Concatenation of multiple sequence alignments based on a correspondence table that can be edited in Excel <doi:10.5281/zenodo.5130603>.

This package provides a copula based clustering algorithm that finds clusters according to the complex multivariate dependence structure of the data generating process. The updated version of the algorithm is described in Di Lascio, F.M.L. and Giannerini, S. (2019). "Clustering dependent observations with copula functions". Statistical Papers, 60, p.35-51. <doi:10.1007/s00362-016-0822-3>.

An end-to-end framework that enables users to implement various descriptive studies for a given set of target and outcome cohorts for data mapped to the Observational Medical Outcomes Partnership Common Data Model.

Create correlation heatmaps from a numeric matrix. Ensembl Gene ID row names can be converted to Gene Symbols using, e.g., BioMart. Optionally, data can be clustered and filtered by correlation, tree cutting and/or number of missing values. Genes of interest can be highlighted in the plot and correlation significance be indicated by asterisks encoding corresponding P-Values. Plot dimensions and label measures are adjusted automatically by default. The plot features rely on the heatmap.n2() function in the heatmapFlex package.

This package provides a chess program which allows the user to create a game, add moves, check for legal moves and game result, plot the board, take back, read and write FEN (Forsythâ Edwards Notation). A basic chess engine based on minimax is implemented.

Collective matrix factorization (CMF) finds joint low-rank representations for a collection of matrices with shared row or column entities. This code learns a variational Bayesian approximation for CMF, supporting multiple likelihood potentials and missing data, while identifying both factors shared by multiple matrices and factors private for each matrix. For further details on the method see Klami et al. (2014) <arXiv:1312.5921>. The package can also be used to learn Bayesian canonical correlation analysis (CCA) and group factor analysis (GFA) models, both of which are special cases of CMF. This is likely to be useful for people looking for CCA and GFA solutions supporting missing data and non-Gaussian likelihoods. See Klami et al. (2013) <https://research.cs.aalto.fi/pml/online-papers/klami13a.pdf> and Virtanen et al. (2012) <http://proceedings.mlr.press/v22/virtanen12.html> for details on Bayesian CCA and GFA, respectively.

Connectome Predictive Modelling (CPM) (Shen et al. (2017) <doi:10.1038/nprot.2016.178>) is a method to predict individual differences in behaviour from brain functional connectivity. cpmr provides a simple yet efficient implementation of this method.

Copula-based imputation methods: parametric and nonparametric algorithms for missing multivariate data through conditional copulas.

This package provides a set of utilities for matching products in different classification codes used in international trade research. It supports concordance between the Harmonized System (HS0, HS1, HS2, HS3, HS4, HS5, HS combined), the Standard International Trade Classification (SITC1, SITC2, SITC3, SITC4), the North American Industry Classification System (NAICS combined), as well as the Broad Economic Categories (BEC), the International Standard of Industrial Classification (ISIC), and the Standard Industrial Classification (SIC). It also provides code nomenclature/descriptions look-up, Rauch classification look-up (via concordance to SITC2), and trade elasticity look-up (via concordance to HS0 or SITC3 codes).

This package implements Competitive Adaptive Reweighted Sampling (CARS) algorithm for variable selection from high-dimensional dataset using Partial Least Squares (PLS) regression models. CARS algorithm iteratively applies the Monte Carlo sub-sampling and exponential variable elimination techniques to identify/select the most informative variables/features subjected to minimal cross-validated RMSE score. The implementation of CARS algorithm is inspired from the work of Li et al. (2009) <doi:10.1016/j.aca.2009.06.046>. This algorithm is widely applied in near-infrared (NIR), mid-infrared (MIR), hyperspectral chemometrics areas, etc.

Changing the name of an existing R package is annoying but common task especially in the early stages of package development. This package (mostly) automates this task.

This package provides a collection of tools to easily analyze clinical data, including functions for correlation analysis, and statistical testing. The package facilitates the integration of clinical metadata with other omics layers, enabling exploration of quantitative variables. It also includes the utility for frequency matching samples across a dataset based on patient variables.

API to the database of CRAN package downloads from the RStudio CRAN mirror'. The database itself is at <http://cranlogs.r-pkg.org>, see <https://github.com/r-hub/cranlogs.app> for the raw API'.

ClickHouse (<https://clickhouse.com/>) is an open-source, high performance columnar OLAP (online analytical processing of queries) database management system for real-time analytics using SQL. This DBI backend relies on the ClickHouse HTTP interface and support HTTPS protocol.

Core Hunter is a tool to sample diverse, representative subsets from large germplasm collections, with minimum redundancy. Such so-called core collections have applications in plant breeding and genetic resource management in general. Core Hunter can construct cores based on genetic marker data, phenotypic traits or precomputed distance matrices, optimizing one of many provided evaluation measures depending on the precise purpose of the core (e.g. high diversity, representativeness, or allelic richness). In addition, multiple measures can be simultaneously optimized as part of a weighted index to bring the different perspectives closer together. The Core Hunter library is implemented in Java 8 as an open source project (see <http://www.corehunter.org>).

This package provides a collection of functions to pre-process amplification curve data from polymerase chain reaction (PCR) or isothermal amplification reactions. Contains functions to normalize and baseline amplification curves, to detect both the start and end of an amplification reaction, several smoothers (e.g., LOWESS, moving average, cubic splines, Savitzky-Golay), a function to detect false positive amplification reactions and a function to determine the amplification efficiency. Quantification point (Cq) methods include the first (FDM) and second approximate derivative maximum (SDM) methods (calculated by a 5-point-stencil) and the cycle threshold method. Data sets of experimental nucleic acid amplification systems ('VideoScan HCU', capillary convective PCR (ccPCR)) and commercial systems are included. Amplification curves were generated by helicase dependent amplification (HDA), ccPCR or PCR. As detection system intercalating dyes (EvaGreen, SYBR Green) and hydrolysis probes (TaqMan) were used. For more information see: Roediger et al. (2015) <doi:10.1093/bioinformatics/btv205>.

This package provides a system for creating R Markdown reports with a sequential syntax.

This package provides tools for assessing data quality, performing exploratory analysis, and semi-automatic preprocessing of messy data with change tracking for integral dataset cleaning.

This package provides functions for fitting univariate linear regression models under Scale Mixtures of Skew-Normal (SMSN) distributions, considering left, right or interval censoring and missing responses. Estimation is performed via an EM-type algorithm. Includes selection criteria, sample generation and envelope. For details, see Gil, Y.A., Garay, A.M., and Lachos, V.H. (2025) <doi:10.1007/s10260-025-00797-x>.

Allows inferring gene regulatory networks with direct physical interactions from microarray expression data using C3NET.

Implementation of two-dimensional (2D) correlation analysis based on the Fourier-transformation approach described by Isao Noda (I. Noda (1993) <DOI:10.1366/0003702934067694>). Additionally there are two plot functions for the resulting correlation matrix: The first one creates colored 2D plots, while the second one generates 3D plots.

Compile inline C code and easily call with automatically generated wrapper functions. By allowing user-defined headers and compilation flags (preprocessor, compiler and linking flags) the user can configure optimization options and linking to third party libraries. Multiple functions may be defined in a single block of code - which may be defined in a string or a path to a source file.

Classification of climate according to Koeppen - Geiger, of aridity indices, of continentality indices, of water balance after Thornthwaite, of viticultural bioclimatic indices. Drawing climographs: Thornthwaite, Peguy, Bagnouls-Gaussen.

Wrapper around the Canadian Mortgage and Housing Corporation (CMHC) web interface. It enables programmatic and reproducible access to a wide variety of housing data from CMHC.