Calculate the risk of developing type 2 diabetes using risk prediction algorithms derived by ClinRisk'.

Compile R functions annotated with type and shape declarations for extremely fast performance and robust runtime type checking. Supports both just-in-time (JIT) and ahead-of-time (AOT) compilation. Compilation is performed by lowering R code to Fortran.

This package implements the Quantification Evidence Standard algorithm for computing Bayesian evidence sufficiency from binary evidence matrices. It provides posterior estimates, credible intervals, percentiles, and optional visual summaries. The method is universal, reproducible, and independent of any specific clinical or rule based framework. For details see The Quantitative Omics Epidemiology Group et al. (2025) <doi:10.64898/2025.12.02.25341503>.

Finding hidden clusters in structured data can be hindered by the presence of masking variables. If not detected, masking variables are used to calculate the overall similarities between units, and therefore the cluster attribution is more imprecise. The algorithm q-vars implements an optimization method to find the variables that most separate units between clusters. In this way, masking variables can be discarded from the data frame and the clustering is more accurate. Tests can be found in Benati et al.(2017) <doi:10.1080/01605682.2017.1398206>.

This package provides three Quarto website templates as an R project, which are commonly used by academics. Templates for personal websites and course/workshop websites are included, as well as a template with minimal content for customization.

This package implements the Quantile-on-Quantile (QQ) regression methodology developed by Sim and Zhou (2015) <doi:10.1016/j.jbankfin.2015.01.013>. QQ regression estimates the effect that quantiles of one variable have on quantiles of another, capturing the dependence between distributions. The package provides functions for QQ regression estimation, 3D surface visualization with MATLAB'-style color schemes ('Jet', Viridis', Plasma'), heatmaps, contour plots, and quantile correlation analysis. Uses quantreg for quantile regression and plotly for interactive visualizations. Particularly useful for examining relationships between financial variables, oil prices, and stock returns under different market conditions.

This package provides methods for detecting structural breaks, determining the number of breaks, and estimating break locations in linear quantile regression, using one or multiple quantiles, based on Qu (2008) and Oka and Qu (2011). Applicable to both time series and repeated cross-sectional data. The main function is rq.break(). . References for detailed theoretical and empirical explanations: . (1) Qu, Z. (2008). "Testing for Structural Change in Regression Quantiles." Journal of Econometrics, 146(1), 170-184 <doi:10.1016/j.jeconom.2008.08.006> . (2) Oka, T., and Qu, Z. (2011). "Estimating Structural Changes in Regression Quantiles." Journal of Econometrics, 162(2), 248-267 <doi:10.1016/j.jeconom.2011.01.005>.

Molecular descriptors and outcomes for several public domain data sets.

The Ensemble Quadratic and Affine Invariant Markov chain Monte Carlo algorithms provide an efficient way to perform Bayesian inference in difficult parameter space geometries. The Ensemble Quadratic Monte Carlo algorithm was developed by Militzer (2023) <doi:10.3847/1538-4357/ace1f1>. The Ensemble Affine Invariant algorithm was developed by Goodman and Weare (2010) <doi:10.2140/camcos.2010.5.65> and it was implemented in Python by Foreman-Mackey et al (2013) <doi:10.48550/arXiv.1202.3665>. The Quadratic Monte Carlo method was shown to perform better than the Affine Invariant method in the paper by Militzer (2023) <doi:10.3847/1538-4357/ace1f1> and the Quadratic Monte Carlo method is the default method used. The Chen-Shao Highest Posterior Density Estimation algorithm is used for obtaining credible intervals and the potential scale reduction factor diagnostic is used for checking the convergence of the chains.

Adds an LLM-powered chatbot to your shiny app, that can turn your users natural language questions into SQL queries that run against your data, and return the result as a reactive data frame. Use it to drive reactive calculations, visualizations, downloads, and more.

Helps to perform linear regression analysis by reducing manual effort. Reduces the independent variables based on specified p-value and Variance Inflation Factor (VIF) level.

