To decompose symmetric matrices such as brain connectivity matrices so that one can extract sparse latent component matrices and also estimate mixing coefficients, a blind source separation (BSS) method named LOCUS was proposed in Wang and Guo (2023) <arXiv:2008.08915>. For brain connectivity matrices, the outputs correspond to sparse latent connectivity traits and individual-level trait loadings.

Automated analysis and modeling of longitudinal omics data (e.g. breath metabolomics') using generalized spline mixed effect models. Including automated filtering of noise parameters and determination of breakpoints.

Regression analysis of mixed sparse synchronous and asynchronous longitudinal covariates. Please cite the manuscripts corresponding to this package: Sun, Z. et al. (2023) <arXiv:2305.17715> and Liu, C. et al. (2023) <arXiv:2305.17662>.

Implementation based on Zhang, Jie & Huang, Kun (2014) <doi:10.4137/CIN.S14021> Normalized ImQCM: An Algorithm for Detecting Weak Quasi-Cliques in Weighted Graph with Applications in Gene Co-Expression Module Discovery in Cancers. Cancer informatics, 13, CIN-S14021.

This package provides string similarity calculations inspired by the Python thefuzz package. Compare strings by edit distance, similarity ratio, best matching substring, ordered token matching and set-based token matching. A range of edit distance measures are available thanks to the stringdist package.

Efficient procedures for fitting the regularization path for linear, binomial, multinomial, Ising and Potts models with lasso, group lasso or column lasso(only for multinomial) penalty. The package uses Linearized Bregman Algorithm to solve the regularization path through iterations. Bregman Inverse Scale Space Differential Inclusion solver is also provided for linear model with lasso penalty.

This package provides a LaTeX Letter class for rmarkdown', using the pandoc-letter template adapted for use with markdown'.

Conducts a cointegration test for high-dimensional vector autoregressions (VARs) of order k based on the large N,T asymptotics of Bykhovskaya and Gorin, 2022 (<doi:10.48550/arXiv.2202.07150>). The implemented test is a modification of the Johansen likelihood ratio test. In the absence of cointegration the test converges to the partial sum of the Airy-1 point process. This package contains simulated quantiles of the first ten partial sums of the Airy-1 point process that are precise up to the first three digits.

Life and Fertility Tables are appropriate to study the dynamics of arthropods populations. This package provides utilities for constructing Life Tables and Fertility Tables, related demographic parameters, and some simple graphs of interest. It also offers functions to transform the obtained data into a known format for better manipulation. In addition, two methods for obtaining the confidence interval are included.

Lexical response data is a package that can be used for processing cued-recall, free-recall, and sentence responses from memory experiments.

Client for programmatic access to the Lake Multi-scaled Geospatial and Temporal database <https://lagoslakes.org>, with functions for accessing lake water quality and ecological context data for the US.

This package provides functions to simulate data from large-scale educational assessments, including background questionnaire data and cognitive item responses that adhere to a multiple-matrix sampled design. The theoretical foundation can be found on Matta, T.H., Rutkowski, L., Rutkowski, D. et al. (2018) <doi:10.1186/s40536-018-0068-8>.

Conducts various numerical analyses and simulations in population genetics and evolutionary theory, primarily for the purpose of teaching (and learning about) key concepts in population & quantitative genetics, and evolutionary theory.

Fits a linear excess relative risk model by maximum likelihood, possibly including several variables and allowing for lagged exposures.

Without imposing stringent distributional assumptions or shape restrictions, nonparametric estimation has been popular in economics and other social sciences for counterfactual analysis, program evaluation, and policy recommendations. This package implements a novel density (and derivatives) estimator based on local polynomial regressions, documented in Cattaneo, Jansson and Ma (2022) <doi:10.18637/jss.v101.i02>: lpdensity() to construct local polynomial based density (and derivatives) estimator, and lpbwdensity() to perform data-driven bandwidth selection.

Classical tests of goodness-of-fit aim to validate the conformity of a postulated model to the data under study. In their standard formulation, however, they do not allow exploring how the hypothesized model deviates from the truth nor do they provide any insight into how the rejected model could be improved to better fit the data. To overcome these shortcomings, we establish a comprehensive framework for goodness-of-fit which naturally integrates modeling, estimation, inference and graphics. In this package, the deviance tests and comparison density plots are performed to conduct the LP smoothed inference, where the letter L denotes nonparametric methods based on quantiles and P stands for polynomials. Simulations methods are used to perform variance estimation, inference and post-selection adjustments. Algeri S. and Zhang X. (2020) <arXiv:2005.13011>.

This package contains data sets to accompany the book: Lazic SE (2016). "Experimental Design for Laboratory Biologists: Maximising Information and Improving Reproducibility". Cambridge University Press.

Constructs genotype x environment interaction (GxE) models where G is a weighted sum of genetic variants (genetic score) and E is a weighted sum of environments (environmental score) using the alternating optimization algorithm by Jolicoeur-Martineau et al. (2017) <arXiv:1703.08111>. This approach has greatly enhanced predictive power over traditional GxE models which include only a single genetic variant and a single environmental exposure. Although this approach was originally made for GxE modelling, it is flexible and does not require the use of genetic and environmental variables. It can also handle more than 2 latent variables (rather than just G and E) and 3-way interactions or more. The LEGIT model produces highly interpretable results and is very parameter-efficient thus it can even be used with small sample sizes (n < 250). Tools to determine the type of interaction (vantage sensitivity, diathesis-stress or differential susceptibility), with any number of genetic variants or environments, are available <arXiv:1712.04058>. The software can now produce mixed-effects LEGIT models through the lme4 package.

Crabs in the English channel, deer skulls, English monarchs, half-caste Manga characters, Jamaican cities, Shakespeare's The Tempest, drugged up cyclists and sexually transmitted diseases.

This package provides extensions to the leaflet package to customize legends with images, text styling, orientation, sizing, and symbology and functions to create symbols to plot on maps.

Analysis, imputation, and multiple imputation of count data using covariates. LORI uses a log-linear Poisson model where main row and column effects, as well as effects of known covariates and interaction terms can be fitted. The estimation procedure is based on the convex optimization of the Poisson loss penalized by a Lasso type penalty and a nuclear norm. LORI returns estimates of main effects, covariate effects and interactions, as well as an imputed count table. The package also contains a multiple imputation procedure. The methods are described in Robin, Josse, Moulines and Sardy (2019) <doi:10.1016/j.jmva.2019.04.004>.

Given a postulated model and a set of data, the comparison density is estimated and the deviance test is implemented in order to assess if the data distribution deviates significantly from the postulated model. Finally, the results are summarized in a CD-plot as described in Algeri S. (2019) <arXiv:1906.06615>.

This package provides a bridge between the loon and ggplot2 packages. Extends the grammar of ggplot to add clauses to create interactive loon plots. Existing ggplot(s) can be turned into interactive loon plots and loon plots into static ggplot(s); the function loon.ggplot() is the bridge from one plot structure to the other.

Various efficient and robust bootstrap methods are implemented for linear models with least squares estimation. Functions within this package allow users to create bootstrap sampling distributions for model parameters, test hypotheses about parameters, and visualize the bootstrap sampling or null distributions. Methods implemented for linear models include the wild bootstrap by Wu (1986) <doi:10.1214/aos/1176350142>, the residual and paired bootstraps by Efron (1979, ISBN:978-1-4612-4380-9), the delete-1 jackknife by Quenouille (1956) <doi:10.2307/2332914>, and the Bayesian bootstrap by Rubin (1981) <doi:10.1214/aos/1176345338>.