This package provides functions for determining and evaluating high-risk zones and simulating and thinning point process data, as described in Determining high risk zones using point process methodology - Realization by building an R package Seibold (2012) <http://highriskzone.r-forge.r-project.org/Bachelorarbeit.pdf> and Determining high-risk zones for unexploded World War II bombs by using point process methodology', Mahling et al. (2013) <doi:10.1111/j.1467-9876.2012.01055.x>.

Tracks elapsed clock time using a `hms::hms()` scalar. It was was originally developed to time Bayesian model runs. It should not be used to estimate how long extremely fast code takes to execute as the package code adds a small time cost.

Using Dirichlet-Multinomial distribution to provide several functions for formal hypothesis testing, power and sample size calculations for human microbiome experiments.

Error type I and Optimal critical values to test statistical hypothesis based on Neyman-Pearson Lemma and Likelihood ratio test based on random samples from several distributions. The families of distributions are Bernoulli, Exponential, Geometric, Inverse Normal, Normal, Gamma, Gumbel, Lognormal, Poisson, and Weibull. This package is an ideal resource to help with the teaching of Statistics. The main references for this package are Casella G. and Berger R. (2003,ISBN:0-534-24312-6 , "Statistical Inference. Second Edition", Duxbury Press) and Hogg, R., McKean, J., and Craig, A. (2019,ISBN:013468699, "Introduction to Mathematical Statistic. Eighth edition", Pearson).

Homomorphic computations in R for privacy-preserving applications. Currently only the Paillier Scheme is implemented.

This package contains functions for hidden Markov models with observations having extra zeros as defined in the following two publications, Wang, T., Zhuang, J., Obara, K. and Tsuruoka, H. (2016) <doi:10.1111/rssc.12194>; Wang, T., Zhuang, J., Buckby, J., Obara, K. and Tsuruoka, H. (2018) <doi:10.1029/2017JB015360>. The observed response variable is either univariate or bivariate Gaussian conditioning on presence of events, and extra zeros mean that the response variable takes on the value zero if nothing is happening. Hence the response is modelled as a mixture distribution of a Bernoulli variable and a continuous variable. That is, if the Bernoulli variable takes on the value 1, then the response variable is Gaussian, and if the Bernoulli variable takes on the value 0, then the response is zero too. This package includes functions for simulation, parameter estimation, goodness-of-fit, the Viterbi algorithm, and plotting the classified 2-D data. Some of the functions in the package are based on those of the R package HiddenMarkov by David Harte. This updated version has included an example dataset and R code examples to show how to transform the data into the objects needed in the main functions. We have also made changes to increase the speed of some of the functions.

Inference of chromosome-length haplotypes using a few haploid gametes of an individual. The gamete genotype data may be generated from various platforms including genotyping arrays and sequencing even with low-coverage. Hapi simply takes genotype data of known hetSNPs in single gamete cells as input and report the high-resolution haplotypes as well as confidence of each phased hetSNPs. The package also includes a module allowing downstream analyses and visualization of identified crossovers in the gametes.

Generates high-entropy integer synthetic populations from marginal and (optionally) seed data using quasirandom sampling, in arbitrary dimensionality (Smith, Lovelace and Birkin (2017) <doi:10.18564/jasss.3550>). The package also provides an implementation of the Iterative Proportional Fitting (IPF) algorithm (Zaloznik (2011) <doi:10.13140/2.1.2480.9923>).

EQ-5D value set estimation can be done using the hybrid model likelihood as described by Oppe and van Hout (2010) <doi:10.1002/hec.3560> and Ramos-Goñi et al. (2017) <doi:10.1097/MLR.0000000000000283>. The package is based on flexmix and among others contains an M-step-driver as described by Leisch (2004) <doi:10.18637/jss.v011.i08>. Users can estimate latent classes and address preference heterogeneity. Both uncensored and censored data are supported. Furthermore, heteroscedasticity can be taken into account. It is possible to control for different covariates on the continuous and dichotomous parts of the data and start values can differ between the expected latent classes.

This package provides functions for specifying and fitting marginal models for contingency tables proposed by Bergsma and Rudas (2002) <doi:10.1214/aos/1015362188> here called hierarchical multinomial marginal models (hmmm) and their extensions presented by Bartolucci, Colombi and Forcina (2007) <https://www.jstor.org/stable/24307737>; multinomial Poisson homogeneous (mph) models and homogeneous linear predictor (hlp) models for contingency tables proposed by Lang (2004) <doi:10.1214/aos/1079120140> and Lang (2005) <doi:10.1198/016214504000001042>. Inequality constraints on the parameters are allowed and can be tested.

This package provides a set of objects and functions for Bayes Linear emulation and history matching. Core functionality includes automated training of emulators to data, diagnostic functions to ensure suitability, and a variety of proposal methods for generating waves of points. For details on the mathematical background, there are many papers available on the topic (see references attached to function help files or the below references); for details of the functions in this package, consult the manual or help files. Iskauskas, A, et al. (2024) <doi:10.18637/jss.v109.i10>. Bower, R.G., Goldstein, M., and Vernon, I. (2010) <doi:10.1214/10-BA524>. Craig, P.S., Goldstein, M., Seheult, A.H., and Smith, J.A. (1997) <doi:10.1007/978-1-4612-2290-3_2>.

