Computes the ACMIF test and Bonferroni-adjusted p-value of interaction in two-factor studies. Produces corresponding interaction plot and analysis of variance tables and p-values from several other tests of non-additivity.

This package implements marker-based estimation of heritability when observations on genetically identical replicates are available. These can be either observations on individual plants or plot-level data in a field trial. Heritability can then be estimated using a mixed model for the individual plant or plot data. For comparison, also mixed-model based estimation using genotypic means and estimation of repeatability with ANOVA are implemented. For illustration the package contains several datasets for the model species Arabidopsis thaliana.

This package provides a simple implementation of doughnut plots - pie charts with a blank center. The package is named after Homer Simpson - arguably the best-known lover of doughnuts.

Collection of functions to help retrieving data from Hub'Eau the free and public French National APIs on water <https://hubeau.eaufrance.fr/>.

This package provides flexible maximum likelihood estimation and inference for Hidden Markov Models (HMMs) and Hidden Semi-Markov Models (HSMMs), as well as the underlying systems in which they operate. The package supports a wide range of observation and dwell-time distributions, offering a flexible modelling framework suitable for diverse practical data. Efficient implementations of the forward-backward and Viterbi algorithms are provided via Rcpp for enhanced computational performance. Additional functionality includes model simulation, residual analysis, non-initialised estimation, local and global decoding, calculation of diverse information criteria, computation of confidence intervals using parametric bootstrap methods, numerical covariance matrix estimation, and comprehensive visualisation functions for interpreting the data-generating processes inferred from the models. Methods follow standard approaches described by Guédon (2003) <doi:10.1198/1061860032030>, Zucchini and MacDonald (2009, ISBN:9781584885733), and O'Connell and Højsgaard (2011) <doi:10.18637/jss.v039.i04>.

Package that simplifies the use of the HPZone API. Most of the annoying and labor-intensive parts of the interface are handled by wrapper functions. Note that the API and its details are not publicly available. Information can be found at <https://www.ggdghorkennisnet.nl/groep/726-platform-infectieziekte-epidemiologen/documenten/map/9609> for those with access.

Use the Official Hacker News API through R. Retrieve posts, articles and other items in form of convenient R objects.

The different methods for defining, detecting, and categorising the extreme events known as heatwaves or cold-spells, as first proposed in Hobday et al. (2016) <doi: 10.1016/j.pocean.2015.12.014> and Hobday et al. (2018) <https://www.jstor.org/stable/26542662>. The functions in this package work on both air and water temperature data of hourly and daily temporal resolution. These detection algorithms may be used on non-temperature data as well.

Estimates parameters in Mixture Transition Distribution (MTD) models, a class of high-order Markov chains. The set of relevant pasts (lags) is selected using either the Bayesian Information Criterion or the Forward Stepwise and Cut algorithms. Other model parameters (e.g. transition probabilities and oscillations) can be estimated via maximum likelihood estimation or the Expectation-Maximization algorithm. Additionally, hdMTD includes a perfect sampling algorithm that generates samples of an MTD model from its invariant distribution. For theory, see Ost & Takahashi (2023) <http://jmlr.org/papers/v24/22-0266.html>.

This package contains ten datasets used in the chapters and exercises of Paul, Alice (2023) "Health Data Science in R" <https://alicepaul.github.io/health-data-science-using-r/>.

This package provides tools to estimate, compare, and visualize healthcare resource utilization using data derived from electronic health records or real-world evidence sources. The package supports pre index and post index analysis, patient cohort comparison, and customizable summaries and visualizations for clinical and health economics research. Methods implemented are based on Scott et al. (2022) <doi:10.1080/13696998.2022.2037917> and Xia et al. (2024) <doi:10.14309/ajg.0000000000002901>.

This package provides interpretable high-dimensional mean comparison methods (HMC). For example, users can apply these methods to assess the difference in gene expression between two treatment groups. It is not a gene-by-gene comparison. Instead, the methods focus on the interplay between features and identify those that are predictive of the group label. The tests are valid frequentist procedures and yield sparse estimates indicating which features contribute to the group differences.

Inference of chromosome-length haplotypes using a few haploid gametes of an individual. The gamete genotype data may be generated from various platforms including genotyping arrays and sequencing even with low-coverage. Hapi simply takes genotype data of known hetSNPs in single gamete cells as input and report the high-resolution haplotypes as well as confidence of each phased hetSNPs. The package also includes a module allowing downstream analyses and visualization of identified crossovers in the gametes.

By analyzing time series, it is possible to observe significant changes in the behavior of observations that frequently characterize events. Events present themselves as anomalies, change points, or motifs. In the literature, there are several methods for detecting events. However, searching for a suitable time series method is a complex task, especially considering that the nature of events is often unknown. This work presents Harbinger, a framework for integrating and analyzing event detection methods. Harbinger contains several state-of-the-art methods described in Salles et al. (2020) <doi:10.5753/sbbd.2020.13626>.

