This package provides functions and Examples in Sample Size Calculation in Clinical Research.

Manager of tick-by-tick transaction data that performs cleaning', aggregation and import in an efficient and fast way. The package engine, written in C++, exploits the zlib and gzstream libraries to handle gzipped data without need to uncompress them. Cleaning and aggregation are performed according to Brownlees and Gallo (2006) <DOI:10.1016/j.csda.2006.09.030>. Currently, TAQMNGR processes raw data from WRDS (Wharton Research Data Service, <https://wrds-web.wharton.upenn.edu/wrds/>).

This package provides methods for low-rank tensor regression with tensor-valued predictors and scalar covariates. Model estimation is performed using stochastic optimization with random-walk updates for low-rank factor matrices. Computationally intensive components for coefficient estimation and prediction are implemented in C++ via Rcpp'. The package also includes tools for cross-validation and prediction error assessment.

This package provides tools to calculate trait probability density functions (TPD) at any scale (e.g. populations, species, communities). TPD functions are used to compute several indices of functional diversity, as well as its partition across scales. These indices constitute a unified framework that incorporates the underlying probabilistic nature of trait distributions into uni- or multidimensional functional trait-based studies. See Carmona et al. (2016) <doi:10.1016/j.tree.2016.02.003> for further information.

This package provides several confidence interval and testing procedures, based on either semiparametric (using event-specific win ratios) or nonparametric measures, including the ratio of integrated cumulative hazard (RICH) and the ratio of integrated transformed cumulative hazard (RITCH), for treatment effect inference with terminal and non-terminal events under competing risks. The semiparametric results were developed in Yang et al. (2022 <doi:10.1002/sim.9266>), and the nonparametric results were developed in Yang (2025 <doi:10.1002/sim.70205>). For comparison, results for the win ratio (Finkelstein and Schoenfeld 1999 <doi:10.1002/(SICI)1097-0258(19990615)18:11%3C1341::AID-SIM129%3E3.0.CO;2-7>), Pocock et al. 2012 <doi:10.1093/eurheartj/ehr352>, and Bebu and Lachin 2016 <doi:10.1093/biostatistics/kxv032>) are included. The package also supports univariate survival analysis with a single event. In this package, effect size estimates and confidence intervals are obtained for each event type, and several testing procedures are implemented for the global null hypothesis of no treatment effect on either terminal or non-terminal events. Furthermore, a test of proportional hazards assumptions, under which the event-specific win ratios converge to hazard ratios, and a test of equal hazard ratios, are provided. For summarizing the treatment effect across all events, confidence intervals for linear combinations of the event-specific win ratios, RICH, or RITCH are available using pre-determined or data-driven weights. Asymptotic properties of these inference procedures are discussed in Yang et al. (2022 <doi:10.1002/sim.9266>) and Yang (2025 <doi:10.1002/sim.70205>).

This package implements nonlinear autoregressive (AR) time series models. For univariate series, a non-parametric approach is available through additive nonlinear AR. Parametric modeling and testing for regime switching dynamics is available when the transition is either direct (TAR: threshold AR) or smooth (STAR: smooth transition AR, LSTAR). For multivariate series, one can estimate a range of TVAR or threshold cointegration TVECM models with two or three regimes. Tests can be conducted for TVAR as well as for TVECM (Hansen and Seo 2002 and Seo 2006).

This package provides functions for compounding and discounting calculations included here serve as a complete reference for various scenarios of time value of money. Raymond M. Brooks (â Financial Management,â 2018, ISBN: 9780134730417). Sheridan Titman, Arthur J. Keown, John D. Martin (â Financial Management: Principles and Applications,â 2017, ISBN: 9780134417219). Jonathan Berk, Peter DeMarzo, David Stangeland, Andras Marosi (â Fundamentals of Corporate Finance,â 2019, ISBN: 9780134735313). S. A. Hummelbrunner, Kelly Halliday, Ali R. Hassanlou (â Contemporary Business Mathematics with Canadian Applications,â 2020, ISBN: 9780135285015).

Efficient implementations of functions for the creation, modification and analysis of phylogenetic trees. Applications include: generation of trees with specified shapes; tree rearrangement; analysis of tree shape; rooting of trees and extraction of subtrees; calculation and depiction of split support; plotting the position of rogue taxa (Klopfstein & Spasojevic 2019) <doi:10.1371/journal.pone.0212942>; calculation of ancestor-descendant relationships, of stemwardness (Asher & Smith, 2022) <doi:10.1093/sysbio/syab072>, and of tree balance (Mir et al. 2013, Lemant et al. 2022) <doi:10.1016/j.mbs.2012.10.005>, <doi:10.1093/sysbio/syac027>; artificial extinction (Asher & Smith, 2022) <doi:10.1093/sysbio/syab072>; import and export of trees from Newick, Nexus (Maddison et al. 1997) <doi:10.1093/sysbio/46.4.590>, and TNT <https://www.lillo.org.ar/phylogeny/tnt/> formats; and analysis of splits and cladistic information.

