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This package provides a collection of several pharmacovigilance signal detection methods based on adaptive lasso. Additional lasso-based and propensity score-based signal detection approaches are also supplied. See Courtois et al <doi:10.1186/s12874-021-01450-3>.
This package provides simple assertions with sensible defaults and customisable error messages. It offers convenient assertion call wrappers and a general assert function that can handle any condition. Default error messages are user friendly and easily customized with inline code evaluation and styling powered by the cli package.
This package provides different functionalities and calculations used in the world of basketball to analyze the statistics of the players, the statistics of the teams, the statistics of the quintets and the statistics of the plays. For more details of the calculations included in the package can be found in the book Basketball on Paper written by Dean Oliver.
Data from the anxiety and confinement study from Alvarado-Aravena et al. (2022) <doi:10.3390/bs12100398>.
Estimates the attributable fraction in different sampling designs adjusted for measured confounders using logistic regression (cross-sectional and case-control designs), conditional logistic regression (matched case-control design), Cox proportional hazard regression (cohort design with time-to- event outcome), gamma-frailty model with a Weibull baseline hazard and instrumental variables analysis. An exploration of the AF with a genetic exposure can be found in the package AFheritability Dahlqwist E et al. (2019) <doi:10.1007/s00439-019-02006-8>.
This package provides a systematic framework for neural networkâ based model selection and forecasting using single hidden layer feed-forward networks. It evaluates all possible combinations of predictor variables and hidden layer configurations, selecting the optimal model based on predictive accuracy criteria such as root mean squared error (RMSE) and mean absolute percentage error (MAPE). Predictors are automatically standardized, and model performance is assessed using out-of-sample validation. The package is designed for empirical modelling and forecasting in economics, agriculture, trade, climate, and related applied research domains where nonlinear relationships and robust predictive performance are of primary interest.
An interface for data processing, building models, predicting values and analysing outcomes. Fitting Linear Models, Robust Fitting of Linear Models, k-Nearest Neighbor Classification, 1-Nearest Neighbor Classification, and Conditional Inference Trees are available.
In fields such as ecology, microbiology, and genomics, non-Euclidean distances are widely applied to describe pairwise dissimilarity between samples. Given these pairwise distances, principal coordinates analysis (PCoA) is commonly used to construct a visualization of the data. However, confounding covariates can make patterns related to the scientific question of interest difficult to observe. We provide aPCoA as an easy-to-use tool to improve data visualization in this context, enabling enhanced presentation of the effects of interest. Details are described in Yushu Shi, Liangliang Zhang, Kim-Anh Do, Christine Peterson and Robert Jenq (2020) Bioinformatics, Volume 36, Issue 13, 4099-4101.
The irregularly-spaced data are interpolated onto regular latitude-longitude grids by weighting each station according to its distance and angle from the center of a search radius. In addition to this, we also provide a simple way (Jones and Hulme, 1996) to grid the irregularly-spaced data points onto regular latitude-longitude grids by averaging all stations in grid-boxes. This study was supported by the National Natural Science Foundation of China (NSFC, Grant No. 42205177).
An interactive document on the topic of one-way and two-way analysis of variance using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://tinyurl.com/ANOVAStatsTool>.
Statistical procedures to perform stability analysis in plant breeding and to identify stable genotypes under diverse environments. It is possible to calculate coefficient of homeostaticity by Khangildin et al. (1979), variance of specific adaptive ability by Kilchevsky&Khotyleva (1989), weighted homeostaticity index by Martynov (1990), steadiness of stability index by Udachin (1990), superiority measure by Lin&Binn (1988) <doi:10.4141/cjps88-018>, regression on environmental index by Erberhart&Rassel (1966) <doi:10.2135/cropsci1966.0011183X000600010011x>, Tai's (1971) stability parameters <doi:10.2135/cropsci1971.0011183X001100020006x>, stability variance by Shukla (1972) <doi:10.1038/hdy.1972.87>, ecovalence by Wricke (1962), nonparametric stability parameters by Nassar&Huehn (1987) <doi:10.2307/2531947>, Francis&Kannenberg's parameters of stability (1978) <doi:10.4141/cjps78-157>.
Considering an (n x m) data matrix X, this package is based on the method proposed by Gower, Groener, and Velden (2010) <doi:10.1198/jcgs.2010.07134>, and utilize the resulting matrices from the extended version of the NIPALS decomposition to determine n triangles whose areas are used to visually estimate the elements of a specific column of X. After a 90-degree rotation of the sample points, the triangles are drawn regarding the following points: 1.the origin of the axes; 2.the sample points; 3. the vector endpoint representing some variable.
