This package contains a module to define neural networks from custom components and versions of Autoencoder, BP, LVQ, MAM NN.

This package provides tools for working with nonlinear least squares problems. For the estimation of models reliable and robust tools than nls(), where the the Gauss-Newton method frequently stops with singular gradient messages. This is accomplished by using, where possible, analytic derivatives to compute the matrix of derivatives and a stabilization of the solution of the estimation equations. Tools for approximate or externally supplied derivative matrices are included. Bounds and masks on parameters are handled properly.

Multivariate Normal (i.e. Gaussian) Mixture Models (S3) Classes. Fitting models to data using MLE (maximum likelihood estimation) for multivariate normal mixtures via smart parametrization using the LDL (Cholesky) decomposition, see McLachlan and Peel (2000, ISBN:9780471006268), Celeux and Govaert (1995) <doi:10.1016/0031-3203(94)00125-6>.

Palettes generated from NBA jersey colorways.

Classification, regression, and clustering with k nearest neighbors algorithm. Implements several distance and similarity measures, covering continuous and logical features. Outputs ranked neighbors. Most features of this package are directly based on the PMML specification for KNN.

This package provides a toolbox for calculating continuous norms for psychological tests, where the norms can be age-dependent. The norms are based Generalized Additive Models for Location, Scale, and Shape (GAMLSS) for the test scores in the normative sample. The package includes functions for model selection, reliability estimation, and calculating norms, including confidence intervals. For more details, see Timmerman et al. (2021) <doi:10.1037/met0000348>.

Annotated neuroblastoma copy number profiles, a benchmark data set for change-point detection algorithms, as described by Hocking et al. <doi:10.1186/1471-2105-14-164>.

Conduct a noncompartmental analysis with industrial strength. Some features are 1) Use of CDISC SDTM terms 2) Automatic or manual slope selection 3) Supporting both linear-up linear-down and linear-up log-down method 4) Interval(partial) AUCs with linear or log interpolation method * Reference: Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016. (ISBN:9198299107).

This package provides utility functions and custom probability distribution for Bayesian analyses of radiocarbon dates within the nimble modelling framework. It includes various population growth models, nimbleFunction objects, as well as a suite of functions for prior and posterior predictive checks for demographic inference (Crema and Shoda (2021) <doi:10.1371/journal.pone.0251695>) and other analyses.

Variational Expectation-Maximization algorithm to fit the noisy stochastic block model to an observed dense graph and to perform a node clustering. Moreover, a graph inference procedure to recover the underlying binary graph. This procedure comes with a control of the false discovery rate. The method is described in the article "Powerful graph inference with false discovery rate control" by T. Rebafka, E. Roquain, F. Villers (2020) <arXiv:1907.10176>.

Do algebraic operations on neural networks. We seek here to implement in R, operations on neural networks and their resulting approximations. Our operations derive their descriptions mainly from Rafi S., Padgett, J.L., and Nakarmi, U. (2024), "Towards an Algebraic Framework For Approximating Functions Using Neural Network Polynomials", <doi:10.48550/arXiv.2402.01058>, Grohs P., Hornung, F., Jentzen, A. et al. (2023), "Space-time error estimates for deep neural network approximations for differential equations", <doi:10.1007/s10444-022-09970-2>, Jentzen A., Kuckuck B., von Wurstemberger, P. (2023), "Mathematical Introduction to Deep Learning Methods, Implementations, and Theory" <doi:10.48550/arXiv.2310.20360>. Our implementation is meant mainly as a pedagogical tool, and proof of concept. Faster implementations with deeper vectorizations may be made in future versions.

An array of nonparametric and parametric estimation methods for cognitive diagnostic models, including nonparametric classification of examinee attribute profiles, joint maximum likelihood estimation (JMLE) of examinee attribute profiles and item parameters, and nonparametric refinement of the Q-matrix, as well as conditional maximum likelihood estimation (CMLE) of examinee attribute profiles given item parameters and CMLE of item parameters given examinee attribute profiles. Currently the nonparametric methods in the package support both conjunctive and disjunctive models, and the parametric methods in the package support the DINA model, the DINO model, the NIDA model, the G-NIDA model, and the R-RUM model.

An implementation of the Naive Bayes Classifier (NBC) algorithm used for Verbal Autopsy (VA) built on code from Miasnikof et al (2015) <DOI:10.1186/s12916-015-0521-2>.

Implementation of the NetCutter algorithm described in Müller and Mancuso (2008) <doi:10.1371/journal.pone.0003178>. The package identifies co-occurring terms in a list of containers. For example, it may be used to detect genes that co-occur across genomes.

An R-package for calculating sample size of a survival trial with or without cure fractions.

This shows how NONMEM(R) software works. NONMEM's classical estimation methods like First Order(FO) approximation', First Order Conditional Estimation(FOCE)', and Laplacian approximation are explained.

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the rxode2 package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>). This package is for ggplot2 plotting methods for nlmixr2 objects.

Renders dynamic network data from networkDynamic objects as movies, interactive animations, or other representations of changing relational structures and attributes.

Package including an interactive Shiny application for testing normality visually.

The number of distinct alleles observed in a DNA mixture is informative of the number of contributors to the mixture. The package provides methods for computing the probability distribution of the number of distinct alleles in a mixture for a given set of allele frequencies. The mixture contributors may be related according to a provided pedigree.

Base package for Neuroconductor', which includes many helper functions that interact with objects of class nifti', implemented by package oro.nifti', for reading/writing and also other manipulation functions.

This package provides a graphical display of results from network meta-analysis (NMA). It is suitable for outcomes like odds ratio (OR), risk ratio (RR), risk difference (RD) and standardized mean difference (SMD). It also has an option to visually display and compare the surface under the cumulative ranking (SUCRA) of different treatments.

Calculates phenological cycle and anomalies using a non-parametric approach applied to time series of vegetation indices derived from remote sensing data or field measurements. The package implements basic and high-level functions for manipulating vector data (numerical series) and raster data (satellite derived products). Processing of very large raster files is supported. For more information, please check the following paper: Chávez et al. (2023) <doi:10.3390/rs15010073>.

Setup, run and analyze NetLogo (<https://www.netlogo.org>) model simulations in R'. nlrx experiments use a similar structure as NetLogos Behavior Space experiments. However, nlrx offers more flexibility and additional tools for running and analyzing complex simulation designs and sensitivity analyses. The user defines all information that is needed in an intuitive framework, using class objects. Experiments are submitted from R to NetLogo via XML files that are dynamically written, based on specifications defined by the user. By nesting model calls in future environments, large simulation design with many runs can be executed in parallel. This also enables simulating NetLogo experiments on remote high performance computing machines. In order to use this package, Java and NetLogo (>= 5.3.1) need to be available on the executing system.