This package provides a blind spike program provides samples to a laboratory in order to perform quality control (QC) checks. The samples provided are of a known quantity to the tester. The laboratory is typically uninformed of that the sample provided is a QC sample.

Multivariate tool for analyzing genome-wide association study results in the form of univariate summary statistics. The goal of bmass is to comprehensively test all possible multivariate models given the phenotypes and datasets provided. Multivariate models are determined by assigning each phenotype to being either Unassociated (U), Directly associated (D) or Indirectly associated (I) with the genetic variant of interest. Test results for each model are presented in the form of Bayes factors, thereby allowing direct comparisons between models. The underlying framework implemented here is based on the modeling developed in "A Unified Framework for Association Analysis with Multiple Related Phenotypes", M. Stephens (2013) <doi:10.1371/journal.pone.0065245>.

Reads several formats of 13C data (IRIS/Wagner, BreathID) and CSV. Creates artificial sample data for testing. Fits Maes/Ghoos, Bluck-Coward self-correcting formula using nls', nlme'. Methods to fit breath test curves with Bayesian Stan methods are refactored to package breathteststan'. For a Shiny GUI, see package dmenne/breathtestshiny on github.

Simultaneously clusters the Periodontal diseases (PD) patients and their tooth sites after taking the patient- and site-level covariates into consideration. BAREB uses the determinantal point process (DPP) prior to induce diversity among different biclusters to facilitate parsimony and interpretability. Essentially, BAREB is a cluster-wise linear model based on Yuliang (2020) <doi:10.1002/sim.8536>.

An implementation of sensitivity and robustness methods in Bayesian networks in R. It includes methods to perform parameter variations via a variety of co-variation schemes, to compute sensitivity functions and to quantify the dissimilarity of two Bayesian networks via distances and divergences. It further includes diagnostic methods to assess the goodness of fit of a Bayesian networks to data, including global, node and parent-child monitors. Reference: M. Leonelli, R. Ramanathan, R.L. Wilkerson (2022) <doi:10.1016/j.knosys.2023.110882>.

This package implements unit root tests for bounded time series following Cavaliere and Xu (2014) <doi:10.1016/j.jeconom.2013.08.012>. Standard unit root tests (ADF, Phillips-Perron) have non-standard limiting distributions when the time series is bounded. This package provides modified ADF and M-type tests (MZ-alpha, MZ-t, MSB) with p-values computed via Monte Carlo simulation of bounded Brownian motion. Supports one-sided (lower bound only) and two-sided bounds, with automatic lag selection using the MAIC criterion of Ng and Perron (2001) <doi:10.1111/1468-0262.00256>.

This package provides computational tools to generate efficient blocked and unblocked fractional factorial designs for two-level and three-level factors using the generalized Minimum Aberration (MA) criterion and related optimization algorithms. Methodological foundations include the general theory of minimum aberration as described by Cheng and Tang (2005) <doi:10.1214/009053604000001228>, and the catalogue of three-level regular fractional factorial designs developed by Xu (2005) <doi:10.1007/s00184-005-0408-x>. The main functions dol2() and dol3() generate blocked two-level and three-level fractional factorial designs, respectively, using beam search, optimization-based ranking, confounding assessment, and structured output suitable for complete factorial situations.

This package provides a GUI with which users can construct and interact with biplots.

Bindings to the blowfish password hashing algorithm <https://www.openbsd.org/papers/bcrypt-paper.pdf> derived from the OpenBSD implementation.

The purpose of this package is to fit the three Spatial Econometric Models proposed in Anselin (1988, ISBN:9024737354) in the homoscedastic and the heteroscedatic case. The fit is made through MCMC algorithms and observational working variables approach.

Ecological alteration of degraded lands can improve their sustainability by addition of large amount of biomass to soil resulting in improved soil health. Soil biological parameters (such as carbon, nitrogen and phosphorus cycling enzyme activity) are reactive to minute variations in soils [Ghosh et al. (2021) <doi:10.1016/j.ecoleng.2021.106176> ]. Hence, biological activity index combining Urease, Alkaline Phosphatase, Dehydrogenase (DHA) & Beta-Glucosidase activity will assist in detecting early changes in restored land use systems [Patidar et al. (2023) <doi:10.3389/fsufs.2023.1230156>]. This package helps to calculate Biological Activity Index (BAI) based on vectors of Land Use System/treatment and control/reference Land Use System containing four values of Urease, Alkaline Phosphatase, DHA & Beta-Glucosidase. (DHA), urease (URE), fluorescein diacetate hydrolysis (FDA) and alkaline phosphatase (ALP) activities are measured in soil samples using triphenyl tetrazolium chloride, urea, fluorescein diacetate and p-nitro phenyl-phosphate as substrates, respectively.

This package implements the Butterworth-Induced Autoregressive ('BTWAR') model, where autoregressive coefficients are obtained from analog Butterworth filter prototypes mapped into the discrete-time domain using the Matched Z-Transform. The framework establishes a structured connection between frequency-domain filter design and time-domain autoregressive modeling. Model order selection is performed via nested rolling-origin cross-validation. Method described in Bras-Geraldes, Rocha and Martins (2026) <doi:10.3390/math14030479>.

Simulating synthetic clumped isotope dataset, fitting linear regression models under Bayesian and non-Bayesian frameworks, and generating temperature reconstructions for the same two approaches. Please note that models implemented in this package are described in Roman-Palacios et al. (2021) <doi:10.1002/essoar.10507995.1>.

