This package provides methods for valuation of life insurance premiums and reserves (including variable-benefit and fractional coverage) based on "Actuarial Mathematics" by Bowers, H.U. Gerber, J.C. Hickman, D.A. Jones and C.J. Nesbitt (1997, ISBN: 978-0938959465), "Actuarial Mathematics for Life Contingent Risks" by Dickson, David C. M., Hardy, Mary R. and Waters, Howard R (2009) <doi:10.1017/CBO9780511800146> and "Life Contingencies" by Jordan, C. W (1952) <doi:10.1017/S002026810005410X>. It also contains functions for equivalent interest and discount rate calculation, present and future values of annuities, and loan amortization schedule.

Generate balanced factorial designs with crossed and nested random and fixed effects <https://github.com/mmrabe/designr>.

This package provides functions to quantify dominant clonal lineages from DNA barcoding time-series data. The package implements clustering of barcode lineage trajectories, based on the assumption that similar temporal dynamics indicate comparable relative fitness. It also identifies persistent clonal lineages across time points. Input data can include lineage frequency tables derived from chromosomal barcoding, mutational libraries, or CRISPR/Cas screens. For more details, see Gagné-Leroux et al. (2024) <doi:10.1101/2024.09.08.611892>.

This package provides functions for handling dates.

Make inference in a mixture of discrete Laplace distributions using the EM algorithm. This can e.g. be used for modelling the distribution of Y chromosomal haplotypes as described in [1, 2] (refer to the URL section).

This package provides a Scannerless GLR parser/parser generator. Note that GLR standing for "generalized LR", where L stands for "left-to-right" and R stands for "rightmost (derivation)". For more information see <https://en.wikipedia.org/wiki/GLR_parser>. This parser is based on the Tomita (1987) algorithm. (Paper can be found at <https://aclanthology.org/P84-1073.pdf>). The original dparser package documentation can be found at <https://dparser.sourceforge.net/>. This allows you to add mini-languages to R (like rxode2's ODE mini-language Wang, Hallow, and James 2015 <DOI:10.1002/psp4.12052>) or to parse other languages like NONMEM to automatically translate them to R code. To use this in your code, add a LinkingTo dparser in your DESCRIPTION file and instead of using #include <dparse.h> use #include <dparser.h>. This also provides a R-based port of the make_dparser <https://dparser.sourceforge.net/d/make_dparser.cat> command called mkdparser(). Additionally you can parse an arbitrary grammar within R using the dparse() function, which works on most OSes and is mainly for grammar testing. The fastest parsing, of course, occurs at the C level, and is suggested.

Testing and documenting code that communicates with remote databases can be painful. Although the interaction with R is usually relatively simple (e.g. data(frames) passed to and from a database), because they rely on a separate service and the data there, testing them can be difficult to set up, unsustainable in a continuous integration environment, or impossible without replicating an entire production cluster. This package addresses that by allowing you to make recordings from your database interactions and then play them back while testing (or in other contexts) all without needing to spin up or have access to the database your code would typically connect to.

Dependent censoring regression models for survival multivariate data. These models are based on extensions of the frailty models, capable to accommodating the dependence between failure and censoring times, with Weibull and piecewise exponential marginal distributions. Theoretical details regarding the models implemented in the package can be found in Schneider et al. (2019) <doi:10.1002/bimj.201800391>.

This package provides a collection of tests to analyze the causal direction of dependence in linear models (Wiedermann, W., & von Eye, A., 2025, ISBN: 9781009381390). The package includes functions to perform Direction Dependence Analysis for variable distributions, residual distributions, and independence properties of predictors and residuals in competing causal models. In addition, the package contains functions to test the causal direction of dependence in conditional models (i.e., models with interaction terms) For more information see <https://www.ddaproject.com>.

Collection of functions for fitting and interpreting distributed lag interaction models (DLIM). A DLIM regresses a scalar outcome on repeated measures of exposure and allows for modification by a continuous variable. Includes a dlim() function for fitting, predict() function for inference, and plotting functions for visualization. Details on methodology are described in Demateis et al. (2024) <doi:10.1002/env.2843>.

