This package provides a tool which allows users the ability to intuitively create flexible, reproducible portable document format reports comprised of aesthetically pleasing tables, images, plots and/or text.

Allows the user to animate text within rmarkdown documents and shiny applications. The animations are activated using the Animate.css library. See <https://animate.style/> for more information.

This package provides a gradient descent algorithm to find a geodesic relationship between real-valued independent variables and a manifold-valued dependent variable (i.e. geodesic regression). Available manifolds are Euclidean space, the sphere, hyperbolic space, and Kendall's 2-dimensional shape space. Besides the standard least-squares loss, the least absolute deviations, Huber, and Tukey biweight loss functions can also be used to perform robust geodesic regression. Functions to help choose appropriate cutoff parameters to maintain high efficiency for the Huber and Tukey biweight estimators are included, as are functions for generating random tangent vectors from the Riemannian normal distributions on the sphere and hyperbolic space. The n-sphere is a n-dimensional manifold: we represent it as a sphere of radius 1 and center 0 embedded in (n+1)-dimensional space. Using the hyperboloid model of hyperbolic space, n-dimensional hyperbolic space is embedded in (n+1)-dimensional Minkowski space as the upper sheet of a hyperboloid of two sheets. Kendall's 2D shape space with K landmarks is of real dimension 2K-4; preshapes are represented as complex K-vectors with mean 0 and magnitude 1. Details are described in Shin, H.-Y. and Oh, H.-S. (2020) <arXiv:2007.04518>. Also see Fletcher, P. T. (2013) <doi:10.1007/s11263-012-0591-y>.

This package provides a network-based gene weighting algorithm for pathway enrichment analysis, using either RNA-seq or microarray data. Zhaoyuan Fang, Weidong Tian and Hongbin Ji (2012) <doi:10.1038/cr.2011.149>.

Given a landscape resistance surface, creates minimum planar graph (Fall et al. (2007) <doi:10.1007/s10021-007-9038-7>) and grains of connectivity (Galpern et al. (2012) <doi:10.1111/j.1365-294X.2012.05677.x>) models that can be used to calculate effective distances for landscape connectivity at multiple scales. Documentation is provided by several vignettes, and a paper (Chubaty, Galpern & Doctolero (2020) <doi:10.1111/2041-210X.13350>).

Robust multiple or multivariate linear regression, nonparametric regression on orthogonal components, classical or robust partial least squares models as described in Bilodeau, Lafaye De Micheaux and Mahdi (2015) <doi:10.18637/jss.v065.i01>.

Cross validation informed Relaxed LASSO (or more generally elastic net), gradient boosting machine ('xgboost'), Random Forest ('RandomForestSRC'), Oblique Random Forest ('aorsf'), Artificial Neural Network (ANN), Recursive Partitioning ('RPART') or step wise regression models are fit. Cross validation leave out samples (leading to nested cross validation) or bootstrap out-of-bag samples are used to evaluate and compare performances between these models with results presented in tabular or graphical means. Calibration plots can also be generated, again based upon (outer nested) cross validation or bootstrap leave out (out of bag) samples. For some datasets, for example when the design matrix is not of full rank, glmnet may have very long run times when fitting the relaxed lasso model, from our experience when fitting Cox models on data with many predictors and many patients, making it difficult to get solutions from either glmnet() or cv.glmnet(). This may be remedied by using the path=TRUE option when calling glmnet() and cv.glmnet(). Within the glmnetr package the approach of path=TRUE is taken by default. other packages doing similar include nestedcv <https://cran.r-project.org/package=nestedcv>, glmnetSE <https://cran.r-project.org/package=glmnetSE> which may provide different functionality when performing a nested CV. Use of the glmnetr has many similarities to the glmnet package and it could be helpful for the user of glmnetr also become familiar with the glmnet package <https://cran.r-project.org/package=glmnet>, with the "An Introduction to glmnet'" and "The Relaxed Lasso" being especially useful in this regard.

Offers a generalization of the scatterplot matrix based on the recognition that most datasets include both categorical and quantitative information. Traditional grids of scatterplots often obscure important features of the data when one or more variables are categorical but coded as numerical. The generalized pairs plot offers a range of displays of paired combinations of categorical and quantitative variables. Emerson et al. (2013) <DOI:10.1080/10618600.2012.694762>.

Simulation and analysis of graded response data with different types of estimators. Also, an interactive shiny application is provided with graphics for characteristic and information curves. Samejima (2018) <doi:10.1007/978-1-4757-2691-6_5>.

