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Genomic alterations including single nucleotide substitution, copy number alteration, etc. are the major force for cancer initialization and development. Due to the specificity of molecular lesions caused by genomic alterations, we can generate characteristic alteration spectra, called signature (Wang, Shixiang, et al. (2021) <DOI:10.1371/journal.pgen.1009557> & Alexandrov, Ludmil B., et al. (2020) <DOI:10.1038/s41586-020-1943-3> & Steele Christopher D., et al. (2022) <DOI:10.1038/s41586-022-04738-6>). This package helps users to extract, analyze and visualize signatures from genomic alteration records, thus providing new insight into cancer study.
This package provides you with easy, programmatic access to SRDP data.
Powerful graphical displays and statistical tools for structured problem solving and diagnosis. The functions of the sherlock package are especially useful for applying the process of elimination as a problem diagnosis technique. The sherlock package was designed to seamlessly work with the tidyverse set of packages and provides a collection of graphical displays built on top of the ggplot and plotly packages, such as different kinds of small multiple plots as well as helper functions such as adding reference lines, normalizing observations, reading in data or saving analysis results in an Excel file. References: David Hartshorne (2019, ISBN: 978-1-5272-5139-7). Stefan H. Steiner, R. Jock MacKay (2005, ISBN: 0873896467).
Supplementary functions for item response models aiming to complement existing R packages. The functionality includes among others multidimensional compensatory and noncompensatory IRT models (Reckase, 2009, <doi:10.1007/978-0-387-89976-3>), MCMC for hierarchical IRT models and testlet models (Fox, 2010, <doi:10.1007/978-1-4419-0742-4>), NOHARM (McDonald, 1982, <doi:10.1177/014662168200600402>), Rasch copula model (Braeken, 2011, <doi:10.1007/s11336-010-9190-4>; Schroeders, Robitzsch & Schipolowski, 2014, <doi:10.1111/jedm.12054>), faceted and hierarchical rater models (DeCarlo, Kim & Johnson, 2011, <doi:10.1111/j.1745-3984.2011.00143.x>), ordinal IRT model (ISOP; Scheiblechner, 1995, <doi:10.1007/BF02301417>), DETECT statistic (Stout, Habing, Douglas & Kim, 1996, <doi:10.1177/014662169602000403>), local structural equation modeling (LSEM; Hildebrandt, Luedtke, Robitzsch, Sommer & Wilhelm, 2016, <doi:10.1080/00273171.2016.1142856>).
Computes the entire solution paths for Support Vector Regression(SVR) with respect to the regularization parameter, lambda and epsilon in epsilon-intensive loss function, efficiently. We call each path algorithm svrpath and epspath. See Wang, G. et al (2008) <doi:10.1109/TNN.2008.2002077> for details regarding the method.
Ozone, NOx (= Sum of nitrogen monoxide and nitrogen dioxide), nitrogen monoxide, ambient temperature, dew point, wind speed and wind direction at 3 sites around lake of Lucerne in Central Switzerland in 30 min time resolution for year 2004.
Computes the sit coefficient between two vectors x and y, possibly all paired coefficients for a matrix. The reference for the methods implemented here is Zhang, Yilin, Canyi Chen, and Liping Zhu. 2022. "Sliced Independence Test." Statistica Sinica. <doi:10.5705/ss.202021.0203>. This package incorporates the Galton peas example.
Use piping, verbs like group_by and summarize', and other dplyr inspired syntactic style when calculating summary statistics on survey data using functions from the survey package.
This package provides a collection of tools to access prepared air quality monitoring data files from web servers with ease and speed. Air quality data are sourced from open and publicly accessible repositories and can be found in these locations: <https://www.eea.europa.eu/data-and-maps/data/airbase-the-european-air-quality-database-8> and <https://discomap.eea.europa.eu/map/fme/AirQualityExportAirbase.htm>. The web server space has been provided by Ricardo Energy & Environment.
This package provides developer-focused helper functions and S3 classes to ease the creation of structured subtypes of data frames. Developers can require certain columns and types to be present, and can enforce crossing and nesting relationships between values in different columns. Type-specific metadata and attributes are preserved through common data frame manipulations.
