Package takes frequencies of mutations as reported by high throughput sequencing data from cancer and fits a theoretical neutral model of tumour evolution. Package outputs summary statistics and contains code for plotting the data and model fits. See Williams et al 2016 <doi:10.1038/ng.3489> and Williams et al 2017 <doi:10.1101/096305> for further details of the method.

Nonparametric (and semiparametric) kernel methods that seamlessly handle a mix of continuous, unordered, and ordered factor data types. This package is a parallel implementation of the np package based on the MPI specification that incorporates the Rmpi package (Hao Yu <hyu@stats.uwo.ca>) with minor modifications and we are extremely grateful to Hao Yu for his contributions to the R community. We would like to gratefully acknowledge support from the Natural Sciences and Engineering Research Council of Canada (NSERC, <https://www.nserc-crsng.gc.ca/>), the Social Sciences and Humanities Research Council of Canada (SSHRC, <https://www.sshrc-crsh.gc.ca/>), and the Shared Hierarchical Academic Research Computing Network (SHARCNET, <https://sharcnet.ca/>). We would also like to acknowledge the contributions of the GNU GSL authors. In particular, we adapt the GNU GSL B-spline routine gsl_bspline.c adding automated support for quantile knots (in addition to uniform knots), providing missing functionality for derivatives, and for extending the splines beyond their endpoints.

Computes the probability density function, the cumulative density function, quantile function, random numbers and measures of inference for the following families exponentiated generalized gull alpha power family, exponentiated gull alpha powerfamily, gull alpha power family.

This package provides tools for 4D nucleome imaging. Quantitative analysis of the 3D nuclear landscape recorded with super-resolved fluorescence microscopy. See Volker J. Schmid, Marion Cremer, Thomas Cremer (2017) <doi:10.1016/j.ymeth.2017.03.013>.

Cross-Entropy optimisation of unconstrained deterministic and noisy functions illustrated in Rubinstein and Kroese (2004, ISBN: 978-1-4419-1940-3) through a highly flexible and customisable function which allows user to define custom variable domains, sampling distributions, updating and smoothing rules, and stopping criteria. Several built-in methods and settings make the package very easy-to-use under standard optimisation problems.

Downloads and reads data from Human Connectome Project <https://db.humanconnectome.org> using Amazon Web Services ('AWS') S3 buckets.

Noninferiority tests for difference in failure rates at a prespecified control rate or prespecified time. For details, see Fay and Follmann, 2016 <DOI:10.1177/1740774516654861>.

This package provides tools for estimating Receiver Operating Characteristic (ROC) curves, building confidence bands, comparing several curves both for dependent and independent data, estimating the cumulative-dynamic ROC curve in presence of censored data, and performing meta-analysis studies, among others.

This package implements the navigated weighting (NAWT) proposed by Katsumata (2020) <arXiv:2005.10998>, which improves the inverse probability weighting by utilizing estimating equations suitable for a specific pre-specified parameter of interest (e.g., the average treatment effects or the average treatment effects on the treated) in propensity score estimation. It includes the covariate balancing propensity score proposed by Imai and Ratkovic (2014) <doi:10.1111/rssb.12027>, which uses covariate balancing conditions in propensity score estimation. The point estimate of the parameter of interest as well as coefficients for propensity score estimation and their uncertainty are produced using the M-estimation. The same functions can be used to estimate average outcomes in missing outcome cases.

Collapse, partition, combine, fill gaps in and expand date/time ranges.

This package provides functions to flash your hue lights, or text yourself, from R. Designed to be used with long running scripts.

Assists actuaries and other insurance modellers in pricing, reserving and capital modelling for non-life insurance and reinsurance modelling. Provides functions that help model excess levels, capping and pure Incurred but not reported claims (pure IBNR). Includes capped mean, exposure curves and increased limit factor curves (ILFs) for LogNormal, Gamma, Pareto, Sliced LogNormal-Pareto and Sliced Gamma-Pareto distributions. Includes mean, probability density function (pdf), cumulative probability function (cdf) and inverse cumulative probability function for Sliced LogNormal-Pareto and Sliced Gamma-Pareto distributions. Includes calculating pure IBNR exposure with LogNormal and Gamma distribution for reporting delay. Includes three shiny tools, one to simulate insurance claims applying reinsurance structures, fit generalised linear models and fit claims frequency or severity distributions. Methods used in the package refer to Free for All by Yiannis Parizas (2023) <https://www.theactuary.com/2023/03/02/free-all>; Escaping the triangle by Yiannis Parizas (2019) <https://www.theactuary.com/features/2019/06/2019/06/05/escaping-triangle>; Take to excess by Yiannis Parizas (2019) <https://www.theactuary.com/features/2019/03/2019/03/06/taken-excess>.

