Data and analysis from an experiment with improving touch typing speed, using the tDCS PlatoWork headset produced by PlatoScience.

This package provides functionality for quality control processing and statistical analysis of mass spectrometry (MS) omics data, in particular proteomic (either at the peptide or the protein level), lipidomic, and metabolomic data, as well as RNA-seq based count data and nuclear magnetic resonance (NMR) data. This includes data transformation, specification of groups that are to be compared against each other, filtering of features and/or samples, data normalization, data summarization (correlation, PCA), and statistical comparisons between defined groups. Implements methods described in: Webb-Robertson et al. (2014) <doi:10.1074/mcp.M113.030932>. Webb-Robertson et al. (2011) <doi:10.1002/pmic.201100078>. Matzke et al. (2011) <doi:10.1093/bioinformatics/btr479>. Matzke et al. (2013) <doi:10.1002/pmic.201200269>. Polpitiya et al. (2008) <doi:10.1093/bioinformatics/btn217>. Webb-Robertson et al. (2010) <doi:10.1021/pr1005247>.

Generate nicely formatted HTML tables to display estimation results for pharmacometric models.

Power estimation and sample size calculation for 10X Visium Spatial Transcriptomics data to detect differential expressed genes between two conditions based on bootstrap resampling. See Shui et al. (2025) <doi:10.1371/journal.pcbi.1013293> for method details.

Implementation of assumption-lean and data-adaptive post-prediction inference (POPInf), for valid and efficient statistical inference based on data predicted by machine learning. See Miao, Miao, Wu, Zhao, and Lu (2023) <arXiv:2311.14220>.

This package provides a suite of multivariate methods and data visualization tools to implement profile analysis and cross-validation techniques described in Davison & Davenport (2002) <DOI: 10.1037/1082-989X.7.4.468>, Bulut (2013), and other published and unpublished resources. The package includes routines to perform criterion-related profile analysis, profile analysis via multidimensional scaling, moderated profile analysis, profile analysis by group, and a within-person factor model to derive score profiles.

Performance metric provides different performance measures like mean squared error, root mean square error, mean absolute deviation, mean absolute percentage error etc. of a fitted model. These can provide a way for forecasters to quantitatively compare the performance of competing models. For method details see (i) Pankaj Das (2020) <http://krishi.icar.gov.in/jspui/handle/123456789/44138>.

Bindings for Poisson regression models for use with the parsnip package. Models include simple generalized linear models, Bayesian models, and zero-inflated Poisson models (Zeileis, Kleiber, and Jackman (2008) <doi:10.18637/jss.v027.i08>).

The PP package includes estimation of (MLE, WLE, MAP, EAP, ROBUST) person parameters for the 1,2,3,4-PL model and the GPCM (generalized partial credit model). The parameters are estimated under the assumption that the item parameters are known and fixed. The package is useful e.g. in the case that items from an item pool / item bank with known item parameters are administered to a new population of test-takers and an ability estimation for every test-taker is needed.

Calculate Plant Stress Response Index (PSRI) from time-series germination data with optional radicle vigor integration. Built on the methodological foundation of the Osmotic Stress Response Index (OSRI) framework developed by Walne et al. (2020) <doi:10.1002/agg2.20087>. Provides clean, direct PSRI calculations suitable for agricultural research and statistical analysis. Note: This package implements methodology currently under peer review. Please contact the author before publication using this approach.

Spectral emission data for some frequently used light emitting diodes available as electronic components. Part of the r4photobiology suite, Aphalo P. J. (2015) <doi:10.19232/uv4pb.2015.1.14>.

The function pointdensity returns a density count and the temporal average for every point in the original list. The dataframe returned includes four columns: lat, lon, count, and date_avg. The "lat" column is the original latitude data; the "lon" column is the original longitude data; the "count" is the density count of the number of points within a radius of radius*grid_size (the neighborhood); and the date_avg column includes the average date of each point in the neighborhood.

This package provides a unified framework for generating, submitting, and analyzing pairwise comparisons of writing quality using large language models (LLMs). The package supports live and/or batch evaluation workflows across multiple providers ('OpenAI', Anthropic', Google Gemini', Together AI', and locally-hosted Ollama models), includes bias-tested prompt templates and a flexible template registry, and offers tools for constructing forward and reversed comparison sets to analyze consistency and positional bias. Results can be modeled using Bradleyâ Terry (1952) <doi:10.2307/2334029> or Elo rating methods to derive writing quality scores. For information on the method of pairwise comparisons, see Thurstone (1927) <doi:10.1037/h0070288> and Heldsinger & Humphry (2010) <doi:10.1007/BF03216919>. For information on Elo ratings, see Clark et al. (2018) <doi:10.1371/journal.pone.0190393>.

