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Researchers have been using simulated data from a multivariate linear model to compare and evaluate different methods, ideas and models. Additionally, teachers and educators have been using a simulation tool to demonstrate and teach various statistical and machine learning concepts. This package helps users to simulate linear model data with a wide range of properties by tuning few parameters such as relevant latent components. In addition, a shiny app as an RStudio gadget gives users a simple interface for using the simulation function. See more on: Sæbø, S., Almøy, T., Helland, I.S. (2015) <doi:10.1016/j.chemolab.2015.05.012> and Rimal, R., Almøy, T., Sæbø, S. (2018) <doi:10.1016/j.chemolab.2018.02.009>.
Evolutionary reconstruction based on substitutions and insertion-deletion (indels) analyses in a distance-based framework as described in Muñoz-Pajares (2013) <doi:10.1111/2041-210X.12118>.
Monitoring reporting rates of subject-level clinical events (e.g. adverse events, protocol deviations) reported by clinical trial sites is an important aspect of risk-based quality monitoring strategy. Sites that are under-reporting or over-reporting events can be detected using bootstrap simulations during which patients are redistributed between sites. Site-specific distributions of event reporting rates are generated that are used to assign probabilities to the observed reporting rates. (Koneswarakantha 2024 <doi:10.1007/s43441-024-00631-8>).
The nonparametric trend and its derivatives in equidistant time series (TS) with short-memory stationary errors can be estimated. The estimation is conducted via local polynomial regression using an automatically selected bandwidth obtained by a built-in iterative plug-in algorithm or a bandwidth fixed by the user. A Nadaraya-Watson kernel smoother is also built-in as a comparison. With version 1.1.0, a linearity test for the trend function, forecasting methods and backtesting approaches are implemented as well. The smoothing methods of the package are described in Feng, Y., Gries, T., and Fritz, M. (2020) <doi:10.1080/10485252.2020.1759598>.
The <http://standartox.uni-landau.de> database offers cleaned, harmonized and aggregated ecotoxicological test data, which can be used for assessing effects and risks of chemical concentrations found in the environment.
This package provides routines for scoring behavioral questionnaires. Includes scoring procedures for the International Physical Activity Questionnaire (IPAQ) <http://www.ipaq.ki.se>. Compares physical functional performance to the age- and gender-specific normal ranges.
Fitting the full likelihood proportional hazards model and extracting the residuals.
This package provides a collection of functions that enable easy access and updating of a database of data over time. More specifically, the package facilitates type-2 history for data-warehouses and provides a number of Quality of life improvements for working on SQL databases with R. For reference see Ralph Kimball and Margy Ross (2013, ISBN 9781118530801).
Streamlined workflow from deconvolution of bulk RNA-seq data to downstream differential expression and gene-set enrichment analysis. Provide various visualization functions.
Collection of datasets from Sen & Srivastava: "Regression Analysis, Theory, Methods and Applications", Springer. Sources for individual data files are more fully documented in the book.
Data sets from Ramsey, F.L. and Schafer, D.W. (2013), "The Statistical Sleuth: A Course in Methods of Data Analysis (3rd ed)", Cengage Learning.
Calculates maximum likelihood estimate, exact and asymptotic confidence intervals, and exact and asymptotic goodness of fit p-values for concentration of infectious units from serial limiting dilution assays. This package uses the likelihood equation, exact goodness of fit p-values, and exact confidence intervals described in Meyers et al. (1994) <http://jcm.asm.org/content/32/3/732.full.pdf>. This software is also implemented as a web application through the Shiny R package <https://iupm.shinyapps.io/sldassay/>.
This package provides a sparse covariance estimator based on different thresholding operators.
