To calculate the sensitivity and specificity in the absence of gold standard using the Bayesian method. The Bayesian method can be referenced at Haiyan Gu and Qiguang Chen (1999) <doi:10.3969/j.issn.1002-3674.1999.04.004>.

Assesses data quality in Observational Medical Outcomes Partnership Common Data Model (OMOP CDM) databases. Executes data quality checks and provides an R `shiny` application to view the results.

Several statistical methods for analyzing survival data under various forms of dependent censoring are implemented in the package. In addition to accounting for dependent censoring, it offers tools to adjust for unmeasured confounding factors. The implemented approaches allow users to estimate the dependency between survival time and dependent censoring time, based solely on observed survival data. For more details on the methods, refer to Deresa and Van Keilegom (2021) <doi:10.1093/biomet/asaa095>, Czado and Van Keilegom (2023) <doi:10.1093/biomet/asac067>, Crommen et al. (2024) <doi:10.1007/s11749-023-00903-9>, Deresa and Van Keilegom (2024) <doi:10.1080/01621459.2022.2161387>, Willems et al. (2025) <doi:10.48550/arXiv.2403.11860>, Ding and Van Keilegom (2025) and D'Haen et al. (2025) <doi:10.1007/s10985-025-09647-0>.

Low level functions for implementing maximum likelihood estimating procedures for complex models using data cloning and Bayesian Markov chain Monte Carlo methods as described in Solymos 2010 <doi:10.32614/RJ-2010-011>. Sequential and parallel MCMC support for JAGS', WinBUGS', OpenBUGS', and Stan'.

Open, read data from and modify Data Packages. Data Packages are an open standard for bundling and describing data sets (<https://datapackage.org>). When data is read from a Data Package care is taken to convert the data as much a possible to R appropriate data types. The package can be extended with plugins for additional data types.

This package provides the user with an interactive application which can be used to facilitate the planning of dose finding studies by applying the theory of optimal experimental design.

Allows humanitarian community, academia, media, government, and non-governmental organizations to utilize the data collected by the Displacement Tracking Matrix (<https://dtm.iom.int>), a unit in the International Organization for Migration. This also provides non-sensitive Internally Displaced Person figures, aggregated at the country, Admin 1 (states, provinces, or equivalent), and Admin 2 (smaller administrative areas) levels.

Fast functions for effective sample size, weighted multivariate mean, variance, and quantile computation, and weight diagnostic plot for generic importance sampling type or other probability weighted samples.

Draws stylized choropleth maps -- hexagonal maps and triangular multiclass hex maps -- for New Zealand District Health Boards and Regional Council areas. These allow faceted, coloured displays of quantitative information for comparison across District Health Boards or Regional Councils. The preprint Lumley (2019) <arXiv:1912.04435> is based on the methods in this package.

This package provides functions for inferring longitudinal dominance hierarchies, which describe dominance relationships and their dynamics in a single latent hierarchy over time. Strauss & Holekamp (in press).

We provide 70 data sets of females of reproductive age from 19 Asian countries, ranging in age from 15 to 49. The data sets are extracted from demographic and health surveys that were conducted over an extended period of time. Moreover, the functions also provide Whippleâ s index as well as age reporting quality such as very rough, rough, approximate, accurate, and highly accurate.

This package provides a framework to help construct R data packages in a reproducible manner. Potentially time consuming processing of raw data sets into analysis ready data sets is done in a reproducible manner and decoupled from the usual R CMD build process so that data sets can be processed into R objects in the data package and the data package can then be shared, built, and installed by others without the need to repeat computationally costly data processing. The package maintains data provenance by turning the data processing scripts into package vignettes, as well as enforcing documentation and version checking of included data objects. Data packages can be version controlled on GitHub', and used to share data for manuscripts, collaboration and reproducible research.

Diffusion Weighted Imaging (DWI) is a Magnetic Resonance Imaging modality, that measures diffusion of water in tissues like the human brain. The package contains R-functions to process diffusion-weighted data. The functionality includes diffusion tensor imaging (DTI), diffusion kurtosis imaging (DKI), modeling for high angular resolution diffusion weighted imaging (HARDI) using Q-ball-reconstruction and tensor mixture models, several methods for structural adaptive smoothing including POAS and msPOAS, and a streamline fiber tracking for tensor and tensor mixture models. The package provides functionality to manipulate and visualize results in 2D and 3D.

Cluster-randomized trials (CRTs) assign treatment to groups rather than individuals, so valid analyses must distinguish cluster-level and individual-level effects and define estimands within a potential-outcomes framework. This package supports right-censored survival outcomes for both single-state (binary) and multi-state settings. For single-state outcomes, it provides estimands based on stage-specific survival contrasts (SPCE) and restricted mean survival time (RMST). For multi-state outcomes, it provides SPCE as well as a generalized win-based restricted mean time-in-favor estimand (RMT-IF). The package implements doubly robust estimators that accommodate covariate-dependent censoring and remain consistent if either the outcome model or the censoring model is correctly specified. Users can choose marginal Cox or gamma-frailty Cox working models for nuisance estimation, and inference is supported via leave-one-cluster-out jackknife variance and confidence interval estimation. Methods are described in Fang et al. (2025) "Estimands and doubly robust estimation for cluster-randomized trials with survival outcomes" <doi:10.48550/arXiv.2510.08438>.

