This package contains functions for solving commonly encountered problems while programming in R. This package is intended to provide a lightweight supplement to Base R, and will be useful for almost any R user.

Enhancing T cell receptor (TCR) sequence analysis, ClusTCR2', based on ClusTCR python program, leverages Hamming distance to compare the complement-determining region three (CDR3) sequences for sequence similarity, variable gene (V gene) and length. The second step employs the Markov Cluster Algorithm to identify clusters within an undirected graph, providing a summary of amino acid motifs and matrix for generating network plots. Tailored for single-cell RNA-seq data with integrated TCR-seq information, ClusTCR2 is integrated into the Single Cell TCR and Expression Grouped Ontologies (STEGO) R application or STEGO.R'. See the two publications for more details. Sebastiaan Valkiers, Max Van Houcke, Kris Laukens, Pieter Meysman (2021) <doi:10.1093/bioinformatics/btab446>, Kerry A. Mullan, My Ha, Sebastiaan Valkiers, Nicky de Vrij, Benson Ogunjimi, Kris Laukens, Pieter Meysman (2023) <doi:10.1101/2023.09.27.559702>.

Fits a constrained regression model for an ordinal response with ordinal predictors and possibly others, Espinosa and Hennig (2019) <DOI:10.1007/s11222-018-9842-2>. The parameter estimates associated with an ordinal predictor are constrained to be monotonic. If a monotonicity direction (isotonic or antitonic) is not specified for an ordinal predictor by the user, then one of the available methods will either establish it or drop the monotonicity assumption. Two monotonicity tests are also available to test the null hypothesis of monotonicity over a set of parameters associated with an ordinal predictor.

Hansen's (1995) Covariate-Augmented Dickey-Fuller (CADF) test. The only required argument is y, the Tx1 time series to be tested. If no stationary covariate X is passed to the procedure, then an ordinary ADF test is performed. The p-values of the test are computed using the procedure illustrated in Lupi (2009).

Parameter estimation, one-step ahead forecast and new location prediction methods for spatio-temporal data.

Estimate sample sizes needed to capture target levels of genetic diversity from a population (multivariate allele frequencies) for applications like germplasm conservation and breeding efforts. Compares bootstrap samples to a full population using linear regression, employing the R-squared value to represent the proportion of diversity captured. Iteratively increases sample size until a user-defined target R-squared is met. Offers a parallelized R implementation of a previously developed python method. All ploidy levels are supported. For more details, see Sandercock et al. (2024) <doi:10.1073/pnas.2403505121>.

Monitor and trace changes in clustering solutions of accumulating datasets at successive time points. The clusters can adopt External and Internal transition at succeeding time points. The External transitions comprise of Survived, Merged, Split, Disappeared, and newly Emerged candidates. In contrast, Internal transition includes changes in location and cohesion of the survived clusters. The package uses MONIC framework developed by Spiliopoulou, Ntoutsi, Theodoridis, and Schult (2006)<doi:10.1145/1150402.1150491> .

Easily create color-coded (choropleth) maps in R. No knowledge of cartography or shapefiles needed; go directly from your geographically identified data to a highly customizable map with a single line of code! Supported geographies: U.S. states, counties, census tracts, and zip codes, world countries and sub-country regions (e.g., provinces, prefectures, etc.).

Uses non-linear regression to statistically compare two circadian rhythms. Groups are only compared if both are rhythmic (amplitude is non-zero). Performs analyses regarding mesor, phase, and amplitude, reporting on estimates and statistical differences, for each, between groups. Details can be found in Parsons et al (2020) <doi:10.1093/bioinformatics/btz730>.

Conformal time series forecasting using the caret infrastructure. It provides access to state-of-the-art machine learning models for forecasting applications. The hyperparameter of each model is selected based on time series cross-validation, and forecasting is done recursively.

