This package provides a non-linear model, termed ACME, that reflects a parsimonious biological model for allelic contributions of cis-acting eQTLs. With non-linear least-squares algorithm the maximum likelihood parameters can be estimated. The ACME model provides interpretable effect size estimates and p-values with well controlled Type-I error.

This package provides the prediction() function, a type-safe alternative to predict() that always returns a data frame. The package currently supports common model types (e.g., "lm", "glm") from the stats package, as well as numerous other model classes from other add-on packages.

This package provides tools for data importation, recoding, and inspection. There are functions to create new project folders, R code templates, create uniquely named output directories, and to quickly obtain a visual summary for each variable in a data frame. The main feature here is the systematic implementation of the "variable key" framework for data importation and recoding.

Lambert W x F distributions are a generalized framework to analyze skewed, heavy-tailed data. It is based on an input/output system, where the output random variable (RV) Y is a non-linearly transformed version of an input RV X ~ F with similar properties as X, but slightly skewed (heavy-tailed). The transformed RV Y has a Lambert W x F distribution. This package contains functions to model and analyze skewed, heavy-tailed data the Lambert Way: simulate random samples, estimate parameters, compute quantiles, and plot/ print results nicely. The most useful function is Gaussianize, which works similarly to scale, but actually makes the data Gaussian. A do-it-yourself toolkit allows users to define their own Lambert W x MyFavoriteDistribution and use it in their analysis right away.

This package contains an efficient implementation of Sen's slope method (Sen, 1968) plus implementation of Xuebin Zhang's (Zhang, 1999) and Yue-Pilon's (Yue, 2002) pre-whitening approaches to determining trends in climate data.

This package provides a set of tools to permute multisets without loops or hash tables and to generate integer partitions. Cool-lex order is similar to colexicographical order.

This package provides an up-to-date copy of the Internet Assigned Numbers Authority (IANA) Time Zone Database. It is updated periodically to reflect changes made by political bodies to time zone boundaries, UTC offsets, and daylight saving time rules. Additionally, this package provides a C++ interface for working with the date library. date provides comprehensive support for working with dates and date-times, which this package exposes to make it easier for other R packages to utilize. Headers are provided for calendar specific calculations, along with a limited interface for time zone manipulations.

This package provides classes and methods for dense and sparse matrices and operations on them using LAPACK and SuiteSparse.

This package provides ten distributions supplementing those built into R. Inverse Gauss, Kruskal-Wallis, Kendall's Tau, Friedman's chi squared, Spearman's rho, maximum F ratio, the Pearson product moment correlation coefficient, Johnson distributions, normal scores and generalized hypergeometric distributions. In addition two random number generators of George Marsaglia are included.

This package contains functions to compute the nonparametric maximum likelihood estimator (MLE) for the bivariate distribution of (X,Y), when realizations of (X,Y) cannot be observed directly. To be more precise, we consider the situation where we observe a set of rectangles that are known to contain the unobservable realizations of (X,Y). We compute the MLE based on such a set of rectangles. The methods can also be used for univariate censored data (see data set cosmesis), and for censored data with competing risks (see data set menopause). The package also provides functions to visualize the observed data and the MLE.

This package enhances the ROI with the lp_solve solver.

This package reads and writes data files like CSV, TSV and FWF. When reading it uses a quick initial indexing step, then reads the values lazily, so only the data you actually use needs to be read. The writer formats the data in parallel and writes to disk asynchronously from formatting.

This package provides a complete unit test system and functions to implement its GUI part.

This package extends the mlr3 package with cluster analysis.

This package provides support for all calendars as specified in the Climate and Forecast (CF) Metadata Conventions for climate and forecasting data. The CF Metadata Conventions is widely used for distributing files with climate observations or projections, including the Coupled Model Intercomparison Project (CMIP) data used by climate change scientists and the Intergovernmental Panel on Climate Change (IPCC). This package specifically allows the user to work with any of the CF-compliant calendars (many of which are not compliant with POSIXt). The CF time coordinate is formally defined in the CF Metadata Conventions document.

This package provides tools to conditionally rotate or back-up files based on their size or the date of the last backup; inspired by the utility logrotate'.

This package contains the Rook specification and convenience software for building and running Rook applications. A Rook application is an R reference class object that implements a call method or an R closure that takes exactly one argument, an environment, and returns a list with three named elements: the status, the headers, and the body.

This package is an R package designed for QC, analysis, and exploration of single cell RNA-seq data. It easily enables widely-used analytical techniques, including the identification of highly variable genes, dimensionality reduction; PCA, ICA, t-SNE, standard unsupervised clustering algorithms; density clustering, hierarchical clustering, k-means, and the discovery of differentially expressed genes and markers.

The tkrplot package lets you place R graphics in a Tk, cross-platform graphical user interface toolkit widget.

This package provides functions to produce rudimentary ASCII graphics directly in the terminal window. This package provides a basic plotting function (and equivalents of curve, density, acf and barplot) as well as a boxplot function.

Iterated race is an extension of the Iterated F-race method for the automatic configuration of optimization algorithms, that is, (offline) tuning their parameters by finding the most appropriate settings given a set of instances of an optimization problem.

This package provides a unified interface to various machine learning algorithms. Confusion matrices are provided too.

This package provides a cross-platform command-line argument parser written purely in R with no external dependencies. It is useful with the Rscript front-end and facilitates turning an R script into an executable script.

This package provides a helper that tests DBI back ends for conformity to the interface.