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Uses three different correlation coefficients to calculate measurement-level adequate correlations in a feature matrix: Pearson product-moment correlation coefficient, Intraclass correlation and Cramer's V.
This package provides a computationally efficient and statistically rigorous fast Kernel Machine method for multi-kernel analysis. The approach is based on a low-rank approximation to the nuisance effect kernel matrices. The algorithm is applicable to continuous, binary, and survival traits and is implemented using the existing single-kernel analysis software SKAT and coxKM'. coxKM can be obtained from <https://github.com/lin-lab/coxKM>.
This package performs dose assignment and trial simulation for the FBCRM (Fully Bayesian Continual Reassessment Method) and MFBCRM (Mixture Fully Bayesian Continual Reassessment Method) phase I clinical trial designs. These trial designs extend the Continual Reassessment Method (CRM) and Bayesian Model Averaging Continual Reassessment Method (BMA-CRM) by allowing the prior toxicity skeleton itself to be random, with posterior distributions obtained from Markov Chain Monte Carlo. On average, the FBCRM and MFBCRM methods outperformed the CRM and BMA-CRM methods in terms of selecting an optimal dose level across thousands of randomly generated simulation scenarios. Details on the methods and results of this simulation study are available on request, and the manuscript is currently under review.
An implementation of the two-sample multivariate Kolmogorov-Smirnov test described by Fasano and Franceschini (1987) <doi:10.1093/mnras/225.1.155>. This test evaluates the null hypothesis that two i.i.d. random samples were drawn from the same underlying probability distribution. The data can be of any dimension, and can be of any type (continuous, discrete, or mixed).
Estimates and provides inference for quantities that assess high dimensional mediation and potential surrogate markers including the direct effect of treatment, indirect effect of treatment, and the proportion of treatment effect explained by a surrogate/mediator; details are described in Zhou et al (2022) <doi:10.1002/sim.9352> and Zhou et al (2020) <doi:10.1093/biomet/asaa016>. This package relies on the optimization software MOSEK', <https://www.mosek.com>.
Application of the filtered monotonic polynomial (FMP) item response model to flexibly fit item response models. The package includes tools that allow the item response model to be build on any monotonic transformation of the latent trait metric, as described by Feuerstahler (2019) <doi:10.1007/s11336-018-9642-9>.
Shiny app for the fdapace package.
This is a method for Allele-specific DNA Copy Number Profiling using Next-Generation Sequencing. Given the allele-specific coverage at the variant loci, this program segments the genome into regions of homogeneous allele-specific copy number. It requires, as input, the read counts for each variant allele in a pair of case and control samples. For detection of somatic mutations, the case and control samples can be the tumor and normal sample from the same individual.
Use Rmarkdown First method to build your package. Start your package with documentation, functions, examples and tests in the same unique file. Everything can be set from the Rmarkdown template file provided in your project, then inflated as a package. Inflating the template copies the relevant chunks and sections in the appropriate files required for package development.
When fitting a set of linear regressions which have some same variables, we can separate the matrix and reduce the computation cost. This package aims to fit a set of repeated linear regressions faster. More details can be found in this blog Lijun Wang (2017) <https://stats.hohoweiya.xyz/regression/2017/09/26/An-R-Package-Fit-Repeated-Linear-Regressions/>.
This package implements the Mode Jumping Markov Chain Monte Carlo algorithm described in <doi:10.1016/j.csda.2018.05.020> and its Genetically Modified counterpart described in <doi:10.1613/jair.1.13047> as well as the sub-sampling versions described in <doi:10.1016/j.ijar.2022.08.018> for flexible Bayesian model selection and model averaging.
This package provides a collection of features, decomposition methods, statistical summaries and graphics functions for the analysing tidy time series data. The package name feasts is an acronym comprising of its key features: Feature Extraction And Statistics for Time Series.
This package contains functions for operations with fuzzy cognitive maps using t-norm and s-norm operators. T-norms and S-norms are described by Dov M. Gabbay and George Metcalfe (2007) <doi:10.1007/s00153-007-0047-1>. System indicators are described by Cox, Earl D. (1995) <isbn:1886801010>. Executable examples are provided in the "inst/examples" folder.
