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Estimates the multi-level vector autoregression model on time-series data. Three network structures are obtained: temporal networks, contemporaneous networks and between-subjects networks.
Fits multivariate Ornstein-Uhlenbeck types of models to continues trait data from species related by a common evolutionary history. See K. Bartoszek, J, Pienaar, P. Mostad, S. Andersson, T. F. Hansen (2012) <doi:10.1016/j.jtbi.2012.08.005> and K. Bartoszek, and J. Tredgett Clarke, J. Fuentes-Gonzalez, V. Mitov, J. Pienaar, M. Piwczynski, R. Puchalka, K. Spalik, K. L. Voje (2024) <doi:10.1111/2041-210X.14376>. The suggested PCMBaseCpp package (which significantly speeds up the likelihood calculations) can be obtained from <https://github.com/venelin/PCMBaseCpp/>.
This package provides a comprehensive toolkit for missing person identification combining genetic and non-genetic evidence within a Bayesian framework. Computes likelihood ratios (LRs) for DNA profiles, biological sex, age, hair color, and birthdate evidence. Provides decision analysis tools including optimal LR thresholds, error rate calculations, and ROC curve visualization. Includes interactive Shiny applications for exploring evidence combinations. For methodological details see Marsico et al. (2023) <doi:10.1016/j.fsigen.2023.102891> and Marsico, Vigeland et al. (2021) <doi:10.1016/j.fsigen.2021.102519>.
Several functions for maximum likelihood estimation of various univariate and multivariate distributions. The list includes more than 100 functions for univariate continuous and discrete distributions, distributions that lie on the real line, the positive line, interval restricted, circular distributions. Further, multivariate continuous and discrete distributions, distributions for compositional and directional data, etc. Some references include Johnson N. L., Kotz S. and Balakrishnan N. (1994). "Continuous Univariate Distributions, Volume 1" <ISBN:978-0-471-58495-7>, Johnson, Norman L. Kemp, Adrianne W. Kotz, Samuel (2005). "Univariate Discrete Distributions". <ISBN:978-0-471-71580-1> and Mardia, K. V. and Jupp, P. E. (2000). "Directional Statistics". <ISBN:978-0-471-95333-3>.
Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) <doi:10.1093/bioinformatics/btt459> and Kiihl et al. (2019) <doi:10.1515/sagmb-2018-0031>.
Conducts and visualizes propensity score analysis for multilevel, or clustered data. Bryer & Pruzek (2011) <doi:10.1080/00273171.2011.636693>.
Computes a finite-sample tail bound for the log-likelihood ratio test (LRT) statistic under multinomial sampling. The resulting bound is used to compute finite-sample conservative p-values and critical values when the standard chi-squared asymptotics can be unreliable. The package also supports multiple independent multinomial trials.
This package provides a framework for analyzing broth microdilution assays in various 96-well plate designs, visualizing results and providing descriptive and (simple) inferential statistics (i.e. summary statistics and sign test). The functions are designed to add metadata to 8 x 12 tables of absorption values, creating a tidy data frame. Users can choose between clean-up procedures via function parameters (which covers most cases) or user prompts (in cases with complex experimental designs). Users can also choose between two validation methods, i.e. exclusion of absorbance values above a certain threshold or manual exclusion of samples. A function for visual inspection of samples with their absorption values over time for certain group combinations helps with the decision. In addition, the package includes functions to subtract the background absorption (usually at time T0) and to calculate the growth performance compared to a baseline. Samples can be visually inspected with their absorption values displayed across time points for specific group combinations. Core functions of this package (i.e. background subtraction, sample validation and statistics) were inspired by the manual calculations that were applied in Tewes and Muller (2020) <doi:10.1038/s41598-020-67600-7>.
Perform correlation and linear regression test among the numeric fields in a data.frame automatically and make plots using pairs or lattice::parallelplot.
Implementation of Multiple Comparison Procedures with Modeling (MCP-Mod) procedure with bias-corrected estimators and second-order covariance matrices as described in Diniz, Gallardo and Magalhaes (2023) <doi:10.1002/pst.2303>.
This package implements model-robust standardization for cluster-randomized trials (CRTs). Provides functions that standardize user-specified regression models to estimate marginal treatment effects. The targets include the cluster-average and individual-average treatment effects, with utilities for variance estimation and example simulation datasets. Methods are described in Li, Tong, Fang, Cheng, Kahan, and Wang (2025) <doi:10.1002/sim.70270>.
An implementation of Multi-Task Logistic Regression (MTLR) for R. This package is based on the method proposed by Yu et al. (2011) which utilized MTLR for generating individual survival curves by learning feature weights which vary across time. This model was further extended to account for left and interval censored data.
