The statistical analysis of circular data using distributions based on symmetric Nonnegative Trigonometric Sums (NNTS). It includes functions to perform empirical analysis and estimate the parameters of density functions. Fernandez-Duran, J.J. and Gregorio-Dominguez, M.M. (2025), "Multimodal Symmetric Circular Distributions Based on Nonnegative Trigonometric Sums and a Likelihood Ratio Test for Reflective Symmetry", <doi:10.48550/arXiv.2412.19501>.

This package provides functions to perform the following analyses: i) inferring epistasis from RNAi double knockdown data; ii) identifying gene pairs of multiple mutation patterns; iii) assessing association between gene pairs and survival; and iv) calculating the smallworldness of a graph (e.g., a gene interaction network). Data and analyses are described in Wang, X., Fu, A. Q., McNerney, M. and White, K. P. (2014). Widespread genetic epistasis among breast cancer genes. Nature Communications. 5 4828. <doi:10.1038/ncomms5828>.

This package provides a finite mixture of Zero-Inflated Poisson (ZIP) models for analyzing criminal trajectories.

Fits hidden Markov models of discrete character evolution which allow different transition rate classes on different portions of a phylogeny. Beaulieu et al (2013) <doi:10.1093/sysbio/syt034>.

Core visualizations and summaries for the CRAN package database. The package provides comprehensive methods for cleaning up and organizing the information in the CRAN package database, for building package directives networks (depends, imports, suggests, enhances, linking to) and collaboration networks, producing package dependence trees, and for computing useful summaries and producing interactive visualizations from the resulting networks and summaries. The resulting networks can be coerced to igraph <https://CRAN.R-project.org/package=igraph> objects for further analyses and modelling.

Allows to generate colors from palettes defined in the colormap module of Node.js'. (see <https://github.com/bpostlethwaite/colormap> for more information). In total it provides 44 distinct palettes made from sequential and/or diverging colors. In addition to the pre defined palettes you can also specify your own set of colors. There are also scale functions that can be used with ggplot2'.

Cronbach's alpha and McDonald's omega are widely used reliability or internal consistency measures in social, behavioral and education sciences. Alpha is reported in nearly every study that involves measuring a construct through multiple test items. The package coefficientalpha calculates coefficient alpha and coefficient omega with missing data and non-normal data. Robust standard errors and confidence intervals are also provided. A test is also available to test the tau-equivalent and homogeneous assumptions. Since Version 0.5, the bootstrap confidence intervals were added.

This package provides functions for cost-sensitive multi-criteria ensemble selection (CSMES) (as described in De bock et al. (2020) <doi:10.1016/j.ejor.2020.01.052>) for cost-sensitive learning under unknown cost conditions.

Hierarchical continuous (and discrete) time state space modelling, for linear and nonlinear systems measured by continuous variables, with limited support for binary data. The subject specific dynamic system is modelled as a stochastic differential equation (SDE) or difference equation, measurement models are typically multivariate normal factor models. Linear mixed effects SDE's estimated via maximum likelihood and optimization are the default. Nonlinearities, (state dependent parameters) and random effects on all parameters are possible, using either max likelihood / max a posteriori optimization (with optional importance sampling) or Stan's Hamiltonian Monte Carlo sampling. See <https://github.com/cdriveraus/ctsem/raw/master/vignettes/hierarchicalmanual.pdf> for details. See <https://osf.io/preprints/psyarxiv/4q9ex_v2> for a detailed tutorial. Priors may be used. For the conceptual overview of the hierarchical Bayesian linear SDE approach, see <https://www.researchgate.net/publication/324093594_Hierarchical_Bayesian_Continuous_Time_Dynamic_Modeling>. Exogenous inputs may also be included, for an overview of such possibilities see <https://www.researchgate.net/publication/328221807_Understanding_the_Time_Course_of_Interventions_with_Continuous_Time_Dynamic_Models> . <https://cdriver.netlify.app/> contains some tutorial blog posts.

Plotting functions to create circular boxplots for grouped data. The primary 2-dimensional version creates concentric circular boxplots for specified groups, scaling the width of each boxplot to adjust for human perception. The 3-dimensional version maps these plots onto a torus which is suitable for periodic circular data such as wind direction over the course of a year. An example dataset of this type is provided for reference. For examples of circular boxplots and additional implementation details, see Berlinski et al. (2026) <doi:10.48550/arXiv.2602.05335>.