Handles and formats author information in scientific writing in R Markdown and Quarto'. plume provides easy-to-use and flexible tools for inserting author data in YAML as well as generating author and contribution lists (among others) as strings from tabular data.

This package provides data set and function for exploration of Multiple Indicator Cluster Survey (MICS) 2017-18 data for Punjab, Pakistan. The results of the present survey are critically important for the purposes of SDG monitoring, as the survey produces information on 32 global SDG indicators. The data was collected from 53,840 households selected at the second stage with systematic random sampling out of a sample of 2,692 clusters selected using Probability Proportional to size sampling. Six questionnaires were used in the survey: (1) a household questionnaire to collect basic demographic information on all de jure household members (usual residents), the household, and the dwelling; (2) a water quality testing questionnaire administered in three households in each cluster of the sample; (3) a questionnaire for individual women administered in each household to all women age 15-49 years; (4) a questionnaire for individual men administered in every second household to all men age 15-49 years; (5) an under-5 questionnaire, administered to mothers (or caretakers) of all children under 5 living in the household; and (6) a questionnaire for children age 5-17 years, administered to the mother (or caretaker) of one randomly selected child age 5-17 years living in the household.

Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008) <https://www.facm.ucl.ac.be/cooperation/Vietnam/WBI-Vietnam-October-2011/Modelling/Monolix32_PKPD_library.pdf>); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).

The Pearson-ICA algorithm is a mutual information-based method for blind separation of statistically independent source signals. It has been shown that the minimization of mutual information leads to iterative use of score functions, i.e. derivatives of log densities. The Pearson system allows adaptive modeling of score functions. The flexibility of the Pearson system makes it possible to model a wide range of source distributions including asymmetric distributions. The algorithm is designed especially for problems with asymmetric sources but it works for symmetric sources as well.

Principal component of explained variance (PCEV) is a statistical tool for the analysis of a multivariate response vector. It is a dimension- reduction technique, similar to Principal component analysis (PCA), that seeks to maximize the proportion of variance (in the response vector) being explained by a set of covariates.

This package provides tools for exploring projection pursuit classification tree using various projection pursuit indexes.

Assessment for statistically-based PPQ sampling plan, including calculating the passing probability, optimizing the baseline and high performance cutoff points, visualizing the PPQ plan and power dynamically. The analytical idea is based on the simulation methods from the textbook Burdick, R. K., LeBlond, D. J., Pfahler, L. B., Quiroz, J., Sidor, L., Vukovinsky, K., & Zhang, L. (2017). Statistical Methods for CMC Applications. In Statistical Applications for Chemistry, Manufacturing and Controls (CMC) in the Pharmaceutical Industry (pp. 227-250). Springer, Cham.

Computes the All-Resolution Inference method in the permutation framework, i.e., simultaneous lower confidence bounds for the number of true discoveries. <doi:10.1002/sim.9725>.

Efficient statistical inference of two-sample MR (Mendelian Randomization) analysis. It can account for the correlated instruments and the horizontal pleiotropy, and can provide the accurate estimates of both causal effect and horizontal pleiotropy effect as well as the two corresponding p-values. There are two main functions in the PPMR package. One is PMR_individual() for individual level data, the other is PMR_summary() for summary data.

This package provides tools to compute unbiased pleiotropic heritability estimates of complex diseases from genome-wide association studies (GWAS) summary statistics. We estimate pleiotropic heritability from GWAS summary statistics by estimating the proportion of variance explained from an estimated genetic correlation matrix (Bulik-Sullivan et al. 2015 <doi:10.1038/ng.3406>) and employing a Monte-Carlo bias correction procedure to account for sampling noise in genetic correlation estimates.

Defines functions to describe regression models using only pre-computed summary statistics (i.e. means, variances, and covariances) in place of individual participant data. Possible models include linear models for linear combinations, products, and logical combinations of phenotypes. Implements methods presented in Wolf et al. (2021) <doi:10.3389/fgene.2021.745901> Wolf et al. (2020) <doi:10.1142/9789811215636_0063> and Gasdaska et al. (2019) <doi:10.1142/9789813279827_0036>.