To improve estimation accuracy and stability in statistical modeling, catalytic prior distributions are employed, integrating observed data with synthetic data generated from a simpler model's predictive distribution. This approach enhances model robustness, stability, and flexibility in complex data scenarios. The catalytic prior distributions are introduced by Huang et al. (2020, <doi:10.1073/pnas.1920913117>), Li and Huang (2023, <doi:10.48550/arXiv.2312.01411>).

This package provides functions to create contour-enhanced forest plots for meta-analysis, supporting binary outcomes (e.g., odds ratios, risk ratios), continuous outcomes (e.g., correlations), and prevalence estimates. Includes options for prediction intervals, customized colors, study labeling, and contour shading to highlight regions of statistical significance. Based on metafor and ggplot2'.

This package contains functions for estimating generalized parametric mixture and non-mixture cure models <doi:10.1016/j.cmpb.2022.107125>, loss of lifetime, mean residual lifetime, and crude event probabilities.

Solves multivariate least squares (MLS) problems subject to constraints on the coefficients, e.g., non-negativity, orthogonality, equality, inequality, monotonicity, unimodality, smoothness, etc. Includes flexible functions for solving MLS problems subject to user-specified equality and/or inequality constraints, as well as a wrapper function that implements 24 common constraint options. Also does k-fold or generalized cross-validation to tune constraint options for MLS problems. See ten Berge (1993, ISBN:9789066950832) for an overview of MLS problems, and see Goldfarb and Idnani (1983) <doi:10.1007/BF02591962> for a discussion of the underlying quadratic programming algorithm.

Searches for, accesses, and retrieves Statistics Canada data tables, as well as individual vectors, as tidy data frames. This package enriches the tables with metadata, deals with encoding issues, allows for bilingual English or French language data retrieval, and bundles convenience functions to make it easier to work with retrieved table data. For more efficient data access the package allows for caching data in a local database and database level filtering, data manipulation and summarizing.

This package provides an expectation maximization (EM) algorithm to fit a mixture of continuous time Markov models for use with clickstream or other sequence type data. Gallaugher, M.P.B and McNicholas, P.D. (2018) <arXiv:1802.04849>.

Computes community climate statistics for volume and mismatch using species climate niches either unscaled or scaled relative to a regional species pool. These statistics can be used to describe biogeographic patterns and infer community assembly processes. Includes a vignette outlining usage.

This package provides a simulation model and accompanying functions that support assessing silvicultural concepts on the forest estate level with a focus on the CO2 uptake by wood growth and CO2 emissions by forest operations. For achieving this, a virtual forest estate area is split into the areas covered by typical phases of the silvicultural concept of interest. Given initial area shares of these phases, the dynamics of these areas is simulated. The typical carbon stocks and flows which are known for all phases are attributed post-hoc to the areas and upscaled to the estate level. CO2 emissions by forest operations are estimated based on the amounts and dimensions of the harvested timber. Probabilities of damage events are taken into account.

Unifying an inconsistently coded categorical variable between two different time points in accordance with a mapping table. The main rule is to replicate the observation if it could be assigned to a few categories. Then using frequencies or statistical methods to approximate the probabilities of being assigned to each of them. This procedure was invented and implemented in the paper by Nasinski, Majchrowska, and Broniatowska (2020) <doi:10.24425/cejeme.2020.134747>.

Enables educational researchers and practitioners to calculate the curricular complexity of a plan of study, visualize its prerequisite structure at scale, and conduct customizable analyses. The original tool can be found at <https://curricularanalytics.org>. Additional functions to explore curriculum complexity from the literature are also included.

Fits multivariate models in an R-vine pair copula construction framework, in such a way that the conditional copula can be easily evaluated. In addition, the package implements functionality to compute or approximate the conditional expectation via the conditional copula.

Semiparametric estimation for censored time series with lower detection limit. The latent response is a sequence of stationary process with Markov property of order one. Estimation of copula parameter(COPC) and Conditional quantile estimation are included for five available copula functions. Copula selection methods based on L2 distance from empirical copula function are also included.

Formal psychological models of categorization and learning, independently-replicated data sets against which to test them, and simulation archives.

This package implements higher order likelihood-based inference for logistic and loglinear models.