The Gene Ontology (GO) Consortium <https://geneontology.org/> organizes genes into hierarchical categories based on biological process (BP), molecular function (MF) and cellular component (CC, i.e., subcellular localization). Tools such as GoMiner (see Zeeberg, B.R., Feng, W., Wang, G. et al. (2003) <doi:10.1186/gb-2003-4-4-r28>) can leverage GO to perform ontological analysis of microarray and proteomics studies, typically generating a list of significant functional categories. The significance is traditionally determined by randomizing the input gene list to computing the false discovery rate (FDR) of the enrichment p-value for each category. We explore here the novel alternative of randomizing the GO database rather than the gene list.

Provide a simple interface to Bloomberg's OpenFIGI API. Please see <https://openfigi.com> for API details and registration. You may be eligible to have an API key to accelerate your loading process.

This package provides a series of functions to call AD Model Builder (i.e., compile and run models) from within R, read the results back into R as admb objects, and provide standard accessors (i.e. coef(), vcov(), etc.).

ENA (Shaffer, D. W. (2017) Quantitative Ethnography. ISBN: 0578191687) is a method used to identify meaningful and quantifiable patterns in discourse or reasoning. ENA moves beyond the traditional frequency-based assessments by examining the structure of the co-occurrence, or connections in coded data. Moreover, compared to other methodological approaches, ENA has the novelty of (1) modeling whole networks of connections and (2) affording both quantitative and qualitative comparisons between different network models. Shaffer, D.W., Collier, W., & Ruis, A.R. (2016).

Defines submission profiles per regulatory authority with authority-specific pillar weights, decision thresholds, indicator requirements, and risk configuration. Supports the U.S. Food and Drug Administration (FDA), European Medicines Agency (EMA), Pharmaceuticals and Medical Devices Agency (PMDA), Health Canada, Therapeutic Goods Administration (TGA), and Medicines and Healthcare products Regulatory Agency (MHRA). Integrates with r4subscore and r4subrisk configuration systems.

The Regional Vulnerability Index (RVI), a statistical measure of brain structural abnormality, quantifies an individual's similarity to the expected pattern (effect size) of deficits in schizophrenia (Kochunov P, Fan F, Ryan MC, et al. (2020) <doi:10.1002/hbm.25045>).

An HTTP API client for Lemmy (<https://github.com/LemmyNet/lemmy>) in R. Code and documentation are generated from the official JavaScript client source (<https://github.com/LemmyNet/lemmy-js-client>).

The RcppClassic package provides a deprecated C++ library which facilitates the integration of R and C++. New projects should use the new Rcpp API in the Rcpp package.

Use the <https://api.nbp.pl/> API through R. Retrieve currency exchange rates and gold prices data published by the National Bank of Poland in form of convenient R objects.

This package provides functions and datasets to support Summary and Analysis of Extension Program Evaluation in R, and An R Companion for the Handbook of Biological Statistics. Vignettes are available at <https://rcompanion.org>.

Enhances the R Optimization Infrastructure ('ROI') package with the clarabel solver for solving convex cone problems. More information about clarabel can be found at <https://oxfordcontrol.github.io/ClarabelDocs/stable/>.

Interface to the ZeroMQ lightweight messaging kernel (see <https://zeromq.org/> for more information).

Client for accessing data journalism APIs from ProPublica <http://www.propublica.org/>.

Configuration management using files (YAML, JSON, INI, TXT), JSON strings, and command line arguments. Command line arguments can be used to override configuration. Period-separated command line flags are parsed as hierarchical lists. Environment variables, R global variables, and configuration values can be substituted.

