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Derives group sequential clinical trial designs and describes their properties. Particular focus on time-to-event, binary, and continuous outcomes. Largely based on methods described in Jennison, Christopher and Turnbull, Bruce W., 2000, "Group Sequential Methods with Applications to Clinical Trials" ISBN: 0-8493-0316-8.
Gaussian processes ('GPs') have been widely used to model spatial data, spatio'-temporal data, and computer experiments in diverse areas of statistics including spatial statistics, spatio'-temporal statistics, uncertainty quantification, and machine learning. This package creates basic tools for fitting and prediction based on GPs with spatial data, spatio'-temporal data, and computer experiments. Key characteristics for this GP tool include: (1) the comprehensive implementation of various covariance functions including the Matérn family and the Confluent Hypergeometric family with isotropic form, tensor form, and automatic relevance determination form, where the isotropic form is widely used in spatial statistics, the tensor form is widely used in design and analysis of computer experiments and uncertainty quantification, and the automatic relevance determination form is widely used in machine learning; (2) implementations via Markov chain Monte Carlo ('MCMC') algorithms and optimization algorithms for GP models with all the implemented covariance functions. The methods for fitting and prediction are mainly implemented in a Bayesian framework; (3) model evaluation via Fisher information and predictive metrics such as predictive scores; (4) built-in functionality for simulating GPs with all the implemented covariance functions; (5) unified implementation to allow easy specification of various GPs'.
This package implements general unilateral loading estimator for two-layer latent factor models with smooth, element-wise factor transformations. We provide data simulation, loading estimation,finite-sample error bounds, and diagnostic tools for zero-mean and sub-Gaussian assumptions. A unified interface is given for evaluating estimation accuracy and cosine similarity. The philosophy of the package is described in Guo G. (2026) <doi:10.1016/j.apm.2025.116280>.
Fits a multivariate linear mixed effects model that uses a polygenic term, after Zhou & Stephens (2014) (<https://www.nature.com/articles/nmeth.2848>). Of particular interest is the estimation of variance components with restricted maximum likelihood (REML) methods. Genome-wide efficient mixed-model association (GEMMA), as implemented in the package gemma2', uses an expectation-maximization algorithm for variance components inference for use in quantitative trait locus studies.
This package provides a set of high efficient functions to decode identifiers of National Football League players.
This package purposes to deal with public survey data of Japanese government via their Application Programming Interface (http://statdb.nstac.go.jp/).
This package provides a collection of methods to determine growth rates from experimental data, in particular from batch experiments and plate reader trials.
Fast scalable Gaussian process approximations, particularly well suited to spatial (aerial, remote-sensed) and environmental data, described in more detail in Katzfuss and Guinness (2017) <doi:10.48550/arXiv.1708.06302>. Package also contains a fast implementation of the incomplete Cholesky decomposition (IC0), based on Schaefer et al. (2019) <doi:10.48550/arXiv.1706.02205> and MaxMin ordering proposed in Guinness (2018) <doi:10.48550/arXiv.1609.05372>.
Plot glycans following the Symbol Nomenclature for Glycans (SNFG) using ggplot2'. SNFG provides a standardized visual representation of glycan structures.
This package provides tools for applying the Bayesian Gower agreement methodology (presented in the package vignette) to nominal or ordinal data. The framework can accommodate any number of units, any number of coders, and missingness; and can handle both one-way and two-way random study designs. Influential units and/or coders can be identified easily using leave-one-out statistics.
This package provides two functions that generate source code implementing the predict function of fitted glm objects. In this version, code can be generated for either C or Java'. The idea is to provide a tool for the easy and fast deployment of glm predictive models into production. The source code generated by this package implements two function/methods. One of such functions implements the equivalent to predict(type="response"), while the second implements predict(type="link"). Source code is written to disk as a .c or .java file in the specified path. In the case of c, an .h file is also generated.
This package provides functions to analyze data exported from Google Takeout'. The package supports unzipping archives and extracting user review data from Google Business Profile exports into tidy data frames for further analysis.
This package provides a collection of tools and data for analyzing the Gause microcosm experiments, and for fitting Lotka-Volterra models to time series data. Includes methods for fitting single-species logistic growth, and multi-species interaction models, e.g. of competition, predator/prey relationships, or mutualism. See documentation for individual functions for examples. In general, see the lv_optim() function for examples of how to fit parameter values in multi-species systems. Note that the general methods applied here, as well as the form of the differential equations that we use, are described in detail in the Quantitative Ecology textbook by Lehman et al., available at <http://hdl.handle.net/11299/204551>, and in Lina K. Mühlbauer, Maximilienne Schulze, W. Stanley Harpole, and Adam T. Clark. gauseR': Simple methods for fitting Lotka-Volterra models describing Gause's Struggle for Existence in the journal Ecology and Evolution.