This package provides tools for emitting the Problem Details structure defined in RFC 7807 <https://tools.ietf.org/html/rfc7807> for reporting errors from HTTP servers in a standard way.

This package implements hierarchical conformal prediction for clustered data with missing responses. The method uses repeated cluster-level splitting and within-cluster subsampling to accommodate dependence, and inverse-probability weighting to correct distribution shift induced by missingness. Conditional densities are estimated by inverting fitted conditional quantiles (linear quantile regression or quantile regression forests), and p-values are aggregated across resampling and splitting steps using the Cauchy combination test.

LecÈ iile prof/cls trebuie completate cu un câmp "ora", astfel ca oricare douÄ lecÈ ii prof/cls/ora sÄ nu se suprapunÄ Ã®ntr-o aceeaÈ i orÄ . The prof/cls lessons must be completed with a "hour" field ('ora), so that any two prof/cls/ora lessons do not overlap in the same hour. <https://vlad.bazon.net/>.

This package provides a function to assess and test for heterogeneity in the utility of a surrogate marker with respect to a baseline covariate. The main function can be used for either a continuous or discrete baseline covariate. More details will be available in the future in: Parast, L., Cai, T., Tian L (2021). "Testing for Heterogeneity in the Utility of a Surrogate Marker." Biometrics, In press.

Identification of recombination events, haplotype reconstruction, sire imputation and pedigree reconstruction using half-sib family SNP data.

Perform forensic handwriting analysis of two scanned handwritten documents. This package implements the statistical method described by Madeline Johnson and Danica Ommen (2021) <doi:10.1002/sam.11566>. Similarity measures and a random forest produce a score-based likelihood ratio that quantifies the strength of the evidence in favor of the documents being written by the same writer or different writers.

This package provides a collection of datasets and supporting functions accompanying Health Metrics and the Spread of Infectious Diseases by Federica Gazzelloni (2024). This package provides data for health metrics calculations, including Disability-Adjusted Life Years (DALYs), Years of Life Lost (YLLs), and Years Lived with Disability (YLDs), as well as additional tools for analyzing and visualizing health data. Federica Gazzelloni (2024) <doi:10.5281/zenodo.10818338>.

Unsupervised multivariate filter feature selection using the UFS-rHCM or UFS-cHCM algorithms based on the heterogeneous correlation matrix (HCM). The HCM consists of Pearson's correlations between numerical features, polyserial correlations between numerical and ordinal features, and polychoric correlations between ordinal features. Tortora C., Madhvani S., Punzo A. (2025). "Designing unsupervised mixed-type feature selection techniques using the heterogeneous correlation matrix." International Statistical Review <doi:10.1111/insr.70016>. This work was supported by the National Science foundation NSF Grant N 2209974 (Tortora) and by the Italian Ministry of University and Research (MUR) under the PRIN 2022 grant number 2022XRHT8R (CUP: E53D23005950006), as part of â The SMILE Project: Statistical Modelling and Inference to Live the Environmentâ , funded by the European Union â Next Generation EU (Punzo).

Identifies regime changes in streamflow runoff not explained by variations in precipitation. The package builds a flexible set of Hidden Markov Models of annual, seasonal or monthly streamflow runoff with precipitation as a predictor. Suites of models can be built for a single site, ranging from one to three states and each with differing combinations of error models and auto-correlation terms. The most parsimonious model is easily identified by AIC, and useful for understanding catchment drought non-recovery: Peterson TJ, Saft M, Peel MC & John A (2021) <doi:10.1126/science.abd5085>.

Convert a html document to plain texts by stripping off all html tags.

An implementation of Random Forest-based two-sample tests as introduced in Hediger & Michel & Naef (2022).

This package contains functions for fitting hierarchical versions of EVSD, UVSD, DPSD, DPSD with d restricted to be positive, and our gamma signal detection model to recognition memory confidence-ratings data.

This package performs genetic association analyses of case-parent triad (trio) data with multiple markers. It can also incorporate complete or incomplete control triads, for instance independent control children. Estimation is based on haplotypes, for instance SNP haplotypes, even though phase is not known from the genetic data. Haplin estimates relative risk (RR + conf.int.) and p-value associated with each haplotype. It uses maximum likelihood estimation to make optimal use of data from triads with missing genotypic data, for instance if some SNPs has not been typed for some individuals. Haplin also allows estimation of effects of maternal haplotypes and parent-of-origin effects, particularly appropriate in perinatal epidemiology. Haplin allows special models, like X-inactivation, to be fitted on the X-chromosome. A GxE analysis allows testing interactions between environment and all estimated genetic effects. The models were originally described in "Gjessing HK and Lie RT. Case-parent triads: Estimating single- and double-dose effects of fetal and maternal disease gene haplotypes. Annals of Human Genetics (2006) 70, pp. 382-396".