This package provides functions for comparing two data.frames against each other. The core functionality is to provide a detailed breakdown of any differences between two data.frames as well as providing utility functions to help narrow down the source of problems and differences.

Data package for dartR'. Provides data sets to run examples in dartR'. This was necessary due to the size limit imposed by CRAN'. The data in dartR.data is needed to run the examples provided in the dartR functions. All available data sets are either based on actual data (but reduced in size) and/or simulated data sets to allow the fast execution of examples and demonstration of the functions.

This package creates a Dumbbell Plot.

Differential partial correlation identification with the ridge and the fusion penalties.

Analyze and visualize the rhythmic behavior of animals using the degree of functional coupling (See Scheibe (1999) <doi:10.1076/brhm.30.2.216.1420>), compute and visualize harmonic power, actograms, average activity and diurnality index.

Post Global Financial Crisis derivatives reforms have lifted the veil off over-the-counter (OTC) derivative markets. Swap Execution Facilities (SEFs) and Swap Data Repositories (SDRs) now publish data on swaps that are traded on or reported to those facilities (respectively). This package provides you the ability to get this data from supported sources.

It provides the subset operator for dist objects and a function to compute medoid(s) that are fully parallelized leveraging the RcppParallel package. It also provides functions for package developers to easily implement their own parallelized dist() function using a custom C++'-based distance function.

Creating dendrochronological networks based on the similarity between tree-ring series or chronologies. The package includes various functions to compare tree-ring curves building upon the dplR package. The networks can be used to visualise and understand the relations between tree-ring curves. These networks are also very useful to estimate the provenance of wood as described in Visser (2021) <DOI:10.5334/jcaa.79> or wood-use within a structure/context/site as described in Visser and Vorst (2022) <DOI:10.1163/27723194-bja10014>.

This package provides the user with an interactive application which can be used to facilitate the planning of dose finding studies by applying the theory of optimal experimental design.

Intelligently assign samples to batches in order to reduce batch effects. Batch effects can have a significant impact on data analysis, especially when the assignment of samples to batches coincides with the contrast groups being studied. By defining a batch container and a scoring function that reflects the contrasts, this package allows users to assign samples in a way that minimizes the potential impact of batch effects on the comparison of interest. Among other functionality, we provide an implementation for OSAT score by Yan et al. (2012, <doi:10.1186/1471-2164-13-689>).

This package contains a single function dclust() for divisive hierarchical clustering based on recursive k-means partitioning (k = 2). Useful for clustering large datasets where computation of a n x n distance matrix is not feasible (e.g. n > 10,000 records). For further information see Steinbach, Karypis and Kumar (2000) <http://glaros.dtc.umn.edu/gkhome/fetch/papers/docclusterKDDTMW00.pdf>.

Designed for genomic and proteomic data analysis, enabling unbiased PubMed searching, protein interaction network visualization, and comprehensive data summarization. This package aims to help users identify novel targets within their data sets based on protein network interactions and publication precedence of target's association with research context based on literature precedence. Methods in this package are described in detail in: Douglas (Year) <to-be-added DOI or link to the preprint>. Key functionalities of this package also leverage methodologies from previous works, such as: - Szklarczyk et al. (2023) <doi:10.1093/nar/gkac1000> - Winter (2017) <doi:10.32614/RJ-2017-066>.

Estimates probabilistic phylogenetic Principal Component Analysis (PCA) and non-phylogenetic probabilistic PCA. Provides methods to implement alternative models of trait evolution including Brownian motion (BM), Ornstein-Uhlenbeck (OU), Early Burst (EB), and Pagel's lambda. Also provides flexible biplot functions.

The models of probability density functions are Gaussian or exponential distributions with polynomial correction terms. Using a maximum likelihood method, dsdp computes parameters of Gaussian or exponential distributions together with degrees of polynomials by a grid search, and coefficient of polynomials by a variant of semidefinite programming. It adopts Akaike Information Criterion for model selection. See a vignette for a tutorial and more on our Github repository <https://github.com/tsuchiya-lab/dsdp/>.