This package provides an interface to the European Central Bank's Data Portal API, allowing for programmatic retrieval of a vast quantity of statistical data.

This package provides functions for estimating plant pathogen parameters from access period (AP) experiments. Separate functions are implemented for semi-persistently transmitted (SPT) and persistently transmitted (PT) pathogens. The common AP experiment exposes insect cohorts to infected source plants, healthy test plants, and intermediate plants (for PT pathogens). The package allows estimation of acquisition and inoculation rates during feeding, recovery rates, and latent progression rates (for PT pathogens). Additional functions support inference of epidemic risk from pathogen and local parameters, and also simulate AP experiment data. The functions implement probability models for epidemiological analysis, as derived in Donnelly et al. (2025), <doi:10.32942/X29K9P>. These models were originally implemented in the EpiPv GitHub package.

User friendly interface based on the R package gstat to fit exponential parametric models to empirical semi-variograms in order to model the spatial correlation structure of health data. Geo-located health outcomes of survey participants may be used to model spatial effects on health in an ego-centred approach. The package contains a range of functions to help explore the spatial structure of the data as well as visualize the fit of exponential models for various metaparameter combinations with respect to the number of lag intervals and maximal distance. Furthermore, the outcome of interest can be adjusted for covariates by fitting a linear regression in a preliminary step before the semi-variogram fitting process.

Evaluates the performance of binary classifiers. Computes confusion measures (TP, TN, FP, FN), derived measures (TPR, FDR, accuracy, F1, DOR, ..), and area under the curve. Outputs are well suited for nested dataframes.

This package provides easy access to tidy education finance data using Bellwether's methodology to combine NCES F-33 Survey, Census Bureau Small Area Income Poverty Estimates (SAIPE), and community data from the ACS 5-Year Estimates. The package simplifies downloading, caching, and filtering education finance data by year and state, enabling researchers and analysts to explore K-12 education funding patterns, revenue sources, expenditure categories, and demographic factors across U.S. school districts.

Generation of bioclimatic rasters that are complementary to the typical 19 bioclim variables.

The EvoPER, Evolutionary Parameter Estimation for Individual-based Models is an extensible package providing optimization driven parameter estimation methods using metaheuristics and evolutionary computation techniques (Particle Swarm Optimization, Simulated Annealing, Ant Colony Optimization for continuous domains, Tabu Search, Evolutionary Strategies, ...) which could be more efficient and require, in some cases, fewer model evaluations than alternatives relying on experimental design. Currently there are built in support for models developed with Repast Simphony Agent-Based framework (<https://repast.github.io/>) and with NetLogo (<https://www.netlogo.org/>) which are the most used frameworks for Agent-based modeling.

Provide an optimal histogram, in the sense of probability density estimation and features detection, by means of multiscale variational inference. In other words, the resulting histogram servers as an optimal density estimator, and meanwhile recovers the features, such as increases or modes, with both false positive and false negative controls. Moreover, it provides a parsimonious representation in terms of the number of blocks, which simplifies data interpretation. The only assumption for the method is that data points are independent and identically distributed, so it applies to fairly general situations, including continuous distributions, discrete distributions, and mixtures of both. For details see Li, Munk, Sieling and Walther (2016) <arXiv:1612.07216>.

Computes empirical Bayes confidence estimators and confidence intervals in a normal means model. The intervals are robust in the sense that they achieve correct coverage regardless of the distribution of the means. If the means are treated as fixed, the intervals have an average coverage guarantee. The implementation is based on Armstrong, Kolesár and Plagborg-Møller (2020) <arXiv:2004.03448>.

