This package provides classes and helper functions for loading, extracting, converting, manipulating, plotting and aggregating epidemiological parameters for infectious diseases. Epidemiological parameters extracted from the literature are loaded from the epiparameterDB R package.

Automatic generation of quizzes or individual questions for learnr tutorials based on R/exams exercises.

Estimates coefficients of extended LASSO penalized linear regression and generalized linear models. Currently lasso and elastic net penalized linear regression and generalized linear models are considered. This package currently utilizes an accurate approximation of L1 penalty and then a modified Jacobi algorithm to estimate the coefficients. There is provision for plotting of the solutions and predictions of coefficients at given values of lambda. This package also contains functions for cross validation to select a suitable lambda value given the data. Also provides a function for estimation in fused lasso penalized linear regression. For more details, see Mandal, B. N.(2014). Computational methods for L1 penalized GLM model fitting, unpublished report submitted to Macquarie University, NSW, Australia.

Set of wrappers for the ncdf4 package to simplify and extend its reading/writing capabilities into/from multidimensional R arrays.

Computes the Extended Chen-Poisson (ecp) distribution, survival, density, hazard, cumulative hazard and quantile functions. It also allows to generate a pseudo-random sample from this distribution. The corresponding graphics are available. Functions to obtain measures of skewness and kurtosis, k-th raw moments, conditional k-th moments and mean residual life function were added. For details about ecp distribution, see Sousa-Ferreira, I., Abreu, A.M. & Rocha, C. (2023). <doi:10.57805/revstat.v21i2.405>.

This package provides a framework that provides the methods for quantifying entropy-based local indicator of spatial association (ELSA) that can be used for both continuous and categorical data. In addition, this package offers other methods to measure local indicators of spatial associations (LISA). Furthermore, global spatial structure can be measured using a variogram-like diagram, called entrogram. For more information, please check that paper: Naimi, B., Hamm, N. A., Groen, T. A., Skidmore, A. K., Toxopeus, A. G., & Alibakhshi, S. (2019) <doi:10.1016/j.spasta.2018.10.001>.

Implementations of the expected shortfall backtests of Bayer and Dimitriadis (2020) <doi:10.1093/jjfinec/nbaa013> as well as other well known backtests from the literature. Can be used to assess the correctness of forecasts of the expected shortfall risk measure which is e.g. used in the banking and finance industry for quantifying the market risk of investments. A special feature of the backtests of Bayer and Dimitriadis (2020) <doi:10.1093/jjfinec/nbaa013> is that they only require forecasts of the expected shortfall, which is in striking contrast to all other existing backtests, making them particularly attractive for practitioners.

Analyzing censored variables usually requires the use of optimization algorithms. This package provides an alternative algebraic approach to the task of determining the expected value of a random censored variable with a known censoring point. Likewise this approach allows for the determination of the censoring point if the expected value is known. These results are derived under the assumption that the variable follows an Epanechnikov kernel distribution with known mean and range prior to censoring. Statistical functions related to the uncensored Epanechnikov distribution are also provided by this package.

Presents a statistical method that uses a recursive algorithm for signal extraction. The method handles a non-parametric estimation for the correlation of the errors. See "Krivobokova", "Serra", "Rosales" and "Klockmann" (2021) <arXiv:1812.06948> for details.

This package provides a comprehensive toolkit for discovering differential and difference equations from empirical time series data using symbolic regression. The package implements a complete workflow from data preprocessing (including Total Variation Regularized differentiation for noisy economic data), visual exploration of dynamical structure, and symbolic equation discovery via genetic algorithms. It leverages a high-performance Julia backend ('SymbolicRegression.jl') to provide industrial-grade robustness, physics-informed constraints, and rigorous out-of-sample validation. Designed for economists, physicists, and researchers studying dynamical systems from observational data.

Evolutionary game theory applies game theory to evolving populations in biology, see e.g. one of the books by Weibull (1994, ISBN:978-0262731218) or by Sandholm (2010, ISBN:978-0262195874) for more details. A comprehensive set of tools to illustrate the core concepts of evolutionary game theory, such as evolutionary stability or various evolutionary dynamics, for teaching and academic research is provided.

The top-performing ensemble-based Penalized Cox Regression (ePCR) framework developed during the DREAM 9.5 mCRPC Prostate Cancer Challenge <https://www.synapse.org/ProstateCancerChallenge> presented in Guinney J, Wang T, Laajala TD, et al. (2017) <doi:10.1016/S1470-2045(16)30560-5> is provided here-in, together with the corresponding follow-up work. While initially aimed at modeling the most advanced stage of prostate cancer, metastatic Castration-Resistant Prostate Cancer (mCRPC), the modeling framework has subsequently been extended to cover also the non-metastatic form of advanced prostate cancer (CRPC). Readily fitted ensemble-based model S4-objects are provided, and a simulated example dataset based on a real-life cohort is provided from the Turku University Hospital, to illustrate the use of the package. Functionality of the ePCR methodology relies on constructing ensembles of strata in patient cohorts and averaging over them, with each ensemble member consisting of a highly optimized penalized/regularized Cox regression model. Various cross-validation and other modeling schema are provided for constructing novel model objects.

This package provides tools for accessing and analyzing eBird Status and Trends Data Products (<https://science.ebird.org/en/status-and-trends>). eBird (<https://ebird.org/home>) is a global database of bird observations collected by member of the public. eBird Status and Trends uses these data to model global bird distributions, abundances, and population trends at a high spatial and temporal resolution.

