HTTP Request protocols. Implements the GET, POST and multipart POST request.

Using hybrid data, this package created a vividly colored hybrid heat map. The input is two files which are auto-selected. The first file has three columns, the first two for pairs of species, with the third column for the hybrid experiment code (an integer). The second file is a list of code and their descriptions in two columns. The output is a figure showing the hybrid heat map with a color legend.

Analysing time-series accelerometer data to quantify length and intensity of physical activity using hidden Markov models. It also contains the traditional cut-off point method. Witowski V, Foraita R, Pitsiladis Y, Pigeot I, Wirsik N (2014). <doi:10.1371/journal.pone.0114089>.

We provide extensions to the classical dataset "Example 4: Death by the kick of a horse in the Prussian Army" first used by Ladislaus von Bortkeiwicz in his treatise on the Poisson distribution "Das Gesetz der kleinen Zahlen", <DOI:10.1017/S0370164600019453>. As well as an extended time series for the horse-kick death data, we also provide, in parallel, deaths by falling from a horse and by drowning.

Simulate haplotypes through meioses. Allows specification of population parameters.

Simulate and analyze hierarchical composite endpoints. Includes implementation for the kidney hierarchical composite endpoint as defined in Heerspink HL et al (2023) â Development and validation of a new hierarchical composite end point for clinical trials of kidney disease progressionâ (Journal of the American Society of Nephrology 34 (2): 2025â 2038, <doi:10.1681/ASN.0000000000000243>). Win odds, also called Wilcoxon-Mann-Whitney or success odds, is the main analysis method. Other win statistics (win probability, win ratio, net benefit) are also implemented in the univariate case, provided there is no censoring. The win probability analysis is based on the Brunner-Munzel test and uses the DeLong-DeLong-Clarke-Pearson variance estimator, as described by Brunner and Konietschke (2025) in â An unbiased rank-based estimator of the Mannâ Whitney variance including the case of tiesâ (Statistical Papers 66 (1): 20, <doi:10.1007/s00362-024-01635-0>). Stratification and covariate adjustment are performed based on the methodology presented by Koch GG et al. in â Issues for covariance analysis of dichotomous and ordered categorical data from randomized clinical trials and non-parametric strategies for addressing themâ (Statistics in Medicine 17 (15-16): 1863â 92). For a review, see Gasparyan SB et al (2021) â Adjusted win ratio with stratification: Calculation methods and interpretationâ (Statistical Methods in Medical Research 30 (2): 580â 611, <doi:10.1177/0962280220942558>).

Manipulate data through memory-mapped files, as vectors, matrices or arrays. Basic arithmetic functions are implemented, but currently no matrix arithmetic. Can write and read descriptor files for compatibility with the bigmemory package.

Allows to detect spatial clusters of abnormal values on multivariate or functional data (Frévent et al. (2022) <doi:10.32614/RJ-2022-045>). See also: Frévent et al. (2023) <doi:10.1093/jrsssc/qlad017>, Smida et al. (2022) <doi:10.1016/j.csda.2021.107378>, Frévent et al. (2021) <doi:10.1016/j.spasta.2021.100550>. Cucala et al. (2019) <doi:10.1016/j.spasta.2018.10.002>, Cucala et al. (2017) <doi:10.1016/j.spasta.2017.06.001>, Jung and Cho (2015) <doi:10.1186/s12942-015-0024-6>, Kulldorff et al. (2009) <doi:10.1186/1476-072X-8-58>.

This package provides a suite of routines for the hyperdirichlet distribution and reified Bradley-Terry; supersedes the hyperdirichlet package; uses disordR discipline <doi:10.48550/ARXIV.2210.03856>. To cite in publications please use Hankin 2017 <doi:10.32614/rj-2017-061>, and for Generalized Plackett-Luce likelihoods use Hankin 2024 <doi:10.18637/jss.v109.i08>.

Creating effective colour palettes for figures is challenging. This package generates and plot palettes of optimally distinct colours in perceptually uniform colour space, based on iwanthue <http://tools.medialab.sciences-po.fr/iwanthue/>. This is done through k-means clustering of CIE Lab colour space, according to user-selected constraints on hue, chroma, and lightness.

We provide a toolbox to conduct a Bayesian meta-analysis for estimating the current expansion rate of the Universe, called the Hubble constant H0, via time delay cosmography. The input data are Fermat potential difference and time delay estimates. For a robust inference, we assume a Student's t error for these inputs. Given these inputs, the meta-analysis produces posterior samples of the model parameters including the Hubble constant via Metropolis-Hastings within Gibbs. The package provides an option to implement repelling-attracting Metropolis-Hastings within Gibbs in a case where the parameter space has multiple modes.

Apply an adaptation of the SuperFastHash algorithm to any R object. Hash whole R objects or, for vectors or lists, hash R objects to obtain a set of hash values that is stored in a structure equivalent to the input. See <http://www.azillionmonkeys.com/qed/hash.html> for a description of the hash algorithm.

