This package performs regression analysis for longitudinal count data, allowing for serial dependence among observations from a given individual and two dimensional random effects on the linear predictor. Estimation is via maximization of the exact likelihood of a suitably defined model. Missing values and unbalanced data are allowed. Details can be found in the accompanying scientific papers: Goncalves & Cabral (2021, Journal of Statistical Software, <doi:10.18637/jss.v099.i03>) and Goncalves et al. (2007, Computational Statistics & Data Analysis, <doi:10.1016/j.csda.2007.03.002>).

This package implements a changepoint-aware ensemble forecasting algorithm that combines Theta, TBATS (Trigonometric, Box-Cox transformation, ARMA errors, Trend, Seasonal components), and ARFIMA (AutoRegressive, Fractionally Integrated, Moving Average) using a product-of-experts approach for robust probabilistic prediction.

Use optimal equal-HR method to determine two optimal cutpoints of a continuous predictor that has a U-shaped relationship with survival outcomes based on Cox regression model. The optimal equal-HR method estimates two optimal cut-points that have approximately the same log hazard value based on Cox regression model and divides individuals into different groups according to their HR values.

Clusters longitudinal trajectories over time (can be unequally spaced, unequal length time series and/or partially overlapping series) on a common time axis. Performs k-means clustering on a single continuous variable measured over time, where each mean is defined by a thin plate spline fit to all points in a cluster. Distance is MSE across trajectory points to cluster spline. Provides graphs of derived cluster splines, silhouette plots, and Adjusted Rand Index evaluations of the number of clusters. Scales well to large data with multicore parallelism available to speed computation.

Includes commands for bootstrapping and permutation tests, a command for created grouped bar plots, and a demo of the quantile-normal plot for data drawn from different distributions.

Classical cryptography methods for words and brief phrases. Substitution, transposition and concealment (null) ciphers are available, like Caesar, Vigenère, Atbash, affine, simple substitution, Playfair, rail fence, Scytale, single column, bifid, trifid, and Polybius ciphers.

This package provides a set of functions for applying a restricted linear algebra to the analysis of count-based data. See the accompanying preprint manuscript: "Normalizing need not be the norm: count-based math for analyzing single-cell data" Church et al (2022) <doi:10.1101/2022.06.01.494334> This tool is specifically designed to analyze count matrices from single cell RNA sequencing assays. The tools implement several count-based approaches for standard steps in single-cell RNA-seq analysis, including scoring genes and cells, comparing cells and clustering, calculating differential gene expression, and several methods for rank reduction. There are many opportunities for further optimization that may prove useful in the analysis of other data. We provide the source code freely available at <https://github.com/shchurch/countland> and encourage users and developers to fork the code for their own purposes.

Solves system of linear equations using (preconditioned) conjugate gradient algorithm, with improved efficiency using Armadillo templated C++ linear algebra library, and flexibility for user-specified preconditioning method. Please check <https://github.com/styvon/cPCG> for latest updates.

Package for CShapes 2.0, a GIS dataset of country borders (1886-today). Includes functions for data extraction and the computation of distance matrices and -lists.

This package provides a wrapper for the Clockify API <https://docs.clockify.me/>, making it possible to query, insert and update time keeping data.

This package provides functions for nonlinear regression parameters estimation by algorithms based on Controlled Random Search algorithm. Both functions (crs4hc(), crs4hce()) adapt current search strategy by four heuristics competition. In addition, crs4hce() improves adaptability by adaptive stopping condition.

Copula-based imputation methods: parametric and nonparametric algorithms for missing multivariate data through conditional copulas.

This package provides datasets containing preformatted maps of Norway at the county, municipality, and ward (Oslo only) level for redistricting in 2024, 2020, 2018, and 2017. Multiple layouts are provided (normal, split, and with an insert for Oslo), allowing the user to rapidly create choropleth maps of Norway without any geolibraries.

This package implements the Cross-contribution Compensating Multiple standard Normalization (CCMN) method described in Redestig et al. (2009) Analytical Chemistry <doi:10.1021/ac901143w> and other normalization algorithms.

This package provides an R interface to the Copernicus Marine Service for downloading and accessing marine data. Integrates with the official copernicusmarine Python library through reticulate'. Requires Python 3.7+ and a free Copernicus Marine account. See <https://marine.copernicus.eu/> and <https://pypi.org/project/copernicusmarine/> for more information.

Allows Brownian motion, fractional Brownian motion, and integrated Ornstein-Uhlenbeck process components to be added to linear and non-linear mixed effects models using the structures and methods of the nlme package.

This package provides a tool for matching ICD-10 codes to corresponding Clinical Classification Software Refined (CCSR) codes. The main function, CCSRfind(), identifies each CCSR code that applies to an individual given their diagnosis codes. It also provides a summary of CCSR codes that are matched to a dataset. The package contains 3 datasets: DXCCSR (mapping of ICD-10 codes to CCSR codes), Legend (conversion of DXCCSR to CCSRfind-usable format for CCSR codes with less than or equal to 1000 ICD-10 diagnosis codes), and LegendExtend (conversion of DXCCSR to CCSRfind-usable format for CCSR codes with more than 1000 ICD-10 dx codes). The disc() function applies grepl() ('base') to multiple columns and is used in CCSRfind().

An implementation of several functions for feature extraction in categorical time series datasets. Specifically, some features related to marginal distributions and serial dependence patterns can be computed. These features can be used to feed clustering and classification algorithms for categorical time series, among others. The package also includes some interesting datasets containing biological sequences. Practitioners from a broad variety of fields could benefit from the general framework provided by ctsfeatures'.

This package provides functions for making contour plots. The contour plot can be created from grid data, a function, or a data set. If non-grid data is given, then a Gaussian process is fit to the data and used to create the contour plot.

Surrounds the usual sample variance of a univariate numeric sample with a confidence interval for the population variance. This has been done so far only under the assumption that the underlying distribution is normal. Under the hood, this package implements the unique least-variance unbiased estimator of the variance of the sample variance, in a formula that is equivalent to estimating kurtosis and square of the population variance in an unbiased way and combining them according to the classical formula into an estimator of the variance of the sample variance. Both the sample variance and the estimator of its variance are U-statistics. By the theory of U-statistic, the resulting estimator is unique. See Fuchs, Krautenbacher (2016) <doi:10.1080/15598608.2016.1158675> and the references therein for an overview of unbiased estimation of variances of U-statistics.

Compute expected shortfall (ES) and Value at Risk (VaR) from a quantile function, distribution function, random number generator or probability density function. ES is also known as Conditional Value at Risk (CVaR). Virtually any continuous distribution can be specified. The functions are vectorized over the arguments. The computations are done directly from the definitions, see e.g. Acerbi and Tasche (2002) <doi:10.1111/1468-0300.00091>. Some support for GARCH models is provided, as well.

Various statistical methods for survival analysis in comparing survival curves between two groups, including overall hypothesis tests described in Li et al. (2015) <doi:10.1371/journal.pone.0116774> and Huang et al. (2020) <doi:10.1080/03610918.2020.1753075>, fixed-point tests in Klein et al. (2007) <doi:10.1002/sim.2864>, short-term tests, and long-term tests in Logan et al. (2008) <doi:10.1111/j.1541-0420.2007.00975.x>. Some commonly used descriptive statistics and plots are also included.

Interface to easily access Cropland Data Layer (CDL) data for any area of interest via the CropScape <https://nassgeodata.gmu.edu/CropScape/> web service.

The implementation of bias-corrected sandwich variance estimators for the analysis of cluster randomized trials with time-to-event outcomes using the marginal Cox model, proposed by Wang et al. (under review).