Computes confidence intervals for the positive predictive value (PPV) and negative predictive value (NPV) based on varied scenarios. In situations where the proportion of diseased subjects does not correspond to the disease prevalence (e.g. case-control studies), this package provides two types of solutions: 1) five methods for estimating confidence intervals for PPV and NPV via ratio of two binomial proportions including Gart & Nam (1988), Walter (1975), MOVER-J (Laud, 2017), Fieller (1954), and Bootstrap (Efron, 1979); 2) three direct methods that compute the confidence intervals including Pepe (2003), Zhou (2007), and Delta. In prospective studies where the proportion of diseased subjects is an unbiased estimate of the disease prevalence, this package provides several methods for calculating the confidence intervals for PPV and NPV including Clopper-Pearson, Wald, Wilson, Agresti-Coull, and Beta. See the Details and References sections in the corresponding functions.

OpenAI's ChatGPT <https://chat.openai.com/> coding assistant for RStudio'. A set of functions and RStudio addins that aim to help the R developer in tedious coding tasks.

This package performs analysis of complex dynamic systems with a focus on the temporal unfolding of patterns, changes, and state transitions in behavioral data. Supports both time series and sequence data and provides tools for the analysis and visualization of complexity, pattern identification, trends, regimes, sequence typology as well as early warning signals.

Estimation, prediction, and simulation of nonstationary Gaussian process with modular covariate-based covariance functions. Sources of nonstationarity, such as spatial mean, variance, geometric anisotropy, smoothness, and nugget, can be considered based on spatial characteristics. An induced compact-supported nonstationary covariance function is provided, enabling fast and memory-efficient computations when handling densely sampled domains.

Calculations of "EP15-A3 document. A manual for user verification of precision and estimation of bias" CLSI (2014, ISBN:1-56238-966-1).

This data package contains monthly climate data in Germany, it can be used for heating and cooling calculations (external temperature, heating / cooling days, solar radiation).

An interactive document on the topic of confusion matrix analysis using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://predanalyticssessions1.shinyapps.io/ConfusionMatrixShiny/>.

This package provides tools to process CBASS-derived PAM data efficiently. Minimal requirements are PAM-based photosynthetic efficiency data (or data from any other continuous variable that changes with temperature, e.g. relative bleaching scores) from 4 coral samples (nubbins) subjected to 4 temperature profiles of at least 2 colonies from 1 coral species from 1 site. Please refer to the following CBASS (Coral Bleaching Automated Stress System) papers for in-depth information regarding CBASS acute thermal stress assays, experimental design considerations, and ED5/ED50/ED95 thermal parameters: Nicolas R. Evensen et al. (2023) <doi:10.1002/lom3.10555> Christian R. Voolstra et al. (2020) <doi:10.1111/gcb.15148> Christian R. Voolstra et al. (2025) <doi:10.1146/annurev-marine-032223-024511>.

This package provides functions for performing experimental comparisons of algorithms using adequate sample sizes for power and accuracy. Implements the methodology originally presented in Campelo and Takahashi (2019) <doi:10.1007/s10732-018-9396-7> for the comparison of two algorithms, and later generalised in Campelo and Wanner (Submitted, 2019) <arxiv:1908.01720>.

Calculate the likelihood ratio test p-value and likelihood confidence intervals for misspecified Cox models, as described in Shao and Guo (2025) <doi:10.48550/arXiv.2508.11851>.

Can take in images in either .jpg, .jpeg, or .png format and creates a colour palette of the most frequent colours used in the image. Also provides some custom colour palettes.

Set of functions to import COVID-19 pandemic data into R. The Brazilian COVID-19 data, obtained from the official Brazilian repository at <https://covid.saude.gov.br/>, is available at the country, region, state, and city levels. The package also downloads world-level COVID-19 data from Johns Hopkins University's repository. COVID-19 data is available from the start of follow-up until to May 5, 2023, when the World Health Organization (WHO) declared an end to the Public Health Emergency of International Concern (PHEIC) for COVID-19.