An R wrapper for pulling data from the National Public Transport Access Nodes ('NaPTAN') API (<https://www.api.gov.uk/dft/national-public-transport-access-nodes-naptan-api/#national-public-transport-access-nodes-naptan-api>). This allows users to download NaPTAN transport information, for the full dataset, by ATCO region code, or by name of region.

It provides ensemble capabilities to supervised and unsupervised learning models predictions without using training labels. It decides the relative weights of the different models predictions by using best models predictions as response variable and rest of the mo. User can decide the best model, therefore, It provides freedom to user to ensemble models based on their design solutions.

Vector AutoRegressive (VAR) type models with tailored regularisation structures are provided to uncover network type structures in the data, such as influential time series (influencers). Currently the package implements the LISAR model from Zhang and Trimborn (2023) <doi:10.2139/ssrn.4619531>. The package automatically derives the required regularisation sequences and refines it during the estimation to provide the optimal model. The package allows for model optimisation under various loss functions such as Mean Squared Forecasting Error (MSFE), Akaike Information Criterion (AIC), and Bayesian Information Criterion (BIC). It provides a dedicated class, allowing for summary prints of the optimal model and a plotting function to conveniently analyse the optimal model via heatmaps.

This package provides a collection of common univariate bounded probability distributions transformed to the unbounded real line, for the purpose of increased MCMC efficiency.

Stacking arrays according to dimension names, subset-aware splitting and mapping of functions, intersecting along arbitrary dimensions, converting to and from data.frames, and many other helper functions.

This package provides a collection of data structures that represent volumetric brain imaging data. The focus is on basic data handling for 3D and 4D neuroimaging data. In addition, there are function to read and write NIFTI files and limited support for reading AFNI files.

This package provides a navigation menu to enable pipe-friendly data processing for hierarchical data structures. By activating the menu items, you can perform operations on each item while maintaining the overall structure in attributes.

Infer system functioning with empirical NETwork COMparisons. These methods are part of a growing paradigm in network science that uses relative comparisons of networks to infer mechanistic classifications and predict systemic interventions. They have been developed and applied in Langendorf and Burgess (2021) <doi:10.1038/s41598-021-99251-7>, Langendorf (2020) <doi:10.1201/9781351190831-6>, and Langendorf and Goldberg (2019) <doi:10.48550/arXiv.1912.12551>.

This package provides a function designed to estimate the minimal sample size required to attain a specific statistical power in the context of linear regression and logistic regression models through simulations.

This package provides functions to calculate estimates of intrinsic and extrinsic noise from the two-reporter single-cell experiment, as in Elowitz, M. B., A. J. Levine, E. D. Siggia, and P. S. Swain (2002) Stochastic gene expression in a single cell. Science, 297, 1183-1186. Functions implement multiple estimators developed for unbiasedness or min Mean Squared Error (MSE) in Fu, A. Q. and Pachter, L. (2016). Estimating intrinsic and extrinsic noise from single-cell gene expression measurements. Statistical Applications in Genetics and Molecular Biology, 15(6), 447-471.

This package provides a tool set for food information and dietary assessment. It uses food composition data from several reference databases, including: USDA (United States), CIQUAL (France), BEDCA (Spain), CNF (Canada) and STFCJ (Japan). NutrienTrackeR calculates the intake levels for both macronutrient and micronutrients, and compares them with the recommended dietary allowances (RDA). It includes a number of visualization tools, such as time series plots of nutrient intake, and pie-charts showing the main foods contributing to the intake level of a given nutrient. A shiny app exposing the main functionalities of the package is also provided.

We connect the multi-class Neyman-Pearson classification (NP) problem to the cost-sensitive learning (CS) problem, and propose two algorithms (NPMC-CX and NPMC-ER) to solve the multi-class NP problem through cost-sensitive learning tools. Under certain conditions, the two algorithms are shown to satisfy multi-class NP properties. More details are available in the paper "Neyman-Pearson Multi-class Classification via Cost-sensitive Learning" (Ye Tian and Yang Feng, 2021).