Simulating multi-arm cluster-randomized, multi-site, and simple randomized trials. Includes functions for conducting multilevel analyses using both Bayesian and Frequentist methods. Supports futility and superiority analyses through Bayesian approaches, along with visualization tools to aid interpretation and presentation of results.

The core of this package is a function eDT() which enhances DT::datatable() such that it can be used to interactively modify data in shiny'. By the use of generic dplyr methods it supports many types of data storage, with relational databases ('dbplyr') being the main use case.

Diagnose, visualize, and aggregate event report level data to the event level. Users provide an event report level dataset, specify their aggregation rules, and the package produces a dataset aggregated at the event level. Also includes the Modes and Agents of Election-Related Violence in Côte d'Ivoire and Kenya (MAVERICK) dataset, an event report level dataset that records all documented instances of electoral violence from the first multiparty election to 2022 in Côte d'Ivoire (1995-2022) and Kenya (1992-2022).

This package provides a comprehensive toolkit for single-cell annotation with the CellMarker2.0 database (see Xia Li, Peng Wang, Yunpeng Zhang (2023) <doi: 10.1093/nar/gkac947>). Streamlines biological label assignment in single-cell RNA-seq data and facilitates transcriptomic analysis, including preparation of TCGA<https://portal.gdc.cancer.gov/> and GEO<https://www.ncbi.nlm.nih.gov/geo/> datasets, differential expression analysis and visualization of enrichment analysis results. Additional utility functions support various bioinformatics workflows. See Wei Cui (2024) <doi: 10.1101/2024.09.14.609619> for more details.

This package provides computational tools for working with the Extended Laplace distribution, including the probability density function, cumulative distribution function, quantile function, random variate generation based on convolution with Uniform noise and the quantile-quantile plot. Useful for modeling contaminated Laplace data and other applications in robust statistics. See Saah and Kozubowski (2025) <doi:10.1016/j.cam.2025.116588>.

This package implements a Markov Chain Monte Carlo algorithm to approximate exact conditional inference for logistic regression models. Exact conditional inference is based on the distribution of the sufficient statistics for the parameters of interest given the sufficient statistics for the remaining nuisance parameters. Using model formula notation, users specify a logistic model and model terms of interest for exact inference. See Zamar et al. (2007) <doi:10.18637/jss.v021.i03> for more details.

This package contains logic for computing sparse principal components via the EESPCA method, which is based on an approximation of the eigenvector/eigenvalue identity. Includes logic to support execution of the TPower and rifle sparse PCA methods, as well as logic to estimate the sparsity parameters used by EESPCA, TPower and rifle via cross-validation to minimize the out-of-sample reconstruction error. H. Robert Frost (2021) <doi:10.1080/10618600.2021.1987254>.

Reproducibility assessment is essential in extracting reliable scientific insights from high-throughput experiments. While the Irreproducibility Discovery Rate (IDR) method has been instrumental in assessing reproducibility, its standard implementation is constrained to handling only two replicates. Package eCV introduces an enhanced Coefficient of Variation (eCV) metric to assess the likelihood of omic features being reproducible. Additionally, it offers alternatives to the Irreproducible Discovery Rate (IDR) calculations for multi-replicate experiments. These tools are valuable for analyzing high-throughput data in genomics and other omics fields. The methods implemented in eCV are described in Gonzalez-Reymundez et al., (2023) <doi:10.1101/2023.12.18.572208>.

Empirical likelihood ratio tests for the Yang and Prentice (short/long term hazards ratio) models. Empirical likelihood tests within a Cox model, for parameters defined via both baseline hazard function and regression parameters.

Given a continuous-time dynamic network, this package allows one to fit a stochastic blockmodel where nodes belonging to the same group create interactions and non-interactions of similar lengths. This package implements the methodology described by R. Rastelli and M. Fop (2020) <doi:10.1007/s11634-020-00403-w>.

Use structural equation modeling to estimate average and conditional effects of a treatment variable on an outcome variable, taking into account multiple continuous and categorical covariates.

Pacote para a analise de experimentos havendo duas variaveis explicativas quantitativas e uma variavel dependente quantitativa. Os experimentos podem ser sem repeticoes ou com delineamento estatistico. Sao ajustados 12 modelos de regressao multipla e plotados graficos de superficie resposta (Hair JF, 2016) <ISBN:13:978-0138132637>.(Package for the analysis of experiments having two explanatory quantitative variables and one quantitative dependent variable. The experiments can be without repetitions or with a statistical design. Twelve multiple regression models are fitted and response surface graphs are plotted (Hair JF, 2016) <ISBN:13:978-0138132637>).

