Facilitates local polynomial regression for state dependent covariates in state-space models. The functionality can also be used from C++ based model builder tools such as Rcpp'/'inline', TMB', or JAGS'.

Concatenation of multiple sequence alignments based on a correspondence table that can be edited in Excel <doi:10.5281/zenodo.5130603>.

This package provides functions for fitting univariate linear regression models under Scale Mixtures of Skew-Normal (SMSN) distributions, considering left, right or interval censoring and missing responses. Estimation is performed via an EM-type algorithm. Includes selection criteria, sample generation and envelope. For details, see Gil, Y.A., Garay, A.M., and Lachos, V.H. (2025) <doi:10.1007/s10260-025-00797-x>.

Perform bulk and cell type-specific expression quantitative trail loci mapping with our novel method (Little et al. (2023) <doi:10.1038/s41467-023-38795-w>).

Deconvolution of bulk RNA-Sequencing data into proportions of cells based on a reference single-cell RNA-Sequencing dataset using high-dimensional geometric methodology <doi:10.64898/2026.01.24.701240>.

This package provides the source and examples for James P. Howard, II, "Computational Methods for Numerical Analysis with R," <https://jameshoward.us/cmna/>, a book on numerical methods in R.

Implementation of cross-validation method for testing the forecasting accuracy of several multi-population mortality models. The family of multi-population includes several multi-population mortality models proposed through the actuarial and demography literature. The package includes functions for fitting and forecast the mortality rates of several populations. Additionally, we include functions for testing the forecasting accuracy of different multi-population models. References, <https://journal.r-project.org/articles/RJ-2025-018/>. Atance, D., Debon, A., and Navarro, E. (2020) <doi:10.3390/math8091550>. Bergmeir, C. & Benitez, J.M. (2012) <doi:10.1016/j.ins.2011.12.028>. Debon, A., Montes, F., & Martinez-Ruiz, F. (2011) <doi:10.1007/s13385-011-0043-z>. Lee, R.D. & Carter, L.R. (1992) <doi:10.1080/01621459.1992.10475265>. Russolillo, M., Giordano, G., & Haberman, S. (2011) <doi:10.1080/03461231003611933>. Santolino, M. (2023) <doi:10.3390/risks11100170>.

Interact with Condor from R via SSH connection. Files are first uploaded from user machine to submitter machine, and the job is then submitted from the submitter machine to Condor'. Functions are provided to submit, list, and download Condor jobs from R. Condor is an open source high-throughput computing software framework for distributed parallelization of computationally intensive tasks.

This package provides classes (S4) of circular-linear, symmetric copulas with corresponding methods, extending the copula package. These copulas are especially useful for modeling correlation in discrete-time movement data. Methods for density, (conditional) distribution, random number generation, bivariate dependence measures and fitting parameters using maximum likelihood and other approaches. The package also contains methods for visualizing movement data and copulas.

This package implements a class of univariate and multivariate spatial generalised linear mixed models for areal unit data, with inference in a Bayesian setting using Markov chain Monte Carlo (MCMC) simulation using a single or multiple Markov chains. The response variable can be binomial, Gaussian, multinomial, Poisson or zero-inflated Poisson (ZIP), and spatial autocorrelation is modelled by a set of random effects that are assigned a conditional autoregressive (CAR) prior distribution. A number of different models are available for univariate spatial data, including models with no random effects as well as random effects modelled by different types of CAR prior, including the BYM model (Besag et al., 1991, <doi:10.1007/BF00116466>) and Leroux model (Leroux et al., 2000, <doi:10.1007/978-1-4612-1284-3_4>). Additionally, a multivariate CAR (MCAR) model for multivariate spatial data is available, as is a two-level hierarchical model for modelling data relating to individuals within areas. Full details are given in the vignette accompanying this package. The initial creation of this package was supported by the Economic and Social Research Council (ESRC) grant RES-000-22-4256, and on-going development has been supported by the Engineering and Physical Science Research Council (EPSRC) grant EP/J017442/1, ESRC grant ES/K006460/1, Innovate UK / Natural Environment Research Council (NERC) grant NE/N007352/1 and the TB Alliance.

DNA copy number data evaluation using both their initial form (copy number as a noisy function of genomic position) and their approximation by a piecewise-constant function (segmentation), for the purpose of identifying genomic regions where the copy number differs from the norm.