This package contains functions for hidden Markov models with observations having extra zeros as defined in the following two publications, Wang, T., Zhuang, J., Obara, K. and Tsuruoka, H. (2016) <doi:10.1111/rssc.12194>; Wang, T., Zhuang, J., Buckby, J., Obara, K. and Tsuruoka, H. (2018) <doi:10.1029/2017JB015360>. The observed response variable is either univariate or bivariate Gaussian conditioning on presence of events, and extra zeros mean that the response variable takes on the value zero if nothing is happening. Hence the response is modelled as a mixture distribution of a Bernoulli variable and a continuous variable. That is, if the Bernoulli variable takes on the value 1, then the response variable is Gaussian, and if the Bernoulli variable takes on the value 0, then the response is zero too. This package includes functions for simulation, parameter estimation, goodness-of-fit, the Viterbi algorithm, and plotting the classified 2-D data. Some of the functions in the package are based on those of the R package HiddenMarkov by David Harte. This updated version has included an example dataset and R code examples to show how to transform the data into the objects needed in the main functions. We have also made changes to increase the speed of some of the functions.

The conditional treatment effect for competing risks data in observational studies is estimated. While it is described as a constant difference between the hazard functions given the covariates, we do not assume specific functional forms for the covariates. Rava, D. and Xu, R. (2021) <arXiv:2112.09535>.

This package provides functions for calculating the hazard discrimination summary and its standard errors, as described in Liang and Heagerty (2016) <doi:10.1111/biom.12628>.

This package contains the National Health and Nutrition Examination Survey 24-hour dietary recall data and Healthy Eating Index scoring standards used by the heiscore package.

This package provides a multiple-testing procedure for high-dimensional mediation hypotheses. Mediation analysis is of rising interest in epidemiology and clinical trials. Among existing methods for mediation analyses, the popular joint significance (JS) test yields an overly conservative type I error rate and therefore low power. In the R package HDMT we implement a multiple-testing procedure that accurately controls the family-wise error rate (FWER) and the false discovery rate (FDR) when using JS for testing high-dimensional mediation hypotheses. The core of our procedure is based on estimating the proportions of three component null hypotheses and deriving the corresponding mixture distribution of null p-values. Results of the data examples include better-behaved quantile-quantile plots and improved detection of novel mediation relationships on the role of DNA methylation in genetic regulation of gene expression. With increasing interest in mediation by molecular intermediaries such as gene expression, the proposed method addresses an unmet methodological challenge. Methods used in the package refer to James Y. Dai, Janet L. Stanford & Michael LeBlanc (2020) <doi:10.1080/01621459.2020.1765785>.

Objective: Implement new methods for detecting change points in high-dimensional time series data. These new methods can be applied to non-Gaussian data, account for spatial and temporal dependence, and detect a wide variety of change-point configurations, including changes near the boundary and changes in close proximity. Additionally, this package helps address the â small n, large pâ problem, which occurs in many research contexts. This problem arises when a dataset contains changes that are visually evident but do not rise to the level of statistical significance due to the small number of observations and large number of parameters. The problem is overcome by treating the dimensions as a whole and scaling the test statistics only by its standard deviation, rather than scaling each dimension individually. Due to the computational complexity of the functions, the package runs best on datasets with a relatively large number of attributes but no more than a few hundred observations.

Shiny-App that allows to annotate vectors of texts to predefined categories by hand.

The HistData package provides a collection of small data sets that are interesting and important in the history of statistics and data visualization. The goal of the package is to make these available, both for instructional use and for historical research. Some of these present interesting challenges for graphics or analysis in R.

This package provides utility functions that are simply, frequently used, but may require higher performance that what can be obtained from base R. Incidentally provides support for reverse geocoding', such as matching a point with its nearest neighbour in another array. Used as a complement to package hutils by sacrificing compilation or installation time for higher running speeds. The name is a portmanteau of the author and Rcpp'.

This package provides an example HiC dataset and two examples of HiCociety outputs from a function named hic2community(). The data are intended for demonstration purposes only and kept small enough to be distributed via CRAN.

Identifying labeled compounds in a 13C-tracer experiment in non-targeted fashion is a cumbersome process. This package facilitates such type of analyses by providing high level quality control plots, deconvoluting and evaluating spectra and performing a multitude of tests in an automatic fashion. The main idea is to use changing intensity ratios of ion pairs from peak list generated with xcms as candidates and evaluate those against base peak chromatograms and spectra information within the raw measurement data automatically. The functionality is described in Hoffmann et al. (2018) <doi:10.1021/acs.analchem.8b00356>.

We provide an R tool for computation and nonparametric plug-in estimation of Highest Density Regions (HDRs) and general level sets in the directional setting. Concretely, circular and spherical HDRs can be reconstructed from a data sample following Saavedra-Nieves and Crujeiras (2021) <doi:10.1007/s11634-021-00457-4>. This library also contains two real datasets in the circular and spherical settings. The first one concerns a problem from animal orientation studies and the second one is related to earthquakes occurrences.