This package provides a backward-pipe operator for magrittr (%<%) or pipeR (%<<%) that allows for a performing operations from right-to-left. This allows writing more legible code where right-to-left ordering is natural. This is common with hierarchies and nested structures such as trees, directories or markup languages (e.g. HTML and XML). The package also includes a R-Studio add-in that can be bound to a keyboard shortcut.

Implementation of the Generalized Pairwise Comparisons (GPC) as defined in Buyse (2010) <doi:10.1002/sim.3923> for complete observations, and extended in Peron (2018) <doi:10.1177/0962280216658320> to deal with right-censoring. GPC compare two groups of observations (intervention vs. control group) regarding several prioritized endpoints to estimate the probability that a random observation drawn from one group performs better/worse/equivalently than a random observation drawn from the other group. Summary statistics such as the net treatment benefit, win ratio, or win odds are then deduced from these probabilities. Confidence intervals and p-values are obtained based on asymptotic results (Ozenne 2021 <doi:10.1177/09622802211037067>), non-parametric bootstrap, or permutations. The software enables the use of thresholds of minimal importance difference, stratification, non-prioritized endpoints (O Brien test), and can handle right-censoring and competing-risks.

This package performs CACE (Complier Average Causal Effect analysis) on either a single study or meta-analysis of datasets with binary outcomes, using either complete or incomplete noncompliance information. Our package implements the Bayesian methods proposed in Zhou et al. (2019) <doi:10.1111/biom.13028>, which introduces a Bayesian hierarchical model for estimating CACE in meta-analysis of clinical trials with noncompliance, and Zhou et al. (2021) <doi:10.1080/01621459.2021.1900859>, with an application example on Epidural Analgesia.

Bayesian analysis for stochastic extensions of non-linear dynamic systems using advanced computational algorithms. Described in Bouranis, L., Demiris, N., Kalogeropoulos, K., and Ntzoufras, I. (2022) <doi:10.48550/arXiv.2211.15229>.

BRIC-seq is a genome-wide approach for determining RNA stability in mammalian cells. This package provides a series of functions for performing quality check of your BRIC-seq data, calculation of RNA half-life for each transcript and comparison of RNA half-lives between two conditions.

Parse and read the files that comply with the brain imaging data structure, or BIDS format, see the publication from Gorgolewski, K., Auer, T., Calhoun, V. et al. (2016) <doi:10.1038/sdata.2016.44>. Provides query functions to extract and check the BIDS entity information (such as subject, session, task, etc.) from the file paths and suffixes according to the specification. The package is developed and used in the reproducible analysis and visualization of intracranial electroencephalography, or RAVE', see Magnotti, J. F., Wang, Z., and Beauchamp, M. S. (2020) <doi:10.1016/j.neuroimage.2020.117341>; see citation("bidsr") for details and attributions.

Calculates a range of UK freshwater invertebrate biotic indices including BMWP, Whalley, WHPT, Habitat-specific BMWP, AWIC, LIFE and PSI.

Binomial Haar-Fisz transforms for Gaussianization as in Nunes and Nason (2009).

This package provides tools for sampling from the PolyaGamma distribution based on Polson, Scott, and Windle (2013) <doi:10.1080/01621459.2013.829001>. Useful for logistic regression.

Boldness-recalibration maximally spreads out probability predictions while maintaining a user specified level of calibration, facilitated the brcal() function. Supporting functions to assess calibration via Bayesian and Frequentist approaches, Maximum Likelihood Estimator (MLE) recalibration, Linear in Log Odds (LLO)-adjust via any specified parameters, and visualize results are also provided. Methodological details can be found in Guthrie & Franck (2024) <doi:10.1080/00031305.2024.2339266>.

Collection of utilities that improve using Databricks from R. Primarily functions that wrap specific Databricks APIs (<https://docs.databricks.com/api>), RStudio connection pane support, quality of life functions to make Databricks simpler to use.

This package provides methods for choosing the rank of an SVD (singular value decomposition) approximation via cross validation. The package provides both Gabriel-style "block" holdouts and Wold-style "speckled" holdouts. It also includes an implementation of the SVDImpute algorithm. For more information about Bi-cross-validation, see Owen & Perry's 2009 AoAS article (at <arXiv:0908.2062>) and Perry's 2009 PhD thesis (at <arXiv:0909.3052>).

Implementation of a statistical approach for estimating the joint health effects of multiple concurrent exposures, as described in Bobb et al (2015) <doi:10.1093/biostatistics/kxu058>.