The R4EPIs project <https://r4epi.github.io/sitrep/> seeks to provide a set of standardized tools for analysis of outbreak and survey data in humanitarian aid settings. This package currently provides standardized data dictionaries from Medecins Sans Frontieres Operational Centre Amsterdam for outbreak scenarios (Acute Jaundice Syndrome, Cholera, Diphtheria, Measles, Meningitis) and surveys (Retrospective mortality and access to care, Malnutrition, Vaccination coverage and Event Based Surveillance) - as described in the following <https://scienceportal.msf.org/assets/standardised-mortality-surveys?utm_source=chatgpt.com>. In addition, a data generator from these dictionaries is provided. It is also possible to read in any Open Data Kit format data dictionary.

Estimation of production functions by the Olley-Pakes, Levinsohn-Petrin and Wooldridge methodologies. The package aims to reproduce the results obtained with the Stata's user written opreg <http://www.stata-journal.com/article.html?article=st0145> and levpet <http://www.stata-journal.com/article.html?article=st0060> commands. The first was originally proposed by Olley, G.S. and Pakes, A. (1996) <doi:10.2307/2171831>. The second by Levinsohn, J. and Petrin, A. (2003) <doi:10.1111/1467-937X.00246>. And the third by Wooldridge (2009) <doi:10.1016/j.econlet.2009.04.026>.

Computes various effect sizes of the difference, their variance, and confidence interval. This package treats Cohen's d, Hedges d, biased/unbiased c (an effect size between a mean and a constant) and e (an effect size between means without assuming the variance equality).

Mathematical models of infectious diseases in humans and animals. Both, deterministic and stochastic models can be simulated and plotted.

Wrapper for the ggplot2 package that creates a variety of common charts (e.g. bar, line, area, ROC, waterfall, pie) while aiming to reduce typing.

Estimation of fully and partially observed Exponential-Family Random Network Models (ERNM). Exponential-family Random Graph Models (ERGM) and Gibbs Fields are special cases of ERNMs and can also be estimated with the package. Please cite Fellows and Handcock (2012), "Exponential-family Random Network Models" available at <doi:10.48550/arXiv.1208.0121>.

Automates feature engineering using evolutionary algorithms inspired by genetic programming. Starting from raw input features, the package evolves candidate transformation recipes through selection, crossover, and mutation, evaluating fitness via cross-validation or train/validation splits with gradient-boosted tree models ('LightGBM or XGBoost'). Built-in transformers include arithmetic, logarithmic, and power operations, interaction terms, target encoding, quantile and log-based binning, principal component analysis, truncated singular value decomposition, Uniform Manifold Approximation and Projection (UMAP) dimensionality reduction, and minimum spanning tree (MST) graph-based clustering. The evolutionary search yields an optimised feature recipe that can be applied to new data for prediction. Methods are described in McInnes et al. (2018) <doi:10.21105/joss.00861>, Ke et al. (2017) <doi:10.48550/arXiv.1711.08789>, Chen and Guestrin (2016) <doi:10.1145/2939672.2939785>, Gagolewski (2021) <doi:10.1016/j.softx.2021.100722>, Gagolewski (2026) <doi:10.32614/CRAN.package.lumbermark>, and Gagolewski (2026) <doi:10.32614/CRAN.package.deadwood>.

This package provides tools to analyse human and mosquito behavioral interactions and to compute exposure to mosquito bites estimates. Using behavioral data for human individuals and biting patterns for mosquitoes, you will be able to compute hourly exposure for bed net users and non-users, and summarize (e.g. proportion indoors and outdoors, proportion per time periods, and proportion prevented by bed nets) or visualize these dynamics across a 24-hour cycle.

This new extreme conformal prediction framework provides informative prediction intervals at the high-confidence levels for which classical conformal methods fail. In applications with potentially high-impact events, a very high level of confidence is often required for predictions. If that level is too large relative to the amount of data used for calibration, classical conformal methods provide infinitely wide, thus, uninformative prediction intervals. Our extreme conformal procedure bridges extreme value statistics and conformal prediction to provide reliable and informative prediction intervals with high-confidence coverage, which can be constructed using any black-box extreme quantile regression method. A weighted version of the approach can account for nonstationary data. The methodology was introduced in Pasche, Lam, and Engelke (2026) <doi:10.1007/s10687-026-00536-9>.

Conduct one- and two-sample goodness-of-fit tests for univariate data. In the one-sample case, normal, uniform, exponential, Bernoulli, binomial, geometric, beta, Poisson, lognormal, Laplace, asymmetric Laplace, inverse Gaussian, half-normal, chi-squared, gamma, F, Weibull, Cauchy, and Pareto distributions are supported. egof.test() can also test goodness-of-fit to any distribution with a continuous distribution function. A subset of the available distributions can be tested for the composite goodness-of-fit hypothesis, that is, one can test for distribution fit with unknown parameters. P-values are calculated via parametric bootstrap.

An interface to the Python InterpretML framework for fitting explainable boosting machines (EBMs); see Nori et al. (2019) <doi:10.48550/arXiv.1909.09223> for details. EBMs are a modern type of generalized additive model that use tree-based, cyclic gradient boosting with automatic interaction detection. They are often as accurate as state-of-the-art blackbox models while remaining completely interpretable.