An exact method for computing the Poisson-Binomial Distribution (PBD). The package provides a function for generating a random sample from the PBD, as well as two distinct approaches for computing the density, distribution, and quantile functions of the PBD. The first method uses direct-convolution, or a dynamic-programming approach which is numerically stable but can be slow for a large input due to its quadratic complexity. The second method is much faster on large inputs thanks to its use of Fast Fourier Transform (FFT) based convolutions. Notably in this case the package uses an exponential shift to practically guarantee the relative accuracy of the computation of an arbitrarily small tail of the PBD -- something that FFT-based methods often struggle with. This ShiftConvolvePoiBin method is described in Peres, Lee and Keich (2020) <arXiv:2004.07429> where it is also shown to be competitive with the fastest implementations for exactly computing the entire Poisson-Binomial distribution.
The sparseMatEst package provides functions for estimating sparse covariance and precision matrices with error control. A false positive rate is fixed corresponding to the probability of falsely including a matrix entry in the support of the estimator. It uses the binary search method outlined in Kashlak and Kong (2019) <arXiv:1705.02679> and in Kashlak (2019) <arXiv:1903.10988>.
Fast enrichment analysis for locally correlated statistics via circular permutations. The analysis can be performed at multiple significance thresholds for both primary and auxiliary data sets with efficient correction for multiple testing.
This package produces LaTeX code, HTML/CSS code and ASCII text for well-formatted tables that hold regression analysis results from several models side-by-side, as well as summary statistics.
This package provides tools for predicting ICU length of stay and assessing ICU efficiency. It is based on the methodologies proposed by Peres et al. (2022, 2023), which utilize data-driven approaches for modeling and validation, offering insights into ICU performance and patient outcomes. References: Peres et al. (2022)<https://pubmed.ncbi.nlm.nih.gov/35988701/>, Peres et al. (2023)<https://pubmed.ncbi.nlm.nih.gov/37922007/>. More information: <https://github.com/igor-peres/ICU-Length-of-Stay-Prediction>.
This package provides a facility to generate sliced (orthogonal) Latin hypercube designs with four and five slices. For details about sliced and orthogonal Latin hypercube designs, see Yang, J. F., Lin, C. D., Qian, P. Z., and Lin, D. K. (2013). "Construction of sliced orthogonal Latin hypercube designs". Statistica Sinica, 1117-1130, <doi:10.5705/ss.2012.037>.
Image Segmentation using Superpixels, Affinity Propagation and Kmeans Clustering. The R code is based primarily on the article "Image Segmentation using SLIC Superpixels and Affinity Propagation Clustering, Bao Zhou, International Journal of Science and Research (IJSR), 2013" <https://www.ijsr.net/archive/v4i4/SUB152869.pdf>.
This package implements methods for obtaining kernel density estimates subject to a variety of shape constraints (unimodality, bimodality, symmetry, tail monotonicity, bounds, and constraints on the number of inflection points). Enforcing constraints can eliminate unwanted waves or kinks in the estimate, which improves its subjective appearance and can also improve statistical performance. The main function scdensity() is very similar to the density() function in stats', allowing shape-restricted estimates to be obtained with little effort. The methods implemented in this package are described in Wolters and Braun (2017) <doi:10.1080/03610918.2017.1288247>, Wolters (2012) <doi:10.18637/jss.v047.i06>, and Hall and Huang (2002) <https://www3.stat.sinica.edu.tw/statistica/j12n4/j12n41/j12n41.htm>. See the scdensity() help for for full citations.
This package provides tools for the simultaneous improvement of multiple traits in plant breeding. Building upon the classical selection index (Smith 1937 <doi:10.1111/j.1469-1809.1936.tb02143.x>) and modern quantitative genetics (Kang 2020 <doi:10.1007/978-3-319-91223-3>), this package calculates classical phenotypic, genomic, marker-assisted, restricted/constrained, and eigen selection indices. It also incorporates multi-stage selection evaluation and stochastic simulations to estimate genetic advance based on economic weights, heritability, and genetic correlations.
This package provides functions are provided for the density function, distribution function, quantiles and random number generation for the skew hyperbolic t-distribution. There are also functions that fit the distribution to data. There are functions for the mean, variance, skewness, kurtosis and mode of a given distribution and to calculate moments of any order about any centre. To assess goodness of fit, there are functions to generate a Q-Q plot, a P-P plot and a tail plot.
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