Generic Machine Learning Inference on heterogeneous treatment effects in randomized experiments as proposed in Chernozhukov, Demirer, Duflo and Fernández-Val (2020) <arXiv:1712.04802>. This package's workhorse is the mlr3 framework of Lang et al. (2019) <doi:10.21105/joss.01903>, which enables the specification of a wide variety of machine learners. The main functionality, GenericML(), runs Algorithm 1 in Chernozhukov, Demirer, Duflo and Fernández-Val (2020) <arXiv:1712.04802> for a suite of user-specified machine learners. All steps in the algorithm are customizable via setup functions. Methods for printing and plotting are available for objects returned by GenericML(). Parallel computing is supported.

This package provides functions to assess the goodness of fit of binary, multinomial and ordinal logistic models. Included are the Hosmer-Lemeshow tests (binary, multinomial and ordinal) and the Lipsitz and Pulkstenis-Robinson tests (ordinal).

Robust Estimation of Multivariate Location and Scatter in the Presence of Cellwise and Casewise Contamination and Missing Data.

Symbolic calculation (addition or multiplication) and evaluation of multivariate polynomials with rational coefficients.

An interface for fitting generalized additive models (GAMs) and generalized additive mixed models (GAMMs) using the lme4 package as the computational engine, as described in Helwig (2024) <doi:10.3390/stats7010003>. Supports default and formula methods for model specification, additive and tensor product splines for capturing nonlinear effects, and automatic determination of spline type based on the class of each predictor. Includes an S3 plot method for visualizing the (nonlinear) model terms, an S3 predict method for forming predictions from a fit model, and an S3 summary method for conducting significance testing using the Bayesian interpretation of a smoothing spline.

Performing goodness-of-fit tests for stochastic block models used to fit network data. Among the three variants discussed in Karwa et al. (2023) <doi:10.1093/jrsssb/qkad084>, goodness-of-fit test has been performed for the Erdos-Renyi (ER) and Beta versions.

Enhance a mice imputation workflow with visualizations for incomplete and/or imputed data. The plotting functions produce ggplot objects which may be easily manipulated or extended. Use ggmice to inspect missing data, develop imputation models, evaluate algorithmic convergence, or compare observed versus imputed data.

This package implements common geostatistical methods in a clean, straightforward, efficient manner. The methods are discussed in Schabenberger and Gotway (2004, <ISBN:9781584883227>) and Waller and Gotway (2004, <ISBN:9780471387718>).

Help to the occasional R user for synthesis and enhanced graphical visualization of redundancy analysis (RDA) and principal component analysis (PCA) methods and objects. Inputs are : data frame, RDA (package vegan') and PCA (package FactoMineR') objects. Outputs are : synthesized results of RDA, displayed in console and saved in tables ; displayed and saved objects of PCA graphic visualization of individuals and variables projections with multiple graphic parameters.

Evaluates likelihood ratio tests for alleged ancestry. Implements the methods of Tvedebrink et al (2018) <doi:10.1016/j.tpb.2017.12.004>.

Solves goal programming problems of the weighted and lexicographic type, as well as combinations of the two, as described by Ignizio (1983) <doi:10.1016/0305-0548(83)90003-5>. Allows for a simple human-readable input describing the problem as a series of equations. Relies on the lpSolve package to solve the underlying linear optimisation problem.

This package performs linear regression with correlated predictors, responses and correlated measurement errors in predictors and responses, correcting for biased caused by these.

Wrapper around geom_histogram() of ggplot2 to plot the histogram of a numeric vector. This is especially useful, since qplot() was deprecated in ggplot2 3.4.0.

This package provides a Gibbs sampler corresponding to a Group Inverse-Gamma Gamma (GIGG) regression model with adjustment covariates. Hyperparameters in the GIGG prior specification can either be fixed by the user or can be estimated via Marginal Maximum Likelihood Estimation. Jonathan Boss, Jyotishka Datta, Xin Wang, Sung Kyun Park, Jian Kang, Bhramar Mukherjee (2021) <arXiv:2102.10670>.

This package provides a novel PRS model is introduced to enhance the prediction accuracy by utilising GxE effects. This package performs Genome Wide Association Studies (GWAS) and Genome Wide Environment Interaction Studies (GWEIS) using a discovery dataset. The package has the ability to obtain polygenic risk scores (PRSs) for a target sample. Finally it predicts the risk values of each individual in the target sample. Users have the choice of using existing models (Li et al., 2015) <doi:10.1093/annonc/mdu565>, (Pandis et al., 2013) <doi:10.1093/ejo/cjt054>, (Peyrot et al., 2018) <doi:10.1016/j.biopsych.2017.09.009> and (Song et al., 2022) <doi:10.1038/s41467-022-32407-9>, as well as newly proposed models for genomic risk prediction (refer to the URL for more details).