Solves control systems problems relating to time/frequency response, LTI systems design and analysis, transfer function manipulations, and system conversion.

This package provides peruvian agricultural production data from the Agriculture Minestry of Peru (MINAGRI). The first version includes 6 crops: rice, quinoa, potato, sweet potato, tomato and wheat; all of them across 24 departments. Initially, in excel files which has been transformed and assembled using tidy data principles, i.e. each variable is in a column, each observation is a row and each value is in a cell. The variables variables are sowing and harvest area per crop, yield, production and price per plot, every one year, from 2004 to 2014.

There are diverse purposes such as biomarker confirmation, novel biomarker discovery, constructing predictive models, model-based prediction, and validation. It handles binary, continuous, and time-to-event outcomes at the sample or patient level. - Biomarker confirmation utilizes established functions like glm() from stats', coxph() from survival', surv_fit(), and ggsurvplot() from survminer'. - Biomarker discovery and variable selection are facilitated by three LASSO-related functions LASSO2(), LASSO_plus(), and LASSO2plus(), leveraging the glmnet R package with additional steps. - Eight versatile modeling functions are offered, each designed for predictive models across various outcomes and data types. 1) LASSO2(), LASSO_plus(), LASSO2plus(), and LASSO2_reg() perform variable selection using LASSO methods and construct predictive models based on selected variables. 2) XGBtraining() employs XGBoost for model building and is the only function not involving variable selection. 3) Functions like LASSO2_XGBtraining(), LASSOplus_XGBtraining(), and LASSO2plus_XGBtraining() combine LASSO-related variable selection with XGBoost for model construction. - All models support prediction and validation, requiring a testing dataset comparable to the training dataset. Additionally, the package introduces XGpred() for risk prediction based on survival data, with the XGpred_predict() function available for predicting risk groups in new datasets. The methodology is based on our new algorithms and various references: - Hastie et al. (1992, ISBN 0 534 16765-9), - Therneau et al. (2000, ISBN 0-387-98784-3), - Kassambara et al. (2021) <https://CRAN.R-project.org/package=survminer>, - Friedman et al. (2010) <doi:10.18637/jss.v033.i01>, - Simon et al. (2011) <doi:10.18637/jss.v039.i05>, - Harrell (2023) <https://CRAN.R-project.org/package=rms>, - Harrell (2023) <https://CRAN.R-project.org/package=Hmisc>, - Chen and Guestrin (2016) <arXiv:1603.02754>, - Aoki et al. (2023) <doi:10.1200/JCO.23.01115>.

Gives convenient access to publicly available police-recorded open crime data from large cities in the United States that are included in the Crime Open Database <https://osf.io/zyaqn/>.

Clustering, or cluster analysis, is a widely used technique in bioinformatics to identify groups of similar biological data points. Consensus clustering is an extension to clustering algorithms that aims to construct a robust result from those clustering features that are invariant under different sources of variation. For the reference, please cite the following paper: Yousefi, Melograna, et. al., (2023) <doi:10.3389/fmicb.2023.1170391>.

Perform censored quantile regression of Huang (2010) <doi:10.1214/09-AOS771>, and restore monotonicity respecting via adaptive interpolation for dynamic regression of Huang (2017) <doi:10.1080/01621459.2016.1149070>. The monotonicity-respecting restoration applies to general dynamic regression models including (uncensored or censored) quantile regression model, additive hazards model, and dynamic survival models of Peng and Huang (2007) <doi:10.1093/biomet/asm058>, among others.

Detection of change-points for variance of heteroscedastic Gaussian variables with piecewise constant variance function. Adelfio, G. (2012), Change-point detection for variance piecewise constant models, Communications in Statistics, Simulation and Computation, 41:4, 437-448, <doi:10.1080/03610918.2011.592248>.

In many studies across different disciplines, detailed measures of the variables of interest are available. If assumptions can be made regarding the direction of effects between the assessed variables, this has to be considered in the analysis. The functions in this package implement the novel approach CIEE (causal inference using estimating equations; Konigorski et al., 2018, <DOI:10.1002/gepi.22107>) for estimating and testing the direct effect of an exposure variable on a primary outcome, while adjusting for indirect effects of the exposure on the primary outcome through a secondary intermediate outcome and potential factors influencing the secondary outcome. The underlying directed acyclic graph (DAG) of this considered model is described in the vignette. CIEE can be applied to studies in many different fields, and it is implemented here for the analysis of a continuous primary outcome and a time-to-event primary outcome subject to censoring. CIEE uses estimating equations to obtain estimates of the direct effect and robust sandwich standard error estimates. Then, a large-sample Wald-type test statistic is computed for testing the absence of the direct effect. Additionally, standard multiple regression, regression of residuals, and the structural equation modeling approach are implemented for comparison.

