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Compute energy landscapes using a digital elevation model and body mass of animals.
Fit Bayesian (hierarchical) cognitive models using a linear modeling language interface using particle Metropolis Markov chain Monte Carlo sampling with Gibbs steps. The diffusion decision model (DDM), linear ballistic accumulator model (LBA), racing diffusion model (RDM), and the lognormal race model (LNR) are supported. Additionally, users can specify their own likelihood function and/or choose for non-hierarchical estimation, as well as for a diagonal, blocked or full multivariate normal group-level distribution to test individual differences. Prior specification is facilitated through methods that visualize the (implied) prior. A wide range of plotting functions assist in assessing model convergence and posterior inference. Models can be easily evaluated using functions that plot posterior predictions or using relative model comparison metrics such as information criteria or Bayes factors. References: Stevenson et al. (2024) <doi:10.31234/osf.io/2e4dq>.
This package performs analysis of regression in simple designs with quantitative treatments, including mixed models and non linear models.
Pupillometry offers a non-invasive window into the mind and has been used extensively as a psychophysiological readout of arousal signals linked with cognitive processes like attention, stress, and emotional states [Clewett et al. (2020) <doi:10.1038/s41467-020-17851-9>; Kret & Sjak-Shie (2018) <doi:10.3758/s13428-018-1075-y>; Strauch (2024) <doi:10.1016/j.tins.2024.06.002>]. Yet, despite decades of pupillometry research, many established packages and workflows to date lack design patterns based on Findability, Accessibility, Interoperability, and Reusability (FAIR) principles [see Wilkinson et al. (2016) <doi:10.1038/sdata.2016.18>]. eyeris provides a modular, performant, and extensible preprocessing framework for pupillometry data with BIDS-like organization and interactive output reports [Esteban et al. (2019) <doi:10.1038/s41592-018-0235-4>; Gorgolewski et al. (2016) <doi:10.1038/sdata.2016.44>]. Development was supported, in part, by the Stanford Wu Tsai Human Performance Alliance, Stanford Ric Weiland Graduate Fellowship, Stanford Center for Mind, Brain, Computation and Technology, NIH National Institute on Aging Grants (R01-AG065255, R01-AG079345), NSF GRFP (DGE-2146755), McKnight Brain Research Foundation Clinical Translational Research Scholarship in Cognitive Aging and Age-Related Memory Loss, American Brain Foundation, and the American Academy of Neurology.
This package provides a tool to draw samples from a Empirical Likelihood Bayesian posterior of parameters using Hamiltonian Monte Carlo.
This package implements the methods of McGrath et al. (2020) <doi:10.1177/0962280219889080> and Cai et al. (2021) <doi:10.1177/09622802211047348> for estimating the sample mean and standard deviation from commonly reported quantiles in meta-analysis. These methods can be applied to studies that report the sample median, sample size, and one or both of (i) the sample minimum and maximum values and (ii) the first and third quartiles. The corresponding standard error estimators described by McGrath et al. (2023) <doi:10.1177/09622802221139233> are also included.
This package provides functions to extract and process data from the FDA Adverse Event Reporting System (FAERS). It facilitates the conversion of raw FAERS data published after 2014Q3 into structured formats for analysis. See Yang et al. (2022) <doi:10.3389/fphar.2021.772768> for related information.
This package provides tools to compute the neural fragility matrix from intracranial electrocorticographic (iEEG) recordings, enabling the analysis of brain dynamics during seizures. The package implements the method described by Li et al. (2017) <doi:10.23919/ACC.2017.7963378> and includes functions for data preprocessing ('Epoch'), fragility computation ('calcAdjFrag'), and visualization.
Maximum likelihood estimation of an extended class of row-column (RC) association models for two-dimensional contingency tables, which are formulated by a condition of reduced rank on a matrix of extended association parameters; see Forcina (2019) <arXiv:1910.13848>. These parameters are defined by choosing the logit type for the row and column variables among four different options and a transformation derived from suitable divergence measures.
The Australian Regulatory Guidelines for Prescription Medicines (ARGPM), guidance on "Stability testing for prescription medicines", recommends to predict the shelf life of chemically derived medicines from stability data by taking the worst case situation at batch release into account. Consequently, if a change over time is observed, a release limit needs to be specified. Finding a release limit and the associated shelf life is supported, as well as the standard approach that is recommended by guidance Q1E "Evaluation of stability data" from the International Council for Harmonisation (ICH).
Model-based clustering for paired data based on the regression of a mixture of Bayesian hierarchical models on covariates. Zhang et al. (2023) <doi:10.1186/s12859-023-05556-x>.
Uses data and constants to calculate potential evapotranspiration (PET) and actual evapotranspiration (AET) from 21 different formulations including Penman, Penman-Monteith FAO 56, Priestley-Taylor and Morton formulations.
