EQ-5D is a popular health related quality of life instrument used in the clinical and economic evaluation of health care. Developed by the EuroQol group <https://euroqol.org/>, the instrument consists of two components: health state description and evaluation. For the description component a subject self-rates their health in terms of five dimensions; mobility, self-care, usual activities, pain/discomfort, and anxiety/depression using either a three-level (EQ-5D-3L, <https://euroqol.org/information-and-support/euroqol-instruments/eq-5d-3l/>) or a five-level (EQ-5D-5L, <https://euroqol.org/information-and-support/euroqol-instruments/eq-5d-5l/>) scale. Frequently the scores on these five dimensions are converted to a single utility index using country specific value sets, which can be used in the clinical and economic evaluation of health care as well as in population health surveys. The eq5d package provides methods to calculate index scores from a subject's dimension scores. 33 TTO and 11 VAS EQ-5D-3L value sets including those for countries in Szende et al (2007) <doi:10.1007/1-4020-5511-0> and Szende et al (2014) <doi:10.1007/978-94-007-7596-1>, 48 EQ-5D-5L EQ-VT value sets, the EQ-5D-5L crosswalk value sets developed by van Hout et al. (2012) <doi:10.1016/j.jval.2012.02.008>, the crosswalk value sets for Bermuda, Jordan and Russia and the van Hout (2021) reverse crosswalk value sets. 12 EQ-5D-Y3L value sets are also included as are the NICE DSU age-sex based EQ-5D-3L to EQ-5D-5L and EQ-5D-5L to EQ-5D-3L mappings. Methods are also included for the analysis of EQ-5D profiles, including those from the book "Methods for Analyzing and Reporting EQ-5D data" by Devlin et al. (2020) <doi:10.1007/978-3-030-47622-9>. Additionally a shiny web tool is included to enable the calculation, visualisation and automated statistical analysis of EQ-5D data via a web browser using EQ-5D dimension scores stored in CSV or Excel files.

Pupillometry offers a non-invasive window into the mind and has been used extensively as a psychophysiological readout of arousal signals linked with cognitive processes like attention, stress, and emotional states [Clewett et al. (2020) <doi:10.1038/s41467-020-17851-9>; Kret & Sjak-Shie (2018) <doi:10.3758/s13428-018-1075-y>; Strauch (2024) <doi:10.1016/j.tins.2024.06.002>]. Yet, despite decades of pupillometry research, many established packages and workflows to date lack design patterns based on Findability, Accessibility, Interoperability, and Reusability (FAIR) principles [see Wilkinson et al. (2016) <doi:10.1038/sdata.2016.18>]. eyeris provides a modular, performant, and extensible preprocessing framework for pupillometry data with BIDS-like organization and interactive output reports [Esteban et al. (2019) <doi:10.1038/s41592-018-0235-4>; Gorgolewski et al. (2016) <doi:10.1038/sdata.2016.44>]. Development was supported, in part, by the Stanford Wu Tsai Human Performance Alliance, Stanford Ric Weiland Graduate Fellowship, Stanford Center for Mind, Brain, Computation and Technology, NIH National Institute on Aging Grants (R01-AG065255, R01-AG079345), NSF GRFP (DGE-2146755), McKnight Brain Research Foundation Clinical Translational Research Scholarship in Cognitive Aging and Age-Related Memory Loss, American Brain Foundation, and the American Academy of Neurology.

This package implements the exponential Factor Copula Model (eFCM) of Castro-Camilo, D. and Huser, R. (2020) for spatial extremes, with tools for dependence estimation, tail inference, and visualization. The package supports likelihood-based inference, Gaussian process modeling via Matérn covariance functions, and bootstrap uncertainty quantification. See Castro-Camilo and Huser (2020) <doi:10.1080/01621459.2019.1647842>.

Analysis and visualization of similarities between epilepsy ontologies based on text mining results by comparing ranked lists of co-occurring drug terms in the BioASQ corpus. The ranked result lists of neurological drug terms co-occurring with terms from the epilepsy ontologies EpSO, ESSO, EPILONT, EPISEM and FENICS undergo further analysis. The source data to create the ranked lists of drug names is produced using the text mining workflows described in Mueller, Bernd and Hagelstein, Alexandra (2016) <doi:10.4126/FRL01-006408558>, Mueller, Bernd et al. (2017) <doi:10.1007/978-3-319-58694-6_22>, Mueller, Bernd and Rebholz-Schuhmann, Dietrich (2020) <doi:10.1007/978-3-030-43887-6_52>, and Mueller, Bernd et al. (2022) <doi:10.1186/s13326-021-00258-w>.

Predictors can be converted to one or more numeric representations using a variety of methods. Effect encodings using simple generalized linear models <doi:10.48550/arXiv.1611.09477> or nonlinear models <doi:10.48550/arXiv.1604.06737> can be used. There are also functions for dimension reduction and other approaches.

By using a multispectral image and ESRI shapefile (Point/ Line/ Polygon), a data table will be generated for classification, regression or other processing. The data table will be contained by band wise raster values and shapefile ids (User Defined).

This package contains methods for the estimation of Shannon's entropy, variants of Renyi's entropy, mutual information, Kullback-Leibler divergence, and generalized Simpson's indices. The estimators used have a bias that decays exponentially fast.

Work with Ecological Metadata Language ('EML') files. EML is a widely used metadata standard in the ecological and environmental sciences, described in Jones et al. (2006), <doi:10.1146/annurev.ecolsys.37.091305.110031>.

Multivariate modeling of data after deflation of interfering effects. EF Mosleth et al. (2021) <doi:10.1038/s41598-021-82388-w> and EF Mosleth et al. (2020) <doi:10.1016/B978-0-12-409547-2.14882-6>.