Analysis of elliptical tubes with applications in biological modeling. The package is based on the references: Taheri, M., Pizer, S. M., & Schulz, J. (2024) "The Mean Shape under the Relative Curvature Condition." Journal of Computational and Graphical Statistics <doi:10.1080/10618600.2025.2535600> and arXiv <doi:10.48550/arXiv.2404.01043>. Mohsen Taheri Shalmani (2024) "Shape Statistics via Skeletal Structures", PhD Thesis, University of Stavanger, Norway <doi:10.13140/RG.2.2.34500.23685>. Key features include constructing discrete elliptical tubes, calculating transformations, validating structures under the Relative Curvature Condition (RCC), computing means, and generating simulations. Supports intrinsic and non-intrinsic mean calculations and transformations, size estimation, plotting, and random sample generation based on a reference tube. The intrinsic approach relies on the interior path of the original non-convex space, incorporating the RCC, while the non-intrinsic approach uses a basic robotic arm transformation that disregards the RCC.

This package provides a system for calculating the optimal sampling effort, based on the ideas of "Ecological cost-benefit optimization" as developed by A. Underwood (1997, ISBN 0 521 55696 1). Data is obtained from simulated ecological communities with prep_data() which formats and arranges the initial data, and then the optimization follows the following procedure of four functions: (1) prep_data() takes the original dataset and creates simulated sets that can be used as a basis for estimating statistical power and type II error. (2) sim_beta() is used to estimate the statistical power for the different sampling efforts specified by the user. (3) sim_cbo() calculates then the optimal sampling effort, based on the statistical power and the sampling costs. Additionally, (4) scompvar() calculates the variation components necessary for (5) Underwood_cbo() to calculate the optimal combination of number of sites and samples depending on either an economic budget or on a desired statistical accuracy. Lastly, (6) plot_power() helps the user visualize the results of sim_beta().

Estimates linear panel event study models. Plots coefficients following the recommendations in Freyaldenhoven et al. (2021) <doi:10.3386/w29170>. Includes sup-t bands, testing for key hypotheses, least wiggly path through the Wald region. Allows instrumental variables estimation following Freyaldenhoven et al. (2019) <doi:10.1257/aer.20180609>.

Correlation chart of two set (x and y) of data. Using Quantiles. Visualize the effect of factor.

This package provides tools to fit Mixture Cure Rate models via the Expectation-Maximization (EM) algorithm, allowing for flexible link functions in the cure component and various survival distributions in the latency part. The package supports user-specified link functions, includes methods for parameter estimation and model diagnostics, and provides residual analysis tailored for cure models. The classical theory methods used are described in Berkson, J. and Gage, R. P. (1952) <doi:10.2307/2281318>, Dempster, A. P., Laird, N. M. and Rubin, D. B. (1977) <https://www.jstor.org/stable/2984875>, Bazán, J., Torres-Avilés, F., Suzuki, A. and Louzada, F. (2017)<doi:10.1002/asmb.2215>.

This package provides methods for working with dose-finding clinical trials. We provide implementations of many dose-finding clinical trial designs, including the continual reassessment method (CRM) by O'Quigley et al. (1990) <doi:10.2307/2531628>, the toxicity probability interval (TPI) design by Ji et al. (2007) <doi:10.1177/1740774507079442>, the modified TPI (mTPI) design by Ji et al. (2010) <doi:10.1177/1740774510382799>, the Bayesian optimal interval design (BOIN) by Liu & Yuan (2015) <doi:10.1111/rssc.12089>, EffTox by Thall & Cook (2004) <doi:10.1111/j.0006-341X.2004.00218.x>; the design of Wages & Tait (2015) <doi:10.1080/10543406.2014.920873>, and the 3+3 described by Korn et al. (1994) <doi:10.1002/sim.4780131802>. All designs are implemented with a common interface. We also offer optional additional classes to tailor the behaviour of all designs, including avoiding skipping doses, stopping after n patients have been treated at the recommended dose, stopping when a toxicity condition is met, or demanding that n patients are treated before stopping is allowed. By daisy-chaining together these classes using the pipe operator from magrittr', it is simple to tailor the behaviour of a dose-finding design so it behaves how the trialist wants. Having provided a flexible interface for specifying designs, we then provide functions to run simulations and calculate dose-paths for future cohorts of patients.