Local recombination rates are graphically estimated across a genome using Marey maps.
This package provides a toolkit for genomic selection in animal breeding with emphasis on multi-breed and multi-trait nested grouping operations. Streamlines iterative analysis workflows when working with ASReml-R package. Includes utility functions for phenotypic data processing commonly used by animal breeders.
This package performs variable selection in high-dimensional sparse GLARMA models. For further details we refer the reader to the paper Gomtsyan et al. (2022), <arXiv:2208.14721>.
Extract, transform and load MITRE standards. This package gives you an approach to cybersecurity data sets. All data sets are build on runtime downloading raw data from MITRE public services. MITRE <https://www.mitre.org/> is a government-funded research organization based in Bedford and McLean. Current version includes most used standards as data frames. It also provide a list of nodes and edges with all relationships.
Data and code for the paper by Ehm, Gneiting, Jordan and Krueger ('Of Quantiles and Expectiles: Consistent Scoring Functions, Choquet Representations, and Forecast Rankings', JRSS-B, 2016 <DOI:10.1111/rssb.12154>).
This will allow easier management of a CRAN-style repository on local networks (i.e. not on CRAN). This might be necessary where hosted packages contain intellectual property owned by a corporation.
This package provides various functions for parameter estimation of one-dimensional stable distributions and their mixtures. It implements a diverse set of estimation methods, including quantile-based approaches, regression methods based on the empirical characteristic function (empirical, kernel, and recursive), and maximum likelihood estimation. For mixture models, it provides stochastic expectationâ maximization (SEM) algorithms and Bayesian estimation methods using sampling and importance sampling to overcome the long burn-in period of Markov Chain Monte Carlo (MCMC) strategies. The package also includes tools and statistical tests for analyzing whether a dataset follows a stable distribution. Some of the implemented methods are described in Hajjaji, O., Manou-Abi, S. M., and Slaoui, Y. (2024) <doi:10.1080/02664763.2024.2434627>.
This package provides readers for easy and consistent importing of Mouse Genome Informatics (MGI) report files: <https://www.informatics.jax.org/downloads/reports/index.html>. These data are provided by Baldarelli RM, Smith CL, Ringwald M, Richardson JE, Bult CJ, Mouse Genome Informatics Group (2024) <doi:10.1093/genetics/iyae031>.
This package provides routines for multivariate measurement error correction. Includes procedures for linear, logistic and Cox regression models. Bootstrapped standard errors and confidence intervals can be obtained for corrected estimates.
It implements a new procedure of variable selection in the context of redundancy between explanatory variables, which holds true with high dimensional data (Grimonprez et al. (2023) <doi:10.18637/jss.v106.i03>).
The sample mean and standard deviation are two commonly used statistics in meta-analyses, but some trials use other summary statistics such as the median and quartiles to report the results. Therefore, researchers need to transform those information back to the sample mean and standard deviation. This package implemented sample mean estimators by Luo et al. (2016) <arXiv:1505.05687>, sample standard deviation estimators by Wan et al. (2014) <arXiv:1407.8038>, and the best linear unbiased estimators (BLUEs) of location and scale parameters by Yang et al. (2018, submitted) based on sample quantiles derived summaries in a meta-analysis.
This package provides a complete and dedicated analytical toolbox for quality control and diagnosis based on subject-related measurements of micro-RNA (miRNA) expressions. The package consists of a set of functions that allow to train, optimize and use a Bayesian classifier that relies on multiplets of measured miRNA expressions. The package also implements the quality control tools required to preprocess input datasets. In addition, the package provides a function to carry out a statistical analysis of miRNA expressions, which can give insights to improve the classifier's performance. The method implemented in the package was first introduced in L. Ricci, V. Del Vescovo, C. Cantaloni, M. Grasso, M. Barbareschi and M. A. Denti, "Statistical analysis of a Bayesian classifier based on the expression of miRNAs", BMC Bioinformatics 16:287, 2015 <doi:10.1186/s12859-015-0715-9>. The package is thoroughly described in M. Castelluzzo, A. Perinelli, S. Detassis, M. A. Denti and L. Ricci, "MiRNA-QC-and-Diagnosis: An R package for diagnosis based on MiRNA expression", SoftwareX 12:100569, 2020 <doi:10.1016/j.softx.2020.100569>. Please cite both these works if you use the package for your analysis. DISCLAIMER: The software in this package is for general research purposes only and is thus provided WITHOUT ANY WARRANTY. It is NOT intended to form the basis of clinical decisions. Please refer to the GNU General Public License 3.0 (GPLv3) for further information.