This package provides visual representations of risk-of-bias assessments using the ROBUST-RCT framework, as described in Wang et al. (2025) <doi:10.1136/bmj-2024-081199>. The graphical visualization displays both factual evaluation (Step 1) and judgment (Step 2).

Allows calculating global scores for characteristics of visual stimuli as assessed by human raters. Stimuli are presented as sequence of pairwise comparisons ('contests'), during each of which a rater expresses preference for one stimulus over the other (forced choice). The algorithm for calculating global scores is based on Elo rating, which updates individual scores after each single pairwise contest. Elo rating is widely used to rank chess players according to their performance. Its core feature is that dyadic contests with expected outcomes lead to smaller changes of participants scores than outcomes that were unexpected. As such, Elo rating is an efficient tool to rate individual stimuli when a large number of such stimuli are paired against each other in the context of experiments where the goal is to rank stimuli according to some characteristic of interest. Clark et al (2018) <doi:10.1371/journal.pone.0190393> provide details.

This package contains methods for observed-score linking and equating under the single-group, equivalent-groups, and nonequivalent-groups with anchor test(s) designs. Equating types include identity, mean, linear, general linear, equipercentile, circle-arc, and composites of these. Equating methods include synthetic, nominal weights, Tucker, Levine observed score, Levine true score, Braun/Holland, frequency estimation, and chained equating. Plotting and summary methods, and methods for multivariate presmoothing and bootstrap error estimation are also provided.

Import physiologic data stored in the European Data Format (EDF and EDF+) into R. Both EDF and EDF+ files are supported. Discontinuous EDF+ files are not yet supported.

Connect to Elasticsearch and OpenSearch', NoSQL databases built on the Java Virtual Machine and using the Apache Lucene library. Interacts with the Elasticsearch HTTP API (<https://www.elastic.co/elasticsearch/>) and the OpenSearch HTTP API (<https://opensearch.org/>). Includes functions for setting connection details to Elasticsearch and OpenSearch instances, loading bulk data, searching for documents with both HTTP query variables and JSON based body requests. In addition, elastic provides functions for interacting with APIs for indices', documents, nodes, clusters, an interface to the cat API, and more.

Estimates power by simulation for multivariate abundance data to be used for sample size estimates. Multivariate equivalence testing by simulation from a Gaussian copula model. The package also provides functions for parameterising multivariate effect sizes and simulating multivariate abundance data jointly. The discrete Gaussian copula approach is described in Popovic et al. (2018) <doi:10.1016/j.jmva.2017.12.002>.

This package implements Excel functions in R for your calculation simplicity.You can use most of the aggregate functions, addressing functions,logical functions and text functions. Helps you a ton in learning how R works as some Excel users might be struggling with the program.

Analysing data from evaluations of educational interventions using a randomised controlled trial design. Various analytical tools to perform sensitivity analysis using different methods are supported (e.g. frequentist models with bootstrapping and permutations options, Bayesian models). The included commands can be used for simple randomised trials, cluster randomised trials and multisite trials. The methods can also be used more widely beyond education trials. This package can be used to evaluate other intervention designs using Frequentist and Bayesian multilevel models.

Reliable and rapid ethnicity annotation from whole exome and targeted sequencing data.

Make your shiny application as executable program. Users do not need to install R and shiny on their system.

Null models to analyse ecological networks (e.g. food webs, flower-visitation networks, seed-dispersal networks) and detect resource preferences or non-random interactions among network nodes. Tools are provided to run null models, test for and plot preferences, plot and analyse bipartite networks, and export null model results in a form compatible with other network analysis packages. The underlying null model was developed by Agusti et al. (2003) Molecular Ecology <doi:10.1046/j.1365-294X.2003.02014.x> and the full application to ecological networks by Vaughan et al. (2018) econullnetr: an R package using null models to analyse the structure of ecological networks and identify resource selection. Methods in Ecology & Evolution, <doi:10.1111/2041-210X.12907>.

Fully robust versions of the elastic net estimator are introduced for linear and binary and multinomial regression, in particular high dimensional data. The algorithm searches for outlier free subsets on which the classical elastic net estimators can be applied. A reweighting step is added to improve the statistical efficiency of the proposed estimators. Selecting appropriate tuning parameters for elastic net penalties are done via cross-validation.

Conduct one- and two-sample goodness-of-fit tests for univariate data. In the one-sample case, normal, uniform, exponential, Bernoulli, binomial, geometric, beta, Poisson, lognormal, Laplace, asymmetric Laplace, inverse Gaussian, half-normal, chi-squared, gamma, F, Weibull, Cauchy, and Pareto distributions are supported. egof.test() can also test goodness-of-fit to any distribution with a continuous distribution function. A subset of the available distributions can be tested for the composite goodness-of-fit hypothesis, that is, one can test for distribution fit with unknown parameters. P-values are calculated via parametric bootstrap.

The epilogi variable selection algorithm is implemented for the case of continuous response and predictor variables. The relevant paper is: Lakiotaki K., Papadovasilakis Z., Lagani V., Fafalios S., Charonyktakis P., Tsagris M. and Tsamardinos I. (2023). "Automated machine learning for Genome Wide Association Studies". Bioinformatics, 39(9): btad545. <doi:10.1093/bioinformatics/btad545>.

Unsupervised, multivariate, binary clustering for meaningful annotation of data, taking into account the uncertainty in the data. A specific constructor for trajectory analysis in movement ecology yields behavioural annotation of trajectories based on estimated local measures of velocity and turning angle, eventually with solar position covariate as a daytime indicator, ("Expectation-Maximization Binary Clustering for Behavioural Annotation").