This package performs the multiple testing procedures of Cox (2011) <doi:10.5170/CERN-2011-006> and Wong and Cox (2007) <doi:10.1080/02664760701240014>.

Fits and tests meta regression models and generates a number of useful test statistics: next to t- and z-tests, the likelihood ratio, bartlett corrected likelihood ratio and permutation tests are performed on the model coefficients.

Analyzes subject-level data in clinical trials using the metalite data structure. The package simplifies the workflow to create production-ready tables, listings, and figures discussed in the subject-level analysis chapters of "R for Clinical Study Reports and Submission" by Zhang et al. (2022) <https://r4csr.org/>.

This package provides functions similar to the SAS macros previously provided to accompany Collins, Dziak, and Li (2009) <DOI:10.1037/a0015826> and Dziak, Nahum-Shani, and Collins (2012) <DOI:10.1037/a0026972>, papers which outline practical benefits and challenges of factorial and fractional factorial experiments for scientists interested in developing biological and/or behavioral interventions, especially in the context of the multiphase optimization strategy (see Collins, Kugler & Gwadz 2016) <DOI:10.1007/s10461-015-1145-4>. The package currently contains three functions. First, RelativeCosts1() draws a graph of the relative cost of complete and reduced factorial designs versus other alternatives. Second, RandomAssignmentGenerator() returns a dataframe which contains a list of random numbers that can be used to conveniently assign participants to conditions in an experiment with many conditions. Third, FactorialPowerPlan() estimates the power, detectable effect size, or required sample size of a factorial or fractional factorial experiment, for main effects or interactions, given several possible choices of effect size metric, and allowing pretests and clustering.

Determines single or multiple modes (most frequent values). Checks if missing values make this impossible, and returns NA in this case. Dependency-free source code. See Franzese and Iuliano (2019) <doi:10.1016/B978-0-12-809633-8.20354-3>.

This package provides a set of functions which use the Expectation Maximisation (EM) algorithm (Dempster, A. P., Laird, N. M., and Rubin, D. B. (1977) <doi:10.1111/j.2517-6161.1977.tb01600.x> Maximum likelihood from incomplete data via the EM algorithm, Journal of the Royal Statistical Society, 39(1), 1--22) to take a finite mixture model approach to clustering. The package is designed to cluster multivariate data that have categorical and continuous variables and that possibly contain missing values. The method is described in Hunt, L. and Jorgensen, M. (1999) <doi:10.1111/1467-842X.00071> Australian & New Zealand Journal of Statistics 41(2), 153--171 and Hunt, L. and Jorgensen, M. (2003) <doi:10.1016/S0167-9473(02)00190-1> Mixture model clustering for mixed data with missing information, Computational Statistics & Data Analysis, 41(3-4), 429--440.

This package provides functions for multivariate and propensity score matching and for finding optimal balance based on a genetic search algorithm. A variety of univariate and multivariate metrics to determine if balance has been obtained are also provided. For details, see the paper by Jasjeet Sekhon (2007, <doi:10.18637/jss.v042.i07>).

This package provides functions for calculating the point and interval estimates of the natural indirect effect (NIE), total effect (TE), and mediation proportion (MP), based on the product approach. We perform the methods considered in Cheng, Spiegelman, and Li (2021) Estimating the natural indirect effect and the mediation proportion via the product method.

Regularly spaced grids containing continuous data are transformed to contour polygons. A grid can be defined by a data.frame (x, y, value), an sf object or a raster from terra'.

Animal abundance estimation via conventional, multiple covariate and mark-recapture distance sampling (CDS/MCDS/MRDS). Detection function fitting is performed via maximum likelihood. Also included are diagnostics and plotting for fitted detection functions. Abundance estimation is via a Horvitz-Thompson-like estimator.

This package provides a container for data used by the mapindia package. The data used by mapindia has been extracted into this package so that the file size of the mapindia package can be reduced considerably. The data in this package will be updated when latest data is available.

