This package provides tools to assist in safely applying user generated objective and derivative function to optimization programs. These are primarily function minimization methods with at most bounds and masks on the parameters. Provides a way to check the basic computation of objective functions that the user provides, along with proposed gradient and Hessian functions, as well as to wrap such functions to avoid failures when inadmissible parameters are provided. Check bounds and masks. Check scaling or optimality conditions. Perform an axial search to seek lower points on the objective function surface. Includes forward, central and backward gradient approximation codes.

Create regression tables for publication. Currently supports lm', glm', survreg', and ivreg outputs.

Get operating characteristics of one-arm clinical trial designs for time-to-event endpoint through simulation and perform analysis with time-to-event data.

Social media sites often embed cards when links are shared, based on metadata in the Open Graph Protocol (<https://ogp.me/>). This supports extracting that metadata from a website. It further allows for the creation of tags to add to a website to support the Open Graph Protocol and provides a list of the standard tags and their required properties.

Density-based clustering methods are well adapted to the clustering of high-dimensional data and enable the discovery of core groups of various shapes despite large amounts of noise. This package provides a novel density-based cluster extraction method, OPTICS k-Xi, and a framework to compare k-Xi models using distance-based metrics to investigate datasets with unknown number of clusters. The vignette first introduces density-based algorithms with simulated datasets, then presents and evaluates the k-Xi cluster extraction method. Finally, the models comparison framework is described and experimented on 2 genetic datasets to identify groups and their discriminating features. The k-Xi algorithm is a novel OPTICS cluster extraction method that specifies directly the number of clusters and does not require fine-tuning of the steepness parameter as the OPTICS Xi method. Combined with a framework that compares models with varying parameters, the OPTICS k-Xi method can identify groups in noisy datasets with unknown number of clusters. Results on summarized genetic data of 1,200 patients are in Charlon T. (2019) <doi:10.13097/archive-ouverte/unige:161795>. A short video tutorial can be found at <https://www.youtube.com/watch?v=P2XAjqI5Lc4/>.

Fast, optimal, and reproducible clustering algorithms for circular, periodic, or framed data. The algorithms introduced here are based on a core algorithm for optimal framed clustering the authors have developed (Debnath & Song 2021) <doi:10.1109/TCBB.2021.3077573>. The runtime of these algorithms is O(K N log^2 N), where K is the number of clusters and N is the number of circular data points. On a desktop computer using a single processor core, millions of data points can be grouped into a few clusters within seconds. One can apply the algorithms to characterize events along circular DNA molecules, circular RNA molecules, and circular genomes of bacteria, chloroplast, and mitochondria. One can also cluster climate data along any given longitude or latitude. Periodic data clustering can be formulated as circular clustering. The algorithms offer a general high-performance solution to circular, periodic, or framed data clustering.

This package provides an interface to OpenCL, allowing R to leverage computing power of GPUs and other HPC accelerator devices.

This package provides details such as Morphine Equivalent Dose (MED), brand name and opioid content which are calculated of all oral opioids authorized for sale by Health Canada and the FDA based on their Drug Identification Number (DIN) or National Drug Code (NDC). MEDs are calculated based on recommendations by Canadian Institute for Health Information (CIHI) and Von Korff et al (2008) and information obtained from Health Canada's Drug Product Database's monthly data dump or FDA Daily database for Canadian and US databases respectively. Please note in no way should output from this package be a substitute for medical advise. All medications should only be consumed on prescription from a licensed healthcare provider.

Supports the analysis of Oceanographic data, including ADCP measurements, measurements made with argo floats, CTD measurements, sectional data, sea-level time series, coastline and topographic data, etc. Provides specialized functions for calculating seawater properties such as potential temperature in either the UNESCO or TEOS-10 equation of state. Produces graphical displays that conform to the conventions of the Oceanographic literature. This package is discussed extensively by Kelley (2018) "Oceanographic Analysis with R" <doi:10.1007/978-1-4939-8844-0>.

Computes the routing distribution, the expectation of the number of broadcasts, transmissions and receptions considering an Opportunistic transport model. It provides theoretical results and also estimated values based on Monte Carlo simulations.

This package provides a general framework for the application of cross-validation schemes to particular functions. By allowing arbitrary lists of results, origami accommodates a range of cross-validation applications. This implementation was first described by Coyle and Hejazi (2018) <doi:10.21105/joss.00512>.

Allows distance based spatial clustering of georeferenced data by implementing the City Clustering Algorithm - CCA. Multiple versions allow clustering for a matrix, raster and single coordinates on a plain (Euclidean distance) or on a sphere (great-circle or orthodromic distance).

