This package provides a central decision in a parametric regression is how to specify the relation between an dependent variable and each explanatory variable. This package provides a semi-parametric tool for comparing different transformations of an explanatory variables in a parametric regression. The functions is relevant in a situation, where you would use a box-cox or Box-Tidwell transformations. In contrast to the classic power-transformations, the methods in this package allows for theoretical driven user input and the possibility to compare with a non-parametric transformation.

Location- and scale-invariant Box-Cox and Yeo-Johnson power transformations allow for transforming variables with distributions distant from 0 to normality. Transformers are implemented as S4 objects. These allow for transforming new instances to normality after optimising fitting parameters on other data. A test for central normality allows for rejecting transformations that fail to produce a suitably normal distribution, independent of sample number.

Allows to parse Java properties files in the context of R Service Bus applications.

Extract and interact with data from the Scottish Health and Social Care Open Data platform <https://www.opendata.nhs.scot>.

This package creates a data frame with the residuals of partial regressions of the main explanatory variable and the variable of interest. This method follows the Frisch-Waugh-Lovell theorem, as explained in Lovell (2008) <doi:10.3200/JECE.39.1.88-91>.

This package provides functions for evaluating the mass density, cumulative distribution function, quantile function and random variate generation for the Polya-Aeppli distribution, also known as the geometric compound Poisson distribution. More information on the implementation can be found at Conrad J. Burden (2014) <arXiv:1406.2780>.

This package performs bivariate composite likelihood and full information maximum likelihood estimation for polytomous logit-normit (graded logistic) item response theory (IRT) models.

Read and write GraphPad Prism .pzfx files in R.

In each odd dimension is a convex body - the polar zonoid - whose generating functions are trigonometric polynomials. The polar zonoid is a straightforward generalization of the polar zonohedron in dimension 3, as defined by Chilton and Coxeter (1963) <doi:10.2307/2313051>. The package has some applications of the polar zonoid, including the properties of configuration spaces of arcs on the circle and 3x3 rotation matrices. There is also a root solver for trigonometric polynomials.

Predicts the most common race of a surname and based on U.S. Census data, and the most common first named based on U.S. Social Security Administration data.

Achieve internal conversions of mass units, molar units, and volume units commonly used in pharmacokinetics, as well as conversions between mass units and molar units.

Control Philips Hue smart lighting. Use this package to connect to a Hue bridge on your local network (remote authentication not yet supported) and control your smart lights through the Philips Hue API. All API V1 endpoints are supported. See API documentation at <https://developers.meethue.com/>.

This package provides methods for assessing the performance of a prediction model with respect to identifying patient-level treatment benefit. All methods are applicable for continuous and binary outcomes, and for any type of statistical or machine-learning prediction model as long as it uses baseline covariates to predict outcomes under treatment and control.

This package provides tools that allow developers to write functions for prediction error estimation with minimal programming effort and assist users with model selection in regression problems.

Data and utilities for estimating pediatric blood pressure percentiles by sex, age, and optionally height (stature) as described in Martin et.al. (2022) <doi:10.1001/jamanetworkopen.2022.36918>. Blood pressure percentiles for children under one year of age come from Gemelli et.al. (1990) <doi:10.1007/BF02171556>. Estimates of blood pressure percentiles for children at least one year of age are informed by data from the National Heart, Lung, and Blood Institute (NHLBI) and the Centers for Disease Control and Prevention (CDC) <doi:10.1542/peds.2009-2107C> or from Lo et.al. (2013) <doi:10.1542/peds.2012-1292>. The flowchart for selecting the informing data source comes from Martin et.al. (2022) <doi:10.1542/hpeds.2021-005998>.

Early generation breeding trials are to be conducted in multiple environments where it may not be possible to replicate all the lines in each environment due to scarcity of resources. For such situations, partially replicated (p-Rep) designs have wide application potential as only a proportion of the test lines are replicated at each environment. A collection of several utility functions related to p-Rep designs have been developed. Here, the package contains six functions for a complete stepwise analytical study of these designs. Five functions pRep1(), pRep2(), pRep3(), pRep4() and pRep5(), are used to generate five new series of p-Rep designs and also compute average variance factors and canonical efficiency factors of generated designs. A fourth function NCEV() is used to generate incidence matrix (N), information matrix (C), canonical efficiency factor (E) and average variance factor (V). This function is general in nature and can be used for studying the characterization properties of any block design. A construction procedure for p-Rep designs was given by Williams et al.(2011) <doi:10.1002/bimj.201000102> which was tedious and time consuming. Here, in this package, five different methods have been given to generate p-Rep designs easily.

Plots matrices of colours as grids of coloured squares - aka heatmaps, guaranteeing legible row and column names, without transformation of values, without re-ordering rows or columns, and without dendrograms.

Installs an updated version of pomdp-solve', a program to solve Partially Observable Markov Decision Processes (POMDPs) using a variety of exact and approximate value iteration algorithms. A convenient R infrastructure is provided in the separate package pomdp. Kaelbling, Littman and Cassandra (1998) <doi:10.1016/S0004-3702(98)00023-X>.

Estimation, hypothesis tests, and variable selection in partially linear single-index models. Please see H. (2010) at <doi:10.1214/10-AOS835> for more details.

Population dynamic models underpin a range of analyses and applications in ecology and epidemiology. The various approaches for analysing population dynamics models (MPMs, IPMs, ODEs, POMPs, PVA) each require the model to be defined in a different way. This makes it difficult to combine different modelling approaches and data types to solve a given problem. pop aims to provide a flexible and easy to use common interface for constructing population dynamic models and enabling to them to be fitted and analysed in lots of different ways.

Enables the creation of object pools, which make it less computationally expensive to fetch a new object. Currently the only supported pooled objects are DBI connections.

This package implements optimization techniques for Lasso regression, R.Tibshirani(1996)<doi:10.1111/j.2517-6161.1996.tb02080.x> using Fast Iterative Shrinkage-Thresholding Algorithm (FISTA) and Iterative Shrinkage-Thresholding Algorithm (ISTA) based on proximal operators, A.Beck(2009)<doi:10.1137/080716542>. The package is useful for high-dimensional regression problems and includes cross-validation procedures to select optimal penalty parameters.

An efficient data integration method is provided for multiple spatial transcriptomics data with non-cluster-relevant effects such as the complex batch effects. It unifies spatial factor analysis simultaneously with spatial clustering and embedding alignment, requiring only partially shared cell/domain clusters across datasets. More details can be referred to Wei Liu, et al. (2023) <doi:10.1038/s41467-023-35947-w>.

Implement surrogate-assisted feature extraction (SAFE) and common machine learning approaches to train and validate phenotyping models. Background and details about the methods can be found at Zhang et al. (2019) <doi:10.1038/s41596-019-0227-6>, Yu et al. (2017) <doi:10.1093/jamia/ocw135>, and Liao et al. (2015) <doi:10.1136/bmj.h1885>.