View 2D/3D sections, contour plots, mesh of excursion sets for computer experiments designs, surrogates or test functions.

This package provides a collection of functions to estimate parameters of a diffusion model via a D*M analysis. Build in models are: the Ratcliff diffusion model, the RWiener diffusion model, and Linear Ballistic Accumulator models. Custom models functions can be specified as long as they have a density function.

Statistical and graphical tools for detecting and measuring discrimination and bias, be it racial, gender, age or other. Detection and remediation of bias in machine learning algorithms. Python interfaces available.

DEploid (Zhu et.al. 2018 <doi:10.1093/bioinformatics/btx530>) is designed for deconvoluting mixed genomes with unknown proportions. Traditional phasing programs are limited to diploid organisms. Our method modifies Li and Stephenâ s algorithm with Markov chain Monte Carlo (MCMC) approaches, and builds a generic framework that allows haloptype searches in a multiple infection setting. This package provides R functions to support data analysis and results interpretation.

Access the Google Data Commons API V2 <https://docs.datacommons.org/api/rest/v2/>. Data Commons provides programmatic access to statistical and demographic data from dozens of sources organized in a knowledge graph.

This package implements survival proximity score matching in multi-state survival models. Includes tools for simulating survival data and estimating transition-specific coxph models with frailty terms. The primary methodological work on multistate censored data modeling using propensity score matching has been published by Bhattacharjee et al.(2024) <doi:10.1038/s41598-024-54149-y>.

This package provides a set of algorithms based on Quinn et al. (1991) <doi:10.1002/hyp.3360050106> for processing river network and digital elevation data to build implementations of Dynamic TOPMODEL, a semi-distributed hydrological model proposed in Beven and Freer (2001) <doi:10.1002/hyp.252>. The dynatop package implements simulation code for Dynamic TOPMODEL based on the output of dynatopGIS'.

Create and manage fault-tolerant task queues for the foreach package using the Redis key/value database.

Distribution (S4-)classes for elliptically contoured distributions (based on package distr').

This package provides tools for working with a new versatile discrete distribution, the db ("discretised Beta") distribution. This package provides density (probability), distribution, inverse distribution (quantile) and random data generation functions for the db family. It provides functions to effect conveniently maximum likelihood estimation of parameters, and a variety of useful plotting functions. It provides goodness of fit tests and functions to calculate the Fisher information, different estimates of the hessian of the log likelihood and Monte Carlo estimation of the covariance matrix of the maximum likelihood parameter estimates. In addition it provides analogous tools for working with the beta-binomial distribution which has been proposed as a competitor to the db distribution.

Solving large scale distance weighted discrimination. The main algorithm is a symmetric Gauss-Seidel based alternating direction method of multipliers (ADMM) method. See Lam, X.Y., Marron, J.S., Sun, D.F., and Toh, K.C. (2018) <doi:10.48550/arXiv.1604.05473> for more details.

This package provides a grammar of data manipulation with data.table', providing a consistent a series of utility functions that help you solve the most common data manipulation challenges.

Edit and validate taxonomic data in compliance with Darwin Core standards (Darwin Core Taxon class <https://dwc.tdwg.org/terms/#taxon>).

Description of statistical associations between variables : measures of local and global association between variables (phi, Cramér V, correlations, eta-squared, Goodman and Kruskal tau, permutation tests, etc.), multiple graphical representations of the associations between variables (using ggplot2') and weighted statistics.

An R package for iterative and batched record linkage, and applying epidemiological case definitions. diyar can be used for deterministic and probabilistic record linkage, or multistage record linkage combining both approaches. It features the implementation of nested match criteria, and mechanisms to address missing data and conflicting matches during stepwise record linkage. Case definitions are implemented by assigning records to groups based on match criteria such as person or place, and overlapping time or duration of events e.g. sample collection dates or periods of hospital stays. Matching records are assigned a unique group ID. Index and duplicate records are removed or further analyses as required.