Computes empirical Bayes confidence estimators and confidence intervals in a normal means model. The intervals are robust in the sense that they achieve correct coverage regardless of the distribution of the means. If the means are treated as fixed, the intervals have an average coverage guarantee. The implementation is based on Armstrong, Kolesár and Plagborg-Møller (2020) <arXiv:2004.03448>.
This package provides convenience functions for researching experiences including user, customer, patient, employee, and other human experiences. It provides a suite of tools to simplify data exploration such as benchmarking, comparing groups, and checking for differences. The outputs translate statistical approaches in applied experience research to human readable output.
This package provides a function (echo_find()) designed to find rhythms from data using extended harmonic oscillators. For more information, see H. De los Santos et al. (2020) <doi:10.1093/bioinformatics/btz617> .
This package provides a collection of functions developed to support the tutorial on using Exploratory Structural Equiation Modeling (ESEM) (Asparouhov & Muthén, 2009) <https://www.statmodel.com/download/EFACFA810.pdf>) with Longitudinal Study of Australian Children (LSAC) dataset (Mohal et al., 2023) <doi:10.26193/QR4L6Q>. The package uses tidyverse','psych', lavaan','semPlot and provides additional functions to conduct ESEM. The package provides general functions to complete ESEM, including esem_c(), creation of target matrix (if it is used) make_target(), generation of the Confirmatory Factor Analysis (CFA) model syntax esem_cfa_syntax(). A sample data is provided - the package includes a sample data of the Strengths and Difficulties Questionnaire of the Longitudinal Study of Australian Children (SDQ LSAC) in sdq_lsac(). ESEM package vignette presents the tutorial demonstrating the use of ESEM on SDQ LSAC data.
An extension of knitr that adds flexibility in several ways. One common source of frustration with knitr is that it assumes the directory where the source file lives should be the working directory, which is often not true. ezknitr addresses this problem by giving you complete control over where all the inputs and outputs are, and adds several other convenient features to make rendering markdown/HTML documents easier.
To run data analysis for enzyme-link immunosorbent assays (ELISAs). Either the five- or four-parameter logistic model will be fitted for data of single ELISA. Moreover, the batch effect correction/normalization will be carried out, when there are more than one batches of ELISAs. Feng (2018) <doi:10.1101/483800>.
Extends the ergm.multi packages from the Statnet suite to fit (temporal) exponential-family random graph models for signed networks. The framework models positive and negative ties as interdependent, which allows estimation and testing of structural balance theory. The package also includes options for descriptive summaries, visualization, and simulation of signed networks. See Krivitsky, Koehly, and Marcum (2020) <doi:10.1007/s11336-020-09720-7> and Fritz, C., Mehrl, M., Thurner, P. W., & Kauermann, G. (2025) <doi:10.1017/pan.2024.21>.
Fast and memory-less computation of the energy statistics related quantities for vectors and matrices. References include: Szekely G. J. and Rizzo M. L. (2014), <doi:10.1214/14-AOS1255>. Szekely G. J. and Rizzo M. L. (2023), <ISBN:9781482242744>. Tsagris M. and Papadakis M. (2025). <doi:10.48550/arXiv.2501.02849>.
Various Expectation-Maximization (EM) algorithms are implemented for item response theory (IRT) models. The package includes IRT models for binary and ordinal responses, along with dynamic and hierarchical IRT models with binary responses. The latter two models are fitted using variational EM. The package also includes variational network and text scaling models. The algorithms are described in Imai, Lo, and Olmsted (2016) <DOI:10.1017/S000305541600037X>.
Checks to see whether a supplied set of dice (their face values) are transitive, returning pair-win and group-roll win probabilities. Expected returns (mean magnitude of win/loss) are presented as well.
This is a package for exact Confidence Intervals for the difference between two independent or dependent proportions.
The top-performing ensemble-based Penalized Cox Regression (ePCR) framework developed during the DREAM 9.5 mCRPC Prostate Cancer Challenge <https://www.synapse.org/ProstateCancerChallenge> presented in Guinney J, Wang T, Laajala TD, et al. (2017) <doi:10.1016/S1470-2045(16)30560-5> is provided here-in, together with the corresponding follow-up work. While initially aimed at modeling the most advanced stage of prostate cancer, metastatic Castration-Resistant Prostate Cancer (mCRPC), the modeling framework has subsequently been extended to cover also the non-metastatic form of advanced prostate cancer (CRPC). Readily fitted ensemble-based model S4-objects are provided, and a simulated example dataset based on a real-life cohort is provided from the Turku University Hospital, to illustrate the use of the package. Functionality of the ePCR methodology relies on constructing ensembles of strata in patient cohorts and averaging over them, with each ensemble member consisting of a highly optimized penalized/regularized Cox regression model. Various cross-validation and other modeling schema are provided for constructing novel model objects.