This package provides a compositional statistical framework for absolute proportion estimation between fractions in RNA sequencing data. FracFixR addresses the fundamental challenge in fractionated RNA-seq experiments where library preparation and sequencing depth obscure the original proportions of RNA fractions. It reconstructs original fraction proportions using non-negative linear regression, estimates the "lost" unrecoverable fraction, corrects individual transcript frequencies, and performs differential proportion testing between conditions. Supports any RNA fractionation protocol including polysome profiling, sub-cellular localization, and RNA-protein complex isolation.
This package provides a simple method to select the best model or best subset of variables using different types of data (binary, Gaussian or Poisson) and applying it in different contexts (parametric or non-parametric).
Shed light on black box machine learning models by the help of model performance, variable importance, global surrogate models, ICE profiles, partial dependence (Friedman J. H. (2001) <doi:10.1214/aos/1013203451>), accumulated local effects (Apley D. W. (2016) <doi:10.48550/arXiv.1612.08468>), further effects plots, interaction strength, and variable contribution breakdown (Gosiewska and Biecek (2019) <doi:10.48550/arXiv.1903.11420>). All tools are implemented to work with case weights and allow for stratified analysis. Furthermore, multiple flashlights can be combined and analyzed together.
Processing of large-in-memory/large-on disk rasters and spatial vectors using GRASS <https://grass.osgeo.org/>. Most functions in the terra package are recreated. Processing of medium-sized and smaller spatial objects will nearly always be faster using terra or sf', but for large-in-memory/large-on-disk objects, fasterRaster may be faster. To use most of the functions, you must have the stand-alone version (not the OSGeoW4 installer version) of GRASS 8.0 or higher.
Given a multivariate dataset and some knowledge about the dependencies between its features, it is customary to fit a statistical model to the features to infer parameters of interest. Such a procedure implicitly assumes that the sample is exchangeable. This package provides a flexible non-parametric test of this exchangeability assumption, allowing the user to specify the feature dependencies by hand as long as features can be grouped into disjoint independent sets. This package also allows users to test a dual hypothesis, which is, given that the sample is exchangeable, does a proposed grouping of the features into disjoint sets also produce statistically independent sets of features? See Aw, Spence and Song (2023) for the accompanying paper.
The fftab package stores Fourier coefficients in a tibble and allows their manipulation in various ways. Functions are available for converting between complex, rectangular ('re', im'), and polar ('mod', arg') representations, as well as for extracting components as vectors or matrices. Inputs can include vectors, time series, and arrays of arbitrary dimensions, which are restored to their original form when inverting the transform. Since fftab stores Fourier frequencies as columns in the tibble, many standard operations on spectral data can be easily performed using tidy packages like dplyr'.
The FastRCS algorithm of Vakili and Schmitt (2014) for robust fit of the multivariable linear regression model and outliers detection.
Create local, regional, and global explanations for any machine learning model with forward marginal effects. You provide a model and data, and fmeffects computes feature effects. The package is based on the theory in: C. A. Scholbeck, G. Casalicchio, C. Molnar, B. Bischl, and C. Heumann (2022) <doi:10.48550/arXiv.2201.08837>.
Construction, calculation and display of fault trees. Methods derived from Clifton A. Ericson II (2005, ISBN: 9780471739425) <DOI:10.1002/0471739421>, Antoine Rauzy (1993) <DOI:10.1016/0951-8320(93)90060-C>, Tim Bedford and Roger Cooke (2012, ISBN: 9780511813597) <DOI:10.1017/CBO9780511813597>, Nikolaos Limnios, (2007, ISBN: 9780470612484) <DOI: 10.1002/9780470612484>.
Perform factorial analysis with a menu and draw graphs interactively thanks to FactoMineR and a Shiny application.
Constructs and visualises trade-off functions for f-differential privacy (f-DP) as introduced by Dong et al. (2022) <doi:10.1111/rssb.12454>. Supports Gaussian differential privacy, the f-DP generalisation of (epsilon, delta)-differential privacy, and accepts user-specified optimal type I / type II errors from which the lower convex hull trade-off function is automatically constructed.