Efficient Frequentist profiling and Bayesian marginalization of parameters for which the conditional likelihood is that of a multivariate linear regression model. Arbitrary inter-observation error correlations are supported, with optimized calculations provided for independent-heteroskedastic and stationary dependence structures.

LINCS L1000 is a high-throughput technology that allows the gene expression measurement in a large number of assays. However, to fit the measurements of ~1000 genes in the ~500 color channels of LINCS L1000, every two landmark genes are designed to share a single channel. Thus, a deconvolution step is required to infer the expression values of each gene. Any errors in this step can be propagated adversely to the downstream analyses. We present a LINCS L1000 data peak calling R package l1kdeconv based on a new outlier detection method and an aggregate Gaussian mixture model. Upon the remove of outliers and the borrowing information among similar samples, l1kdeconv shows more stable and better performance than methods commonly used in LINCS L1000 data deconvolution.

This package provides extensions for packages leaflet & mapdeck', many of which are used by package mapview'. Focus is on functionality readily available in Geographic Information Systems such as Quantum GIS'. Includes functions to display coordinates of mouse pointer position, query image values via mouse pointer and zoom-to-layer buttons. Additionally, provides a feature type agnostic function to add points, lines, polygons to a map.

This package provides a bootstrap proportion test for Brand Lift Testing to quantify the effectiveness of online advertising. Methods of the bootstrap proportion test are presented in Liu, Yu, Mao, Wu, Dyer (2023) <doi:10.1145/3583780.3615021>.

Given independent and identically distributed observations X(1), ..., X(n), allows to compute the maximum likelihood estimator (MLE) of probability mass function (pmf) under the assumption that it is log-concave, see Weyermann (2007) and Balabdaoui, Jankowski, Rufibach, and Pavlides (2012). The main functions of the package are logConDiscrMLE that allows computation of the log-concave MLE, logConDiscrCI that computes pointwise confidence bands for the MLE, and kInflatedLogConDiscr that computes a mixture of a log-concave PMF and a point mass at k.

Due to lack of proper inference procedure and software, the ordinary linear regression model is seldom used in practice for the analysis of right censored data. This paper presents an S-Plus/R program that implements a recently developed inference procedure (Jin, Lin and Ying, 2006) <doi:10.1093/biomet/93.1.147> for the accelerated failure time model based on the least-squares principle.

This package provides functions for regional frequency analysis using the methods of J. R. M. Hosking and J. R. Wallis (1997), "Regional frequency analysis: an approach based on L-moments".

Allows you to read and change the state of LIFX smart light bulbs via the LIFX developer api <https://api.developer.lifx.com/>. Covers most LIFX api endpoints, including changing light color and brightness, selecting lights by id, group or location as well as activating effects.

This package provides methods for estimating borders of uniform distribution on the interval (one-dimensional) and on the elliptical domain (two-dimensional) under measurement errors. For one-dimensional case, it also estimates the length of underlying uniform domain and tests the hypothesized length against two-sided or one-sided alternatives. For two-dimensional case, it estimates the area of underlying uniform domain. It works with numerical inputs as well as with pictures in JPG format.

Linear dimension reduction subspaces can be uniquely defined using orthogonal projection matrices. This package provides tools to compute distances between such subspaces and to compute the average subspace. For details see Liski, E.Nordhausen K., Oja H., Ruiz-Gazen A. (2016) Combining Linear Dimension Reduction Subspaces <doi:10.1007/978-81-322-3643-6_7>.

Converts table-like objects to stand-alone PDF or PNG. Can be used to embed tables and arbitrary content in PDF or Word documents. Provides a low-level R interface for creating LaTeX code, e.g. command() and a high-level interface for creating PDF documents, e.g. as.pdf.data.frame(). Extensive customization is available via mid-level functions, e.g. as.tabular(). See also package?latexpdf'. Support for PNG is experimental; see as.png.data.frame'. Adapted from metrumrg <https://r-forge.r-project.org/R/?group_id=1215>. Requires a compatible installation of pdflatex', e.g. <https://miktex.org/>.

