Solves goal programming problems of the weighted and lexicographic type, as well as combinations of the two, as described by Ignizio (1983) <doi:10.1016/0305-0548(83)90003-5>. Allows for a simple human-readable input describing the problem as a series of equations. Relies on the lpSolve package to solve the underlying linear optimisation problem.

This package implements a one-sector Armington-CES gravity model with general equilibrium (GE) effects. This model is designed to analyze international and domestic trade by capturing the impacts of trade costs and policy changes within a general equilibrium framework. Additionally, it includes a local parameter to run simulations on productivity. The package provides functions for calibration, simulation, and analysis of the model.

This package provides functions are provided for quantifying evolution and selection on complex traits. The package implements effective handling and analysis algorithms scaled for genome-wide data and calculates a composite statistic, denoted Ghat, which is used to test for selection on a trait. The package provides a number of simple examples for handling and analysing the genome data and visualising the output and results. Beissinger et al., (2018) <doi:10.1534/genetics.118.300857>.

This package provides a new take on the bar chart. Similar to a waffle style chart but instead of squares the layout resembles a brick wall.

Estimating trait heritability and handling overfitting. This package includes a collection of functions for (1) estimating genetic variance-covariances and calculate trait heritability; and (2) handling overfitting by calculating the variance components and the heritability through cross validation.

Several Goodness-of-Fit (GoF) tests for Copulae are provided. A new hybrid test, Zhang et al. (2016) <doi:10.1016/j.jeconom.2016.02.017> is implemented which supports all of the individual tests in the package, e.g. Genest et al. (2009) <doi:10.1016/j.insmatheco.2007.10.005>. Estimation methods for the margins are provided and all the tests support parameter estimation and predefined values. The parameters are estimated by pseudo maximum likelihood but if it fails the estimation switches automatically to inversion of Kendall's tau. For reproducibility of results, the functions support the definition of seeds. Also all the tests support automatized parallelization of the bootstrapping tasks. The package provides an interface to perform new GoF tests by submitting the test statistic.

This package provides functions to estimate the parameters of the generalized Poisson distribution with or without covariates using maximum likelihood. The references include Nikoloulopoulos A.K. & Karlis D. (2008). "On modeling count data: a comparison of some well-known discrete distributions". Journal of Statistical Computation and Simulation, 78(3): 437--457, <doi:10.1080/10629360601010760> and Consul P.C. & Famoye F. (1992). "Generalized Poisson regression model". Communications in Statistics - Theory and Methods, 21(1): 89--109, <doi:10.1080/03610929208830766>.

This package provides publication-ready volcano plots for visualizing differential expression results, commonly used in RNA-seq and similar analyses. This tool helps create high-quality visual representations of data using the ggplot2 framework Wickham (2016) <doi:10.1007/978-3-319-24277-4>.

Execute Latent Class Analysis (LCA) and Latent Class Regression (LCR) by using Generalized Structured Component Analysis (GSCA). This is explained in Ryoo, Park, and Kim (2019) <doi:10.1007/s41237-019-00084-6>. It estimates the parameters of latent class prevalence and item response probability in LCA with a single line comment. It also provides graphs of item response probabilities. In addition, the package enables to estimate the relationship between the prevalence and covariates.

Sankey and alluvial diagrams visualise flows of quantities across stages in stacked bars. This package makes it easy to create such diagrams using ggplot2'.

Local structure in genomic data often induces dependence between observations taken at different genomic locations. Ignoring this dependence leads to underestimation of the standard error of parameter estimates. This package uses block bootstrapping to estimate asymptotically correct standard errors of parameters from any standard generalised linear model that may be fit by the glm() function.

This package implements functions and instruments for regression model building and its application to forecasting. The main scope of the package is in variables selection and models specification for cases of time series data. This includes promotional modelling, selection between different dynamic regressions with non-standard distributions of errors, selection based on cross validation, solutions to the fat regression model problem and more. Models developed in the package are tailored specifically for forecasting purposes. So as a results there are several methods that allow producing forecasts from these models and visualising them.

