This package provides a single, phenome-wide permutation of large-scale biobank data. When a large number of phenotypes are analyzed in parallel, a single permutation across all phenotypes followed by genetic association analyses of the permuted data enables estimation of false discovery rates (FDRs) across the phenome. These FDR estimates provide a significance criterion for interpreting genetic associations in a biobank context. For the basic permutation of unrelated samples, this package takes a sample-by-variable file with ID, genotypic covariates, phenotypic covariates, and phenotypes as input. For data with related samples, it also takes a file with sample pair-wise identity-by-descent information. The function outputs a permuted sample-by-variable file ready for genome-wide association analysis. See Annis et al. (2021) <doi:10.21203/rs.3.rs-873449/v1> for details.

This package provides a series of checks to identify common issues in Study Data Tabulation Model (SDTM) datasets. These checks are intended to be generalizable, actionable, and meaningful for analysis.

This package provides tools for estimating, interpreting, and visualizing Spatial-X (SLX) regression models. Provides a formula-based interface with first-class support for variable-specific weights matrices, higher-order spatial lags, temporally-lagged spatial variables (TSLS), and tidy effects decomposition (direct, indirect, total). Designed to lower the barrier to SLX modeling for applied researchers who already work with sf and lm'-style formulas. Methods follow Wimpy, Whitten, and Williams (2021) <doi:10.1086/710089>.

This package provides tools which allow regression variables to be placed on similar scales, offering computational benefits as well as easing interpretation of regression output.

This package provides a simple interface to recursively list files from a directory, filter them using a regular expression, read their contents, and extract lines that match a user-defined pattern. The package returns a dataframe containing the matched lines, their line numbers, file paths, and the corresponding matched substrings. Designed for quick code base exploration, log inspection, or any use case involving pattern-based file and line filtering.

This package provides a collection of functions that creates graphs with error bars for data collected from one-way or higher factorial designs.

Spatio-temporal change of support (STCOS) methods are designed for statistical inference on geographic and time domains which differ from those on which the data were observed. In particular, a parsimonious class of STCOS models supporting Gaussian outcomes was introduced by Bradley, Wikle, and Holan <doi:10.1002/sta4.94>. The stcos package contains tools which facilitate use of STCOS models.

An Object-oriented Framework for Geostatistical Modeling in S+ containing functions for variogram estimation, variogram fitting and kriging as well as some plot functions. Written entirely in S, therefore works only for small data sets in acceptable computing time.

This package provides functions and benchmark datasets for the economic appraisal of soil and water conservation (SWC) measures in watershed development projects. Implements benefit-cost ratio (BCR), net present value (NPV), internal rate of return (IRR) via the bisection method of Brent (1973, ISBN:9780130223715), modified BCR, marginal rate of return using the CIMMYT (1988, ISBN:9686127127) method, payback period, soil loss economic valuation via the Universal Soil Loss Equation of Wischmeier and Smith (1978, ISBN:0160016258), groundwater recharge valuation, employment generation ratio, sensitivity analysis, switching value analysis, and Monte Carlo simulation. Six datasets are included: state-wise BCR benchmarks from NABARD (2019) watershed evaluations, USLE erodibility parameters for Indian soil orders from NBSS and LUP, rainfall erosivity for twenty Indian districts from IMD data, SWC unit cost norms from PMKSY-WDC (GoI 2015), and two hypothetical datasets for illustration. Methods follow Gittinger (1982, ISBN:9780801825439) and Squire and van der Tak (1975, ISBN:9780801816697).

This package provides functions to calculate some point estimators and estimate their variance under unequal probability sampling without replacement. Single and two-stage sampling designs are considered. Some approximations for the second-order inclusion probabilities (joint inclusion probabilities) are available (sample and population based). A variety of Jackknife variance estimators are implemented. Almost every function is written in C (compiled) code for faster results. The functions incorporate some performance improvements for faster results with large datasets.

This package provides a collection of functions which (i) assess the quality of variable subsets as surrogates for a full data set, in either an exploratory data analysis or in the context of a multivariate linear model, and (ii) search for subsets which are optimal under various criteria. Theoretical support for the heuristic search methods and exploratory data analysis criteria is in Cadima, Cerdeira, Minhoto (2003, <doi:10.1016/j.csda.2003.11.001>). Theoretical support for the leap and bounds algorithm and the criteria for the general multivariate linear model is in Duarte Silva (2001, <doi:10.1006/jmva.2000.1920>). There is a package vignette "subselect", which includes additional references.

Fits (excess) hazard, relative mortality ratio or marginal intensity models with multidimensional penalized splines allowing for time-dependent effects, non-linear effects and interactions between several continuous covariates. In survival and net survival analysis, in addition to modelling the effect of time (via the baseline hazard), one has often to deal with several continuous covariates and model their functional forms, their time-dependent effects, and their interactions. Model specification becomes therefore a complex problem and penalized regression splines represent an appealing solution to that problem as splines offer the required flexibility while penalization limits overfitting issues. Current implementations of penalized survival models can be slow or unstable and sometimes lack some key features like taking into account expected mortality to provide net survival and excess hazard estimates. In contrast, survPen provides an automated, fast, and stable implementation (thanks to explicit calculation of the derivatives of the likelihood) and offers a unified framework for multidimensional penalized hazard and excess hazard models. Later versions (>2.0.0) include penalized models for relative mortality ratio, and marginal intensity in recurrent event setting. survPen may be of interest to those who 1) analyse any kind of time-to-event data: mortality, disease relapse, machinery breakdown, unemployment, etc 2) wish to describe the associated hazard and to understand which predictors impact its dynamics, 3) wish to model the relative mortality ratio between a cohort and a reference population, 4) wish to describe the marginal intensity for recurrent event data. See Fauvernier et al. (2019a) <doi:10.21105/joss.01434> for an overview of the package and Fauvernier et al. (2019b) <doi:10.1111/rssc.12368> for the method.