Provide a series of functions to conduct a meta analysis of factor analysis based on co-occurrence matrices. The tool can be used to solve the factor structure (i.e. inner structure of a construct, or scale) debate in several disciplines, such as psychology, psychiatry, management, education so on. References: Shafer (2005) <doi:10.1037/1040-3590.17.3.324>; Shafer (2006) <doi:10.1002/jclp.20213>; Loeber and Schmaling (1985) <doi:10.1007/BF00910652>.

This package provides comprehensive tools for extracting and analyzing scientific content from PDF documents, including citation extraction, reference matching, text analysis, and bibliometric indicators. Supports multi-column PDF layouts, CrossRef API <https://www.crossref.org/documentation/retrieve-metadata/rest-api/> integration, and advanced citation parsing.

Execute Nonlinear Mixed Effects (NLME) models for pharmacometrics using a shiny interface. Specify engine parameters and select from different run options, including simple estimation, stepwise covariate search, bootstrapping, simulation, visual predictive check, and more. Models are executed using the Certara.RsNLME package.

Package to assess the calibration of probabilistic classifiers using confidence bands for monotonic functions. Besides testing the classical goodness-of-fit null hypothesis of perfect calibration, the confidence bands calculated within that package facilitate inverted goodness-of-fit tests whose rejection allows for a sought-after conclusion of a sufficiently well-calibrated model. The package creates flexible graphical tools to perform these tests. For construction details see also Dimitriadis, Dümbgen, Henzi, Puke, Ziegel (2022) <arXiv:2203.04065>.

This package provides a comprehensive framework for time series omics analysis, integrating changepoint detection, smooth and shape-constrained trends, and uncertainty quantification. It supports gene- and transcript-level inferences, p-value aggregation for improved power, and both case-only and case-control designs. It includes an interactive shiny interface. The methods are described in Yates et al. (2024) <doi:10.1101/2024.12.22.630003>.

Several nonparametric estimators of autocovariance functions. Procedures for constructing their confidence regions by using bootstrap techniques. Methods to correct autocovariance estimators and several tools for analysing and comparing them. Supplementary functions, including kernel computations and discrete cosine Fourier transforms. For more details see Bilchouris and Olenko (2025) <doi:10.17713/ajs.v54i1.1975>.

Computation of Multiscale Codependence Analysis and spatial eigenvector maps.

Git hook scripts are useful for identifying simple issues before submission to code review. captain (hook) is an R package to manage and run git pre-commit hooks.

Calculate date of birth, age, and gender, and generate anonymous sequence numbers from CPR numbers. <https://en.wikipedia.org/wiki/Personal_identification_number_(Denmark)>.

Decorate functions to make them return enhanced output. The enhanced output consists in an object of type chronicle containing the result of the function applied to its arguments, as well as a log detailing when the function was run, what were its inputs, what were the errors (if the function failed to run) and other useful information. Tools to handle decorated functions are included, such as a forward pipe operator that makes chaining decorated functions possible.

An interactive platform for clustering analysis and teaching based on the shiny web application framework. Supports multiple popular clustering algorithms including k-means, hierarchical clustering, DBSCAN (Density-Based Spatial Clustering of Applications with Noise), PAM (Partitioning Around Medoids), GMM (Gaussian Mixture Model), and spectral clustering. Users can upload datasets or use built-in ones, visualize clustering results using dimensionality reduction methods such as Principal Component Analysis (PCA) and t-distributed Stochastic Neighbor Embedding (t-SNE), evaluate clustering quality via silhouette plots, and explore method-specific visualizations and guides. For details on implemented methods, see: Reynolds (2009, ISBN:9781598296975) for GMM; Luxburg (2007) <doi:10.1007/s11222-007-9033-z> for spectral clustering.

This comprehensive framework for periodic time series modeling is designated as "CLIC" (The LIC for Distributed Cosine Regression Analysis) analysis. It is predicated on the assumption that the underlying data exhibits complex periodic structures beyond simple harmonic components. The philosophy of the method is articulated in Guo G. (2020) <doi:10.1080/02664763.2022.2053949>.

This software tool is designed to generate new cohorts utilizing data from previously instantiated cohorts. It employs interval algebra operators such as UNION, INTERSECT, and MINUS to manipulate the data within the instantiated cohorts and create new cohorts.

This package provides methods for the import/export and automated analysis of concept maps and concept landscapes (sets of concept maps).

Cluster analysis of a set of variables. Variables can be quantitative, qualitative or a mixture of both.

Filtering, also known as gating, of flow cytometry samples using the curvHDR method, which is described in Naumann, U., Luta, G. and Wand, M.P. (2010) <DOI:10.1186/1471-2105-11-44>.