Fully Bayesian Classification with a subset of high-dimensional features, such as expression levels of genes. The data are modeled with a hierarchical Bayesian models using heavy-tailed t distributions as priors. When a large number of features are available, one may like to select only a subset of features to use, typically those features strongly correlated with the response in training cases. Such a feature selection procedure is however invalid since the relationship between the response and the features has be exaggerated by feature selection. This package provides a way to avoid this bias and yield better-calibrated predictions for future cases when one uses F-statistic to select features.

This package performs the algorithm for time series clustering described in Nieto-Barajas and Contreras-Cristan (2014).

Retrieve and import data from the INKAR database (Indikatoren und Karten zur Raum- und Stadtentwicklung Datenbank, <https://www.inkar.de>) of the Federal Office for Building and Regional Planning (BBSR) in Bonn using their JSON API.

The main function generateDataset() processes a user-supplied .R file that contains metadata parameters in order to generate actual data. The metadata parameters have to be structured in the form of metadata objects, the format of which is outlined in the package vignette. This approach allows to generate artificial data in a transparent and reproducible manner.

Bayesian synthetic likelihood (BSL, Price et al. (2018) <doi:10.1080/10618600.2017.1302882>) is an alternative to standard, non-parametric approximate Bayesian computation (ABC). BSL assumes a multivariate normal distribution for the summary statistic likelihood and it is suitable when the distribution of the model summary statistics is sufficiently regular. This package provides a Metropolis Hastings Markov chain Monte Carlo implementation of four methods (BSL, uBSL, semiBSL and BSLmisspec) and two shrinkage estimators (graphical lasso and Warton's estimator). uBSL (Price et al. (2018) <doi:10.1080/10618600.2017.1302882>) uses an unbiased estimator to the normal density. A semi-parametric version of BSL (semiBSL, An et al. (2018) <arXiv:1809.05800>) is more robust to non-normal summary statistics. BSLmisspec (Frazier et al. 2019 <arXiv:1904.04551>) estimates the Gaussian synthetic likelihood whilst acknowledging that there may be incompatibility between the model and the observed summary statistic. Shrinkage estimation can help to decrease the number of model simulations when the dimension of the summary statistic is high (e.g., BSLasso, An et al. (2019) <doi:10.1080/10618600.2018.1537928>). Extensions to this package are planned. For a journal article describing how to use this package, see An et al. (2022) <doi:10.18637/jss.v101.i11>.

Consider an at-most-K-stage group sequential design with only an upper bound for the last analysis and non-binding lower bounds.With binary endpoint, two kinds of test can be applied, asymptotic test based on normal distribution and exact test based on binomial distribution. This package supports the computation of boundaries and conditional power for single-arm group sequential test with binary endpoint, via either asymptotic or exact test. The package also provides functions to obtain boundary crossing probabilities given the design.

Allows the user to apply the Bayes Linear approach to finite population with the Simple Random Sampling - BLE_SRS() - and the Stratified Simple Random Sampling design - BLE_SSRS() - (both without replacement), to the Ratio estimator (using auxiliary information) - BLE_Ratio() - and to categorical data - BLE_Categorical(). The Bayes linear estimation approach is applied to a general linear regression model for finite population prediction in BLE_Reg() and it is also possible to achieve the design based estimators using vague prior distributions. Based on Gonçalves, K.C.M, Moura, F.A.S and Migon, H.S.(2014) <https://www150.statcan.gc.ca/n1/en/catalogue/12-001-X201400111886>.

High performance principal component analysis routines that operate directly on bigmemory::big.matrix() objects. The package avoids materialising large matrices in memory by streaming data through BLAS and LAPACK kernels and provides helpers to derive scores, loadings, correlations, and contribution diagnostics, including utilities that stream results into bigmemory'-backed matrices for file-based workflows. Additional interfaces expose scalable singular value decomposition, robust PCA, and robust SVD algorithms so that users can explore large matrices while tempering the influence of outliers. Scalable principal component analysis is also implemented, Elgamal, Yabandeh, Aboulnaga, Mustafa, and Hefeeda (2015) <doi:10.1145/2723372.2751520>.

Calculate Bayesian marginal effects, average marginal effects, and marginal coefficients (also called population averaged coefficients) for models fit using the brms package including fixed effects, mixed effects, and location scale models. These are based on marginal predictions that integrate out random effects if necessary (see for example <doi:10.1186/s12874-015-0046-6> and <doi:10.1111/biom.12707>).

This package implements functions to update Bayesian Predictive Power Computations after not stopping a clinical trial at an interim analysis. Such an interim analysis can either be blinded or unblinded. Code is provided for Normally distributed endpoints with known variance, with a prominent example being the hazard ratio.

Primarily created as an easy and understanding way to do basic sequences surrounding the central dogma of molecular biology.