Toolbox for various enrichment analysis methods and quantification of uncertainty of gene sets, Schmid et al. (2016) <doi:10.1093/bioinformatics/btw030>.

This package provides ggplot2 extensions for creating dice-based visualizations where each dot position represents a specific categorical variable. The package includes geom_dice() for displaying presence/absence of categorical variables using traditional dice patterns. Each dice position (1-6) represents a different category, with dots shown only when that category is present. This allows intuitive visualization of up to 6 categorical variables simultaneously.

Two arms clinical trials required sample size is calculated in the comprehensive parametric context. The calculation is based on the type of endpoints(continuous/binary/time-to-event/ordinal), design (parallel/crossover), hypothesis tests (equality/noninferiority/superiority/equivalence), trial arms noncompliance rates and expected loss of follow-up. Methods are described in: Chow SC, Shao J, Wang H, Lokhnygina Y (2017) <doi:10.1201/9781315183084>, Wittes, J (2002) <doi:10.1093/epirev/24.1.39>, Sato, T (2000) <doi:10.1002/1097-0258(20001015)19:19%3C2689::aid-sim555%3E3.0.co;2-0>, Lachin J M, Foulkes, M A (1986) <doi:10.2307/2531201>, Whitehead J(1993) <doi:10.1002/sim.4780122404>, Julious SA (2023) <doi:10.1201/9780429503658>.

Automates the process of adding, committing, and pushing changes to a git repository using commit messages generated by passing the git diff output to the OpenAI GPT-3.5 Turbo model (<https://platform.openai.com/docs/models/gpt-3>).

The algorithm of semi-supervised learning is based on finite Gaussian mixture models and includes a mechanism for handling missing data. It aims to fit a g-class Gaussian mixture model using maximum likelihood. The algorithm treats the labels of unclassified features as missing data, building on the framework introduced by Rubin (1976) <doi:10.2307/2335739> for missing data analysis. By taking into account the dependencies in the missing pattern, the algorithm provides more information for determining the optimal classifier, as specified by Bayes rule.

Forest-based statistical estimation and inference. GRF provides non-parametric methods for heterogeneous treatment effects estimation (optionally using right-censored outcomes, multiple treatment arms or outcomes, or instrumental variables), as well as least-squares regression, quantile regression, and survival regression, all with support for missing covariates.

Data sets used in the book Marra and Radice (2025, ISBN:9781032973111) "Copula Additive Distributional Regression Using R", for illustrating the fitting of various joint (and univariate) regression models, with several types of covariate effects, in the presence of equations errors association.

Ease the transition between R vectors and markdown text. With gluedown and rmarkdown', users can create traditional vectors in R, glue those strings together with the markdown syntax, and print those formatted vectors directly to the document. This package primarily uses GitHub Flavored Markdown (GFM), an offshoot of the unambiguous CommonMark specification by John MacFarlane (2019) <https://spec.commonmark.org/>.

Convert Ensembl gene identifiers from Genotype-Tissue Expression (GTEx) data to identifiers in other annotation systems, including Entrez', HGNC', and UniProt'.

This package implements regression models for bounded continuous data in the open interval (0,1) using the five-parameter Generalized Kumaraswamy distribution. Supports modeling all distribution parameters (alpha, beta, gamma, delta, lambda) as functions of predictors through various link functions. Provides efficient maximum likelihood estimation via Template Model Builder ('TMB'), offering comprehensive diagnostics, model comparison tools, and simulation methods. Particularly useful for analyzing proportions, rates, indices, and other bounded response data with complex distributional features not adequately captured by simpler models.

This package provides a simple way to interact with and extract data from the official Google Knowledge Graph API <https://developers.google.com/knowledge-graph/>.

Maximum likelihood estimation under relational models, with or without the overall effect.