The rapid development of single-cell transcriptomic technologies has helped uncover the cellular heterogeneity within cell populations. However, bulk RNA-seq continues to be the main workhorse for quantifying gene expression levels due to technical simplicity and low cost. To most effectively extract information from bulk data given the new knowledge gained from single-cell methods, we have developed a novel algorithm to estimate the cell-type composition of bulk data from a single-cell RNA-seq-derived cell-type signature. Comparison with existing methods using various real RNA-seq data sets indicates that our new approach is more accurate and comprehensive than previous methods, especially for the estimation of rare cell types. More importantly,our method can detect cell-type composition changes in response to external perturbations, thereby providing a valuable, cost-effective method for dissecting the cell-type-specific effects of drug treatments or condition changes. As such, our method is applicable to a wide range of biological and clinical investigations. Dampened weighted least squares ('DWLS') is an estimation method for gene expression deconvolution, in which the cell-type composition of a bulk RNA-seq data set is computationally inferred. This method corrects common biases towards cell types that are characterized by highly expressed genes and/or are highly prevalent, to provide accurate detection across diverse cell types. See: <https://www.nature.com/articles/s41467-019-10802-z.pdf> for more information about the development of DWLS and the methods behind our functions.

This package provides a wrapper for the ZEIT ONLINE Content API, available at <http://developer.zeit.de>. diezeit gives access to articles and corresponding metadata from the ZEIT archive and from ZEIT ONLINE. A personal API key is required for usage.

The FBED and mmpc variable selection algorithms have been implemented using the distance correlation. The references include: Tsamardinos I., Aliferis C. F. and Statnikov A. (2003). "Time and sample efficient discovery of Markovblankets and direct causal relations". In Proceedings of the ninth ACM SIGKDD international Conference. <doi:10.1145/956750.956838>. Borboudakis G. and Tsamardinos I. (2019). "Forward-backward selection with early dropping". Journal of Machine Learning Research, 20(8): 1--39. <doi:10.48550/arXiv.1705.10770>. Huo X. and Szekely G.J. (2016). "Fast computing for distance covariance". Technometrics, 58(4): 435--447. <doi:10.1080/00401706.2015.1054435>.

Data depth concept offers a variety of powerful and user friendly tools for robust exploration and inference for multivariate data. The offered techniques may be successfully used in cases of lack of our knowledge on parametric models generating data due to their nature. The package consist of among others implementations of several data depth techniques involving multivariate quantile-quantile plots, multivariate scatter estimators, multivariate Wilcoxon tests and robust regressions.

This package provides a way to apply Distance-Based Common Spatial Patterns (DB-CSP) techniques in different fields, both classical Common Spatial Patterns (CSP) as well as DB-CSP. The method is composed of two phases: applying the DB-CSP algorithm and performing a classification. The main idea behind the CSP is to use a linear transform to project data into low-dimensional subspace with a projection matrix, in such a way that each row consists of weights for signals. This transformation maximizes the variance of two-class signal matrices.The dbcsp object is created to compute the projection vectors. For exploratory and descriptive purpose, plot and boxplot functions can be used. Functions train, predict and selectQ are implemented for the classification step.

This package provides density, distribution function, quantile function and random generation for the split normal and split-t distributions, and computes their mean, variance, skewness and kurtosis for the two distributions (Li, F, Villani, M. and Kohn, R. (2010) <doi:10.1016/j.jspi.2010.04.031>).

The Demographic Table in R combines contingency table for categorical variables, mean and standard deviation for continuous variables. t-test, chi-square test and Fisher's exact test calculated the p-value of two groups. The standardized mean difference were performed with 95 % confident interval, and writing table into document file.

Clustered or multilevel data structures are common in the assessment of differential item functioning (DIF), particularly in the context of large-scale assessment programs. This package allows users to implement extensions of the Mantel-Haenszel DIF detection procedures in the presence of multilevel data based on the work of Begg (1999) <doi:10.1111/j.0006-341X.1999.00302.x>, Begg & Paykin (2001) <doi:10.1080/00949650108812115>, and French & Finch (2013) <doi:10.1177/0013164412472341>.

This package provides functions for discordant kinship modeling (and other sibling-based quasi-experimental designs). Contains data restructuring functions and functions for generating biometrically informed data for kin pairs. See [Garrison and Rodgers, 2016 <doi:10.1016/j.intell.2016.08.008>], [Sims, Trattner, and Garrison, 2024 <doi:10.3389/fpsyg.2024.1430978>] for empirical examples, and Garrison and colleagues for theoretical work <https://osf.io/zpdwt/>.