Analyzing the performance of artificial intelligence (AI) systems/algorithms characterized by a search-and-report strategy. Historically observer performance has dealt with measuring radiologists performances in search tasks, e.g., searching for lesions in medical images and reporting them, but the implicit location information has been ignored. The implemented methods apply to analyzing the absolute and relative performances of AI systems, comparing AI performance to a group of human readers or optimizing the reporting threshold of an AI system. In addition to performing historical receiver operating receiver operating characteristic (ROC) analysis (localization information ignored), the software also performs free-response receiver operating characteristic (FROC) analysis, where lesion localization information is used. A book using the software has been published: Chakraborty DP: Observer Performance Methods for Diagnostic Imaging - Foundations, Modeling, and Applications with R-Based Examples, Taylor-Francis LLC; 2017: <https://www.routledge.com/Observer-Performance-Methods-for-Diagnostic-Imaging-Foundations-Modeling/Chakraborty/p/book/9781482214840>. Online updates to this book, which use the software, are at <https://dpc10ster.github.io/RJafrocQuickStart/>, <https://dpc10ster.github.io/RJafrocRocBook/> and at <https://dpc10ster.github.io/RJafrocFrocBook/>. Supported data collection paradigms are the ROC, FROC and the location ROC (LROC). ROC data consists of single ratings per images, where a rating is the perceived confidence level that the image is that of a diseased patient. An ROC curve is a plot of true positive fraction vs. false positive fraction. FROC data consists of a variable number (zero or more) of mark-rating pairs per image, where a mark is the location of a reported suspicious region and the rating is the confidence level that it is a real lesion. LROC data consists of a rating and a location of the most suspicious region, for every image. Four models of observer performance, and curve-fitting software, are implemented: the binormal model (BM), the contaminated binormal model (CBM), the correlated contaminated binormal model (CORCBM), and the radiological search model (RSM). Unlike the binormal model, CBM, CORCBM and RSM predict proper ROC curves that do not inappropriately cross the chance diagonal. Additionally, RSM parameters are related to search performance (not measured in conventional ROC analysis) and classification performance. Search performance refers to finding lesions, i.e., true positives, while simultaneously not finding false positive locations. Classification performance measures the ability to distinguish between true and false positive locations. Knowing these separate performances allows principled optimization of reader or AI system performance. This package supersedes Windows JAFROC (jackknife alternative FROC) software V4.2.1, <https://github.com/dpc10ster/WindowsJafroc>. Package functions are organized as follows. Data file related function names are preceded by Df', curve fitting functions by Fit', included data sets by dataset', plotting functions by Plot', significance testing functions by St', sample size related functions by Ss', data simulation functions by Simulate and utility functions by Util'. Implemented are figures of merit (FOMs) for quantifying performance and functions for visualizing empirical or fitted operating characteristics: e.g., ROC, FROC, alternative FROC (AFROC) and weighted AFROC (wAFROC) curves. For fully crossed study designs significance testing of reader-averaged FOM differences between modalities is implemented via either Dorfman-Berbaum-Metz or the Obuchowski-Rockette methods. Also implemented is single treatment analysis, which allows comparison of performance of a group of radiologists to a specified value, or comparison of AI to a group of radiologists interpreting the same cases. Crossed-modality analysis is implemented wherein there are two crossed treatment factors and the aim is to determined performance in each treatment factor averaged over all levels of the second factor. Sample size estimation tools are provided for ROC and FROC studies; these use estimates of the relevant variances from a pilot study to predict required numbers of readers and cases in a pivotal study to achieve the desired power. Utility and data file manipulation functions allow data to be read in any of the currently used input formats, including Excel, and the results of the analysis can be viewed in text or Excel output files. The methods are illustrated with several included datasets from the author's collaborations. This update includes improvements to the code, some as a result of user-reported bugs and new feature requests, and others discovered during ongoing testing and code simplification.

Implementation of the affine-invariant method of Goodman & Weare (2010) <DOI:10.2140/camcos.2010.5.65>, a method of producing Monte-Carlo samples from a target distribution.

REDUCE is a portable general-purpose computer algebra system supporting scalar, vector, matrix and tensor algebra, symbolic differential and integral calculus, arbitrary precision numerical calculations and output in LaTeX format. REDUCE is based on Lisp and is available on the two dialects Portable Standard Lisp ('PSL') and Codemist Standard Lisp ('CSL'). The redcas package provides an interface for executing arbitrary REDUCE code interactively from R', returning output as character vectors. R code and REDUCE code can be interspersed. It also provides a specialized function for calling the REDUCE feature for solving systems of equations, returning the output as an R object designed for the purpose. A further specialized function uses REDUCE features to generate LaTeX output and post-processes this for direct use in LaTeX documents, e.g. using Sweave'.

Provide color schemes for maps (and other graphics) based on the color palettes of several Microsoft(r) products. Forked from RColorBrewer v1.1-2.

Ranking of Alternatives through Functional mapping of criterion sub-intervals into a Single Interval Method is designed to perform multi-criteria decision-making (MCDM), developed by Mališa Žižovic in 2020 (<doi:10.3390/math8061015>). It calculates the final sorted rankings based on a decision matrix where rows represent alternatives and columns represent criteria. The method uses: - A numeric vector of weights for each criterion (the sum of weights must be 1). - A numeric vector of ideal values for each criterion. - A numeric vector of anti-ideal values for each criterion. - Numeric values representing the extent to which the ideal value is preferred over the anti-ideal value, and the extent to which the anti-ideal value is considered worse. The function standardizes the decision matrix, normalizes the data, applies weights, and returns the final sorted rankings.

Facilities for working with Atlantis box-geometry model (BGM) files. Atlantis is a deterministic, biogeochemical, whole-of-ecosystem model. Functions are provided to read from BGM files directly, preserving their internal topology, as well as helper functions to generate spatial data from these mesh forms. This functionality aims to simplify the creation and modification of box and geometry as well as the ability to integrate with other data sources.

Create and manipulate hypergraph objects. This early version of rhype allows for the output of matrices associated with the hypergraphs themselves. It also uses these matrices to calculate hypergraph spectra and perform spectral comparison. Functionality coming soon includes calculation of hyperpaths and hypergraph centrality measures.

This package implements popular methods for matching in time-varying observational studies. Matching is difficult in this scenario because participants can be treated at different times which may have an influence on the outcomes. The core methods include: "Balanced Risk Set Matching" from Li, Propert, and Rosenbaum (2011) <doi:10.1198/016214501753208573> and "Propensity Score Matching with Time-Dependent Covariates" from Lu (2005) <doi:10.1111/j.1541-0420.2005.00356.x>. Some functions use the Gurobi optimization back-end to improve the optimization problem speed; the gurobi R package and associated software can be downloaded from <https://www.gurobi.com> after obtaining a license.

Wraps tiny_obj_loader C++ library for reading the Wavefront OBJ 3D file format including both mesh objects and materials files. The resultant R objects are either structured to match the tiny_obj_loader internal data representation or in a form directly compatible with the rgl package.

This package provides a series of functions that allow users to access the LinkedIn API to get information about connections, search for people and jobs, share updates with their network, and create group discussions. For more information about using the API please visit <https://developer.linkedin.com/>.