The Dirichlet Laplace shrinkage prior in Bayesian linear regression and variable selection, featuring: utility functions in implementing Dirichlet-Laplace priors such as visualization; scalability in Bayesian linear regression; penalized credible regions for variable selection.

The rapid development of single-cell transcriptomic technologies has helped uncover the cellular heterogeneity within cell populations. However, bulk RNA-seq continues to be the main workhorse for quantifying gene expression levels due to technical simplicity and low cost. To most effectively extract information from bulk data given the new knowledge gained from single-cell methods, we have developed a novel algorithm to estimate the cell-type composition of bulk data from a single-cell RNA-seq-derived cell-type signature. Comparison with existing methods using various real RNA-seq data sets indicates that our new approach is more accurate and comprehensive than previous methods, especially for the estimation of rare cell types. More importantly,our method can detect cell-type composition changes in response to external perturbations, thereby providing a valuable, cost-effective method for dissecting the cell-type-specific effects of drug treatments or condition changes. As such, our method is applicable to a wide range of biological and clinical investigations. Dampened weighted least squares ('DWLS') is an estimation method for gene expression deconvolution, in which the cell-type composition of a bulk RNA-seq data set is computationally inferred. This method corrects common biases towards cell types that are characterized by highly expressed genes and/or are highly prevalent, to provide accurate detection across diverse cell types. See: <https://www.nature.com/articles/s41467-019-10802-z.pdf> for more information about the development of DWLS and the methods behind our functions.

Collects a diverse range of symbolic data and offers a comprehensive set of functions that facilitate the conversion of traditional data into the symbolic data format.

Mechanistically models/predicts the phenology (macro-phases) of 10 crop plants (trained on a big dataset over 80 years derived from the German weather service (DWD) <https://opendata.dwd.de/>). Can be applied for remote sensing purposes, dynamically check the best subset of available covariates for the given dataset and crop.

Likelihood-based inference methods with doubly-truncated data are developed under various models. Nonparametric models are based on Efron and Petrosian (1999) <doi:10.1080/01621459.1999.10474187> and Emura, Konno, and Michimae (2015) <doi:10.1007/s10985-014-9297-5>. Parametric models from the special exponential family (SEF) are based on Hu and Emura (2015) <doi:10.1007/s00180-015-0564-z> and Emura, Hu and Konno (2017) <doi:10.1007/s00362-015-0730-y>. The parametric location-scale models are based on Dorre et al. (2021) <doi:10.1007/s00180-020-01027-6>.

This package provides methods for fitting nonstationary Gaussian process models by spatial deformation, as introduced by Sampson and Guttorp (1992) <doi:10.1080/01621459.1992.10475181>, and by dimension expansion, as introduced by Bornn et al. (2012) <doi:10.1080/01621459.2011.646919>. Low-rank thin-plate regression splines, as developed in Wood, S.N. (2003) <doi:10.1111/1467-9868.00374>, are used to either transform co-ordinates or create new latent dimensions.

Generates simulated data representing the LOX drop testing process (also known as impact testing). A simulated process allows for accelerated study of test behavior. Functions are provided to simulate trials, test series, and groups of test series. Functions for creating plots specific to this process are also included. Test attributes and criteria can be set arbitrarily. This work is not endorsed by or affiliated with NASA. See "ASTM G86-17, Standard Test Method for Determining Ignition Sensitivity of Materials to Mechanical Impact in Ambient Liquid Oxygen and Pressurized Liquid and Gaseous Oxygen Environments" <doi:10.1520/G0086-17>.

Populate data from an R environment into .doc and .docx templates. Create a template document in a program such as Word', and add strings encased in guillemet characters to create flags («example»). Use getDictionary() to create a dictionary of flags and replacement values, then call docket() to generate a populated document.

The function takes a DNA sequence, a start point, an end point in the sequence, dot size and dot color and draws a fractal image of the sequence. The fractal starts in the center of the canvas. The image is drawn by moving base by base along the sequence and dropping a midpoint between the actual point and the corner designated by the actual base. For more details see Jeffrey (1990) <doi:10.1093/nar/18.8.2163>, Hill, Schisler, and Singh (1992) <doi:10.1007/BF00178602>, and Löchel and Heider (2021) <doi:10.1016/j.csbj.2021.11.008>.

Track and document dplyr data pipelines. As you filter, mutate, and join your way through a data set, dtrackr seamlessly keeps track of your data flow and makes publication ready documentation of a data pipeline simple.