effects from high-dimensional scientific data which, when combined with additional assumptions, allow for causal conclusions, as-described in our manuscripts Bridgeford et al. (2024) <doi:10.1101/2021.09.03.458920> and Bridgeford et al. (2023) <doi:10.48550/arXiv.2307.13868>. Also provides a number of useful utilities for generating simulations and balancing covariates across multiple groups/batches of data via matching and propensity trimming for more than two groups.

Automates the process of containerizing R projects. The core function of containr is generate_dockerfile()', which analyzes an R project's environment and dependencies via an renv lock file and generates a ready-to-use Dockerfile that encapsulates the computational setup. The package helps researchers build portable and consistent workflows so that analyses can be reliably shared, archived, and rerun across systems. See R Core Team (2025) <https://www.R-project.org/>, Ushey et al. (2025) <https://CRAN.R-project.org/package=renv>, and Docker Inc. (2025) <https://www.docker.com/>.

This package provides a dashboard supports the usage of cromwell'. Cromwell is a scientific workflow engine for command line users. This package utilizes cromwell REST APIs and provides these convenient functions: timing diagrams for running workflows, cromwell engine status, a tabular workflow list. For more information about cromwell', visit <http://cromwell.readthedocs.io>.

Generate mean and median weighted or unweighted spatial centers. Functions are analogous to their identically named counterparts within ArcGIS Pro'. Median center methodology based off of Kuhn and Kuenne (1962) <doi:10.1111/j.1467-9787.1962.tb00902.x>.

This package provides the datasets from Efron & Hastie (2016, ISBN: 9781108107952), "Computer Age Statistical Inference: Algorithms, Evidence, and Data Science", in an accessible R format for those who want to use them for study or to try to reproduce analyses from the book.

Data on international and other major cricket matches from ESPNCricinfo <https://www.espncricinfo.com> and Cricsheet <https://cricsheet.org>. This package provides some functions to download the data into tibbles ready for analysis.

This package provides the "comma-free call" operator: %(%'. Use it to call a function without commas between the arguments. Just replace the ( with %(% in a function call, supply your arguments as standard R expressions enclosed by ', and be free of commas (for that call).

This package provides a set of functions for applying a restricted linear algebra to the analysis of count-based data. See the accompanying preprint manuscript: "Normalizing need not be the norm: count-based math for analyzing single-cell data" Church et al (2022) <doi:10.1101/2022.06.01.494334> This tool is specifically designed to analyze count matrices from single cell RNA sequencing assays. The tools implement several count-based approaches for standard steps in single-cell RNA-seq analysis, including scoring genes and cells, comparing cells and clustering, calculating differential gene expression, and several methods for rank reduction. There are many opportunities for further optimization that may prove useful in the analysis of other data. We provide the source code freely available at <https://github.com/shchurch/countland> and encourage users and developers to fork the code for their own purposes.

While data from randomized experiments remain the gold standard for causal inference, estimation of causal estimands from observational data is possible through various confounding adjustment methods. However, the challenge of unmeasured confounding remains a concern in causal inference, where failure to account for unmeasured confounders can lead to biased estimates of causal estimands. Sensitivity analysis within the framework of causal inference can help adjust for possible unmeasured confounding. In `causens`, three main methods are implemented: adjustment via sensitivity functions (Brumback, Hernán, Haneuse, and Robins (2004) <doi:10.1002/sim.1657> and Li, Shen, Wu, and Li (2011) <doi:10.1093/aje/kwr096>), Bayesian parametric modelling and Monte Carlo approaches (McCandless, Lawrence C and Gustafson, Paul (2017) <doi:10.1002/sim.7298>).

Fits hidden Markov models of discrete character evolution which allow different transition rate classes on different portions of a phylogeny. Beaulieu et al (2013) <doi:10.1093/sysbio/syt034>.