This package provides functions for the analysis of time series using copula models. The package is based on methodology described in the following references. McNeil, A.J. (2021) <doi:10.3390/risks9010014>, Bladt, M., & McNeil, A.J. (2021) <doi:10.1016/j.ecosta.2021.07.004>, Bladt, M., & McNeil, A.J. (2022) <doi:10.1515/demo-2022-0105>.

Makes data wrangling with ID-related aspects more comfortable. Provides functions that make it easy to inspect various subject-generated ID codes (SGIC) for plausibility. Also helps with inspecting other common identifiers, ensuring that your data stays clean and reliable.

Objects to manipulate sequential and seasonal time series. Sequential time series based on time instants and time duration are handled. Both can be regularly or unevenly spaced (overlapping duration are allowed). Only POSIX* format are used for dates and times. The following classes are provided : POSIXcti', POSIXctp', TimeIntervalDataFrame', TimeInstantDataFrame', SubtimeDataFrame ; methods to switch from a class to another and to modify the time support of series (hourly time series to daily time series for instance) are also defined. Tools provided can be used for instance to handle environmental monitoring data (not always produced on a regular time base).

Method to estimate the effect of the trend in predictor variables on the observed trend of the response variable using mixed models with temporal autocorrelation. See Fernández-Martà nez et al. (2017 and 2019) <doi:10.1038/s41598-017-08755-8> <doi:10.1038/s41558-018-0367-7>.

Node centrality measures for temporal networks. Available measures are temporal degree centrality, temporal closeness centrality and temporal betweenness centrality defined by Kim and Anderson (2012) <doi:10.1103/PhysRevE.85.026107>. Applying the REN algorithm by Hanke and Foraita (2017) <doi:10.1186/s12859-017-1677-x> when calculating the centrality measures keeps the computational running time linear in the number of graph snapshots. Further, all methods can run in parallel up to the number of nodes in the network.

The ESTIMATE package infers tumor purity from expression data as a function of immune and stromal infiltrate, but requires writing of intermediate files, is un-pipeable, and performs poorly when presented with modern datasets with current gene symbols. tidyestimate a fast, tidy, modern reimagination of ESTIMATE (2013) <doi:10.1038/ncomms3612>.

For when your colors absolutely should not be excluded from the narrative.

Tidal analysis of evenly spaced observed time series (time step 1 to 60 min) with or without shorter gaps using the harmonic representation of inequalities. The analysis should preferably cover an observation period of at least 19 years. For shorter periods low frequency constituents are not taken into account, in accordance with the Rayleigh-Criterion. The main objective of this package is to synthesize or predict a tidal time series.

The tinytest package offers a light-weight zero-dependency unit-testing framework to which this package adds support via the diffobj package for diff'-style textual comparison of R objects, as well as via tinysnapshot package for visual differences in plots.

This package provides the estimation of a time-dependent covariance matrix of returns with the intended use for portfolio optimization. The package offers methods for determining the optimal number of factors to be used in the covariance estimation, a hypothesis test of time-varying covariance, and user-friendly functions for portfolio optimization and rolling window evaluation. The local PCA method, method for determining the number of factors, and associated hypothesis test are based on Su and Wang (2017) <doi:10.1016/j.jeconom.2016.12.004>. The approach to time-varying portfolio optimization follows Fan et al. (2024) <doi:10.1016/j.jeconom.2022.08.007>. The regularisation applied to the residual covariance matrix adopts the technique introduced by Chen et al. (2019) <doi:10.1016/j.jeconom.2019.04.025>.

Location-Scale based distributions parameterized in terms of mean, standard deviation, skew and shape parameters and estimation using automatic differentiation. Distributions include the Normal, Student and GED as well as their skewed variants ('Fernandez and Steel'), the Johnson SU', and the Generalized Hyperbolic. Also included is the semi-parametric piece wise distribution ('spd') with Pareto tails and kernel interior.

Data handling and estimation functions for animal movement estimation from archival or satellite tags. Helper functions are included for making image summaries binned by time interval from Markov Chain Monte Carlo simulations.

This data set provides information on the fate of passengers on the fatal maiden voyage of the ocean liner "Titanic", summarized according to economic status (class), sex, age and survival. Whereas the base R Titanic data found by calling data("Titanic") is an array resulting from cross-tabulating 2201 observations, these data sets are the individual non-aggregated observations and formatted in a machine learning context with a training sample, a testing sample, and two additional data sets that can be used for deeper machine learning analysis. These data sets are also the data sets downloaded from the Kaggle competition and thus lowers the barrier to entry for users new to R or machine learing.

Type hints are special comments within a function body indicating the intended nature of the function's arguments in terms of data types, dimensions and permitted values. The actual parameters with which the function is called are evaluated against these type hint comments at run-time.

Download daily interest rates from the US Treasury XML feed. Leveraging <https://home.treasury.gov/treasury-daily-interest-rate-xml-feed>, this package serves as a wrapper, facilitating the retrieval of daily treasury rates across various categories, including par yield curves, treasury bills, long-term rates, and real yield curves.

Overall predictive performance is measured by a mean score (or loss), which decomposes into miscalibration, discrimination, and uncertainty components. The main focus is visualization of these distinct and complementary aspects in joint displays. See Dimitriadis, Gneiting, Jordan, Vogel (2024) <doi:10.1016/j.ijforecast.2023.09.007>.