Identifies clinically relevant concepts in Observational Medical Outcomes Partnership Common Data Model cohorts using an enrichment-based workflow. Defines target and control cohorts and extracts medical interventions that are over-represented in the target cohort during the observation period. Users can tune filtering and selection thresholds. The workflow includes chi-squared tests for two proportions with Yates continuity correction, logistic tests, and hierarchy and correlation mappings for relevant concepts. The results can be optionally explored using the bundled graphical user interface. For workflow details and examples, see <https://healthinformaticsut.github.io/CohortContrast/>.

An interactive document on the topic of cluster analysis using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://analyticmodels.shinyapps.io/ClusterAnalysis/>.

Utility functions to facilitate the import, the reporting and analysis of clinical data. Example datasets in SDTM and ADaM format, containing a subset of patients/domains from the CDISC Pilot 01 study are also available as R datasets to demonstrate the package functionalities.

Calculates correlation of variables and displays the results graphically. Included panel functions can display points, shading, ellipses, and correlation values with confidence intervals. See Friendly (2002) <doi:10.1198/000313002533>.

This package implements cointegration/co-trending rank selection algorithm in Guo and Shintani (2013) "Consistent co-trending rank selection when both stochastic and nonlinear deterministic trends are present". The Econometrics Journal 16: 473-483 <doi:10.1111/j.1368-423X.2012.00392.x>. Numbered examples correspond to Feb 2011 preprint <http://www.fas.nus.edu.sg/ecs/events/seminar/seminar-papers/05Apr11.pdf>.

Estimation, prediction, and simulation of nonstationary Gaussian process with modular covariate-based covariance functions. Sources of nonstationarity, such as spatial mean, variance, geometric anisotropy, smoothness, and nugget, can be considered based on spatial characteristics. An induced compact-supported nonstationary covariance function is provided, enabling fast and memory-efficient computations when handling densely sampled domains.

Computes effect sizes, standard errors, and confidence intervals for total, direct, and indirect effects in continuous-time mediation models as described in Pesigan, Russell, and Chow (2025) <doi:10.1037/met0000779>.

Convert text into synthesized speech and get a list of supported voices for a region. Microsoft's Cognitive Services Text to Speech REST API <https://learn.microsoft.com/en-us/azure/cognitive-services/speech-service/rest-text-to-speech?tabs=streaming> supports neural text to speech voices, which support specific languages and dialects that are identified by locale.

This package performs Bayesian nonparametric density estimation using Martingale posterior distributions including the Copula Resampling (CopRe) algorithm. Also included are a Gibbs sampler for the marginal Gibbs-type mixture model and an extension to include full uncertainty quantification via a predictive sequence resampling (SeqRe) algorithm. The CopRe and SeqRe samplers generate random nonparametric distributions as output, leading to complete nonparametric inference on posterior summaries. Routines for calculating arbitrary functionals from the sampled distributions are included as well as an important algorithm for finding the number and location of modes, which can then be used to estimate the clusters in the data using, for example, k-means. Implements work developed in Moya B., Walker S. G. (2022). <doi:10.48550/arxiv.2206.08418>, Fong, E., Holmes, C., Walker, S. G. (2021) <doi:10.48550/arxiv.2103.15671>, and Escobar M. D., West, M. (1995) <doi:10.1080/01621459.1995.10476550>.

Supports quantitative research in scientometrics and bibliometrics. Provides various tools for preprocessing bibliographic data retrieved, e.g., from Elsevier's Scopus, computing bibliometric impact of individuals, or modelling phenomena encountered in the social sciences. This package is deprecated; see agop instead.

Implementation of Clarke's distribution-free test of non-nested models. Currently supported model functions are: lm(), glm() ('binomial', poisson', negative binomial links), polr() ('MASS'), clm() ('ordinal'), and multinom() ('nnet'). For more information on the test, see Clarke (2007) <doi:10.1093/pan/mpm004>.

Statistical tests for the comparison between two correlations based on either independent or dependent groups. Dependent correlations can either be overlapping or nonoverlapping. A web interface is available on the website <http://comparingcorrelations.org>. A plugin for the R GUI and IDE RKWard is included. Please install RKWard from <https://rkward.kde.org> to use this feature. The respective R package rkward cannot be installed directly from a repository, as it is a part of RKWard.

Classification of climate according to Koeppen - Geiger, of aridity indices, of continentality indices, of water balance after Thornthwaite, of viticultural bioclimatic indices. Drawing climographs: Thornthwaite, Peguy, Bagnouls-Gaussen.

Wraps cytoscape.js as a shiny widget. cytoscape.js <https://js.cytoscape.org/> is a Javascript-based graph theory (network) library for visualization and analysis. This package supports the visualization of networks with custom visual styles and several available layouts. Demo Shiny applications are provided in the package code.