This package provides a database management tool built as a shiny application. Connect to various databases to send queries, upload files, preview tables, and more.

This package provides tools to analyze and infer orthology and paralogy relationships between glutamine synthetase proteins in seed plants.

For the problem of indirect treatment comparison with limited subject-level data, this package provides tools for model-based standardisation with several different computation approaches. See Remiroâ Azócar A, Heath A, Baio G (2022) "Parametric Gâ computation for compatible indirect treatment comparisons with limited individual patient data", Res. Synth. Methods, 1â 31. ISSN 1759-2879, <doi:10.1002/jrsm.1565>.

This package provides a lightweight, fully vectorized N-body physics engine built for the R ecosystem. Simulate and visualize complex orbital mechanics, celestial trajectories, and gravitational interactions using tidy data principles. Features multiple numerical integration methods, including the energy-conserving velocity Verlet algorithm (Verlet (1967) <doi:10.1103/PhysRev.159.98>), to ensure highly stable orbital propagation. Gravitational N-body methods follow Aarseth (2003, ISBN:0-521-43272-3).

Estimate the positron emission tomography (PET) neuroreceptor occupancies from the total volumes of distribution of a set of regions of interest. Fitting methods include the simple reference region', ordinary least squares (sometimes known as occupancy plot), and restricted maximum likelihood estimation'.

Transactions occurring for a UK-based and registered, non-store online retail between 01/12/2010 and 09/12/2011 (Chen et. al., 2012, <doi:10.1145/1835804.1835882>). This dataset is included in this package with the donor's permission, Dr. Daqing Chen.

Extract results into R from the Observational Health Data Sciences and Informatics result database (see <https://ohdsi.github.io/Strategus/results-schema/index.html>) and generate reports/presentations via quarto that summarize results in HTML format. Learn more about OhdsiReportGenerator at <https://ohdsi.github.io/OhdsiReportGenerator/>.

This package provides a comprehensive set of indexes and tests for social segregation analysis, as described in Tivadar (2019) - OasisR': An R Package to Bring Some Order to the World of Segregation Measurement <doi:10.18637/jss.v089.i07>. The package is the most complete existing tool and it clarifies many ambiguities and errors regarding the definition of segregation indices. Additionally, OasisR introduces several resampling methods that enable testing their statistical significance (randomization tests, bootstrapping, and jackknife methods).

It is a computer tool to estimate the item-sum score's reliability (composite reliability, CR) in multidimensional scales with overlapping items. An item that measures more than one domain construct is called an overlapping item. The estimation is based on factor models allowing unlimited cross-factor loadings such as exploratory structural equation modeling (ESEM) and Bayesian structural equation modeling (BSEM). The factor models include correlated-factor models and bi-factor models. Specifically for bi-factor models, a type of hierarchical factor model, the package estimates the CR hierarchical subscale/hierarchy and CR subscale/scale total. The CR estimator Omega-generic was proposed by Mai, Srivastava, and Krull (2021) <https://whova.com/embedded/subsession/enars_202103/1450751/1452993/>. The current version can only handle continuous data. Yujiao Mai contributes to the algorithms, R programming, and application example. Deo Kumar Srivastava contributes to the algorithms and the application example. Kevin R. Krull contributes to the application example. The package OmegaG was sponsored by American Lebanese Syrian Associated Charities (ALSAC). However, the contents of OmegaG do not necessarily represent the policy of the ALSAC.

This package provides a tool for interactive exploration of the results from omics experiments to facilitate novel discoveries from high-throughput biology. The software includes R functions for the bioinformatician to deposit study metadata and the outputs from statistical analyses (e.g. differential expression, enrichment). These results are then exported to an interactive JavaScript dashboard that can be interrogated on the user's local machine or deployed online to be explored by collaborators. The dashboard includes sortable tables, interactive plots including network visualization, and fine-grained filtering based on statistical significance.

This package provides a suite of functions for the design of case-control and two-phase studies, and the analysis of data that arise from them. Functions in this packages provides Monte Carlo based evaluation of operating characteristics such as powers for estimators of the components of a logistic regression model. For additional detail see: Haneuse S, Saegusa T and Lumley T (2011)<doi:10.18637/jss.v043.i11>.

This package provides functions to download and tidy statistical data published by the Office for National Statistics <https://www.ons.gov.uk>. Covers GDP, inflation (CPI, CPIH, RPI), unemployment, employment, wages, trade, retail sales, house prices, productivity, population, and public sector finances. Most series are fetched from the ONS website using its CSV time series endpoint. House price data is sourced from HM Land Registry <https://www.gov.uk/government/organisations/land-registry>. Data is cached locally between sessions.