Differential partial correlation identification with the ridge and the fusion penalties.

This package provides tools to sort DICOM-format medical image files, and convert them to NIfTI-1 format.

An integrated toolset for the analysis of de novo (sporadic) genetic sequence variants. denovolyzeR implements a mutational model that estimates the probability of a de novo genetic variant arising in each human gene, from which one can infer the expected number of de novo variants in a given population size. Observed variant frequencies can then be compared against expectation in a Poisson framework. denovolyzeR provides a suite of functions to implement these analyses for the interpretation of de novo variation in human disease.

Graphical interface for loading datasets in RStudio from all installed (including unloaded) packages, also includes command line interfaces.

This package provides a wrapper for the DeepL API <https://developers.deepl.com/docs>, a web service for translating texts between different languages. A DeepL API developer account is required to use the service (see <https://www.deepl.com/pro#developer>).

The standard Difference-in-Differences (DID) setup involves two periods and two groups -- a treated group and untreated group. Many applications of DID methods involve more than two periods and have individuals that are treated at different points in time. This package contains tools for computing average treatment effect parameters in Difference in Differences setups with more than two periods and with variation in treatment timing using the methods developed in Callaway and Sant'Anna (2021) <doi:10.1016/j.jeconom.2020.12.001>. The main parameters are group-time average treatment effects which are the average treatment effect for a particular group at a a particular time. These can be aggregated into a fewer number of treatment effect parameters, and the package deals with the cases where there is selective treatment timing, dynamic treatment effects, calendar time effects, or combinations of these. There are also functions for testing the Difference in Differences assumption, and plotting group-time average treatment effects.

Using a Gaussian copula approach, this package generates simulated data mimicking a target real dataset. It supports normal, Poisson, empirical, and DESeq2 (negative binomial with size factors) marginal distributions. It uses an low-rank plus diagonal covariance matrix to efficiently generate omics-scale data. Methods are described in: Yang, Grant, and Brooks (2025) <doi:10.1101/2025.01.31.634335>.

This package provides a two-stage procedure for the denoising and clustering of stack of noisy images acquired over time. Clustering only assumes that the data contain an unknown but small number of dynamic features. The method first denoises the signals using local spatial and full temporal information. The clustering step uses the previous output to aggregate voxels based on the knowledge of their spatial neighborhood. Both steps use a single keytool based on the statistical comparison of the difference of two signals with the null signal. No assumption is therefore required on the shape of the signals. The data are assumed to be normally distributed (or at least follow a symmetric distribution) with a known constant variance. Working pixelwise, the method can be time-consuming depending on the size of the data-array but harnesses the power of multicore cpus.

Efficiently create dummies of all factors and character vectors in a data frame. Support is included for learning the categories on one data set (e.g., a training set) and deploying them on another (e.g., a test set).

Generate balanced factorial designs with crossed and nested random and fixed effects <https://github.com/mmrabe/designr>.

This package performs reference based multiple imputation of recurrent event data based on a negative binomial regression model, as described by Keene et al (2014) <doi:10.1002/pst.1624>.

Density ratio estimation. The estimated density ratio function can be used in many applications such as anomaly detection, change-point detection, covariate shift adaptation. The implemented methods are uLSIF (Hido et al. (2011) <doi:10.1007/s10115-010-0283-2>), RuLSIF (Yamada et al. (2011) <doi:10.1162/NECO_a_00442>), and KLIEP (Sugiyama et al. (2007) <doi:10.1007/s10463-008-0197-x>).

Inference by sequential Monte Carlo for dynamic tree regression and classification models with hooks provided for sequential design and optimization, fully online learning with drift, variable selection, and sensitivity analysis of inputs. Illustrative examples from the original dynamic trees paper (Gramacy, Taddy & Polson (2011); <doi:10.1198/jasa.2011.ap09769>) are facilitated by demos in the package; see demo(package="dynaTree").

This package performs an exploratory data analysis through a shiny interface. It includes basic methods such as the mean, median, mode, normality test, among others. It also includes clustering techniques such as Principal Components Analysis, Hierarchical Clustering and the K-Means Method.

It provides the subset operator for dist objects and a function to compute medoid(s) that are fully parallelized leveraging the RcppParallel package. It also provides functions for package developers to easily implement their own parallelized dist() function using a custom C++'-based distance function.

Estimates dose-response relations from summarized dose-response data and to combines them according to principles of (multivariate) random-effects models.

Offers functionality which provides methods for data analyses and cleaning that can be flexibly applied across multiple variables and in groups. These include cleaning accidental text, contingent calculations, counting missing data, and building summarizations of the data.

This package provides the ability to generate images from documents of different types. Three main features are provided: generating document thumbnails, performing visual tests of documents, and updating fields and tables of contents of a Microsoft Word or RTF document. Microsoft Word and/or LibreOffice must be installed on the machine. If Microsoft Word is available, it can produce PDF documents or images identical to the originals; otherwise LibreOffice is used and the rendering may sometimes differ from the original documents.

Implementation of selected Tidyverse functions within DataSHIELD', an open-source federated analysis solution in R. Currently, DataSHIELD contains very limited tools for data manipulation, so the aim of this package is to improve the researcher experience by implementing essential functions for data manipulation, including subsetting, filtering, grouping, and renaming variables. This is the server-side package which should be installed on the server holding the data, and is used in conjunction with the client-side package dsTidyverseClient which is installed in the local R environment of the analyst. For more information, see <https://tidyverse.org/> and <https://datashield.org/>.

This package provides friendly wrappers for creating duckdb'-backed connections to tabular datasets ('csv', parquet, etc) on local or remote file systems. This mimics the behaviour of "open_dataset" in the arrow package, but in addition to S3 file system also generalizes to any list of http URLs.

Perform a test of a simple null hypothesis about a directly standardized rate and obtain the matching confidence interval using a choice of methods.

This package provides a datetime range picker widget for usage in Shiny'. It creates a calendar allowing to select a start date and an end date as well as two fields allowing to select a start time and an end time.

This package provides functions are provided to fit temporal lag models to dynamic networks. The models are build on top of exponential random graph models (ERGM) framework. There are functions for simulating or forecasting networks for future time points. Abhirup Mallik & Zack W. Almquist (2019) Stable Multiple Time Step Simulation/Prediction From Lagged Dynamic Network Regression Models, Journal of Computational and Graphical Statistics, 28:4, 967-979, <DOI: 10.1080/10618600.2019.1594834>.

This package provides a collection of widely used univariate data sets of various applied domains on applications of distribution theory. The functions allow researchers and practitioners to quickly, easily, and efficiently access and use these data sets. The data are related to different applied domains and as follows: Bio-medical, survival analysis, medicine, reliability analysis, hydrology, actuarial science, operational research, meteorology, extreme values, quality control, engineering, finance, sports and economics. The total 100 data sets are documented along with associated references for further details and uses.