Health research using data from electronic health records (EHR) has gained popularity, but misclassification of EHR-derived disease status and lack of representativeness of the study sample can result in substantial bias in effect estimates and can impact power and type I error for association tests. Here, the assumed target of inference is the relationship between binary disease status and predictors modeled using a logistic regression model. SAMBA implements several methods for obtaining bias-corrected point estimates along with valid standard errors as proposed in Beesley and Mukherjee (2020) <doi:10.1111/biom.13400>, Biometrics.
This package performs predictions of totals and weighted sums, or finite population block kriging, on spatial data using the methods in Ver Hoef (2008) <doi:10.1007/s10651-007-0035-y>. The primary outputs are an estimate of the total, mean, or weighted sum in the region, an estimated prediction variance, and a plot of the predicted and observed values. This is useful primarily to users with ecological data that are counts or densities measured on some sites in a finite area of interest. Spatial prediction for the total count or average density in the entire region can then be done using the functions in this package.
This package provides shiny components styled using the GOV.UK Design System. See <https://design-system.service.gov.uk/components/> for component guidance.
This package provides functions to speed up the exploratory analysis of simple datasets using dplyr'. Functions are provided to do the common tasks of calculating confidence intervals.
These are my collection of R Markdown templates, mostly for compilation to PDF. These are useful for all things academic and professional, if you are using R Markdown for things like your CV or your articles and manuscripts.
Practitioners of Bayesian statistics often use Markov chain Monte Carlo (MCMC) samplers to sample from a posterior distribution. This package determines whether the MCMC sample is large enough to yield reliable estimates of the target distribution. In particular, this calculates a Gelman-Rubin convergence diagnostic using stable and consistent estimators of Monte Carlo variance. Additionally, this uses the connection between an MCMC sample's effective sample size and the Gelman-Rubin diagnostic to produce a threshold for terminating MCMC simulation. Finally, this informs the user whether enough samples have been collected and (if necessary) estimates the number of samples needed for a desired level of accuracy. The theory underlying these methods can be found in "Revisiting the Gelman-Rubin Diagnostic" by Vats and Knudson (2018) <arXiv:1812:09384>.
The Brazilian system for diploma registration and validation on technical and superior courses are managing by Sistec platform, see <https://sistec.mec.gov.br/>. This package provides tools for Brazilian institutions to update the student's registration and make data analysis about their situation, retention and drop out.
This package provides a set of plotting methods for simmer trajectories and simulations.
This package provides SAS'-style IF/ELSE chains, independent IF rules, and DELETE logic for data.table', enabling clinical programmers to express Study Data Tabulation Model (SDTM) and Analysis Data Model (ADaM)-style derivations in familiar SAS-like syntax. Methods are informed by clinical data standards described in CDISC SDTM and ADaM implementation guides. See <https://www.cdisc.org/standards/foundational/sdtm> and <https://www.cdisc.org/standards/foundational/adam>.
Capture screenshots in Shiny applications. Screenshots can either be of the entire viewable page, or a specific section of the page. The captured image is automatically downloaded as a PNG image, or it can also be saved on the server. Powered by the html2canvas JavaScript library.
Fits spatial mixture models, including spatial Gaussian mixtures and mixtures of spatial factor analyzers, to complete or incomplete data. Spatial decay can be represented by monotone I-splines or a normalized sigmoid. Missing entries are handled using a built-in partial expectation-maximization procedure for matrix-variate data. The spatial covariance and spatial factor analyzer models are described in Lu and colleagues (2026a) "Spatial Covariance Constraints for Gaussian Mixture Models" <doi:10.48550/arXiv.2601.07979> and Lu and colleagues (2026b) "Mixtures of spatial factor analyzers for tensor-variate data" <doi:10.48550/arXiv.2607.07887>.
This package provides a rich set of UI components for building Shiny applications, including inputs, containers, overlays, menus, and various utilities. All components from Fluent UI (the underlying JavaScript library) are available and have usage examples in R.
This package provides a set of functions to calculate sample size for two-sample difference in means tests. Does adjustments for either nonadherence or variability that comes from using data to estimate parameters.
This package provides a fast, consistent tool for plotting and facilitating the analysis of stratigraphic and sedimentological data. Taking advantage of the flexible plotting tools available in R, SDAR uses stratigraphic and sedimentological data to produce detailed graphic logs for outcrop sections and borehole logs. These logs can include multiple features (e.g., bed thickness, lithology, samples, sedimentary structures, colors, fossil content, bioturbation index, gamma ray logs) (Johnson, 1992, <ISSN 0037-0738>).