This package provides functions to access data from public RESTful APIs including the ArgentinaDatos API', REST Countries API', and World Bank API related to Argentina's exchange rates, inflation, political figures, holidays, economic indicators, and general country-level statistics. Additionally, the package includes curated datasets related to Argentina, covering topics such as economic indicators, biodiversity, agriculture, human rights, genetic data, and consumer prices. The package supports research and analysis focused on Argentina by integrating open APIs with high-quality datasets from various domains. For more details on the APIs, see: ArgentinaDatos API <https://argentinadatos.com/>, REST Countries API <https://restcountries.com/>, and World Bank API <https://datahelpdesk.worldbank.org/knowledgebase/articles/889392>.
An interactive shiny application for performing non-compartmental analysis (NCA) on pre-clinical and clinical pharmacokinetic data. The package builds on PKNCA for core estimators and provides interactive visualizations, CDISC outputs ('ADNCA', PP', ADPP') and configurable TLGs (tables, listings, and graphs). Typical use cases include exploratory analysis, validation, reporting or teaching/demonstration of NCA methods. Methods and core estimators are described in Denney, Duvvuri, and Buckeridge (2015) "Simple, Automatic Noncompartmental Analysis: The PKNCA R Package" <doi:10.1007/s10928-015-9432-2>.
Package that simulates adaptive (multi-arm, multi-stage) clinical trials using adaptive stopping, adaptive arm dropping, and/or adaptive randomisation. Developed as part of the INCEPT (Intensive Care Platform Trial) project (<https://incept.dk/>), primarily supported by a grant from Sygeforsikringen "danmark" (<https://www.sygeforsikring.dk/>).
Estimate age-depth models from stratigraphic and sedimentological data, and transform data between the time and stratigraphic domain.
Annuity Random Interest Rates proposes different techniques for the approximation of the present and final value of a unitary annuity-due or annuity-immediate considering interest rate as a random variable. Cruz Rambaud et al. (2017) <doi:10.1007/978-3-319-54819-7_16>. Cruz Rambaud et al. (2015) <doi:10.23755/rm.v28i1.25>.
Enables to compute the statistical indices of affluence (richness) with bootstrap errors, and inequality and polarization indices. Moreover, gives the possibility of calculation of affluence line. Some simple errors are fixed and it works with new version of Spatial Statistics packaged.
This package provides functions are designed to facilitate access to and utility with large scale, publicly available environmental data in R. The package contains functions for downloading raw data files from web URLs (download_data()), processing the raw data files into clean spatial objects (process_covariates()), and extracting values from the spatial data objects at point and polygon locations (calculate_covariates()). These functions call a series of source-specific functions which are tailored to each data sources/datasets particular URL structure, data format, and spatial/temporal resolution. The functions are tested, versioned, and open source and open access. For sum_edc() method details, see Messier, Akita, and Serre (2012) <doi:10.1021/es203152a>.
Compute the R-squared measure under the accelerated failure time (AFT) models proposed in Chan et. al. (2018) <doi:10.1080/03610918.2016.1177072>.
This package implements a framework for creating boxplots where the whisker lengths are determined by formal multiple testing procedures, making them adaptive to sample size and data characteristics. The function bh_boxplot() generates boxplots that control the False Discovery Rate (FDR) via the Benjamini-Hochberg procedure, and the function holm_boxplot() generates boxplots that control the Family-Wise Error Rate (FWER) via the Holm procedure. The methods are based on the framework in Gang, Lin, and Tong (2025) <doi:10.48550/arXiv.2510.20259>.
Create data that displays generative art when mapped into a ggplot2 plot. Functionality includes specialized data frame creation for geometric shapes, tools that define artistic color palettes, tools for geometrically transforming data, and other miscellaneous tools that are helpful when using ggplot2 for generative art.
This package implements wavelet-based approaches for describing population admixture. Principal Components Analysis (PCA) is used to define the population structure and produce a localized admixture signal for each individual. Wavelet summaries of the PCA output describe variation present in the data and can be related to population-level demographic processes. For more details, see J Sanderson, H Sudoyo, TM Karafet, MF Hammer and MP Cox. 2015. Reconstructing past admixture processes from local genomic ancestry using wavelet transformation. Genetics 200:469-481 <doi:10.1534/genetics.115.176842>.
The aligned rank transform for nonparametric factorial ANOVAs as described by Wobbrock, Findlater, Gergle, and Higgins (2011) <doi:10.1145/1978942.1978963>. Also supports aligned rank transform contrasts as described by Elkin, Kay, Higgins, and Wobbrock (2021) <doi:10.1145/3472749.3474784>.