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Typical morphological profiling datasets have millions of cells and hundreds of features per cell. When working with this data, you must clean the data, normalize the features to make them comparable across experiments, transform the features, select features based on their quality, and aggregate the single-cell data, if needed. cytominer makes these steps fast and easy. Methods used in practice in the field are discussed in Caicedo (2017) <doi:10.1038/nmeth.4397>. An overview of the field is presented in Caicedo (2016) <doi:10.1016/j.copbio.2016.04.003>.
Plot confidence interval from the objects of statistical tests such as t.test(), var.test(), cor.test(), prop.test() and fisher.test() ('htest class), Tukey test [TukeyHSD()], Dunnett test [glht() in multcomp package], logistic regression [glm()], and Tukey or Games-Howell test [posthocTGH() in userfriendlyscience package]. Users are able to set the styles of lines and points. This package contains the function to calculate odds ratios and their confidence intervals from the result of logistic regression.
Autosimilarity curves, standardization of spatial extent, dissimilarity indexes that overweight rare species, phylogenetic and functional (pairwise and multisample) dissimilarity indexes and nestedness for phylogenetic, functional and other diversity metrics. The methods for phylogenetic and functional nestedness is described in Melo, Cianciaruso and Almeida-Neto (2014) <doi:10.1111/2041-210X.12185>. This should be a complement to available packages, particularly vegan'.
This package contains functions to estimate the Correlation-Adjusted Regression Survival (CARS) Scores. The method is described in Welchowski, T. and Zuber, V. and Schmid, M., (2018), Correlation-Adjusted Regression Survival Scores for High-Dimensional Variable Selection, <arXiv:1802.08178>.
This package contains functions for testing for significant differences between multiple coefficients of variation. Includes Feltz and Miller's (1996) <DOI:10.1002/(SICI)1097-0258(19960330)15:6%3C647::AID-SIM184%3E3.0.CO;2-P> asymptotic test and Krishnamoorthy and Lee's (2014) <DOI:10.1007/s00180-013-0445-2> modified signed-likelihood ratio test. See the vignette for more, including full details of citations.
While data from randomized experiments remain the gold standard for causal inference, estimation of causal estimands from observational data is possible through various confounding adjustment methods. However, the challenge of unmeasured confounding remains a concern in causal inference, where failure to account for unmeasured confounders can lead to biased estimates of causal estimands. Sensitivity analysis within the framework of causal inference can help adjust for possible unmeasured confounding. In `causens`, three main methods are implemented: adjustment via sensitivity functions (Brumback, Hernán, Haneuse, and Robins (2004) <doi:10.1002/sim.1657> and Li, Shen, Wu, and Li (2011) <doi:10.1093/aje/kwr096>), Bayesian parametric modelling and Monte Carlo approaches (McCandless, Lawrence C and Gustafson, Paul (2017) <doi:10.1002/sim.7298>).
This package provides methods for difference-in-differences with a continuous treatment and staggered treatment adoption. Includes estimation of treatment effects and causal responses as a function of the dose, event studies indexed by length of exposure to the treatment, and aggregation into overall average effects. Uniform inference procedures are included, along with both parametric and nonparametric models for treatment effects. The methods are based on Callaway, Goodman-Bacon, and Sant'Anna (2025) <doi:10.48550/arXiv.2107.02637>.
Bayesian fit of a Dirichlet Process Mixture with hierarchical multivariate skew normal kernels and coarsened posteriors. For more information, see Gorsky, Chan and Ma (2020) <arXiv:2001.06451>.
Assesses the quality of estimates made by complex sample designs, following the methodology developed by the National Institute of Statistics Chile (Household Survey Standard 2020, <https://www.ine.cl/docs/default-source/institucionalidad/buenas-pr%C3%A1cticas/clasificaciones-y-estandares/est%C3%A1ndar-evaluaci%C3%B3n-de-calidad-de-estimaciones-publicaci%C3%B3n-27022020.pdf>), (Economics Survey Standard 2024, <https://www.ine.gob.cl/docs/default-source/buenas-practicas/directrices-metodologicas/estandares/documentos/est%C3%A1ndar-evaluaci%C3%B3n-de-calidad-de-estimaciones-econ%C3%B3micas.pdf?sfvrsn=201fbeb9_2>) and by Economic Commission for Latin America and Caribbean (2020, <https://repositorio.cepal.org/bitstream/handle/11362/45681/1/S2000293_es.pdf>), (2024, <https://repositorio.cepal.org/server/api/core/bitstreams/f04569e6-4f38-42e7-a32b-e0b298e0ab9c/content>).
