This package provides a comprehensive interface for Google Gemini API, enabling users to access and utilize Gemini Large Language Model (LLM) functionalities directly from R. This package facilitates seamless integration with Google Gemini, allowing for advanced language processing, text generation, and other AI-driven capabilities within the R environment. For more information, please visit <https://ai.google.dev/docs/gemini_api_overview>.

This package provides functions for the g-and-k and generalised g-and-h distributions.

Multi-threaded GIF encoder written in Rust: <https://gif.ski/>. Converts images to GIF animations using pngquant's efficient cross-frame palettes and temporal dithering with thousands of colors per frame.

Likelihood ratio tests for genome-wide association and genome-wide linkage analysis under heterogeneity.

This package implements key features of Gephi for network visualization, including ForceAtlas2 (with LinLog mode), network scaling, and network rotations. It also includes easy network visualization tools such as edge and node color assignment for recreating Gephi'-style graphs in R. The package references layout algorithms developed by Jacomy, M., Venturini T., Heymann S., and Bastian M. (2014) <doi:10.1371/journal.pone.0098679> and Noack, A. (2009) <doi:10.48550/arXiv.0807.4052>.

This package provides a novel statistical model to detect the joint genetic and dynamic gene-environment (GxE) interaction with continuous traits in genetic association studies. It uses varying-coefficient models to account for different GxE trajectories, regardless whether the relationship is linear or not. The package includes one function, GxEtest(), to test a single genetic variant (e.g., a single nucleotide polymorphism or SNP), and another function, GxEscreen(), to test for a set of genetic variants. The method involves a likelihood ratio test described in Crainiceanu, C. M., and Ruppert, D. (2004) <doi:10.1111/j.1467-9868.2004.00438.x>.

An implementation of a new Gini covariance and correlation to measure dependence between a categorical and numerical variables. Dang, X., Nguyen, D., Chen, Y. and Zhang, J., (2018) <arXiv:1809.09793>.

Collection of functions to enhance ggplot2 and ggiraph'. Provides functions for exploratory plots. All plot can be a static plot or an interactive plot using ggiraph'.

Create stunning network experiences powered by the G6 graph visualisation engine JavaScript library <https://g6.antv.antgroup.com/en>. In shiny mode, modify your graph directly from the server function to dynamically interact with nodes and edges. Select your favorite layout among 20 choices. 15 behaviors are available such as interactive edge creation, collapse-expand and brush select. 17 plugins designed to improve the user experience such as a mini-map, toolbars and grid lines. Customise the look and feel of your graph with comprehensive options for nodes, edges and more.

R's sf package ships with self-contained GDAL executables, including a bare bones interface to several GDAL'-related utility programs collectively known as the GDAL utilities'. For each of those utilities, this package provides an R wrapper whose formal arguments closely mirror those of the GDAL command line interface. The utilities operate on data stored in files and typically write their output to other files. Therefore, to process data stored in any of R's more common spatial formats (i.e. those supported by the sf and terra packages), first write them to disk, then process them with the package's wrapper functions before reading the outputted results back into R. GDAL function arguments introduced in GDAL version 3.5.2 or earlier are supported.

Integrates with your RMarkdown documents to automatically publish figures to the <https://GoFigr.io> service. Supports both knitr and interactive execution within RStudio'.

Estimation, model selection and other aspects of statistical inference in Graphical Gaussian models with edge and vertex symmetries (Graphical Gaussian models with colours). Documentation about gRc is provided in the paper by Hojsgaard and Lauritzen (2007, <doi:10.18637/jss.v023.i06>) and the paper by Hojsgaard and Lauritzen (2008, <doi:10.1111/j.1467-9868.2008.00666.x>).

This package creates ideal data for all distributions in the generalized linear model framework.

Description: For the risk, progression, and response to treatment of many complex diseases, it has been increasingly recognized that gene-environment interactions play important roles beyond the main genetic and environmental effects. In practical interaction analyses, outliers in response variables and covariates are not uncommon. In addition, missingness in environmental factors is routinely encountered in epidemiological studies. The developed package consists of five robust approaches to address the outliers problems, among which two approaches can also accommodate missingness in environmental factors. Both continuous and right censored responses are considered. The proposed approaches are based on penalization and sparse boosting techniques for identifying important interactions, which are realized using efficient algorithms. Beyond the gene-environment analysis, the developed package can also be adopted to conduct analysis on interactions between other types of low-dimensional and high-dimensional data. (Mengyun Wu et al (2017), <doi:10.1080/00949655.2018.1523411>; Mengyun Wu et al (2017), <doi:10.1002/gepi.22055>; Yaqing Xu et al (2018), <doi:10.1080/00949655.2018.1523411>; Yaqing Xu et al (2019), <doi:10.1016/j.ygeno.2018.07.006>; Mengyun Wu et al (2021), <doi:10.1093/bioinformatics/btab318>).