This package implements the hybrid framework for event prediction described in Fang & Zheng (2011, <doi:10.1016/j.cct.2011.05.013>). To estimate the survival function the event prediction is based on, a piecewise exponential hazard function is fit to the time-to-event data to infer the potential change points. Prior to the last identified change point, the survival function is estimated using Kaplan-Meier, and the tail after the change point is fit using piecewise exponential.

Some wrappers, functions and data sets for for spatial point pattern analysis (mainly based on spatstat'), used in the book "Introduccion al Analisis Espacial de Datos en Ecologia y Ciencias Ambientales: Metodos y Aplicaciones" and in the papers by De la Cruz et al. (2008) <doi:10.1111/j.0906-7590.2008.05299.x> and Olano et al. (2009) <doi:10.1051/forest:2008074>.

This package implements likelihood-based evidence ratios for unified reporting in classical statistical testing. The package reports effect estimates, uncertainty intervals, and likelihood ratios on the log 10 scale derived from a single statistical model. It applies to standard normal mean tests, contingency tables, and regression coefficients, and provides a direct evidential measure while retaining classical error guarantees. For the Evidence Ratio Reporting Standard see Lawless (2026) <doi:10.5281/zenodo.18261076>.

This package provides a set of extensions for the ergm package to fit weighted networks whose edge weights are counts. See Krivitsky (2012) <doi:10.1214/12-EJS696> and Krivitsky, Hunter, Morris, and Klumb (2023) <doi:10.18637/jss.v105.i06>.

Interactive labelling of scatter plots, volcano plots and Manhattan plots using a shiny and plotly interface. Users can hover over points to see where specific points are located and click points on/off to easily label them. Labels can be dragged around the plot to place them optimally. Plots can be exported directly to PDF for publication. For plots with large numbers of points, points can optionally be rasterized as a bitmap, while all other elements (axes, text, labels & lines) are preserved as vector objects. This can dramatically reduce file size for plots with millions of points such as Manhattan plots, and is ideal for publication.

This package provides a series of R functions that come in handy while working with metabarcoding data. The reasoning of doing this is to have the same functions we use all the time stored in a curated, reproducible way. In a way it is all about putting together the grammar of the tidyverse from Wickham et al.(2019) <doi:10.21105/joss.01686> with the functions we have used in community ecology compiled in packages like vegan from Dixon (2003) <doi:10.1111/j.1654-1103.2003.tb02228.x> and phyloseq McMurdie & Holmes (2013) <doi:10.1371/journal.pone.0061217>. The package includes functions to read sequences from FAST(A/Q) into a tibble ('fasta_reader and fastq_reader'), to process cutadapt Martin (2011) <doi:10.14806/ej.17.1.200> info-file output. When it comes to sequence counts across samples, the package works with the long format in mind (a three column tibble with Sample, Sequence and counts ), with functions to move from there to the wider format.

Comprehensive toolkit for addressing selection bias in binary disease models across diverse non-probability samples, each with unique selection mechanisms. It utilizes Inverse Probability Weighting (IPW) and Augmented Inverse Probability Weighting (AIPW) methods to reduce selection bias effectively in multiple non-probability cohorts by integrating data from either individual-level or summary-level external sources. The package also provides a variety of variance estimation techniques. Please refer to Kundu et al. <doi:10.48550/arXiv.2412.00228>.

This package provides a comprehensive toolkit for single-cell annotation with the CellMarker2.0 database (see Xia Li, Peng Wang, Yunpeng Zhang (2023) <doi: 10.1093/nar/gkac947>). Streamlines biological label assignment in single-cell RNA-seq data and facilitates transcriptomic analysis, including preparation of TCGA<https://portal.gdc.cancer.gov/> and GEO<https://www.ncbi.nlm.nih.gov/geo/> datasets, differential expression analysis and visualization of enrichment analysis results. Additional utility functions support various bioinformatics workflows. See Wei Cui (2024) <doi: 10.1101/2024.09.14.609619> for more details.

This package contains a collection of examples of evidence factors in observational studies from the book Replication and Evidence Factors in Observational Studies by Paul R. Rosenbaum (2021) <doi:10.1201/9781003039648>.