Classification, regression, and clustering with k nearest neighbors algorithm. Implements several distance and similarity measures, covering continuous and logical features. Outputs ranked neighbors. Most features of this package are directly based on the PMML specification for KNN.

An interactive document on the topic of naive Bayes classification analysis using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://kartikeyab.shinyapps.io/NBShiny/>.

This package provides utility functions, distributions, and fitting methods for Bayesian Spatial Capture-Recapture (SCR) and Open Population Spatial Capture-Recapture (OPSCR) modelling using the nimble package (de Valpine et al. 2017 <doi:10.1080/10618600.2016.1172487 >). Development of the package was motivated primarily by the need for flexible and efficient analysis of large-scale SCR data (Bischof et al. 2020 <doi:10.1073/pnas.2011383117 >). Computational methods and techniques implemented in nimbleSCR include those discussed in Turek et al. 2021 <doi:10.1002/ecs2.3385>; among others. For a recent application of nimbleSCR, see Milleret et al. (2021) <doi:10.1098/rsbl.2021.0128>.

Plot, process, and analyze NPO files produced by Nonpareil <http://enve-omics.ce.gatech.edu/nonpareil/>.

Conducts Bayesian Hypothesis tests of a point null hypothesis against a two-sided alternative using Non-local Alternative Prior (NAP) for one- and two-sample z- and t-tests (Pramanik and Johnson, 2022). Under the alternative, the NAP is assumed on the standardized effects size in one-sample tests and on their differences in two-sample tests. The package considers two types of NAP densities: (1) the normal moment prior, and (2) the composite alternative. In fixed design tests, the functions calculate the Bayes factors and the expected weight of evidence for varied effect size and sample size. The package also provides a sequential testing framework using the Sequential Bayes Factor (SBF) design. The functions calculate the operating characteristics (OC) and the average sample number (ASN), and also conducts sequential tests for a sequentially observed data.

This package provides a nomogram can not be easily applied, because it is difficult to calculate the points or even the survival probability. The package, including a function of nomogramEx(), is to extract the polynomial equations to calculate the points of each variable, and the survival probability corresponding to the total points.

In many binary classification applications, such as disease diagnosis and spam detection, practitioners commonly face the need to limit type I error (i.e., the conditional probability of misclassifying a class 0 observation as class 1) so that it remains below a desired threshold. To address this need, the Neyman-Pearson (NP) classification paradigm is a natural choice; it minimizes type II error (i.e., the conditional probability of misclassifying a class 1 observation as class 0) while enforcing an upper bound, alpha, on the type I error. Although the NP paradigm has a century-long history in hypothesis testing, it has not been well recognized and implemented in classification schemes. Common practices that directly limit the empirical type I error to no more than alpha do not satisfy the type I error control objective because the resulting classifiers are still likely to have type I errors much larger than alpha. As a result, the NP paradigm has not been properly implemented for many classification scenarios in practice. In this work, we develop the first umbrella algorithm that implements the NP paradigm for all scoring-type classification methods, including popular methods such as logistic regression, support vector machines and random forests. Powered by this umbrella algorithm, we propose a novel graphical tool for NP classification methods: NP receiver operating characteristic (NP-ROC) bands, motivated by the popular receiver operating characteristic (ROC) curves. NP-ROC bands will help choose in a data adaptive way and compare different NP classifiers.

This package provides a near drop-in replacement for base::Sys.sleep() that allows more types of input to produce delays in the execution of code and can silence/prevent typical sources of error.