Is designed to test for association between methylation at CpG sites across the genome and a phenotype of interest, adjusting for any relevant covariates. The package can perform standard analyses of large datasets very quickly with no need to impute the data. It can also handle mixed effects models with chip or batch entering the model as a random intercept. Also includes tools to apply quality control filters, perform permutation tests, and create QQ plots, manhattan plots, and scatterplots for individual CpG sites.

Routines doing cone projection and quadratic programming, as well as doing estimation and inference for constrained parametric regression and shape-restricted regression problems. See Mary C. Meyer (2013)<doi:10.1080/03610918.2012.659820> for more details.

This package contains the Commercial Modular Aero-Propulsion System Simulation (C-MAPSS) data set.

Package for the analysis of categorical functional data. The main purpose is to compute an encoding (real functional variable) for each state <doi:10.3390/math9233074>. It also provides functions to perform basic statistical analysis on categorical functional data.

Obtain coordinate system metadata from various data formats. There are functions to extract a CRS (coordinate reference system, <https://en.wikipedia.org/wiki/Spatial_reference_system>) in EPSG (European Petroleum Survey Group, <http://www.epsg.org/>), PROJ4 <https://proj.org/>, or WKT2 (Well-Known Text 2, <http://docs.opengeospatial.org/is/12-063r5/12-063r5.html>) forms. This is purely for getting simple metadata from in-memory formats, please use other tools for out of memory data sources.

This package provides a compilation of tests for hypotheses regarding covariance and correlation matrices for one or more groups. The hypothesis can be specified through a corresponding hypothesis matrix and a vector or by choosing one of the basic hypotheses, while for the structure test, only the latter works. Thereby Monte-Carlo and Bootstrap-techniques are used, and the respective method must be chosen, and the functions provide p-values and mostly also estimators of calculated covariance matrices of test statistics. For more details on the methodology, see Sattler et al. (2022) <doi:10.1016/j.jspi.2021.12.001>, Sattler and Pauly (2024) <doi:10.1007/s11749-023-00906-6>, and Sattler and Dobler (2025) <doi:10.48550/arXiv.2310.11799>.

Access chemical, hazard, bioactivity, and exposure data from the Computational Toxicology and Exposure ('CTX') APIs <https://www.epa.gov/comptox-tools/computational-toxicology-and-exposure-apis>. ctxR was developed to streamline the process of accessing the information available through the CTX APIs without requiring prior knowledge of how to use APIs. Most data is also available on the CompTox Chemical Dashboard ('CCD') <https://comptox.epa.gov/dashboard/> and other resources found at the EPA Computational Toxicology and Exposure Online Resources <https://www.epa.gov/comptox-tools>.

Counts colors within color range(s) in images, and provides a masked version of the image with targeted pixels changed to a different color. Output includes the locations of the pixels in the images, and the proportion of the image within the target color range with optional background masking. Users can specify multiple color ranges for masking.

The data and meta data from Statistics Netherlands (<https://www.cbs.nl>) can be browsed and downloaded. The client uses the open data API of Statistics Netherlands.

Changing the name of an existing R package is annoying but common task especially in the early stages of package development. This package (mostly) automates this task.

This package provides functions to perform statistical inference of data organized in contingency tables. This package is a companion to the "Statistical Analysis of Contingency Tables" book by Fagerland et al. <ISBN 9781466588172>.

There are many estimators of false discovery rate. In this package we compute the Nonlocal False Discovery Rate (NFDR) and the estimators of local false discovery rate: Corrected False discovery Rate (CFDR), Re-ranked False Discovery rate (RFDR) and the blended estimator. Bickel, D.R., Rahal, A. (2019) <https://tinyurl.com/kkdc9rk8>.

Identifies clinically relevant concepts in Observational Medical Outcomes Partnership Common Data Model cohorts using an enrichment-based workflow. Defines target and control cohorts and extracts medical interventions that are over-represented in the target cohort during the observation period. Users can tune filtering and selection thresholds. The workflow includes chi-squared tests for two proportions with Yates continuity correction, logistic tests, and hierarchy and correlation mappings for relevant concepts. The results can be optionally explored using the bundled graphical user interface. For workflow details and examples, see <https://healthinformaticsut.github.io/CohortContrast/>.

Utility functions that provides wrapper to descriptive base functions like cor, mean and table. It makes use of the formula interface to pass variables to functions. It also provides operators to concatenate (%+%), to repeat (%n%) and manage character vectors for nice display.