Perform analysis of variance when the experimental units are spatially correlated. There are two methods to deal with spatial dependence: Spatial autoregressive models (see Rossoni, D. F., & Lima, R. R. (2019) <doi:10.28951/rbb.v37i2.388>) and geostatistics (see Pontes, J. M., & Oliveira, M. S. D. (2004) <doi:10.1590/S1413-70542004000100018>). For both methods, there are three multicomparison procedure available: Tukey, multivariate T, and Scott-Knott.

We provide a collection of statistical hypothesis testing procedures ranging from classical to modern methods for non-trivial settings such as high-dimensional scenario. For the general treatment of statistical hypothesis testing, see the book by Lehmann and Romano (2005) <doi:10.1007/0-387-27605-X>.

This package provides a collection of functions for reading soil data from U.S. Department of Agriculture Natural Resources Conservation Service (USDA-NRCS) and National Cooperative Soil Survey (NCSS) databases.

This is an evolving and growing collection of tools for the quantification, assessment, and comparison of shape and pattern. This collection provides tools for: (1) the spatial decomposition of planar shapes using ShrinkShape to incrementally shrink shapes to extinction while computing area, perimeter, and number of parts at each iteration of shrinking; the spectra of results are returned in graphic and tabular formats (Remmel 2015) <doi:10.1111/cag.12222>, (2) simulating landscape patterns, (3) provision of tools for estimating composition and configuration parameters from a categorical (binary) landscape map (grid) and then simulates a selected number of statistically similar landscapes. Class-focused pattern metrics are computed for each simulated map to produce empirical distributions against which statistical comparisons can be made. The code permits the analysis of single maps or pairs of maps (Remmel and Fortin 2013) <doi:10.1007/s10980-013-9905-x>, (4) counting the number of each first-order pattern element and converting that information into both frequency and empirical probability vectors (Remmel 2020) <doi:10.3390/e22040420>, and (5) computing the porosity of raster patches <doi:10.3390/su10103413>. NOTE: This is a consolidation of existing packages ('PatternClass', ShapePattern') to begin warehousing all shape and pattern code in a common package. Additional utility tools for handling data are provided and this package will be added to as more tools are created, cleaned-up, and documented. Note that all future developments will appear in this package and that PatternClass will eventually be archived.

This package provides a set of functions and datasets implementation of small area estimation when auxiliary variable is measured with error. These functions provide a empirical best linear unbiased prediction (EBLUP) estimator and mean squared error (MSE) estimator of the EBLUP. These models were developed by Ybarra and Lohr (2008) <doi:10.1093/biomet/asn048>.

The statistical tools in this package do one of four things: 1) Enhance basic statistical functions with more flexible inputs, smarter defaults, and richer, clearer, and ready-to-use output (e.g., t.test2()) 2) Produce publication-ready commonly needed figures with one line of code (e.g., plot_cdf()) 3) Implement novel analytical tools developed by the authors (e.g., twolines()) 4) Deliver niche functions of high value to the authors that are not easily available elsewhere (e.g., clear(), convert_to_sql(), resize_images()).

This package provides tools for analyzing tail dependence in any sample or in particular theoretical models. The package uses only theoretical and non parametric methods, without inference. The primary goals of the package are to provide: (a)symmetric multivariate extreme value models in any dimension; theoretical and empirical indices to order tail dependence; theoretical and empirical graphical methods to visualize tail dependence.

Survival analysis with sparse longitudinal covariates under right censoring scheme. Different hazards models are involved. Please cite the manuscripts corresponding to this package: Sun, Z. et al. (2022) <doi:10.1007/s10985-022-09548-6>, Sun, Z. and Cao, H. (2023) <arXiv:2310.15877> and Sun, D. et al. (2023) <arXiv:2308.15549>.

Forms queries to submit to the Cleveland Federal Reserve Bank web site's financial stress index data site. Provides query functions for both the composite stress index and the components data. By default the download includes daily time series data starting September 25, 1991. The functions return a class of either type easing or cfsi which contain a list of items related to the query and its graphical presentation. The list includes the time series data as an xts object. The package provides four lattice time series plots to render the time series data in a manner similar to the bank's own presentation.

Does prediction in the case of a censored survival outcome, or a regression outcome, using the "supervised principal component" approach. Superpc is especially useful for high-dimensional data when the number of features p dominates the number of samples n (p >> n paradigm), as generated, for instance, by high-throughput technologies.

This package creates ggplot2'-based visualizations of smooth effects from GAM (Generalized Additive Models) fitted with mgcv and spline effects from GLM (Generalized Linear Models). Supports survey-weighted models ('svyglm', svycoxph') from the survey package, interaction terms, and provides hazard ratio plots with histograms for survival analysis. Wood (2017, ISBN:9781498728331) provides comprehensive methodology for generalized additive models.

Statistical models for specific coronavirus disease 2019 use cases at German local health authorities. All models of Statistical modelling for infectious disease management smidm are part of the decision support toolkit in the EsteR project. More information is published in Sonja Jäckle, Rieke Alpers, Lisa Kühne, Jakob Schumacher, Benjamin Geisler, Max Westphal "'EsteR â A Digital Toolkit for COVID-19 Decision Support in Local Health Authorities" (2022) <doi:10.3233/SHTI220799> and Sonja Jäckle, Elias Röger, Volker Dicken, Benjamin Geisler, Jakob Schumacher, Max Westphal "A Statistical Model to Assess Risk for Supporting COVID-19 Quarantine Decisions" (2021) <doi:10.3390/ijerph18179166>.