This package provides functions for efficiently fitting linear models with spatially correlated errors by robust (Kuensch et al. (2011) <doi:10.3929/ethz-a-009900710>) and Gaussian (Harville (1977) <doi:10.1080/01621459.1977.10480998>) (Restricted) Maximum Likelihood and for computing robust and customary point and block external-drift Kriging predictions (Cressie (1993) <doi:10.1002/9781119115151>), along with utility functions for variogram modelling in ad hoc geostatistical analyses, model building, model evaluation by cross-validation, (conditional) simulation of Gaussian processes (Davies and Bryant (2013) <doi:10.18637/jss.v055.i09>), unbiased back-transformation of Kriging predictions of log-transformed data (Cressie (2006) <doi:10.1007/s11004-005-9022-8>).

Procedures for calculating variance components, study variation, percent study variation, and percent tolerance for gauge repeatability and reproducibility study. Methods included are ANOVA and Average / Range methods. Requires balanced study.

Makes the Genepop software available in R. This software implements a mixture of traditional population genetic methods and some more focused developments: it computes exact tests for Hardy-Weinberg equilibrium, for population differentiation and for genotypic disequilibrium among pairs of loci; it computes estimates of F-statistics, null allele frequencies, allele size-based statistics for microsatellites, etc.; and it performs analyses of isolation by distance from pairwise comparisons of individuals or population samples.

This package provides a network-based gene weighting algorithm for pathway enrichment analysis, using either RNA-seq or microarray data. Zhaoyuan Fang, Weidong Tian and Hongbin Ji (2012) <doi:10.1038/cr.2011.149>.

Streamlines exploratory data analysis by providing a turnkey approach to visualising n-dimensional data which graphically reveals correlative or associative relationships between 2 or more features. Represents all dataset features as distinct, vertically aligned bar or tile plots, with plot types auto-selected based on whether variables are categorical or numeric.

This package provides a gradient descent algorithm to find a geodesic relationship between real-valued independent variables and a manifold-valued dependent variable (i.e. geodesic regression). Available manifolds are Euclidean space, the sphere, hyperbolic space, and Kendall's 2-dimensional shape space. Besides the standard least-squares loss, the least absolute deviations, Huber, and Tukey biweight loss functions can also be used to perform robust geodesic regression. Functions to help choose appropriate cutoff parameters to maintain high efficiency for the Huber and Tukey biweight estimators are included, as are functions for generating random tangent vectors from the Riemannian normal distributions on the sphere and hyperbolic space. The n-sphere is a n-dimensional manifold: we represent it as a sphere of radius 1 and center 0 embedded in (n+1)-dimensional space. Using the hyperboloid model of hyperbolic space, n-dimensional hyperbolic space is embedded in (n+1)-dimensional Minkowski space as the upper sheet of a hyperboloid of two sheets. Kendall's 2D shape space with K landmarks is of real dimension 2K-4; preshapes are represented as complex K-vectors with mean 0 and magnitude 1. Details are described in Shin, H.-Y. and Oh, H.-S. (2020) <arXiv:2007.04518>. Also see Fletcher, P. T. (2013) <doi:10.1007/s11263-012-0591-y>.

This package provides a genetic algorithm framework for regression problems requiring discrete optimization over model spaces with unknown or varying dimension, where gradient-based methods and exhaustive enumeration are impractical. Uses a compact chromosome representation for tasks including spline knot placement and best-subset variable selection, with constraint-preserving crossover and mutation, exact uniform initialization under spacing constraints, steady-state replacement, and optional island-model parallelization from Lu, Lund, and Lee (2010, <doi:10.1214/09-AOAS289>). The computation is built on the GA engine of Scrucca (2017, <doi:10.32614/RJ-2017-008>) and changepointGA engine from Li and Lu (2024, <doi:10.48550/arXiv.2410.15571>). In challenging high-dimensional settings, GAReg enables efficient search and delivers near-optimal solutions when alternative algorithms are not well-justified.

This package provides flexible tools for the visualization of genomic data. Supports interactive and static plots tailored for presentations and publications, with customizable features like colors, themes, and annotations to align with specific analytical and presentation goals.

This package provides a statistical hypothesis test for conditional independence. Given residuals from a sufficiently powerful regression, it tests whether the covariance of the residuals is vanishing. It can be applied to both discretely-observed functional data and multivariate data. Details of the method can be found in Anton Rask Lundborg, Rajen D. Shah and Jonas Peters (2022) <doi:10.1111/rssb.12544>.

Implementations of the treatment effect estimators for hybrid (self-selection) experiments, as developed by Brian J. Gaines and James H. Kuklinski, (2011), "Experimental Estimation of Heterogeneous Treatment Effects Related to Self-Selection," American Journal of Political Science 55(3): 724-736.