Quickly set and summarize contrasts for factors prior to regression analyses. Intended comparisons, baseline conditions, and intercepts can be explicitly set and documented without the user needing to directly manipulate matrices. Reviews and introductions for contrast coding are available in Brehm and Alday (2022)<doi:10.1016/j.jml.2022.104334> and Schad et al. (2020)<doi:10.1016/j.jml.2019.104038>.

The Clinical Trials Network (CTN) of the U.S. National Institute of Drug Abuse sponsored the CTN-0094 research team to harmonize data sets from three nationally-representative clinical trials for opioid use disorder (OUD). The CTN-0094 team herein provides a coded collection of trial outcomes and endpoints used in various OUD clinical trials over the past 50 years. These coded outcome functions are used to contrast and cluster different clinical outcome functions based on daily or weekly patient urine screenings. Note that we abbreviate urine drug screen as "UDS" and urine opioid screen as "UOS". For the example data sets (based on clinical trials data harmonized by the CTN-0094 research team), UDS and UOS are largely interchangeable.

Calculation of distances, shortest paths and isochrones on weighted graphs using several variants of Dijkstra algorithm. Proposed algorithms are unidirectional Dijkstra (Dijkstra, E. W. (1959) <doi:10.1007/BF01386390>), bidirectional Dijkstra (Goldberg, Andrew & Fonseca F. Werneck, Renato (2005) <https://www.cs.princeton.edu/courses/archive/spr06/cos423/Handouts/EPP%20shortest%20path%20algorithms.pdf>), A* search (P. E. Hart, N. J. Nilsson et B. Raphael (1968) <doi:10.1109/TSSC.1968.300136>), new bidirectional A* (Pijls & Post (2009) <https://repub.eur.nl/pub/16100/ei2009-10.pdf>), Contraction hierarchies (R. Geisberger, P. Sanders, D. Schultes and D. Delling (2008) <doi:10.1007/978-3-540-68552-4_24>), PHAST (D. Delling, A.Goldberg, A. Nowatzyk, R. Werneck (2011) <doi:10.1016/j.jpdc.2012.02.007>). Algorithms for solving the traffic assignment problem are All-or-Nothing assignment, Method of Successive Averages, Frank-Wolfe algorithm (M. Fukushima (1984) <doi:10.1016/0191-2615(84)90029-8>), Conjugate and Bi-Conjugate Frank-Wolfe algorithms (M. Mitradjieva, P. O. Lindberg (2012) <doi:10.1287/trsc.1120.0409>), Algorithm-B (R. B. Dial (2006) <doi:10.1016/j.trb.2006.02.008>).

This package provides datasets containing preformatted maps of Norway at the county, municipality, and ward (Oslo only) level for redistricting in 2024, 2020, 2018, and 2017. Multiple layouts are provided (normal, split, and with an insert for Oslo), allowing the user to rapidly create choropleth maps of Norway without any geolibraries.

This package provides color palettes based on crayon colors since the early 1900s. Colors are based on various crayon colors, sets, and promotional palettes, most of which can be found at <https://en.wikipedia.org/wiki/List_of_Crayola_crayon_colors>. All palettes are discrete palettes and are not necessarily color-blind friendly. Provides scales for ggplot2 for discrete coloring.

Every research team have their own script for data management, statistics and most importantly hemodynamic indices. The purpose is to standardize scripts utilized in clinical research. The hemodynamic indices can be used in a long-format dataframe, and add both periods of interest (trigger-periods), and delete artifacts with deleter-files. Transfer function analysis (Claassen et al. (2016) <doi:10.1177/0271678X15626425>) and Mx (Czosnyka et al. (1996) <doi:10.1161/01.str.27.10.1829>) can be calculated using this package.

Dataset containing cumulative COVID-19 deaths (absolute and per 100,000 pop) at the regional level (mostly NUTS 3) for 31 EU/EFTA countries.

Playfair, Four-Square, Scytale, Columnar Transposition and Autokey methods. Further explanation on methods of classical cryptography can be found at Wikipedia; (<https://en.wikipedia.org/wiki/Classical_cipher>).