This package creates bivariate choropleth maps using Leaflet'. This package provides tools for visualizing the relationship between two variables through a color matrix representation on an interactive map.

The method models RNA-seq reads using a mixture of 3 beta-binomial distributions to generate posterior probabilities for genotyping bi-allelic single nucleotide polymorphisms. Elena Vigorito, Anne Barton, Costantino Pitzalis, Myles J. Lewis and Chris Wallace (2023) <doi:10.1093/bioinformatics/btad393> "BBmix: a Bayesian beta-binomial mixture model for accurate genotyping from RNA-sequencing.".

Bayesian Hierarchical beta-binomial models for modeling cell population to predictors/exposures. This package utilizes runjags to run Gibbs sampling, parallelizing the chains. Options for different covariances/relationship structures between parameters of interest.

Generate the James Blinding Index, as described in James et al (1996) <https://pubmed.ncbi.nlm.nih.gov/8841652/> and the Bang Blinding Index, as described in Bang et al (2004) <https://pubmed.ncbi.nlm.nih.gov/15020033/>. These are measures to assess whether or not satisfactory blinding has been maintained in a randomized, controlled, clinical trial. These can be generated for trial subjects, research coordinators and principal investigators, based upon standardized questionnaires that have been administered, to assess whether or not they can correctly guess to which treatment arm (e.g. placebo or treatment) subjects were assigned at randomization.

Fit and simulate bivariate correlated frailty models with proportional hazard structure. Frailty distributions, such as gamma and lognormal models are supported semiparametric procedures. Frailty variances of the two subjects can be varied or equal. Details on the models are available in book of Wienke (2011,ISBN:978-1-4200-7388-1). Bivariate gamma fit is obtained using the approach given in Kifle et al (2023) <DOI: 10.4310/22-SII738> with modifications. Lognormal fit is based on the approach by Ripatti and Palmgren (2000) <doi:10.1111/j.0006-341X.2000.01016.x>. Frailty distributions, such as gamma, inverse gaussian and power variance frailty models are supported for parametric approach.

Battery reduction is a method used in data reduction. It uses Gram-Schmidt orthogonal rotations to find out a subset of variables best representing the original set of variables.

Computation of the minimum sample size using the Average Coverage Criterion or the Average Length Criterion for estimating binomial proportions using beta prior distributions. For more details see Costa (2025) <DOI:10.1007/978-3-031-72215-8_14>.

This package provides tools for statistical analysis using the binscatter methods developed by Cattaneo, Crump, Farrell and Feng (2024) <https://nppackages.github.io/references/Cattaneo-Crump-Farrell-Feng_2024_AER.pdf>, Cattaneo, Crump, Farrell and Feng (2025) <https://nppackages.github.io/references/Cattaneo-Crump-Farrell-Feng_2025_Stata.pdf> and Cattaneo, Crump, Farrell and Feng (2026) <https://nppackages.github.io/references/Cattaneo-Crump-Farrell-Feng_2026_RESTAT.pdf>. Binscatter provides a flexible way of describing the relationship between two variables based on partitioning/binning of the independent variable of interest. binsreg(), binsqreg() and binsglm() implement binscatter least squares regression, quantile regression and generalized linear regression respectively, with particular focus on constructing binned scatter plots. They also implement robust (pointwise and uniform) inference of regression functions and derivatives thereof. binstest() implements hypothesis testing procedures for parametric functional forms of and nonparametric shape restrictions on the regression function. binspwc() implements hypothesis testing procedures for pairwise group comparison of binscatter estimators. binsregselect() implements data-driven procedures for selecting the number of bins for binscatter estimation. All the commands allow for covariate adjustment, smoothness restrictions and clustering.

Connect to the D2L Brightspace Data Sets ('BDS') API via OAuth2', download all available datasets as tidy data frames with proper types, join them using convenience functions that know the foreign key relationships, and analyse student engagement, performance, and retention with ready-made analytics functions.

This package provides methods for model selection, model averaging, and calculating metrics, such as the Gini, Theil, Mean Log Deviation, etc, on binned income data where the topmost bin is right-censored. We provide both a non-parametric method, termed the bounded midpoint estimator (BME), which assigns cases to their bin midpoints; except for the censored bins, where cases are assigned to an income estimated by fitting a Pareto distribution. Because the usual Pareto estimate can be inaccurate or undefined, especially in small samples, we implement a bounded Pareto estimate that yields much better results. We also provide a parametric approach, which fits distributions from the generalized beta (GB) family. Because some GB distributions can have poor fit or undefined estimates, we fit 10 GB-family distributions and use multimodel inference to obtain definite estimates from the best-fitting distributions. We also provide binned income data from all United States of America school districts, counties, and states.

This package provides methods for probabilistic reconciliation of hierarchical forecasts of time series. The available methods include analytical Gaussian reconciliation (Corani et al., 2021) <doi:10.1007/978-3-030-67664-3_13>, MCMC reconciliation of count time series (Corani et al., 2024) <doi:10.1016/j.ijforecast.2023.04.003>, Bottom-Up Importance Sampling (Zambon et al., 2024) <doi:10.1007/s11222-023-10343-y>, methods for the reconciliation of mixed hierarchies (Mix-Cond and TD-cond) (Zambon et al., 2024) <https://proceedings.mlr.press/v244/zambon24a.html>, analytical reconciliation with Bayesian treatment of the covariance matrix (Carrara et al., 2025) <doi: 10.48550/arXiv.2506.19554>.