Price credit default swaps using C code from the International Swaps and Derivatives Association CDS Standard Model. See <https://www.cdsmodel.com/cdsmodel/documentation.html> for more information about the model and <https://www.cdsmodel.com/cdsmodel/cds-disclaimer.html> for license details for the C code.
This package performs the colocalisation tests described in Giambartolomei et al (2013) <doi:10.1371/journal.pgen.1004383>, Wallace (2020) <doi:10.1371/journal.pgen.1008720>, Wallace (2021) <doi:10.1371/journal.pgen.1009440>.
Implementations of canonical associative learning models, with tools to run experiment simulations, estimate model parameters, and compare model representations. Experiments and results are represented using S4 classes and methods.
An engine for stochastic cellular automata. It provides a high-level interface to declare a model, which can then be simulated by various backends (Genin et al. (2023) <doi:10.1101/2023.11.08.566206>).
Connect to the California Irrigation Management Information System (CIMIS) Web API. See the CIMIS main page <https://cimis.water.ca.gov> and web API documentation <https://et.water.ca.gov> for more information.
Mapas terrestres con topologias simplificadas. Estos mapas no tienen precision geodesica, por lo que aplica el DFL-83 de 1979 de la Republica de Chile y se consideran referenciales sin validez legal. No se incluyen los territorios antarticos y bajo ningun evento estos mapas significan que exista una cesion u ocupacion de territorios soberanos en contra del Derecho Internacional por parte de Chile. Esta paquete esta documentado intencionalmente en castellano asciificado para que funcione sin problema en diferentes plataformas. (Terrestrial maps with simplified toplogies. These maps lack geodesic precision, therefore DFL-83 1979 of the Republic of Chile applies and are considered to have no legal validity. Antartic territories are excluded and under no event these maps mean there is a cession or occupation of sovereign territories against International Laws from Chile. This package was intentionally documented in asciified spanish to make it work without problem on different platforms.).
This package provides methods to help selecting General Circulation Models (GCMs) in the context of projecting models to future scenarios. It is provided clusterization algorithms, distance and correlation metrics, as well as a tailor-made algorithm to detect the optimum subset of GCMs that recreate the environment of all GCMs as proposed in Esser et al. (2025) <doi:10.1111/gcb.70008>.
Cure dependent censoring regression models for long-term survival multivariate data. These models are based on extensions of the frailty models, capable to accommodating the cure fraction and the dependence between failure and censoring times, with Weibull and piecewise exponential marginal distributions. Theoretical details regarding the models implemented in the package can be found in Schneider et al. (2022) <doi:10.1007/s10651-022-00549-0>.
Implementation of the Wilkinson and Ivany (2002) approach to paleoclimate analysis, applied to isotope data extracted from clams.
Calculate the distribution of costs for the installation of an elevator based on the different distribution rules.
Fork of calendR R package to generate ready to print calendars with ggplot2 (see <https://r-coder.com/calendar-plot-r/>) with additional features (backwards compatible). calendRio provides a calendR() function that serves as a drop-in replacement for the upstream version but allows for additional parameters unlocking extra functionality.
This package provides functions for estimating and reporting multi-year averages and corresponding confidence intervals and distributions. A potential use case is reporting the chemical and ecological status of surface waters according to the European Water Framework Directive.
Duplicated publication data (pre-processed and formatted) for entity resolution. This data set contains a total of 1879 records. The following variables are included in the data set: id, title, book title, authors, address, date, year, editor, journal, volume, pages, publisher, institution, type, tech, note. The data set has a respective gold data set that provides information on which records match based on id.
This package provides a set of radiative transfer models to quantitatively describe the absorption, reflectance and transmission of solar energy in vegetation, and model remotely sensed spectral signatures of vegetation at distinct spatial scales (leaf,canopy and stand). The main principle behind ccrtm is that many radiative transfer models can form a coupled chain, basically models that feed into each other in a linked chain (from leaf, to canopy, to stand, to atmosphere). It allows the simulation of spectral datasets in the solar spectrum (400-2500nm) using leaf models as PROSPECT5, 5b, and D which can be coupled with canopy models as FLIM', SAIL and SAIL2'. Currently, only a simple atmospheric model ('skyl') is implemented. Jacquemoud et al 2008 provide the most comprehensive overview of these models <doi:10.1016/j.rse.2008.01.026>.
This package provides function declarations and inline function definitions that facilitate communication between R and the Eigen C++ library for linear algebra and scientific computing.