This package makes available 50 objective functions for benchmarking the performance of global optimization algorithms.

An R interface to weighted nonlinear least-squares optimization with the GNU Scientific Library (GSL), see M. Galassi et al. (2009, ISBN:0954612078). The available trust region methods include the Levenberg-Marquardt algorithm with and without geodesic acceleration, the Steihaug-Toint conjugate gradient algorithm for large systems and several variants of Powell's dogleg algorithm. Multi-start optimization based on quasi-random samples is implemented using a modified version of the algorithm in Hickernell and Yuan (1997, OR Transactions). Robust nonlinear regression can be performed using various robust loss functions, in which case the optimization problem is solved by iterative reweighted least squares (IRLS). Bindings are provided to tune a number of parameters affecting the low-level aspects of the trust region algorithms. The interface mimics R's nls() function and returns model objects inheriting from the same class.

Draw posterior samples to estimate the precision matrix for multivariate Gaussian data. Posterior means of the samples is the graphical horseshoe estimate by Li, Bhadra and Craig(2017) <arXiv:1707.06661>. The function uses matrix decomposition and variable change from the Bayesian graphical lasso by Wang(2012) <doi:10.1214/12-BA729>, and the variable augmentation for sampling under the horseshoe prior by Makalic and Schmidt(2016) <arXiv:1508.03884>. Structure of the graphical horseshoe function was inspired by the Bayesian graphical lasso function using blocked sampling, authored by Wang(2012) <doi:10.1214/12-BA729>.

Writes SAS code to get predicted values from every tree of a gbm.object.

Facilitates efficient visualization of Relative Synonymous Codon Usage patterns across species. Based on analytical outputs from codonW', MEGA', and Phylosuite', it supports multi-species RSCU comparisons and allows users to explore visual analysis of structurally similar datasets.

The Grouphmap was implemented in R, an open-source programming environment, and was released under the provided website. The difference analysis is based on the limma package, which can cover gene and protein expression profiles (Reference: Matthew E Ritchie , Belinda Phipson , Di Wu , Yifang Hu , Charity W Law , Wei Shi , Gordon K Smyth (2015) <doi:10.1093/nar/gkv007>). The GO enrichment analysis is based on the clusterProfiler package and supports three common species: human, mouse, and yeast (Reference: Guangchuang Yu, Li-Gen Wang, Yanyan Han, Qing-Yu He (2012) <doi:10.1089/omi.2011.0118>). The results of batch difference analysis and enrichment analysis are output in separate folders for easy viewing and further visualization of the results during the process. The results returned a heatmap in R and exported to 3 folders named DEG, go, and merge.

This package implements a geographically weighted non-negative principal components analysis, which consists of the fusion of geographically weighted and sparse non-negative principal components analyses <doi:10.17608/k6.auckland.9850826.v1>.

This package contains methods for fitting Generalized Linear Models (GLMs) and Generalized Additive Models (GAMs). Generalized regression models are common methods for handling data for which assuming Gaussian-distributed errors is not appropriate. For instance, if the response of interest is binary, count, or proportion data, one can instead model the expectation of the response based on an appropriate data-generating distribution. This package provides methods for fitting GLMs and GAMs under Beta regression, Poisson regression, Gamma regression, and Binomial regression (currently GLM only) settings. Models are fit using local scoring algorithms described in Hastie and Tibshirani (1990) <doi:10.1214/ss/1177013604>.

This package provides a high performance interface to the Global Biodiversity Information Facility, GBIF'. In contrast to rgbif', which can access small subsets of GBIF data through web-based queries to a central server, gbifdb provides enhanced performance for R users performing large-scale analyses on servers and cloud computing providers, providing full support for arbitrary SQL or dplyr operations on the complete GBIF data tables (now over 1 billion records, and over a terabyte in size). gbifdb accesses a copy of the GBIF data in parquet format, which is already readily available in commercial computing clouds such as the Amazon Open Data portal and the Microsoft Planetary Computer, or can be accessed directly without downloading, or downloaded to any server with suitable bandwidth and storage space. The high-performance techniques for local and remote access are described in <https://duckdb.org/why_duckdb> and <https://arrow.apache.org/docs/r/articles/fs.html> respectively.

Turn arbitrary functions into binary operators.

Analytics to read in and segment raw GENEActiv accelerometer data into epochs and events. For more details on the GENEActiv device, see <https://activinsights.com/resources/geneactiv-support-1-2/>.

This package provides functions for simulating and estimating parameters of various growth models, including Logistic, Exponential, Theta-logistic, Von-Bertalanffy, and Gompertz models. The package supports both simulated and real data analysis, including parameter estimation, visualization, and calculation of global and local estimates. The methods are based on research described by Md Aktar Ul Karim and Amiya Ranjan Bhowmick (2022) in (<https://www.researchsquare.com/article/rs-2363586/v1>). An interactive web application is also available at [GPEMR Web App](<https://gpem-r.shinyapps.io/GPEM-R/>).

