Run simple direct gravitational N-body simulations. The package can access different external N-body simulators (e.g. GADGET-4 by Springel et al. (2021) <doi:10.48550/arXiv.2010.03567>), but also has a simple built-in simulator. This default simulator uses a variable block time step and lets the user choose between a range of integrators, including 4th and 6th order integrators for high-accuracy simulations. Basic top-hat smoothing is available as an option. The code also allows the definition of background particles that are fixed or in uniform motion, not subject to acceleration by other particles.

Statistical inference with non-probability samples when auxiliary information from external sources such as probability samples or population totals or means is available. The package implements various methods such as inverse probability (propensity score) weighting, mass imputation and doubly robust approach. Details can be found in: Chen et al. (2020) <doi:10.1080/01621459.2019.1677241>, Yang et al. (2020) <doi:10.1111/rssb.12354>, Kim et al. (2021) <doi:10.1111/rssa.12696>, Yang et al. (2021) <https://www150.statcan.gc.ca/n1/pub/12-001-x/2021001/article/00004-eng.htm> and Wu (2022) <https://www150.statcan.gc.ca/n1/pub/12-001-x/2022002/article/00002-eng.htm>. For details on the package and its functionalities see <doi:10.48550/arXiv.2504.04255>.

Features tools for the network data analysis and community detection. Provides multiple methods for fitting, model selection and goodness-of-fit testing in degree-corrected stochastic blocks models. Most of the computations are fast and scalable for sparse networks, esp. for Poisson versions of the models. Implements the following: Amini, Chen, Bickel and Levina (2013) <doi:10.1214/13-AOS1138> Bickel and Sarkar (2015) <doi:10.1111/rssb.12117> Lei (2016) <doi:10.1214/15-AOS1370> Wang and Bickel (2017) <doi:10.1214/16-AOS1457> Zhang and Amini (2020) <arXiv:2012.15047> Le and Levina (2022) <doi:10.1214/21-EJS1971>.

This package contains methods described by Dennis Helsel in his book "Statistics for Censored Environmental Data using Minitab and R" (2011) and courses and videos at <https://practicalstats.com>. This package incorporates functions of NADA and adds new functionality.

This package provides a function designed to estimate the minimal sample size required to attain a specific statistical power in the context of linear regression and logistic regression models through simulations.

In semi-structured interviews that use the framework method, it is not always clear how refinements to interview questions affect the decision of when to stop interviews. The trend of novel and duplicate interview codes (novel codes are information that other interviewees have not previously mentioned) provides insight into the richness of qualitative information. This package provides tools to visualise when refinements occur and how that affects the trends of novel and duplicate codes. These visualisations, when used progressively as new interviews are finished, can help the researcher to decide on a stopping point for their interviews. For context, see Wong et al., (2023) <doi:10.1177/16094069231220773>.

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the rxode2 package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>). This package is for ggplot2 plotting methods for nlmixr2 objects.

Simplify the exploratory data analysis process for multiple network data sets with the help of hierarchical clustering, consensus clustering and heatmaps. Multiple network data consists of multiple disjoint networks that have common variables (e.g. ego networks). This package contains the necessary tools for exploring such data, from the data pre-processing stage to the creation of dynamic visualizations.

Piecewise constant hazard functions are used to flexibly model survival distributions with non-proportional hazards and to simulate data from the specified distributions. A function to calculate weighted log-rank tests for the comparison of two hazard functions is included. Also, a function to calculate a test using the maximum of a set of test statistics from weighted log-rank tests (MaxCombo test) is provided. This test utilizes the asymptotic multivariate normal joint distribution of the separate test statistics. The correlation is estimated from the data. These methods are described in Ristl et al. (2021) <doi:10.1002/pst.2062>. Finally, a function is provided for the estimation and inferential statistics of various parameters that quantify the difference between two survival curves. Eligible parameters are differences in survival probabilities, log survival probabilities, complementary log log (cloglog) transformed survival probabilities, quantiles of the survival functions, log transformed quantiles, restricted mean survival times, as well as an average hazard ratio, the Cox model score statistic (logrank statistic), and the Cox-model hazard ratio. Adjustments for multiple testing and simultaneous confidence intervals are calculated using a multivariate normal approximation to the set of selected parameters.

This package provides streamlined installation for packages from the natverse', a suite of R packages for computational neuroanatomy built on top of the nat NeuroAnatomy Toolbox package. Installation of the complete natverse suite requires a GitHub user account and personal access token GITHUB_PAT'. natmanager will help the end user set this up if necessary.