Solves quadratic programming problems where the Hessian is represented as the product of two matrices. Thanks to Greg Hunt for helping getting this version back on CRAN. The methods in this package are described in: Ormerod, Wand and Koch (2008) "Penalised spline support vector classifiers: computational issues" <doi:10.1007/s00180-007-0102-8>.

Select statistically similar research groups by backward selection using various robust algorithms, including a heuristic based on linear discriminant analysis, multiple heuristics based on the test statistic, and parallelized exhaustive search.

Fits semi-confirmatory structural equation modeling (SEM) via penalized likelihood (PL) or penalized least squares (PLS). For details, please see Huang (2020) <doi:10.18637/jss.v093.i07>.

This package provides easy access for sentiment lexicons for those who want to do text analysis in Portuguese texts. As of now, two Portuguese lexicons are available: SentiLex-PT02 and OpLexicon (v2.1 and v3.0).

Auxiliary package for better/faster analytics, visualization, data mining, and machine learning tasks. With a wide variety of family functions, like Machine Learning, Data Wrangling, Marketing Mix Modeling (Robyn), Exploratory, API, and Scrapper, it helps the analyst or data scientist to get quick and robust results, without the need of repetitive coding or advanced R programming skills.

This package provides a fast generalized edit distance and string alignment computation mainly for linguistic aims. As a generalization to the classic edit distance algorithms, the package allows users to define custom cost for every symbol's insertion, deletion, and substitution. The package also allows character combinations in any length to be seen as a single symbol which is very useful for International Phonetic Alphabet (IPA) transcriptions with diacritics. In addition to edit distance result, users can get detailed alignment information such as all possible alignment scenarios between two strings which is useful for testing, illustration or any further usage. Either the distance matrix or its long table form can be obtained and tools to do such conversions are provided. All functions in the package are implemented in C++ and the distance matrix computation is parallelized leveraging the RcppThread package.

This package implements a logistic box-cox model. This model is fully described in Xing, L. et al. (2021) <doi:10.1002/cjs.11587>.

This package implements tree-based methods for longitudinal data. The package constructs decision trees that evaluate both the main effect of a covariate and its interaction with time through a weighted splitting criterion. It supports single-tree construction, bootstrap-based multiple-tree selection, and tree visualisation. For methodological details, see Obata and Sugimoto (2026) <doi:10.1007/s11634-025-00665-2>.

This package provides a comprehensive toolkit for the analysis of longitudinal integration site data, including data cleaning, quality control, statistical modeling, and visualization. It streamlines the entire workflow of integration site analysis, supports simple input formats, and provides user-friendly functions for researchers in virus integration site analysis. Ni et al. (2025) <doi:10.64898/2025.12.20.695672>.

This package provides utilities to detect common data leakage patterns including train/test contamination, temporal leakage, and data duplication, enhancing model reliability and reproducibility in machine learning workflows. Generates diagnostic reports and visual summaries to support data validation. Methods based on best practices from Hastie, Tibshirani, and Friedman (2009, ISBN:978-0387848570).

Computes the probability density function, the cumulative distribution function, the hazard rate function, the quantile function and random generation for Lindley Power Series distributions, see Nadarajah and Si (2018) <doi:10.1007/s13171-018-0150-x>.

The leaflet JavaScript library provides many plugins some of which are available in the core leaflet package, but there are many more. It is not possible to support them all in the core leaflet package. This package serves as an add-on to the leaflet package by providing extra functionality via leaflet plugins.

We developed an approach to detect differential expression features in long non-coding RNA low counts, using generalized linear model with zero-inflated exponential quasi likelihood ratio test. Methods implemented in this package are described in Li (2019) <doi:10.1186/s12864-019-5926-4>.