Computes the probability density, survival function, the hazard rate functions and generates random samples from the GTDL distribution given by Mackenzie, G. (1996) <doi:10.2307/2348408>. The likelihood estimates, the randomized quantile (Louzada, F., et al. (2020) <doi:10.1109/ACCESS.2020.3040525>) residuals and the normally transformed randomized survival probability (Li,L., et al. (2021) <doi:10.1002/sim.8852>) residuals are obtained for the GTDL model.

Estimation and inference using the Generalized Maximum Entropy (GME) and Generalized Cross Entropy (GCE) framework, a flexible method for solving ill-posed inverse problems and parameter estimation under uncertainty (Golan, Judge, and Miller (1996, ISBN:978-0471145925) "Maximum Entropy Econometrics: Robust Estimation with Limited Data"). The package includes routines for generalized cross entropy estimation of linear models including the implementation of a GME-GCE two steps approach. Diagnostic tools, and options to incorporate prior information through support and prior distributions are available (Macedo, Cabral, Afreixo, Macedo and Angelelli (2025) <doi:10.1007/978-3-031-97589-9_21>). In particular, support spaces can be defined by the user or be internally computed based on the ridge trace or on the distribution of standardized regression coefficients. Different optimization methods for the objective function can be used. An adaptation of the normalized entropy aggregation (Macedo and Costa (2019) <doi:10.1007/978-3-030-26036-1_2> "Normalized entropy aggregation for inhomogeneous large-scale data") and a two-stage maximum entropy approach for time series regression (Macedo (2022) <doi:10.1080/03610918.2022.2057540>) are also available. Suitable for applications in econometrics, health, signal processing, and other fields requiring robust estimation under data constraints.

Providing access to the API for Gas Infrastructure Europe's natural gas transparency platforms <https://agsi.gie.eu/> and <https://alsi.gie.eu/>. Lets the user easily download metadata on companies and gas storage units covered by the API as well as the respective data on regional, country, company or facility level.

Providing publication-ready graphs for Multiple sequence alignment. Moreover, it provides a unique solution for visualizing the multiple sequence alignment without the need to do the alignment in each run which is a big limitation in other available packages.

Execute Latent Class Analysis (LCA) and Latent Class Regression (LCR) by using Generalized Structured Component Analysis (GSCA). This is explained in Ryoo, Park, and Kim (2019) <doi:10.1007/s41237-019-00084-6>. It estimates the parameters of latent class prevalence and item response probability in LCA with a single line comment. It also provides graphs of item response probabilities. In addition, the package enables to estimate the relationship between the prevalence and covariates.

Simulate and analyze multistate models with general hazard functions. gems provides functionality for the preparation of hazard functions and parameters, simulation from a general multistate model and predicting future events. The multistate model is not required to be a Markov model and may take the history of previous events into account. In the basic version, it allows to simulate from transition-specific hazard function, whose parameters are multivariable normally distributed.

This package implements the gene-based segregation test(GESE) and the weighted GESE test for identifying genes with causal variants of large effects for family-based sequencing data. The methods are described in Qiao, D. Lange, C., Laird, N.M., Won, S., Hersh, C.P., et al. (2017). <DOI:10.1002/gepi.22037>. Gene-based segregation method for identifying rare variants for family-based sequencing studies. Genet Epidemiol 41(4):309-319. More details can be found at <http://scholar.harvard.edu/dqiao/gese>.

This is a dataset package for GANPA, which implements a network-based gene weighting approach to pathway analysis. This package includes data useful for GANPA, such as a functional association network, pathways, an expression dataset and multi-subunit proteins.

Generalized Turnbull's estimator proposed by Dehghan and Duchesne (2011).

Discrete scales for the colorblind-friendly Okabe-Ito palette, including color', fill', and edge_colour'. ggokabeito provides ggplot2 and ggraph scales to easily use the Okabe-Ito palette in your data visualizations.

This package implements a new multiple imputation method that draws imputations from a latent joint multivariate normal model which underpins generally structured data. This model is constructed using a sequence of flexible conditional linear models that enables the resulting procedure to be efficiently implemented on high dimensional datasets in practice. See Robbins (2021) <arXiv:2008.02243>.

Utilities to cost and evaluate Australian tax policy, including fast projections of personal income tax collections, high-performance tax and transfer calculators, and an interface to common indices from the Australian Bureau of Statistics. Written to support Grattan Institute's Australian Perspectives program, and related projects. Access to the Australian Taxation Office's sample files of personal income tax returns is assumed.