This package implements a Bayesian profile regression using a generalized linear mixed model as output model. The package allows for binary (probit mixed model) and continuous (linear mixed model) outcomes and both continuous and categorical clustering variables. The package utilizes RcppArmadillo and RcppDist for high-performance statistical computing in C++. For more details see Amestoy & al. (2025) <doi:10.48550/arXiv.2510.08304>.

Plots matrices of colours as grids of coloured squares - aka heatmaps, guaranteeing legible row and column names, without transformation of values, without re-ordering rows or columns, and without dendrograms.

Manipulation and analysis of phylogenetically simulated data sets and phylogenetically based analyses using GLS.

Executes simple parametric models for right-censored survival data. Functionality emulates capabilities in Minitab', including fitting right-censored data, assessing fit, plotting survival functions, and summary statistics and probabilities.

Pedigree related functions.

Priority-ElasticNet extends the Priority-LASSO method (Klau et al. (2018) <doi:10.1186/s12859-018-2344-6>) by incorporating the ElasticNet penalty, allowing for both L1 and L2 regularization. This approach fits successive ElasticNet models for several blocks of (omics) data with different priorities, using the predicted values from each block as an offset for the subsequent block. It also offers robust options to handle block-wise missingness in multi-omics data, improving the flexibility and applicability of the model in the presence of incomplete datasets.

This package provides a scalable and accurate tool for Killer-cell Immunoglobulin-like Receptor (KIR) genotype imputation directly from SNP array data using supervised machine learning models trained across five continental ancestry groups. Uses attribute bagging and an ensemble classifier method with haplotype inference for SNPs and KIR types. Models are built from global populations in the 1000 Genomes Project and validated across diverse biobank cohorts. Methods are based on Zheng et al. (2014) <doi:10.1016/j.ajhg.2013.12.015> and Sadeeq et al. (2026) <https://github.com/NormanLabUCD/PONG2>.

Perform flexible and quick calculations for Demand and Supply Planning, such as projected inventories and coverages, as well as replenishment plan. For any time bucket, daily, weekly or monthly, and any granularity level, product or group of products.

Implementation of the pattern recognition technique Principal Component Pursuit tailored to environmental health data, as described in Gibson et al (2022) <doi:10.1289/EHP10479>.

This package provides a clinical decision support system for sub-symptom threshold aerobic exercise (SSTAE) prescription in adolescents with persistent post-concussion symptoms (PPCS). Implements an evidence-based protocol derived from a systematic review of seven studies (Li, 2026; <doi:10.17605/osf.io/kvuf6>), encoding safety screening, Buffalo Concussion Treadmill Test (BCTT)-guided heart rate prescription, session-level progress tracking, and evidence disclosure using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) framework into an open-source tool for athletic trainers and clinicians. Designed to support implementation in resource-limited settings where BCTT equipment may be unavailable. GRADE certainty of evidence: LOW. For clinician use only; not a substitute for clinical judgement.

This package provides a curated taxonomic backbone of mammal species recorded in Peru, based on the checklist published by Pacheco and collaborators (2021) <doi:10.15381/rpb.v28i4.21019>. The package includes standardized species data, occurrence records by ecological regions, endemic status, and tools for validating and matching scientific names through exact and approximate string procedures. It is designed as a lightweight and reliable reference for ecological, environmental, biogeographical, and conservation workflows that require verified species information for Peruvian mammals.

Carrying out inferences about any linear combination of proportions and the ratio of two proportions.

Perform scale linking to establish relationships between instruments that measure similar constructs according to the PROsetta Stone methodology, as in Choi, Schalet, Cook, & Cella (2014) <doi:10.1037/a0035768>.