This package provides a toolkit for analysis and visualization of data from fluorophore-assisted seed amplification assays, such as Real-Time Quaking-Induced Conversion (RT-QuIC) and Fluorophore-Assisted Protein Misfolding Cyclic Amplification (PMCA). QuICSeedR addresses limitations in existing software by automating data processing, supporting large-scale analysis, and enabling comparative studies of analysis methods. It incorporates methods described in Henderson et al. (2015) <doi:10.1099/vir.0.069906-0>, Li et al. (2020) <doi:10.1038/s41598-021-96127-8>, Rowden et al. (2023) <doi:10.3390/pathogens12020309>, Haley et al. (2013) <doi:10.1371/journal.pone.0081488>, and Mair and Wilcox (2020) <doi:10.3758/s13428-019-01246-w>. Please refer to the original publications for details.

Densitometric evaluation of the photo-archived quantitative thin-layer chromatography (TLC) plates.

Calculates the right-tail probability of quadratic forms of Gaussian variables using the skewness-kurtosis ratio matching method, modified Liu-Tang-Zhang method and Satterthwaite-Welch method. The technical details can be found in Hong Zhang, Judong Shen and Zheyang Wu (2020) <arXiv:2005.00905>.

This package provides several methods for computing the Quantile Treatment Effect (QTE) and Quantile Treatment Effect on the Treated (QTT). The main cases covered are (i) Treatment is randomly assigned, (ii) Treatment is as good as randomly assigned after conditioning on some covariates (also called conditional independence or selection on observables) using the methods developed in Firpo (2007) <doi:10.1111/j.1468-0262.2007.00738.x>, (iii) Identification is based on a Difference in Differences assumption (several varieties are available in the package e.g. Athey and Imbens (2006) <doi:10.1111/j.1468-0262.2006.00668.x> Callaway and Li (2019) <doi:10.3982/QE935>, Callaway, Li, and Oka (2018) <doi:10.1016/j.jeconom.2018.06.008>).

Extensions of ggplot2 Q-Q plot functionalities.

This package provides a tool that can be customized to aid in the clean up of ecological data collected using quadrats and can crop quadrats to ensure comparability between quadrats collected under different methodologies.

Computes noncompartmental pharmacokinetic parameters for drug concentration profiles. For each profile, data imputations and adjustments are made as necessary and basic parameters are estimated. Supports single dose, multi-dose, and multi-subject data. Supports steady-state calculations and various routes of drug administration. See ?qpNCA and vignettes. Methodology follows Rowland and Tozer (2011, ISBN:978-0-683-07404-8), Gabrielsson and Weiner (1997, ISBN:978-91-9765-100-4), and Gibaldi and Perrier (1982, ISBN:978-0824710422).

It will assist the user to find simple quadratic roots from any quadratic equation.

This package implements Q-Learning, a model-free form of reinforcement learning, described in work by Strehl, Li, Wiewiora, Langford & Littman (2006) <doi:10.1145/1143844.1143955>.

Estimation methods for optimal treatment regimes under three different criteria, namely marginal quantile, marginal mean, and mean absolute difference. For the first two criteria, both one-stage and two-stage estimation method are implemented. A doubly robust estimator for estimating the quantile-optimal treatment regime is also included.

Test whether equality and order constraints hold for all individuals simultaneously by comparing Bayesian mixed models through Bayes factors. A tutorial style vignette and a quickstart guide are available, via vignette("manual", "quid"), and vignette("quickstart", "quid") respectively. See Haaf and Rouder (2017) <doi:10.1037/met0000156>; Haaf, Klaassen and Rouder (2019) <doi:10.31234/osf.io/a4xu9>; and Rouder & Haaf (2021) <doi:10.5334/joc.131>.

Fits non-crossing regression quantiles as a function of linear covariates and multiple smooth terms, including varying coefficients, via B-splines with L1-norm difference penalties. Random intercepts and variable selection are allowed via the lasso penalties. The smoothing parameters are estimated as part of the model fitting, see Muggeo and others (2021) <doi:10.1177/1471082X20929802>. Monotonicity and concavity constraints on the fitted curves are allowed, see Muggeo and others (2013) <doi:10.1007/s10651-012-0232-1>, and also <doi:10.13140/RG.2.2.12924.85122> or <doi:10.13140/RG.2.2.29306.21445> some code examples.

Primarily, the qcv package computes key indices related to the Quantifying Construct Validity procedure (QCV; Westen & Rosenthal, 2003 <doi:10.1037/0022-3514.84.3.608>; see also Furr & Heuckeroth, in press). The qcv() function is the heart of the qcv package, but additional functions in the package provide useful ancillary information related to the QCV procedure.