As a chronomètre is a stopwatch', this package offers a simple stopwatch, and in particular one that can be shared with Python (using the corresponding package of the same name available via PyPi') such that both interpreters operate on the same object instance and shown in the demo file, as well as in the unit tests.

This package provides a spatially-aware cell clustering algorithm is provided with cluster significance assessment. It comprises four key modules: spatially-aware cell-gene co-embedding, cell clustering, signature gene identification, and cluster significant assessment. More details can be referred to Peng Xie, et al. (2025) <doi:10.1016/j.cell.2025.05.035>.

Expectation-Maximization (EM) algorithm for point estimation and variance estimation to the nonparametric maximum likelihood estimator (NPMLE) for logistic-Cox cure-rate model with left truncation and right- censoring. See Hou, Chambers and Xu (2017) <doi:10.1007/s10985-017-9415-2>.

This package provides functions for performing quick observations or evaluations of data, including a variety of ways to list objects by size, class, etc. The functions seqle and reverse.seqle mimic the base rle but can search for linear sequences. The function splatnd allows the user to generate zero-argument commands without the need for makeActiveBinding . Functions provided to convert from any base to any other base, and to find the n-th greatest max or n-th least min. In addition, functions which mimic Unix shell commands, including head', tail ,'pushd ,and popd'. Various other goodies included as well.

Images are cropped to a circle with a transparent background. The function takes a vector of images, either local or from a link, and circle crops the image. Paths to the cropped image are returned for plotting with ggplot2'. Also includes cropping to a hexagon, heart, parallelogram, and square.

Every research team have their own script for data management, statistics and most importantly hemodynamic indices. The purpose is to standardize scripts utilized in clinical research. The hemodynamic indices can be used in a long-format dataframe, and add both periods of interest (trigger-periods), and delete artifacts with deleter-files. Transfer function analysis (Claassen et al. (2016) <doi:10.1177/0271678X15626425>) and Mx (Czosnyka et al. (1996) <doi:10.1161/01.str.27.10.1829>) can be calculated using this package.

This package implements the count splitting methodology from Neufeld et al. (2022) <doi:10.1093/biostatistics/kxac047> and Neufeld et al. (2023) <arXiv:2307.12985>. Intended for turning a matrix of single-cell RNA sequencing counts, or similar count datasets, into independent folds that can be used for training/testing or cross validation. Assumes that the entries in the matrix are from a Poisson or a negative binomial distribution.

This package provides a consistent interface for connecting R to various data sources including file systems and databases. Designed for clinical research, connector streamlines access to ADAM', SDTM for example. It helps to deal with multiple data formats through a standardized API and centralized configuration.

Gather boxscore and play-by-play data from the Canadian Elite Basketball League (CEBL) <https://www.cebl.ca> to create a repository of basic and advanced statistics for teams and players.

Assignment of cell type labels to single-cell RNA sequencing (scRNA-seq) clusters is often a time-consuming process that involves manual inspection of the cluster marker genes complemented with a detailed literature search. This is especially challenging when unexpected or poorly described populations are present. The clustermole R package provides methods to query thousands of human and mouse cell identity markers sourced from a variety of databases.

This is a pedagogical package, designed to help students understanding convergence of random variables. It provides a way to investigate interactively various modes of convergence (in probability, almost surely, in law and in mean) of a sequence of i.i.d. random variables. Visualisation of simulated sample paths is possible through interactive plots. The approach is illustrated by examples and exercises through the function investigate', as described in Lafaye de Micheaux and Liquet (2009) <doi:10.1198/tas.2009.0032>. The user can study his/her own sequences of random variables.

This package provides similar functionality to Microsoft Excel CUMPRINC function <https://support.microsoft.com/en-us/office/cumprinc-function-94a4516d-bd65-41a1-bc16-053a6af4c04d>. Returns principal remaining at a given month, principal paid in a month, and accumulated principal paid at a given month based on original loan amount, monthly interest rate, and term of loan.

Several functions for working with mixed effects regression models for limited dependent variables. The functions facilitate post-estimation of model predictions or margins, and comparisons between model predictions for assessing or probing moderation. Additional helper functions facilitate model comparisons and implements simulation-based inference for model predictions of alternative-specific outcome models. See also, Melamed and Doan (2024, ISBN: 978-1032509518).