Genotyping of triploid individuals from luminescence data (marker probeset A and B). Works also for diploids. Two main functions: Run_Clustering() that regroups individuals with a same genotype based on proximity and Run_Genotyping() that assigns a genotype to each cluster. For Shiny interface use: launch_GenoShiny().
This package provides a collection of datasets for the upcoming book "Graficas versatiles con ggplot: Analisis visuales de datos", by Raymond L. Tremblay and Julian Hernandez-Serano.
Reads data collected from wearable acceleratometers as used in sleep and physical activity research. Currently supports file formats: binary data from GENEActiv <https://activinsights.com/>, .bin-format from GENEA devices (not for sale), and .cwa-format from Axivity <https://axivity.com>. Further, it has functions for reading text files with epoch level aggregates from Actical', Fitbit', Actiwatch', ActiGraph', and PhilipsHealthBand'. Primarily designed to complement R package GGIR <https://CRAN.R-project.org/package=GGIR>.
Simplify your R data analysis and data visualization workflow by turning your data frame into an interactive Tableau'-like interface, leveraging the graphic-walker JavaScript library and the htmlwidgets package.
This package provides a function that reads in the GEO code of a gene expression dataset, retrieves its data from GEO, (optionally) retrieves the gene symbols of the dataset, and returns a simple dataframe table containing all the data. Platforms available: GPL11532, GPL23126, GPL6244, GPL8300, GPL80, GPL96, GPL570, GPL571, GPL20115, GPL1293, GPL6102, GPL6104, GPL6883, GPL6884, GPL13497, GPL14550, GPL17077, GPL6480. GEO: Gene Expression Omnibus. ID: identifier code. The GEO datasets are downloaded from the URL <https://ftp.ncbi.nlm.nih.gov/geo/series/>. More information can be found in the following manuscript: Davide Chicco, "geneExpressionFromGEO: an R package to facilitate data reading from Gene Expression Omnibus (GEO)". Microarray Data Analysis, Methods in Molecular Biology, volume 2401, chapter 12, pages 187-194, Springer Protocols, 2021, <doi:10.1007/978-1-0716-1839-4_12>.
Calculates grey level co-occurrence matrix (GLCM) based texture measures (Hall-Beyer (2017) <https://prism.ucalgary.ca/bitstream/handle/1880/51900/texture%20tutorial%20v%203_0%20180206.pdf>; Haralick et al. (1973) <doi:10.1109/TSMC.1973.4309314>) of raster layers using a sliding rectangular window. It also includes functions to quantize a raster into grey levels as well as tabulate a glcm and calculate glcm texture metrics for a matrix.
Analyze the default risk of credit portfolios. Commonly known models, like CreditRisk+ or the CreditMetrics model are implemented in their very basic settings. The portfolio loss distribution can be achieved either by simulation or analytically in case of the classic CreditRisk+ model. Models are only implemented to respect losses caused by defaults, i.e. migration risk is not included. The package structure is kept flexible especially with respect to distributional assumptions in order to quantify the sensitivity of risk figures with respect to several assumptions. Therefore the package can be used to determine the credit risk of a given portfolio as well as to quantify model sensitivities.
Make efficient Rust implementations of graph adjustment identification distances available in R. These distances (based on ancestor, optimal, and parent adjustment) count how often the respective adjustment identification strategy leads to causal inferences that are incorrect relative to a ground-truth graph when applied to a candidate graph instead. See also Henckel, Würtzen, Weichwald (2024) <doi:10.48550/arXiv.2402.08616>.
Estimates statistically significant marker combination values within which one immunologically distinctive group (i.e., disease case) is more associated than another group (i.e., healthy control), successively, using various combinations (i.e., "gates") of markers to examine features of cells that may be different between groups. For a two-group comparison, the gateR package uses the spatial relative risk function estimated using the sparr package. Details about the sparr package methods can be found in the tutorial: Davies et al. (2018) <doi:10.1002/sim.7577>. Details about kernel density estimation can be found in J. F. Bithell (1990) <doi:10.1002/sim.4780090616>. More information about relative risk functions using kernel density estimation can be found in J. F. Bithell (1991) <doi:10.1002/sim.4780101112>.
Simulation and analysis of graded response data with different types of estimators. Also, an interactive shiny application is provided with graphics for characteristic and information curves. Samejima (2018) <doi:10.1007/978-1-4757-2691-6_5>.
We define generalized multipartite networks as the joint observation of several networks implying some common pre-specified groups of individuals. The aim is to fit an adapted version of the popular stochastic block model to multipartite networks, as described in Bar-hen, Barbillon and Donnet (2020) <arXiv:1807.10138>.