Collection of data sets from various assessments that can be used to evaluate psychometric models. These data sets have been analyzed in the following papers that introduced new methodology as part of the application section: Jimenez, A., Balamuta, J. J., & Culpepper, S. A. (2023) <doi:10.1111/bmsp.12307>, Culpepper, S. A., & Balamuta, J. J. (2021) <doi:10.1080/00273171.2021.1985949>, Yinghan Chen et al. (2021) <doi:10.1007/s11336-021-09750-9>, Yinyin Chen et al. (2020) <doi:10.1007/s11336-019-09693-2>, Culpepper, S. A. (2019a) <doi:10.1007/s11336-019-09683-4>, Culpepper, S. A. (2019b) <doi:10.1007/s11336-018-9643-8>, Culpepper, S. A., & Chen, Y. (2019) <doi:10.3102/1076998618791306>, Culpepper, S. A., & Balamuta, J. J. (2017) <doi:10.1007/s11336-015-9484-7>, and Culpepper, S. A. (2015) <doi:10.3102/1076998615595403>.

This package provides a flexible tool for enrichment analysis based on user-defined sets. It allows users to perform over-representation analysis of the custom sets among any specified ranked feature list, hence making enrichment analysis applicable to various types of data from different scientific fields. EnrichIntersect also enables an interactive means to visualize identified associations based on, for example, the mix-lasso model (Zhao et al., 2022 <doi:10.1016/j.isci.2022.104767>) or similar methods.

Simulate and fitting exponential multivariate Hawkes model. This package simulates a multivariate Hawkes model, introduced by Hawkes (1971) <doi:10.2307/2334319>, with an exponential kernel and fits the parameters from the data. Models with the constant parameters, as well as complex dependent structures, can also be simulated and estimated. The estimation is based on the maximum likelihood method, introduced by introduced by Ozaki (1979) <doi:10.1007/BF02480272>, with maxLik package.

Computes various effect sizes of the difference, their variance, and confidence interval. This package treats Cohen's d, Hedges d, biased/unbiased c (an effect size between a mean and a constant) and e (an effect size between means without assuming the variance equality).

This package provides tools for simulating mathematical models of infectious disease dynamics. Epidemic model classes include deterministic compartmental models, stochastic individual-contact models, and stochastic network models. Network models use the robust statistical methods of exponential-family random graph models (ERGMs) from the Statnet suite of software packages in R. Standard templates for epidemic modeling include SI, SIR, and SIS disease types. EpiModel features an API for extending these templates to address novel scientific research aims. Full methods for EpiModel are detailed in Jenness et al. (2018, <doi:10.18637/jss.v084.i08>).

Reads EXIF data using ExifTool <https://exiftool.org> and returns results as a data frame. ExifTool is a platform-independent Perl library plus a command-line application for reading, writing and editing meta information in a wide variety of files. ExifTool supports many different metadata formats including EXIF, GPS, IPTC, XMP, JFIF, GeoTIFF, ICC Profile, Photoshop IRB, FlashPix, AFCP and ID3, as well as the maker notes of many digital cameras by Canon, Casio, FLIR, FujiFilm, GE, HP, JVC/Victor, Kodak, Leaf, Minolta/Konica-Minolta, Motorola, Nikon, Nintendo, Olympus/Epson, Panasonic/Leica, Pentax/Asahi, Phase One, Reconyx, Ricoh, Samsung, Sanyo, Sigma/Foveon and Sony.

Different evidential classifiers, which provide outputs in the form of Dempster-Shafer mass functions. The methods are: the evidential K-nearest neighbor rule, the evidential neural network, radial basis function neural networks, logistic regression, feed-forward neural networks.

The nonparametric trend and its derivatives in equidistant time series (TS) with long-memory errors can be estimated. The estimation is conducted via local polynomial regression using an automatically selected bandwidth obtained by a built-in iterative plug-in algorithm or a bandwidth fixed by the user. The smoothing methods of the package are described in Letmathe, S., Beran, J. and Feng, Y., (2023) <doi:10.1080/03610926.2023.2276049>.

This package provides functions for setting up and analyzing event history data.

This package provides a lightweight implementation of functions and methods for fast and fully automatic time series modeling and forecasting using Echo State Networks (ESNs).

Bindings to edlib, a lightweight performant C/C++ library for exact pairwise sequence alignment using edit distance (Levenshtein distance). The algorithm computes the optimal alignment path, but also can be used to find only the start and/or end of the alignment path for convenience. Edlib was designed to be ultrafast and require little memory, with the capability to handle very large sequences. Three alignment methods are supported: global (Needleman-Wunsch), infix (Hybrid Wunsch), and prefix (Semi-Hybrid Wunsch). The original C/C++ library is described in "Edlib: a C/C++ library for fast, exact sequence alignment using edit distance", M. Å oÅ¡iÄ , M. Å ikiÄ , <doi:10.1093/bioinformatics/btw753>.

This package provides easy access to tidy education finance data using Bellwether's methodology to combine NCES F-33 Survey, Census Bureau Small Area Income Poverty Estimates (SAIPE), and community data from the ACS 5-Year Estimates. The package simplifies downloading, caching, and filtering education finance data by year and state, enabling researchers and analysts to explore K-12 education funding patterns, revenue sources, expenditure categories, and demographic factors across U.S. school districts.