An R implementation of the Critical Path Method (CPM). CPM is a method used to estimate the minimum project duration and determine the amount of scheduling flexibility on the logical network paths within the schedule model. The flexibility is in terms of early start, early finish, late start, late finish, total float and free float. Beside, it permits to quantify the complexity of network diagram through the analysis of topological indicators. Finally, it permits to change the activities duration to perform what-if scenario analysis. The package was built based on following references: To make topological sorting and other graph operation, we use Csardi, G. & Nepusz, T. (2005) <https://www.researchgate.net/publication/221995787_The_Igraph_Software_Package_for_Complex_Network_Research>; For schedule concept, the reference was Project Management Institute (2017) <https://www.pmi.org/pmbok-guide-standards/foundational/pmbok>; For standards terms, we use Project Management Institute (2017) <https://www.pmi.org/pmbok-guide-standards/lexicon>; For algorithms on Critical Path Method development, we use Vanhoucke, M. (2013) <doi:10.1007/978-3-642-40438-2> and Vanhoucke, M. (2014) <doi:10.1007/978-3-319-04331-9>; And, finally, for topological definitions, we use Vanhoucke, M. (2009) <doi:10.1007/978-1-4419-1014-1>.

This package provides easy access to historical climate data in Canada from R. Search for weather stations and download raw hourly, daily or monthly weather data across Canada from 1840 to present. Implements public API access as detailed at <https://climate.weather.gc.ca>.

Defines the classes and functions used to simulate and to analyze data sets describing copy number variants and, optionally, sequencing mutations in order to detect clonal subsets. See Zucker et al. (2019) <doi:10.1093/bioinformatics/btz057>.

This package provides a shiny app to discover cocktails. The app allows one to search for cocktails by ingredient, filter on rating, and number of ingredients. The package also contains data with the ingredients of nearly 26 thousand cocktails scraped from the web.

Calculates confidence intervals after variable selection using repeated data splits. The package offers methods to address the challenges of post-selection inference, ensuring more accurate confidence intervals in models involving variable selection. The two main functions are lmps', which records the different models selected across multiple data splits as well as the corresponding coefficient estimates, and cips', which takes the lmps object as input to select variables and perform inferences using two types of voting.

This package implements the Cross-contribution Compensating Multiple standard Normalization (CCMN) method described in Redestig et al. (2009) Analytical Chemistry <doi:10.1021/ac901143w> and other normalization algorithms.

Hierarchical continuous (and discrete) time state space modelling, for linear and nonlinear systems measured by continuous variables, with limited support for binary data. The subject specific dynamic system is modelled as a stochastic differential equation (SDE) or difference equation, measurement models are typically multivariate normal factor models. Linear mixed effects SDE's estimated via maximum likelihood and optimization are the default. Nonlinearities, (state dependent parameters) and random effects on all parameters are possible, using either max likelihood / max a posteriori optimization (with optional importance sampling) or Stan's Hamiltonian Monte Carlo sampling. See <https://github.com/cdriveraus/ctsem/raw/master/vignettes/hierarchicalmanual.pdf> for details. See <https://osf.io/preprints/psyarxiv/4q9ex_v2> for a detailed tutorial. Priors may be used. For the conceptual overview of the hierarchical Bayesian linear SDE approach, see <https://www.researchgate.net/publication/324093594_Hierarchical_Bayesian_Continuous_Time_Dynamic_Modeling>. Exogenous inputs may also be included, for an overview of such possibilities see <https://www.researchgate.net/publication/328221807_Understanding_the_Time_Course_of_Interventions_with_Continuous_Time_Dynamic_Models> . <https://cdriver.netlify.app/> contains some tutorial blog posts.

Analyzing responses to check-all-that-apply survey items often requires data transformations and subjective decisions for combining categories. CATAcode contains tools for exploring response patterns, facilitating data transformations, applying a set of decision rules for coding responses, and summarizing response frequencies.

This package provides a dynamic programming algorithm for optimal clustering multidimensional data with sequential constraint. The algorithm minimizes the sum of squares of within-cluster distances. The sequential constraint allows only subsequent items of the input data to form a cluster. The sequential constraint is typically required in clustering data streams or items with time stamps such as video frames, GPS signals of a vehicle, movement data of a person, e-pen data, etc. The algorithm represents an extension of Ckmeans.1d.dp to multiple dimensional spaces. Similarly to the one-dimensional case, the algorithm guarantees optimality and repeatability of clustering. Method clustering.sc.dp() can find the optimal clustering if the number of clusters is known. Otherwise, methods findwithinss.sc.dp() and backtracking.sc.dp() can be used. See Szkaliczki, T. (2016) "clustering.sc.dp: Optimal Clustering with Sequential Constraint by Using Dynamic Programming" <doi: 10.32614/RJ-2016-022> for more information.

This package provides a simple package to grab cheat sheets and save them to your local computer.