This package provides a single unified interface for computing a wide variety of classical and modern correlation and association measures. Continuous methods include classical correlations (Pearson, Spearman, Kendall), modern dependence measures (distance correlation, maximal information coefficient, Hilbert-Schmidt independence criterion, Chatterjee's xi, Hoeffding's D, mutual information), robust correlations (biweight midcorrelation, percentage bend, Winsorized), ordinal correlations (polychoric, tetrachoric), partial and semi-partial correlations, and nonparametric measures (ball correlation, Bergsma-Dassios tau*). Categorical association measures (Cramer's V, phi coefficient, Goodman-Kruskal gamma, Somers D, contingency coefficient, Tschuprow's T) are available via moderncor_cat().

This package performs multivariate meta-analysis for high-dimensional data to integrate and collectively analyse individual-level data from multiple studies, as well as to combine summary estimates. This approach accounts for correlation between outcomes, incorporates withinâ and betweenâ study variability, handles missing values, and uses shrinkage estimation to accommodate high dimensionality. The MetaHD R package provides access to our multivariate meta-analysis approach, along with a comprehensive suite of existing meta-analysis methods, including fixed-effects and random-effects models, Fisherâ s method, Stoufferâ s method, the weighted Z method, Lancasterâ s method, the weighted Fisherâ s method, and vote-counting approach. A detailed vignette with example datasets and code for data preparation and analysis is available at <https://alyshadelivera.github.io/MetaHD_vignette/>.

This package implements FUSE (Functional Segmentation of DNA methylation data), a data-driven method for identifying spatially coherent DNA methylation segments from whole-genome bisulfite sequencing (WGBS) count data. The method performs hierarchical clustering of CpG sites based on methylated and unmethylated read counts across multiple samples and determines the optimal number of segments using an information criterion (AIC or BIC). Resulting segments represent regions with homogeneous methylation profiles across the input cohort while allowing sample-specific methylation levels. The package provides functions for clustering, model selection, tree cutting, segment-level summarization, and visualization. Input can be supplied as count matrices or extracted directly from BSseq and methrix objects.

This package provides essential tools for the pre-processing techniques of matching and weighting multiply imputed datasets. The package includes functions for matching within and across multiply imputed datasets using various methods, estimating weights for units in the imputed datasets using multiple weighting methods, calculating causal effect estimates in each matched or weighted dataset using parametric or non-parametric statistical models, and pooling the resulting estimates according to Rubin's rules (please see <https://journal.r-project.org/archive/2021/RJ-2021-073/> for more details).

This package provides a fast and general method for restructuring classical longitudinal observational data into augmented transition data suitable for multi-state modeling with the msm package. Works with any longitudinal data where subjects accumulate repeated observations with start and end times and an optional terminal outcome. Methods are described in Grossetti, Ieva and Paganoni (2018) <doi:10.1007/s10729-017-9400-z>.

Functions, data sets, analyses and examples from the book `An Introduction to Applied Multivariate Analysis with R (Brian S. Everitt and Torsten Hothorn, Springer, 2011).

Helps calculate statistical values commonly used in meta-analysis. It provides several methods to compute different forms of standardized mean differences, as well as other values such as standard errors and standard deviations. The methods used in this package are described in the following references: Altman D G, Bland J M. (2011) <doi:10.1136/bmj.d2090> Borenstein, M., Hedges, L.V., Higgins, J.P.T. and Rothstein, H.R. (2009) <doi:10.1002/9780470743386.ch4> Chinn S. (2000) <doi:10.1002/1097-0258(20001130)19:22%3C3127::aid-sim784%3E3.0.co;2-m> Cochrane Handbook (2011) <https://www.cochrane.org/authors/handbooks-and-manuals/handbook/archive/v5.1.0> Cooper, H., Hedges, L. V., & Valentine, J. C. (2009) <https://psycnet.apa.org/record/2009-05060-000> Cohen, J. (1977) <https://psycnet.apa.org/record/1987-98267-000> Ellis, P.D. (2009) <https://www.psychometrica.de/effect_size.html> Goulet-Pelletier, J.-C., & Cousineau, D. (2018) <doi:10.20982/tqmp.14.4.p242> Hedges, L. V. (1981) <doi:10.2307/1164588> Hedges L. V., Olkin I. (1985) <doi:10.1016/C2009-0-03396-0> Murad M H, Wang Z, Zhu Y, Saadi S, Chu H, Lin L et al. (2023) <doi:10.1136/bmj-2022-073141> Mayer M (2023) <https://search.r-project.org/CRAN/refmans/confintr/html/ci_proportion.html> Stackoverflow (2014) <https://stats.stackexchange.com/questions/82720/confidence-interval-around-binomial-estimate-of-0-or-1> Stackoverflow (2018) <https://stats.stackexchange.com/q/338043>.