High level functions for hyperplane fitting (hyper.fit()) and visualising (hyper.plot2d() / hyper.plot3d()). In simple terms this allows the user to produce robust 1D linear fits for 2D x vs y type data, and robust 2D plane fits to 3D x vs y vs z type data. This hyperplane fitting works generically for any N-1 hyperplane model being fit to a N dimension dataset. All fits include intrinsic scatter in the generative model orthogonal to the hyperplane.

Human names are complicated and nonstandard things. Humaniformat, which is based on Anthony Ettinger's humanparser project (https://github.com/ chovy/humanparser) provides functions for parsing human names, making a best- guess attempt to distinguish sub-components such as prefixes, suffixes, middle names and salutations.

Manipulate data through memory-mapped files, as vectors, matrices or arrays. Basic arithmetic functions are implemented, but currently no matrix arithmetic. Can write and read descriptor files for compatibility with the bigmemory package.

Inference approach for jointly modeling correlated count and binary outcomes. This formulation allows simultaneous modeling of zero inflation via the Bernoulli component while providing a more accurate assessment of the Hierarchical Zero-Inflated Poisson's parsimony (Lizandra C. Fabio, Jalmar M. F. Carrasco, Victor H. Lachos and Ming-Hui Chen, Likelihood-based inference for joint modeling of correlated count and binary outcomes with extra variability and zeros, 2025, under submission).

Develops algorithms for fitting, prediction, simulation and initialization of the following models (1)- hidden hybrid Markov/semi-Markov model, introduced by Guedon (2005) <doi:10.1016/j.csda.2004.05.033>, (2)- nonparametric mixture of B-splines emissions (Langrock et al., 2015 <doi:10.1111/biom.12282>), (3)- regime switching regression model (Kim et al., 2008 <doi:10.1016/j.jeconom.2007.10.002>) and auto-regressive hidden hybrid Markov/semi-Markov model, (4)- spline-based nonparametric estimation of additive state-switching models (Langrock et al., 2018 <doi:10.1111/stan.12133>) (5)- robust emission model proposed by Qin et al, 2024 <doi:10.1007/s10479-024-05989-4> (6)- several emission distributions, including mixture of multivariate normal (which can also handle missing data using EM algorithm) and multi-nomial emission (for modeling polymer or DNA sequences) (7)- tools for prediction of future state sequence, computing the score of a new sequence, splitting the samples and sequences to train and test sets, computing the information measures of the models, computing the residual useful lifetime (reliability) and many other useful tools ... (read for more description: Amini et al., 2022 <doi:10.1007/s00180-022-01248-x> and its arxiv version: <doi:10.48550/arXiv.2109.12489>).

By binding R functions and the Highmaps <https://www.highcharts.com.cn/products/highmaps> chart library, hchinamap package provides a simple way to map China and its provinces. The map of China drawn by this package contains complete Chinese territory, especially the Nine-dotted line, South Tibet, Hong Kong, Macao and Taiwan.

Efficient implementation of penalized regression with hierarchical nested parametrization for grouped data. The package provides penalized regression methods that decompose subgroup specific effects into shared global effects, Major subgroup specific effects, and Minor subgroup specific effects, enabling structured borrowing of information across related clinical subgroups. Both lasso and hierarchical overlapping group lasso penalties are supported to encourage sparsity while respecting the nested subgroup structure. Efficient computation is achieved through a modified design matrix representation and a custom algorithm for overlapping group penalties.

This package provides a novel decision tree algorithm in the hypothesis testing framework. The algorithm examines the distribution difference between two child nodes over all possible binary partitions. The test statistic of the hypothesis testing is equivalent to the generalized energy distance, which enables the algorithm to be more powerful in detecting the complex structure, not only the mean difference. It is applicable for numeric, nominal, ordinal explanatory variables and the response in general metric space of strong negative type. The algorithm has superior performance compared to other tree models in type I error, power, prediction accuracy, and complexity.

Allows to evaluate Higher Order Assortativity of complex networks defined through objects of class igraph from the package of the same name. The package returns a result also for directed and weighted graphs. References, Arcagni, A., Grassi, R., Stefani, S., & Torriero, A. (2017) <doi:10.1016/j.ejor.2017.04.028> Arcagni, A., Grassi, R., Stefani, S., & Torriero, A. (2021) <doi:10.1016/j.jbusres.2019.10.008> Arcagni, A., Cerqueti, R., & Grassi, R. (2023) <doi:10.48550/arXiv.2304.01737>.

Helping to calculate cricket specific problems in a tidy & simple manner.