NONMEM has been a tool for running nonlinear mixed effects models since the 80s and is still used today (Bauer 2019 <doi:10.1002/psp4.12404>). This tool allows you to convert NONMEM models to rxode2 (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) and with simple models nlmixr2 syntax (Fidler et al (2019) <doi:10.1002/psp4.12445>). The nlmixr2 syntax requires the residual specification to be included and it is not always translated. If available, the rxode2 model will read in the NONMEM data and compare the simulation for the population model ('PRED') individual model ('IPRED') and residual model ('IWRES') to immediately show how well the translation is performing. This saves the model development time for people who are creating an rxode2 model manually. Additionally, this package reads in all the information to allow simulation with uncertainty (that is the number of observations, the number of subjects, and the covariance matrix) with a rxode2 model. This is complementary to the babelmixr2 package that translates nlmixr2 models to NONMEM and can convert the objects converted from nonmem2rx to a full nlmixr2 fit.

This package implements network analysis and graph theory measures used in neuroscience, cognitive science, and psychology. Methods include various filtering methods and approaches such as threshold, dependency (Kenett, Tumminello, Madi, Gur-Gershgoren, Mantegna, & Ben-Jacob, 2010 <doi:10.1371/journal.pone.0015032>), Information Filtering Networks (Barfuss, Massara, Di Matteo, & Aste, 2016 <doi:10.1103/PhysRevE.94.062306>), and Efficiency-Cost Optimization (Fallani, Latora, & Chavez, 2017 <doi:10.1371/journal.pcbi.1005305>). Brain methods include the recently developed Connectome Predictive Modeling (see references in package). Also implements several network measures including local network characteristics (e.g., centrality), community-level network characteristics (e.g., community centrality), global network characteristics (e.g., clustering coefficient), and various other measures associated with the reliability and reproducibility of network analysis.

This R package provides a calculation of between-cases AUC estimate, corresponding covariance, and variance estimate in the nested data problem. Also, the package has the function to simulate the nested data. The calculated between-cases AUC estimate is used to evaluate the reader's diagnostic performance in clinical tasks with nested data. For more details on the above methods, please refer to the paper by H Du, S Wen, Y Guo, F Jin, BD Gallas (2022) <doi:10.1177/09622802221111539>.

This package provides functions for reading cancer record files which follow a format defined by the North American Association of Central Cancer Registries (NAACCR).

This package provides functions complementary to packages nicheROVER and SIBER allowing the user to extract Bayesian estimates from data objects created by the packages nicheROVER and SIBER'. Please see the following publications for detailed methods on nicheROVER and SIBER Hansen et al. (2015) <doi:10.1890/14-0235.1>, Jackson et al. (2011) <do i:10.1111/j.1365-2656.2011.01806.x>, and Layman et al. (2007) <doi:10.1890/0012-9658(2007)88[42:CSIRPF]2.0.CO;2>, respectfully.

Multiple and generalized nonparametric regression using smoothing spline ANOVA models and generalized additive models, as described in Helwig (2020) <doi:10.4135/9781526421036885885>. Includes support for Gaussian and non-Gaussian responses, smoothers for multiple types of predictors (including random intercepts), interactions between smoothers of mixed types, eight different methods for smoothing parameter selection, and flexible tools for diagnostics, inference, and prediction.

This package provides a set of techniques that can be used to develop, validate, and implement automated classifiers. A powerful tool for transforming raw data into meaningful information, ncodeR (Shaffer, D. W. (2017) Quantitative Ethnography. ISBN: 0578191687) is designed specifically for working with big data: large document collections, logfiles, and other text data.

An estimation procedure for the analysis of nonparametric proportional hazards model (e.g. h(t) = h0(t)exp(b(t)'Z)), providing estimation of b(t) and its pointwise standard errors, and semiparametric proportional hazards model (e.g. h(t) = h0(t)exp(b(t)'Z1 + c*Z2)), providing estimation of b(t), c and their standard errors. More details can be found in Lu Tian et al. (2005) <doi:10.1198/016214504000000845>.

This allows you to generate reporting workflows around nlmixr2 analyses with outputs in Word and PowerPoint. You can specify figures, tables and report structure in a user-definable YAML file. Also you can use the internal functions to access the figures and tables to allow their including in other outputs (e.g. R Markdown).