This package provides several functions to identify and analyse miRNA sponge, including popular methods for identifying miRNA sponge interactions, two types of global ceRNA regulation prediction methods and four types of context-specific prediction methods( Li Y et al.(2017) <doi:10.1093/bib/bbx137>), which are based on miRNA-messenger RNA regulation alone, or by integrating heterogeneous data, respectively. In addition, For predictive ceRNA relationship pairs, this package provides several downstream analysis algorithms, including regulatory network analysis and functional annotation analysis, as well as survival prognosis analysis based on expression of ceRNA ternary pair.

High dimensional discriminant analysis with compositional data is performed. The compositional data are first transformed using the alpha-transformation of Tsagris M., Preston S. and Wood A.T.A. (2011) <doi:10.48550/arXiv.1106.1451>, and then the High Dimensional Discriminant Analysis (HDDA) algorithm of Bouveyron C. Girard S. and Schmid C. (2007) <doi:10.1080/03610920701271095> is applied.

Visualize the connectedness of factors in two-way tables. Perform two-way filtering to improve the degree of connectedness. See Weeks & Williams (1964) <doi:10.1080/00401706.1964.10490188>.

Classification method described in Dancik et al (2011) <doi:10.1158/0008-5472.CAN-11-2427> that classifies a sample according to the class with the maximum mean (or any other function of) correlation between the test and training samples with known classes.

Collection of routines for efficient scientific computations in physics and astrophysics. These routines include utility functions, numerical computation tools, as well as visualisation tools. They can be used, for example, for generating random numbers from spherical and custom distributions, information and entropy analysis, special Fourier transforms, two-point correlation estimation (e.g. as in Landy & Szalay (1993) <doi:10.1086/172900>), binning & gridding of point sets, 2D interpolation, Monte Carlo integration, vector arithmetic and coordinate transformations. Also included is a non-exhaustive list of important constants and cosmological conversion functions. The graphics routines can be used to produce and export publication-ready scientific plots and movies, e.g. as used in Obreschkow et al. (2020, MNRAS Vol 493, Issue 3, Pages 4551â 4569). These routines include special color scales, projection functions, and bitmap handling routines.

Circular drift-diffusion model for continuous reports.

This package provides functions and a workflow to easily and powerfully calculating specificity, sensitivity and ROC curves of biomarkers combinations. Allows to rank and select multi-markers signatures as well as to find the best performing sub-signatures, now also from single-cell RNA-seq datasets. The method used was first published as a Shiny app and described in Mazzara et al. (2017) <doi:10.1038/srep45477> and further described in Bombaci & Rossi (2019) <doi:10.1007/978-1-4939-9164-8_16>, and widely expanded as a package as presented in the bioRxiv pre print Ferrari et al. <doi:10.1101/2022.01.17.476603>.

This package provides methods for interpreting CoDa (Compositional Data) regression models along the lines of "Pairwise share ratio interpretations of compositional regression models" (Dargel and Thomas-Agnan 2024) <doi:10.1016/j.csda.2024.107945>. The new methods include variation scenarios, elasticities, elasticity differences and share ratio elasticities. These tools are independent of log-ratio transformations and allow an interpretation in the original space of shares. CoDaImpact is designed to be used with the compositions package and its ecosystem.

This package provides a spatiotemperal data object in a relational data structure to separate the recording of time variant/ invariant variables. See the Journal of Statistical Software reference: <doi:10.18637/jss.v110.i07>.

This package provides function declarations and inline function definitions that facilitate communication between R and the Eigen C++ library for linear algebra and scientific computing.

This package provides a chess program which allows the user to create a game, add moves, check for legal moves and game result, plot the board, take back, read and write FEN (Forsythâ Edwards Notation). A basic chess engine based on minimax is implemented.

Partitions data points (variables) into communities/clusters, similar to clustering algorithms such as k-means and hierarchical clustering. This package implements a clustering algorithm based on a new metric CORD, defined for high-dimensional parametric or semiparametric distributions. For more details see Bunea et al. (2020), Annals of Statistics <doi:10.1214/18-AOS1794>.