Imputes missing values of an incomplete data matrix by minimizing the Mahalanobis distance of each sample from the overall mean [Labita, GJ.D. and Tubo, B.F. (2024) <doi:10.24412/1932-2321-2024-278-115-123>].

Estimate diagnostic classification models (also called cognitive diagnostic models) with Stan'. Diagnostic classification models are confirmatory latent class models, as described by Rupp et al. (2010, ISBN: 978-1-60623-527-0). Automatically generate Stan code for the general loglinear cognitive diagnostic diagnostic model proposed by Henson et al. (2009) <doi:10.1007/s11336-008-9089-5> and other subtypes that introduce additional model constraints. Using the generated Stan code, estimate the model evaluate the model's performance using model fit indices, information criteria, and reliability metrics.

This package provides a compilation of more than 80 functions designed to quantitatively and visually evaluate prediction performance of regression (continuous variables) and classification (categorical variables) of point-forecast models (e.g. APSIM, DSSAT, DNDC, supervised Machine Learning). For regression, it includes functions to generate plots (scatter, tiles, density, & Bland-Altman plot), and to estimate error metrics (e.g. MBE, MAE, RMSE), error decomposition (e.g. lack of accuracy-precision), model efficiency (e.g. NSE, E1, KGE), indices of agreement (e.g. d, RAC), goodness of fit (e.g. r, R2), adjusted correlation coefficients (e.g. CCC, dcorr), symmetric regression coefficients (intercept, slope), and mean absolute scaled error (MASE) for time series predictions. For classification (binomial and multinomial), it offers functions to generate and plot confusion matrices, and to estimate performance metrics such as accuracy, precision, recall, specificity, F-score, Cohen's Kappa, G-mean, and many more. For more details visit the vignettes <https://adriancorrendo.github.io/metrica/>.

An API wrapper for the Monash University Probabilistic Footy Tipping Competition <https://probabilistic-footy.monash.edu/~footy/index.shtml>. Allows users to submit tips directly to the competition from R.

In breeding experiments, mating environmental (ME) designs are very popular as mating designs are directly implemented in the field environment using block or row-column designs. Here, three functions are given related to three new methods which will generate mating diallel cross designs (Hinkelmann and Kempthorne, 1963<doi:10.2307/2333899>) or mating environmental (ME) designs along with design parameters, C matrix, eigenvalues (EVs), degree of fractionations (DF) and canonical efficiency factor (CEF). Another one function is added to check the properties of a given ME diallel cross design.

The multiple instance data set consists of many independent subjects (called bags) and each subject is composed of several components (called instances). The outcomes of such data set are binary or categorical responses, and, we can only observe the subject-level outcomes. For example, in manufacturing processes, a subject is labeled as "defective" if at least one of its own components is defective, and otherwise, is labeled as "non-defective". The milr package focuses on the predictive model for the multiple instance data set with binary outcomes and performs the maximum likelihood estimation with the Expectation-Maximization algorithm under the framework of logistic regression. Moreover, the LASSO penalty is attached to the likelihood function for simultaneous parameter estimation and variable selection.