Piecewise constant hazard functions are used to flexibly model survival distributions with non-proportional hazards and to simulate data from the specified distributions. A function to calculate weighted log-rank tests for the comparison of two hazard functions is included. Also, a function to calculate a test using the maximum of a set of test statistics from weighted log-rank tests (MaxCombo test) is provided. This test utilizes the asymptotic multivariate normal joint distribution of the separate test statistics. The correlation is estimated from the data. These methods are described in Ristl et al. (2021) <doi:10.1002/pst.2062>. Finally, a function is provided for the estimation and inferential statistics of various parameters that quantify the difference between two survival curves. Eligible parameters are differences in survival probabilities, log survival probabilities, complementary log log (cloglog) transformed survival probabilities, quantiles of the survival functions, log transformed quantiles, restricted mean survival times, as well as an average hazard ratio, the Cox model score statistic (logrank statistic), and the Cox-model hazard ratio. Adjustments for multiple testing and simultaneous confidence intervals are calculated using a multivariate normal approximation to the set of selected parameters.

Annotated neuroblastoma copy number profiles, a benchmark data set for change-point detection algorithms, as described by Hocking et al. <doi:10.1186/1471-2105-14-164>.

We solve non linear least squares problems with optional equality and/or inequality constraints. Non linear iterations are globalized with back-tracking method. Linear problems are solved by dense QR decomposition from LAPACK which can limit the size of treated problems. On the other side, we avoid condition number degradation which happens in classical quadratic programming approach. Inequality constraints treatment on each non linear iteration is based on NNLS method (by Lawson and Hanson). We provide an original function lsi_ln for solving linear least squares problem with inequality constraints in least norm sens. Thus if Jacobian of the problem is rank deficient a solution still can be provided. However, truncation errors are probable in this case. Equality constraints are treated by using a basis of Null-space. User defined function calculating residuals must return a list having residual vector (not their squared sum) and Jacobian. If Jacobian is not in the returned list, package numDeriv is used to calculated finite difference version of Jacobian. The NLSIC method was fist published in Sokol et al. (2012) <doi:10.1093/bioinformatics/btr716>.

Models for non-linear time series analysis and causality detection. The main functionalities of this package consist of an implementation of the classical causality test (C.W.J.Granger 1980) <doi:10.1016/0165-1889(80)90069-X>, and a non-linear version of it based on feed-forward neural networks. This package contains also an implementation of the Transfer Entropy <doi:10.1103/PhysRevLett.85.461>, and the continuous Transfer Entropy using an approximation based on the k-nearest neighbors <doi:10.1103/PhysRevE.69.066138>. There are also some other useful tools, like the VARNN (Vector Auto-Regressive Neural Network) prediction model, the Augmented test of stationarity, and the discrete and continuous entropy and mutual information.

This is the R API for the nfer formalism (<http://nfer.io/>). nfer was developed to specify event stream abstractions for spacecraft telemetry such as the Mars Science Laboratory. Users write rules using a syntax that borrows heavily from Allen's Temporal Logic that, when applied to an event stream, construct a hierarchy of temporal intervals with data. The R API supports loading rules from a file or mining them from historical data. Traces of events or pools of intervals are provided as data frames.

Non linear dot plots are diagrams that allow dots of varying size to be constructed, so that columns with a large number of samples are reduced in height. Implementation of algorithm described in: Nils Rodrigues and Daniel Weiskopf, "Nonlinear Dot Plots", IEEE Transactions on Visualization and Computer Graphics, vol. 24, no. 1, pp. 616-625, 2018. <doi:10.1109/TVCG.2017.2744018>.

Given a network (e.g. a food web), estimates several network indices. These include: Ascendency network indices, Direct and indirect dependencies, Effective measures, Environ network indices, General network indices, Pathway analysis, Network uncertainty indices and constraint efficiencies and the trophic level and omnivory indices of food webs.