We developed an inference tool based on approximate Bayesian computation to decipher network data and assess the strength of the inferred links between network's actors. It is a new multi-level approximate Bayesian computation (ABC) approach. At the first level, the method captures the global properties of the network, such as a scale-free structure and clustering coefficients, whereas the second level is targeted to capture local properties, including the probability of each couple of genes being linked. Up to now, Approximate Bayesian Computation (ABC) algorithms have been scarcely used in that setting and, due to the computational overhead, their application was limited to a small number of genes. On the contrary, our algorithm was made to cope with that issue and has low computational cost. It can be used, for instance, for elucidating gene regulatory network, which is an important step towards understanding the normal cell physiology and complex pathological phenotype. Reverse-engineering consists in using gene expressions over time or over different experimental conditions to discover the structure of the gene network in a targeted cellular process. The fact that gene expression data are usually noisy, highly correlated, and have high dimensionality explains the need for specific statistical methods to reverse engineer the underlying network.

This package provides tools for detecting numeric persistence ("spells") and rigidity patterns in time-ordered numeric data. The package identifies periods of stability, computes spell-based rigidity metrics, and provides plain-language interpretations suitable for policy and applied analysis.

This package contains functions useful for debugging, set operations on vectors, and UTC date and time functionality. It adds a few vector manipulation verbs to purrr and dplyr packages. It can also generate an R file to install and update packages to simplify deployment into production. The functions were developed at the data science firm Numeract LLC and are used in several packages and projects.

This package provides functions to calculate the normalised Lineage-Through- Time (nLTT) statistic, given two phylogenetic trees. The nLTT statistic measures the difference between two Lineage-Through-Time curves, where each curve is normalised both in time and in number of lineages.

This package implements the nonparametric trend test for one or several samples as proposed by Bathke (2009) <doi:10.1007/s00184-008-0171-x>. The method provides a unified framework for analyzing trends in both independent and dependent data samples, making it a versatile tool for various study designs. The package allows for the evaluation of different trend alternatives, including two-sided (general trend), monotonic increasing, and monotonic decreasing trends. As a nonparametric procedure, it does not require the assumption of data normality, offering a robust alternative to parametric tests.

Macros to generate nimble code from a concise syntax. Included are macros for generating linear modeling code using a formula-based syntax and for building for() loops. For more details review the nimble manual: <https://r-nimble.org/html_manual/cha-writing-models.html#subsec:macros>.

This package implements the nonparametric causality-in-quantiles test (in mean or variance), returning a test object with an S3 plot() method. The current implementation uses one lag of each series (first-order Granger causality setup). Methodology is based on Balcilar, Gupta, and Pierdzioch (2016a) <doi:10.1016/j.resourpol.2016.04.004> and Balcilar et al. (2016) <doi:10.1007/s11079-016-9388-x>.

This package provides functions to produce advanced ascii graphics, directly to the terminal window. This package utilizes the txtplot() function from the txtplot package, to produce text-based histograms, empirical cumulative distribution function plots, scatterplots with fitted and regression lines, quantile plots, density plots, image plots, and contour plots.

Enables correction for technical variance in raw quantitative reverse transcription polymerase chain reaction (qRT-PCR) data using the least squares-based NORMAgene data-driven normalization algorithm originally described by Heckmann et al. (2011) <doi:10.1186/1471-2105-12-250>. Performs normalization of raw crossing threshold values (CT) and also calculates relative variability metrics that can be used to assess the impact of normalization on variance.

It provides ensemble capabilities to supervised and unsupervised learning models predictions without using training labels. It decides the relative weights of the different models predictions by using best models predictions as response variable and rest of the mo. User can decide the best model, therefore, It provides freedom to user to ensemble models based on their design solutions.

Accompanies the book "Nonparametric Statistical Methods Using R, 2nd Edition" by Kloke and McKean (2024, ISBN:9780367651350). Includes methods, datasets, and random number generation useful for the study of robust and/or nonparametric statistics. Emphasizes classical nonparametric methods for a variety of designs --- especially one-sample and two-sample problems. Includes methods for general scores, including estimation and testing for the two-sample location problem as well as Hogg's adaptive method.

Generates functional Magnetic Resonance Imaging (fMRI) time series or 4D data. Some high-level functions are created for fast data generation with only a few arguments and a diversity of functions to define activation and noise. For more advanced users it is possible to use the low-level functions and manipulate the arguments. See Welvaert et al. (2011) <doi:10.18637/jss.v044.i10>.

This package contains the following 5 nonparametric hypothesis tests: The Sign Test, The 2 Sample Median Test, Miller's Jackknife Procedure, Cochran's Q Test, & The Stuart-Maxwell Test.

The Bayesian hierarchical model named antigen-T cell interaction estimation is to estimate the history of the immune pressure on the evolution of the tumor clones.The model is based on the estimation result from Andrew Roth (2014) <doi:10.1038/nmeth.2883>.