The progressify() function rewrites (transpiles) calls to sequential and parallel map-reduce functions such as base::lapply(), purrr::map(), foreach::foreach(), and plyr::llply() to signal progress updates. By combining this function with R's native pipe operator, you have a straightforward way to report progress on iterative computations with minimal refactoring, e.g. lapply(x, fcn) |> progressify() and purrr::map(x, fcn) |> progressify()'. It is compatible with the parallel-processing map-reduce packages future.apply', furrr', crossmap', foreach', doFuture', and futurize'. It also supports domain-specific packages including boot', fwb', lme4', partykit', sandwich', and SimDesign', e.g. boot::boot(data, stat, R) |> progressify()'.

Parallelized version of the "segment" function from Bioconductor package "DNAcopy", utilizing multi-core computation on host CPU.

This package provides a collection of utilities and ggplot2 extensions to assist with visualisations in genomic epidemiology. This includes the phylepic chart, a visual combination of a phylogenetic tree and a matched epidemic curve. The included ggplot2 extensions such as date axes binned by week are relevant for other applications in epidemiology and beyond. The approach is described in Suster et al. (2024) <doi:10.1101/2024.04.02.24305229>.

This package provides access to word predictability estimates using large language models (LLMs) based on transformer architectures via integration with the Hugging Face ecosystem <https://huggingface.co/>. The package interfaces with pre-trained neural networks and supports both causal/auto-regressive LLMs (e.g., GPT-2') and masked/bidirectional LLMs (e.g., BERT') to compute the probability of words, phrases, or tokens given their linguistic context. For details on GPT-2 and causal models, see Radford et al. (2019) <https://storage.prod.researchhub.com/uploads/papers/2020/06/01/language-models.pdf>, for details on BERT and masked models, see Devlin et al. (2019) <doi:10.48550/arXiv.1810.04805>. By enabling a straightforward estimation of word predictability, the package facilitates research in psycholinguistics, computational linguistics, and natural language processing (NLP).

Useful functions and workflows for proteomics quality control and data analysis of both limited proteolysis-coupled mass spectrometry (LiP-MS) (Feng et. al. (2014) <doi:10.1038/nbt.2999>) and regular bottom-up proteomics experiments. Data generated with search tools such as Spectronaut', MaxQuant and Proteome Discover can be easily used due to flexibility of functions.

This package provides a unified and user-friendly framework for applying the principal sufficient dimension reduction methods for both linear and nonlinear cases. The package has an extendable power by varying loss functions for the support vector machine, even for an user-defined arbitrary function, unless those are convex and differentiable everywhere over the support (Li et al. (2011) <doi:10.1214/11-AOS932>). Also, it provides a real-time sufficient dimension reduction update procedure using the principal least squares support vector machine (Artemiou et al. (2021) <doi:10.1016/j.patcog.2020.107768>).

Pivot easily by specifying rows, columns, values and split.

The Food and Agriculture Organization-56 Penman-Monteith is one of the important method for estimating evapotranspiration from vegetated land areas. This package helps to calculate reference evapotranspiration using the weather variables collected from weather station. Evapotranspiration is the process of water transfer from the land surface to the atmosphere through evaporation from soil and other surfaces and transpiration from plants. The package aims to support agricultural, hydrological, and environmental research by offering accurate and accessible reference evapotranspiration calculation. This package has been developed using concept of Córdova et al. (2015)<doi:10.1016/j.apm.2022.09.004> and Debnath et al. (2015) <doi:10.1007/s40710-015-0107-1>.

Makes it easier to create a Quarto website for an R package. Converts R documentation ('Rd') files into Quarto Markdown documents individually. Supports configuration via the _quarto.yml file and groups functions using roxygen2 family tags.

Cluster analysis via nonparametric density estimation is performed. Operationally, the kernel method is used throughout to estimate the density. Diagnostics methods for evaluating the quality of the clustering are available. The package includes also a routine to estimate the probability density function obtained by the kernel method, given a set of data with arbitrary dimensions.

This package provides a figure region is prepared, creating a plot region with suitable background color, grid lines or shadings, and providing axes and labeling if not suppressed. Subsequently, information carrying graphics elements can be added (points, lines, barplot with add=TRUE and so forth).